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Pelvic Undifferentiated High Grade Pleomorphic Sarcoma

MedGen UID:
1670911
•Concept ID:
C4726600
•
Neoplastic Process
Synonym: Undifferentiated High Grade Pleomorphic Sarcoma of the Pelvis

Definition

Undifferentiated high grade pleomorphic sarcoma involving the bones of the pelvis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPelvic Undifferentiated High Grade Pleomorphic Sarcoma

Professional guidelines

PubMed

Spermatic cord sarcoma: outcome, patterns of failure and management.
Ballo MT, Zagars GK, Pisters PW, Feig BW, Patel SR, von Eschenbach AC
J Urol 2001 Oct;166(4):1306-10. doi: 10.1016/s0022-5347(05)65758-8. PMID: 11547063
The management of malignant bone tumors in children and adolescents.
Mercuri M, Capanna R, Manfrini M, Bacci G, Picci P, Ruggieri P, Ferruzzi A, Ferraro A, Donati D, Biagini R
Clin Orthop Relat Res 1991 Mar;(264):156-68. PMID: 1997230
Ewing's sarcoma. A retrospective study of prognostic factors and treatment results.
Daugaard S, Sunde LM, Kamby C, Schiødt T, Jensen OM
Acta Oncol 1987;26(4):281-7. doi: 10.3109/02841868709089976. PMID: 3689582

Recent clinical studies

Etiology

From Morphea to Dermatofibrosarcoma Protuberans.
Crnarić I, Šitum M, Delaš Aždajić M, Vučić M, Buljan M
Acta Dermatovenerol Croat 2022 Sep;30(2):113-115. PMID: 36254545
Uterine sarcomas and rare uterine mesenchymal tumors with malignant potential. Diagnostic guidelines of the French Sarcoma Group and the Rare Gynecological Tumors Group.
Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C
Gynecol Oncol 2022 Nov;167(2):373-389. Epub 2022 Sep 14 doi: 10.1016/j.ygyno.2022.07.031. PMID: 36114030
Soft-Tissue Sarcomas of the Abdomen and Pelvis: Radiologic-Pathologic Features, Part 2-Uncommon Sarcomas.
Levy AD, Manning MA, Miettinen MM
Radiographics 2017 May-Jun;37(3):797-812. doi: 10.1148/rg.2017160201. PMID: 28493803Free PMC Article
Dedifferentiated central chondrosarcoma.
Staals EL, Bacchini P, Bertoni F
Cancer 2006 Jun 15;106(12):2682-91. doi: 10.1002/cncr.21936. PMID: 16691621
Retroperitoneal sarcomas.
Eilber FC, Eilber KS, Eilber FR
Curr Treat Options Oncol 2000 Aug;1(3):274-8. doi: 10.1007/s11864-000-0040-y. PMID: 12057171

Diagnosis

Uterine sarcomas and rare uterine mesenchymal tumors with malignant potential. Diagnostic guidelines of the French Sarcoma Group and the Rare Gynecological Tumors Group.
Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C
Gynecol Oncol 2022 Nov;167(2):373-389. Epub 2022 Sep 14 doi: 10.1016/j.ygyno.2022.07.031. PMID: 36114030
Abdominal and pelvic tumors with musculoskeletal histology.
Dyrstad SW, Fowler AM, Jokerst CE, Baker JC, Hillen TJ, Menias C
Curr Probl Diagn Radiol 2014 Mar-Apr;43(2):68-79. doi: 10.1067/j.cpradiol.2013.11.001. PMID: 24629660
Malignant bone tumors.
Weber K, Damron TA, Frassica FJ, Sim FH
Instr Course Lect 2008;57:673-88. PMID: 18399615
Dedifferentiated central chondrosarcoma.
Staals EL, Bacchini P, Bertoni F
Cancer 2006 Jun 15;106(12):2682-91. doi: 10.1002/cncr.21936. PMID: 16691621
Retroperitoneal sarcomas.
Eilber FC, Eilber KS, Eilber FR
Curr Treat Options Oncol 2000 Aug;1(3):274-8. doi: 10.1007/s11864-000-0040-y. PMID: 12057171

Therapy

Melorheostosis: A Review of the Literature and a Case Report.
Iordache S, Cursaru A, Serban B, Costache M, Spiridonica R, Cretu B, Cirstoiu C
Medicina (Kaunas) 2023 Apr 30;59(5) doi: 10.3390/medicina59050869. PMID: 37241101Free PMC Article
Multidisciplinary approach to rare primary cardiac sarcoma: a case report and review.
Vaitiekiene A, Vaitiekus D, Urbonaite L, Jankauskas A, Portacenko J, Lapinskas T, Benetis R, Siudikas A, Veikutiene A, Poskiene L, Kavoliuniene A, Janciauskiene R, Jarusevicius L, Juozaityte E, Zaliunas R, Ereminiene E
BMC Cancer 2019 May 31;19(1):529. doi: 10.1186/s12885-019-5705-2. PMID: 31151427Free PMC Article
Clinical report on transarterial neoadjuvant chemotherapy of malignant fibrous histiocytoma in soft tissue.
Guo J, Cui Q, Liu C, Sui J, Jiang N, Zhou J, Li D, Zeng Y
Clin Transl Oncol 2013 May;15(5):370-5. Epub 2012 Sep 14 doi: 10.1007/s12094-012-0933-9. PMID: 22975901
Retroperitoneal sarcomas.
Eilber FC, Eilber KS, Eilber FR
Curr Treat Options Oncol 2000 Aug;1(3):274-8. doi: 10.1007/s11864-000-0040-y. PMID: 12057171
Postradiation sarcomas of bone.
Huvos AG, Woodard HQ
Health Phys 1988 Oct;55(4):631-6. doi: 10.1097/00004032-198810000-00004. PMID: 2844696

Prognosis

Melorheostosis: A Review of the Literature and a Case Report.
Iordache S, Cursaru A, Serban B, Costache M, Spiridonica R, Cretu B, Cirstoiu C
Medicina (Kaunas) 2023 Apr 30;59(5) doi: 10.3390/medicina59050869. PMID: 37241101Free PMC Article
Abdominal and pelvic tumors with musculoskeletal histology.
Dyrstad SW, Fowler AM, Jokerst CE, Baker JC, Hillen TJ, Menias C
Curr Probl Diagn Radiol 2014 Mar-Apr;43(2):68-79. doi: 10.1067/j.cpradiol.2013.11.001. PMID: 24629660
Malignant bone tumors.
Weber K, Damron TA, Frassica FJ, Sim FH
Instr Course Lect 2008;57:673-88. PMID: 18399615
Dedifferentiated central chondrosarcoma.
Staals EL, Bacchini P, Bertoni F
Cancer 2006 Jun 15;106(12):2682-91. doi: 10.1002/cncr.21936. PMID: 16691621
Retroperitoneal sarcomas.
Eilber FC, Eilber KS, Eilber FR
Curr Treat Options Oncol 2000 Aug;1(3):274-8. doi: 10.1007/s11864-000-0040-y. PMID: 12057171

Clinical prediction guides

Uterine sarcomas and rare uterine mesenchymal tumors with malignant potential. Diagnostic guidelines of the French Sarcoma Group and the Rare Gynecological Tumors Group.
Croce S, Devouassoux-Shisheboran M, Pautier P, Ray-Coquard I, Treilleux I, Neuville A, Arnould L, Just PA, Belda MALF, Averous G, Leroux A, Mery E, Loussouarn D, Weinbreck N, Le Guellec S, Mishellany F, Morice P, Guyon F, Genestie C
Gynecol Oncol 2022 Nov;167(2):373-389. Epub 2022 Sep 14 doi: 10.1016/j.ygyno.2022.07.031. PMID: 36114030
Surgical management of primary undifferentiated pleomorphic sarcoma of the rectum: a case report and review of the literature.
Kodera K, Hoshino M, Takahashi S, Hidaka S, Kogo M, Hashizume R, Imakita T, Ishiyama M, Ogawa M, Eto K
World J Surg Oncol 2022 Jun 13;20(1):199. doi: 10.1186/s12957-022-02671-6. PMID: 35698131Free PMC Article
Extra-articular resection is a limb-salvage option for sarcoma involving the hip joint.
Li D, Xie L, Guo W, Tang X, Ji T, Yang R
Int Orthop 2018 Mar;42(3):695-703. Epub 2018 Feb 5 doi: 10.1007/s00264-018-3771-8. PMID: 29404667
Gene expression profiling in leiomyosarcomas and undifferentiated pleomorphic sarcomas: SRC as a new diagnostic marker.
Villacis RA, Silveira SM, Barros-Filho MC, Marchi FA, Domingues MA, Scapulatempo-Neto C, Aguiar S Jr, Lopes A, Cunha IW, Rogatto SR
PLoS One 2014;9(7):e102281. Epub 2014 Jul 16 doi: 10.1371/journal.pone.0102281. PMID: 25028927Free PMC Article
Retroperitoneal and truncal sarcomas: prognosis depends upon type not location.
Perez EA, Gutierrez JC, Moffat FL Jr, Franceschi D, Livingstone AS, Spector SA, Levi JU, Sleeman D, Koniaris LG
Ann Surg Oncol 2007 Mar;14(3):1114-22. Epub 2007 Jan 7 doi: 10.1245/s10434-006-9255-x. PMID: 17206483

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