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Refractory Kaposi Sarcoma

MedGen UID:
1670331
•Concept ID:
C4744849
•
Neoplastic Process

Definition

Kaposi sarcoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Kaposi Sarcoma

Professional guidelines

PubMed

Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis.
Putra J, Gupta A
Pathology 2017 Jun;49(4):356-362. Epub 2017 Apr 21 doi: 10.1016/j.pathol.2017.03.001. PMID: 28438388
Anti-viral treatment and cancer control.
Shih WL, Fang CT, Chen PJ
Recent Results Cancer Res 2014;193:269-90. doi: 10.1007/978-3-642-38965-8_14. PMID: 24008303
Gemcitabine for the treatment of classic Kaposi's Sarcoma: a case series.
Zustovich F, Ferro A, Toso S
Anticancer Res 2013 Dec;33(12):5531-4. PMID: 24324093

Recent clinical studies

Etiology

Cardiac safety analysis of first-line chemotherapy drug pegylated liposomal doxorubicin in ovarian cancer.
Li XR, Cheng XH, Zhang GN, Wang XX, Huang JM
J Ovarian Res 2022 Aug 16;15(1):96. doi: 10.1186/s13048-022-01029-6. PMID: 35971131Free PMC Article
Long-term outcomes for children and adolescents with Kaposi sarcoma.
Silverstein A, Kamiyango W, Villiera J, Peckham-Gregory EC, McAtee CL, Scheurer ME, Cox CM, Kovarik CL, Campbell LR, Allen CE, Mehta PS, Kazembe PN, Ozuah NW, El-Mallawany NK
HIV Med 2022 Feb;23(2):197-203. Epub 2021 Oct 11 doi: 10.1111/hiv.13191. PMID: 34634187Free PMC Article
Hematologic cancers in individuals infected by HIV.
Carbone A, Vaccher E, Gloghini A
Blood 2022 Feb 17;139(7):995-1012. doi: 10.1182/blood.2020005469. PMID: 34469512
Pilot Trial AMC-063: Safety and Efficacy of Bortezomib in AIDS-associated Kaposi Sarcoma.
Reid EG, Suazo A, Lensing SY, Dittmer DP, Ambinder RF, Maldarelli F, Gorelick RJ, Aboulafia D, Mitsuyasu R, Dickson MA, Wachsman W; AIDS Malignancy Consortium (AMC)
Clin Cancer Res 2020 Feb 1;26(3):558-565. Epub 2019 Oct 17 doi: 10.1158/1078-0432.CCR-19-1044. PMID: 31624104Free PMC Article
Alitretinoin.
Cheer SM, Foster RH
Am J Clin Dermatol 2000 Sep-Oct;1(5):307-14; discussion 315-6. doi: 10.2165/00128071-200001050-00005. PMID: 11702321

Diagnosis

Long-term outcomes for children and adolescents with Kaposi sarcoma.
Silverstein A, Kamiyango W, Villiera J, Peckham-Gregory EC, McAtee CL, Scheurer ME, Cox CM, Kovarik CL, Campbell LR, Allen CE, Mehta PS, Kazembe PN, Ozuah NW, El-Mallawany NK
HIV Med 2022 Feb;23(2):197-203. Epub 2021 Oct 11 doi: 10.1111/hiv.13191. PMID: 34634187Free PMC Article
Expression of Programmed Cell Death Proteins in Kaposi Sarcoma and Cutaneous Angiosarcoma.
Gambichler T, Koim S, Wrobel M, Käfferlein HU, Brüning T, Stockfleth E, Becker JC, Lang K
J Immunother 2020 Jun;43(5):169-174. doi: 10.1097/CJI.0000000000000317. PMID: 32224717
Kaposiform lymphangiomatosis and kaposiform hemangioendothelioma: similarities and differences.
Ji Y, Chen S, Peng S, Xia C, Li L
Orphanet J Rare Dis 2019 Jul 5;14(1):165. doi: 10.1186/s13023-019-1147-9. PMID: 31277673Free PMC Article
Refractory Thrombotic Thrombocytopenic Purpura in a patient with Kaposi sarcoma.
Sahin O, Albayrak M, Yıldız A, Pala Ç, Aktas L, Maral S, Afacan Öztürk HB, Cömert P
Transfus Apher Sci 2019 Apr;58(2):187-189. Epub 2019 Mar 19 doi: 10.1016/j.transci.2019.02.003. PMID: 30910619
Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis.
Putra J, Gupta A
Pathology 2017 Jun;49(4):356-362. Epub 2017 Apr 21 doi: 10.1016/j.pathol.2017.03.001. PMID: 28438388

Therapy

Immune checkpoint inhibitors to treat cutaneous malignancies.
Barrios DM, Do MH, Phillips GS, Postow MA, Akaike T, Nghiem P, Lacouture ME
J Am Acad Dermatol 2020 Nov;83(5):1239-1253. Epub 2020 May 24 doi: 10.1016/j.jaad.2020.03.131. PMID: 32461079Free PMC Article
Anti-viral treatment and cancer control.
Shih WL, Fang CT, Chen PJ
Recent Results Cancer Res 2014;193:269-90. doi: 10.1007/978-3-642-38965-8_14. PMID: 24008303
Paclitaxel in cancer therapy.
Mekhail TM, Markman M
Expert Opin Pharmacother 2002 Jun;3(6):755-66. doi: 10.1517/14656566.3.6.755. PMID: 12036415
Thalidomide in cancer.
Singhal S, Mehta J
Biomed Pharmacother 2002 Feb;56(1):4-12. doi: 10.1016/s0753-3322(01)00146-9. PMID: 11905508
Alitretinoin.
Cheer SM, Foster RH
Am J Clin Dermatol 2000 Sep-Oct;1(5):307-14; discussion 315-6. doi: 10.2165/00128071-200001050-00005. PMID: 11702321

Prognosis

Cardiac safety analysis of first-line chemotherapy drug pegylated liposomal doxorubicin in ovarian cancer.
Li XR, Cheng XH, Zhang GN, Wang XX, Huang JM
J Ovarian Res 2022 Aug 16;15(1):96. doi: 10.1186/s13048-022-01029-6. PMID: 35971131Free PMC Article
Immune checkpoint inhibitors to treat cutaneous malignancies.
Barrios DM, Do MH, Phillips GS, Postow MA, Akaike T, Nghiem P, Lacouture ME
J Am Acad Dermatol 2020 Nov;83(5):1239-1253. Epub 2020 May 24 doi: 10.1016/j.jaad.2020.03.131. PMID: 32461079Free PMC Article
Kaposiform lymphangiomatosis and kaposiform hemangioendothelioma: similarities and differences.
Ji Y, Chen S, Peng S, Xia C, Li L
Orphanet J Rare Dis 2019 Jul 5;14(1):165. doi: 10.1186/s13023-019-1147-9. PMID: 31277673Free PMC Article
Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis.
Putra J, Gupta A
Pathology 2017 Jun;49(4):356-362. Epub 2017 Apr 21 doi: 10.1016/j.pathol.2017.03.001. PMID: 28438388
Paclitaxel for AIDS-associated Kaposi's sarcoma.
Dhillon T, Stebbing J, Bower M
Expert Rev Anticancer Ther 2005 Apr;5(2):215-9. doi: 10.1586/14737140.5.2.215. PMID: 15877519

Clinical prediction guides

Immune checkpoint inhibitors to treat cutaneous malignancies.
Barrios DM, Do MH, Phillips GS, Postow MA, Akaike T, Nghiem P, Lacouture ME
J Am Acad Dermatol 2020 Nov;83(5):1239-1253. Epub 2020 May 24 doi: 10.1016/j.jaad.2020.03.131. PMID: 32461079Free PMC Article
Kaposiform lymphangiomatosis and kaposiform hemangioendothelioma: similarities and differences.
Ji Y, Chen S, Peng S, Xia C, Li L
Orphanet J Rare Dis 2019 Jul 5;14(1):165. doi: 10.1186/s13023-019-1147-9. PMID: 31277673Free PMC Article
STAT3 Regulates Lytic Activation of Kaposi's Sarcoma-Associated Herpesvirus.
King CA, Li X, Barbachano-Guerrero A, Bhaduri-McIntosh S
J Virol 2015 Nov;89(22):11347-55. Epub 2015 Sep 2 doi: 10.1128/JVI.02008-15. PMID: 26339061Free PMC Article
Polyethylene glycol-liposomal doxorubicin: a review of its use in the management of solid and haematological malignancies and AIDS-related Kaposi's sarcoma.
Sharpe M, Easthope SE, Keating GM, Lamb HM
Drugs 2002;62(14):2089-126. doi: 10.2165/00003495-200262140-00012. PMID: 12269857
Alitretinoin.
Cheer SM, Foster RH
Am J Clin Dermatol 2000 Sep-Oct;1(5):307-14; discussion 315-6. doi: 10.2165/00128071-200001050-00005. PMID: 11702321

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