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Infantile constant exotropia

MedGen UID:
1671056
•Concept ID:
C4732800
•
Disease or Syndrome
Synonym: Infantile (constant) exotropia
 
HPO: HP:0032009

Definition

Constant exotropia occurring before 6 months of age.; often associated with a large angle of deviation and ocular/CNS abnormalities. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfantile constant exotropia

Recent clinical studies

Etiology

Abnormal biorbital angle in children with infantile exotropia.
Tsukui M, Yagasaki T, Yokoyama Y
Jpn J Ophthalmol 2022 Jan;66(1):81-86. Epub 2021 Oct 19 doi: 10.1007/s10384-021-00881-1. PMID: 34665373
Motor and Sensory Outcomes of Infantile Exotropia: A 10-Year Study (2008-2017).
Rajavi Z, Sabbaghi H, Behradfar N, Abdi S, Bahraini R, Kheiri B, Sheibani K
Korean J Ophthalmol 2020 Apr;34(2):143-149. doi: 10.3341/kjo.2019.0090. PMID: 32233148Free PMC Article
Spontaneous consecutive esotropia.
Voide N, Robert MP
Eye (Lond) 2018 Jul;32(7):1197-1200. Epub 2018 Mar 2 doi: 10.1038/s41433-018-0060-0. PMID: 29497134Free PMC Article
Early versus late surgery for infantile exotropia.
Na KH, Kim SH
J AAPOS 2018 Feb;22(1):3-6. Epub 2017 Nov 20 doi: 10.1016/j.jaapos.2017.08.006. PMID: 29158152
Everyday Exotropia: Learning from the Littlest.
Petrunak JL
Am Orthopt J 2017 Jan;67(1):52-60. doi: 10.3368/aoj.67.1.52. PMID: 28904215

Diagnosis

Abnormal biorbital angle in children with infantile exotropia.
Tsukui M, Yagasaki T, Yokoyama Y
Jpn J Ophthalmol 2022 Jan;66(1):81-86. Epub 2021 Oct 19 doi: 10.1007/s10384-021-00881-1. PMID: 34665373
Everyday Exotropia: Learning from the Littlest.
Petrunak JL
Am Orthopt J 2017 Jan;67(1):52-60. doi: 10.3368/aoj.67.1.52. PMID: 28904215
Comparison of Clinical Features and Long-term Surgical Outcomes in Infantile Constant and Intermittent Exotropia.
Na KH, Kim SH
J Pediatr Ophthalmol Strabismus 2016 Mar-Apr;53(2):99-104. Epub 2016 Feb 4 doi: 10.3928/01913913-20160122-05. PMID: 26848593
Prevalence of systemic and ocular disease in infantile exotropia: comparison with infantile esotropia.
Hunter DG, Ellis FJ
Ophthalmology 1999 Oct;106(10):1951-6. doi: 10.1016/S0161-6420(99)90407-4. PMID: 10519591
Infantile exotropia.
Biglan AW, Davis JS, Cheng KP, Pettapiece MC
J Pediatr Ophthalmol Strabismus 1996 Mar-Apr;33(2):79-84. doi: 10.3928/0191-3913-19960301-04. PMID: 8965243

Therapy

Prevalence of systemic and ocular disease in infantile exotropia: comparison with infantile esotropia.
Hunter DG, Ellis FJ
Ophthalmology 1999 Oct;106(10):1951-6. doi: 10.1016/S0161-6420(99)90407-4. PMID: 10519591
Lens correction of infantile myopia in identical twins: a case report.
Berman M, Schroder J, St Louis R
Am J Optom Physiol Opt 1977 Feb;54(2):107-10. doi: 10.1097/00006324-197702000-00007. PMID: 869004

Prognosis

Abnormal biorbital angle in children with infantile exotropia.
Tsukui M, Yagasaki T, Yokoyama Y
Jpn J Ophthalmol 2022 Jan;66(1):81-86. Epub 2021 Oct 19 doi: 10.1007/s10384-021-00881-1. PMID: 34665373
Dose-Response of Primary Bilateral Medial Rectus Resection in Infantile Exotropia.
Farias LB, Barham R, Costa AL, Wang S, Weakley DR Jr
J Pediatr Ophthalmol Strabismus 2022 Jan-Feb;59(1):24-27. Epub 2021 Aug 26 doi: 10.3928/01913913-20210706-02. PMID: 34435908
Motor and Sensory Outcomes of Infantile Exotropia: A 10-Year Study (2008-2017).
Rajavi Z, Sabbaghi H, Behradfar N, Abdi S, Bahraini R, Kheiri B, Sheibani K
Korean J Ophthalmol 2020 Apr;34(2):143-149. doi: 10.3341/kjo.2019.0090. PMID: 32233148Free PMC Article
The Effect of Preoperative Occlusion Therapy on Long-term Outcome after Surgery for Early-onset Exotropia.
Shin KH, Kim IN, Paik HJ
Korean J Ophthalmol 2017 Jun;31(3):268-274. Epub 2017 May 11 doi: 10.3341/kjo.2015.0168. PMID: 28534342Free PMC Article
Comparison of Clinical Features and Long-term Surgical Outcomes in Infantile Constant and Intermittent Exotropia.
Na KH, Kim SH
J Pediatr Ophthalmol Strabismus 2016 Mar-Apr;53(2):99-104. Epub 2016 Feb 4 doi: 10.3928/01913913-20160122-05. PMID: 26848593

Clinical prediction guides

Long-term Motor and Sensory Outcomes After Unilateral Medial Rectus Recession-Lateral Rectus Resection for Infantile Esotropia.
Mohan K, Sharma SK
J Pediatr Ophthalmol Strabismus 2024 Mar-Apr;61(2):106-113. Epub 2023 Aug 24 doi: 10.3928/01913913-20230721-01. PMID: 37615418
Motor and Sensory Outcomes of Infantile Exotropia: A 10-Year Study (2008-2017).
Rajavi Z, Sabbaghi H, Behradfar N, Abdi S, Bahraini R, Kheiri B, Sheibani K
Korean J Ophthalmol 2020 Apr;34(2):143-149. doi: 10.3341/kjo.2019.0090. PMID: 32233148Free PMC Article
Everyday Exotropia: Learning from the Littlest.
Petrunak JL
Am Orthopt J 2017 Jan;67(1):52-60. doi: 10.3368/aoj.67.1.52. PMID: 28904215
Comparison of Clinical Features and Long-term Surgical Outcomes in Infantile Constant and Intermittent Exotropia.
Na KH, Kim SH
J Pediatr Ophthalmol Strabismus 2016 Mar-Apr;53(2):99-104. Epub 2016 Feb 4 doi: 10.3928/01913913-20160122-05. PMID: 26848593
Prevalence of systemic and ocular disease in infantile exotropia: comparison with infantile esotropia.
Hunter DG, Ellis FJ
Ophthalmology 1999 Oct;106(10):1951-6. doi: 10.1016/S0161-6420(99)90407-4. PMID: 10519591

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