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Respiratory and Thoracic Disorder

MedGen UID:
167267
•Concept ID:
C0851355
•
Disease or Syndrome
Synonyms: Respiratory and Thoracic Disease; Respiratory, Thoracic, and Mediastinal Disease; Respiratory, Thoracic, and Mediastinal Disorder

Definition

A non-neoplastic or neoplastic disorder that affects the respiratory system or the thoracic organs. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRespiratory and Thoracic Disorder

Professional guidelines

PubMed

ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia.
Martin-Loeches I, Torres A, Nagavci B, Aliberti S, Antonelli M, Bassetti M, Bos LD, Chalmers JD, Derde L, de Waele J, Garnacho-Montero J, Kollef M, Luna CM, Menendez R, Niederman MS, Ponomarev D, Restrepo MI, Rigau D, Schultz MJ, Weiss E, Welte T, Wunderink R
Intensive Care Med 2023 Jun;49(6):615-632. Epub 2023 Apr 4 doi: 10.1007/s00134-023-07033-8. PMID: 37012484Free PMC Article
Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline.
Raghu G, Remy-Jardin M, Richeldi L, Thomson CC, Inoue Y, Johkoh T, Kreuter M, Lynch DA, Maher TM, Martinez FJ, Molina-Molina M, Myers JL, Nicholson AG, Ryerson CJ, Strek ME, Troy LK, Wijsenbeek M, Mammen MJ, Hossain T, Bissell BD, Herman DD, Hon SM, Kheir F, Khor YH, Macrea M, Antoniou KM, Bouros D, Buendia-Roldan I, Caro F, Crestani B, Ho L, Morisset J, Olson AL, Podolanczuk A, Poletti V, Selman M, Ewing T, Jones S, Knight SL, Ghazipura M, Wilson KC
Am J Respir Crit Care Med 2022 May 1;205(9):e18-e47. doi: 10.1164/rccm.202202-0399ST. PMID: 35486072Free PMC Article
Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society.
Kalil AC, Metersky ML, Klompas M, Muscedere J, Sweeney DA, Palmer LB, Napolitano LM, O'Grady NP, Bartlett JG, Carratalà J, El Solh AA, Ewig S, Fey PD, File TM Jr, Restrepo MI, Roberts JA, Waterer GW, Cruse P, Knight SL, Brozek JL
Clin Infect Dis 2016 Sep 1;63(5):e61-e111. Epub 2016 Jul 14 doi: 10.1093/cid/ciw353. PMID: 27418577Free PMC Article

Recent clinical studies

Etiology

Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study.
Tang R, Liang H, Guo Y, Li Z, Liu Z, Lin X, Yan Z, Liu J, Xu X, Shao W, Li S, Liang W, Wang W, Cui F, He H, Yang C, Jiang L, Wang H, Chen H, Guo C, Zhang H, Gao Z, He Y, Chen X, Zhao L, Yu H, Hu J, Zhao J, Li B, Yin C, Mao W, Lin W, Xie Y, Liu J, Li X, Wu D, Hou Q, Chen Y, Chen D, Xue Y, Liang Y, Tang W, Wang Q, Li E, Liu H, Wang G, Yu P, Chen C, Zheng B, Chen H, Zhang Z, Wang L, Wang A, Li Z, Fu J, Zhang G, Zhang J, Liu B, Zhao J, Deng B, Han Y, Leng X, Li Z, Zhang M, Liu C, Wang T, Luo Z, Yang C, Guo X, Ma K, Wang L, Jiang W, Han X, Wang Q, Qiao K, Xia Z, Zheng S, Xu C, Peng J, Wu S, Zhang Z, Huang H, Pang D, Liu Q, Li J, Ding X, Liu X, Zhong L, Lu Y, Xu F, Dai Q, He J
Lancet Digit Health 2023 Sep;5(9):e560-e570. doi: 10.1016/S2589-7500(23)00106-1. PMID: 37625894
Clinical and biochemical footprints of inherited metabolic diseases. XIII. Respiratory manifestations.
Rossi A, Basilicata S, Borrelli M, Ferreira CR, Blau N, Santamaria F
Mol Genet Metab 2023 Nov;140(3):107655. Epub 2023 Jul 24 doi: 10.1016/j.ymgme.2023.107655. PMID: 37517329
Transbronchial needle aspiration combined with cryobiopsy in the diagnosis of mediastinal diseases: a multicentre, open-label, randomised trial.
Fan Y, Zhang AM, Wu XL, Huang ZS, Kontogianni K, Sun K, Fu WL, Wu N, Kuebler WM, Herth FJF
Lancet Respir Med 2023 Mar;11(3):256-264. Epub 2022 Oct 22 doi: 10.1016/S2213-2600(22)00392-7. PMID: 36279880
Anesthesia for children with anterior mediastinal masses.
Tan A, Nolan JA
Paediatr Anaesth 2022 Jan;32(1):4-9. Epub 2021 Nov 14 doi: 10.1111/pan.14319. PMID: 34714957
Preoperative cardiac and respiratory investigations do not predict cardio-respiratory complications after pancreatectomy.
Ashrafizadeh A, Mehta S, Nahm CB, Doane M, Samra JS, Mittal A
ANZ J Surg 2020 Jan;90(1-2):97-102. Epub 2019 Oct 17 doi: 10.1111/ans.15515. PMID: 31625268

Diagnosis

Thoracic Applications of Spectral CT Scan.
Moore J, Remy J, Altschul E, Chusid J, Flohr T, Raoof S, Remy-Jardin M
Chest 2024 Feb;165(2):417-430. Epub 2023 Aug 22 doi: 10.1016/j.chest.2023.07.4225. PMID: 37619663
Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study.
Tang R, Liang H, Guo Y, Li Z, Liu Z, Lin X, Yan Z, Liu J, Xu X, Shao W, Li S, Liang W, Wang W, Cui F, He H, Yang C, Jiang L, Wang H, Chen H, Guo C, Zhang H, Gao Z, He Y, Chen X, Zhao L, Yu H, Hu J, Zhao J, Li B, Yin C, Mao W, Lin W, Xie Y, Liu J, Li X, Wu D, Hou Q, Chen Y, Chen D, Xue Y, Liang Y, Tang W, Wang Q, Li E, Liu H, Wang G, Yu P, Chen C, Zheng B, Chen H, Zhang Z, Wang L, Wang A, Li Z, Fu J, Zhang G, Zhang J, Liu B, Zhao J, Deng B, Han Y, Leng X, Li Z, Zhang M, Liu C, Wang T, Luo Z, Yang C, Guo X, Ma K, Wang L, Jiang W, Han X, Wang Q, Qiao K, Xia Z, Zheng S, Xu C, Peng J, Wu S, Zhang Z, Huang H, Pang D, Liu Q, Li J, Ding X, Liu X, Zhong L, Lu Y, Xu F, Dai Q, He J
Lancet Digit Health 2023 Sep;5(9):e560-e570. doi: 10.1016/S2589-7500(23)00106-1. PMID: 37625894
Thoracic Insufficiency Syndrome.
Mayer O, Campbell R, Cahill P, Redding G
Curr Probl Pediatr Adolesc Health Care 2016 Mar;46(3):72-97. Epub 2015 Dec 30 doi: 10.1016/j.cppeds.2015.11.001. PMID: 26747620
Thoracic imaging.
Hansell DM, Boiselle PM, Goldin J, Kauczor HU, Lynch DA, Mayo JR, Patz EF Jr
Respirology 2010 Apr;15(3):393-400. Epub 2010 Jan 28 doi: 10.1111/j.1440-1843.2009.01698.x. PMID: 20136737
Respiratory muscle failure.
Rochester DF, Arora NS
Med Clin North Am 1983 May;67(3):573-97. doi: 10.1016/s0025-7125(16)31190-7. PMID: 6341727

Therapy

Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trial.
Kjellberg A, Abdel-Halim L, Hassler A, El Gharbi S, Al-Ezerjawi S, Boström E, Sundberg CJ, Pernow J, Medson K, Kowalski JH, Rodriguez-Wallberg KA, Zheng X, Catrina S, Runold M, Ståhlberg M, Bruchfeld J, Nygren-Bonnier M, Lindholm P
BMJ Open 2022 Nov 2;12(11):e061870. doi: 10.1136/bmjopen-2022-061870. PMID: 36323462Free PMC Article
Pulmonary Alveolar Microlithiasis.
Shaw BM, Shaw SD, McCormack FX
Semin Respir Crit Care Med 2020 Apr;41(2):280-287. Epub 2020 Apr 12 doi: 10.1055/s-0040-1702211. PMID: 32279298
Lung cancer staging: a concise update.
Rami-Porta R, Call S, Dooms C, Obiols C, Sánchez M, Travis WD, Vollmer I
Eur Respir J 2018 May;51(5) Epub 2018 May 17 doi: 10.1183/13993003.00190-2018. PMID: 29700105
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT).
Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H, Kollef M, Li Bassi G, Luna CM, Martin-Loeches I, Paiva JA, Read RC, Rigau D, Timsit JF, Welte T, Wunderink R
Eur Respir J 2017 Sep;50(3) Epub 2017 Sep 10 doi: 10.1183/13993003.00582-2017. PMID: 28890434
European Respiratory Society guidelines for the management of adult bronchiectasis.
Polverino E, Goeminne PC, McDonnell MJ, Aliberti S, Marshall SE, Loebinger MR, Murris M, Cantón R, Torres A, Dimakou K, De Soyza A, Hill AT, Haworth CS, Vendrell M, Ringshausen FC, Subotic D, Wilson R, Vilaró J, Stallberg B, Welte T, Rohde G, Blasi F, Elborn S, Almagro M, Timothy A, Ruddy T, Tonia T, Rigau D, Chalmers JD
Eur Respir J 2017 Sep;50(3) Epub 2017 Sep 9 doi: 10.1183/13993003.00629-2017. PMID: 28889110

Prognosis

Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study.
Tang R, Liang H, Guo Y, Li Z, Liu Z, Lin X, Yan Z, Liu J, Xu X, Shao W, Li S, Liang W, Wang W, Cui F, He H, Yang C, Jiang L, Wang H, Chen H, Guo C, Zhang H, Gao Z, He Y, Chen X, Zhao L, Yu H, Hu J, Zhao J, Li B, Yin C, Mao W, Lin W, Xie Y, Liu J, Li X, Wu D, Hou Q, Chen Y, Chen D, Xue Y, Liang Y, Tang W, Wang Q, Li E, Liu H, Wang G, Yu P, Chen C, Zheng B, Chen H, Zhang Z, Wang L, Wang A, Li Z, Fu J, Zhang G, Zhang J, Liu B, Zhao J, Deng B, Han Y, Leng X, Li Z, Zhang M, Liu C, Wang T, Luo Z, Yang C, Guo X, Ma K, Wang L, Jiang W, Han X, Wang Q, Qiao K, Xia Z, Zheng S, Xu C, Peng J, Wu S, Zhang Z, Huang H, Pang D, Liu Q, Li J, Ding X, Liu X, Zhong L, Lu Y, Xu F, Dai Q, He J
Lancet Digit Health 2023 Sep;5(9):e560-e570. doi: 10.1016/S2589-7500(23)00106-1. PMID: 37625894
COVID-19-Related Pleural Diseases.
Iqbal B, Rahman NM, Hallifax RJ
Semin Respir Crit Care Med 2023 Aug;44(4):437-446. Epub 2023 Jul 10 doi: 10.1055/s-0043-1769616. PMID: 37429295
Pediatric pneumomediastinum: Symptom-based management.
Dougherty D, Meyer KM, Thompson AR, Speck KE
J Pediatr Surg 2023 Mar;58(3):427-431. Epub 2022 Oct 21 doi: 10.1016/j.jpedsurg.2022.10.016. PMID: 36460493
Anesthesia for children with anterior mediastinal masses.
Tan A, Nolan JA
Paediatr Anaesth 2022 Jan;32(1):4-9. Epub 2021 Nov 14 doi: 10.1111/pan.14319. PMID: 34714957
Pulmonary Function Testing in Neuromuscular and Chest Wall Disorders.
Gartman EJ
Clin Chest Med 2018 Jun;39(2):325-334. doi: 10.1016/j.ccm.2018.01.005. PMID: 29779592

Clinical prediction guides

Pan-mediastinal neoplasm diagnosis via nationwide federated learning: a multicentre cohort study.
Tang R, Liang H, Guo Y, Li Z, Liu Z, Lin X, Yan Z, Liu J, Xu X, Shao W, Li S, Liang W, Wang W, Cui F, He H, Yang C, Jiang L, Wang H, Chen H, Guo C, Zhang H, Gao Z, He Y, Chen X, Zhao L, Yu H, Hu J, Zhao J, Li B, Yin C, Mao W, Lin W, Xie Y, Liu J, Li X, Wu D, Hou Q, Chen Y, Chen D, Xue Y, Liang Y, Tang W, Wang Q, Li E, Liu H, Wang G, Yu P, Chen C, Zheng B, Chen H, Zhang Z, Wang L, Wang A, Li Z, Fu J, Zhang G, Zhang J, Liu B, Zhao J, Deng B, Han Y, Leng X, Li Z, Zhang M, Liu C, Wang T, Luo Z, Yang C, Guo X, Ma K, Wang L, Jiang W, Han X, Wang Q, Qiao K, Xia Z, Zheng S, Xu C, Peng J, Wu S, Zhang Z, Huang H, Pang D, Liu Q, Li J, Ding X, Liu X, Zhong L, Lu Y, Xu F, Dai Q, He J
Lancet Digit Health 2023 Sep;5(9):e560-e570. doi: 10.1016/S2589-7500(23)00106-1. PMID: 37625894
A score for predicting invasive pulmonary aspergillosis in immunocompetent critically ill patients.
Li W, Chen G, Lin F, Yang H, Cui Y, Lu R, Song C, Li H, Li Y, Pan P
Eur J Clin Invest 2023 Jul;53(7):e13985. Epub 2023 Mar 24 doi: 10.1111/eci.13985. PMID: 36920323
Incidence and Clinical Features of Pneumomediastinum and Pneumothorax in COVID-19 Pneumonia.
Muhammad AI, Mehta M, Shaw M, Hussain N, Joseph S, Vancheeswaran R
J Intensive Care Med 2022 Aug;37(8):1015-1018. Epub 2022 Mar 31 doi: 10.1177/08850666221091441. PMID: 35360973Free PMC Article
Lung ultrasound in bronchiolitis.
La Regina DP, Bloise S, Pepino D, Iovine E, Laudisa M, Cristiani L, Nicolai A, Nenna R, Mancino E, Di Mattia G, Petrarca L, Matera L, Frassanito A, Midulla F
Pediatr Pulmonol 2021 Jan;56(1):234-239. Epub 2020 Nov 24 doi: 10.1002/ppul.25156. PMID: 33151023
Overlaps and uncertainties of smoking-related idiopathic interstitial pneumonias.
Bak SH, Lee HY
Int J Chron Obstruct Pulmon Dis 2017;12:3221-3229. Epub 2017 Nov 1 doi: 10.2147/COPD.S146899. PMID: 29138550Free PMC Article

Recent systematic reviews

ARDS clinical practice guideline 2021.
Tasaka S, Ohshimo S, Takeuchi M, Yasuda H, Ichikado K, Tsushima K, Egi M, Hashimoto S, Shime N, Saito O, Matsumoto S, Nango E, Okada Y, Hayashi K, Sakuraya M, Nakajima M, Okamori S, Miura S, Fukuda T, Ishihara T, Kamo T, Yatabe T, Norisue Y, Aoki Y, Iizuka Y, Kondo Y, Narita C, Kawakami D, Okano H, Takeshita J, Anan K, Okazaki SR, Taito S, Hayashi T, Mayumi T, Terayama T, Kubota Y, Abe Y, Iwasaki Y, Kishihara Y, Kataoka J, Nishimura T, Yonekura H, Ando K, Yoshida T, Masuyama T, Sanui M; ARDS Clinical Practice Guideline Committee 2021 from the Japanese Respiratory Society, the Japanese Society of Intensive Care Medicine, and the Japanese Society of Respiratory Care Medicine
Respir Investig 2022 Jul;60(4):446-495. Epub 2022 Jun 24 doi: 10.1016/j.resinv.2022.05.003. PMID: 35753956
Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review.
Uyttebroek S, Chen B, Onsea J, Ruythooren F, Debaveye Y, Devolder D, Spriet I, Depypere M, Wagemans J, Lavigne R, Pirnay JP, Merabishvili M, De Munter P, Peetermans WE, Dupont L, Van Gerven L, Metsemakers WJ
Lancet Infect Dis 2022 Aug;22(8):e208-e220. Epub 2022 Mar 3 doi: 10.1016/S1473-3099(21)00612-5. PMID: 35248167
The effectiveness of the active cycle of breathing technique in patients with chronic respiratory diseases: A systematic review.
Zisi D, Chryssanthopoulos C, Nanas S, Philippou A
Heart Lung 2022 May-Jun;53:89-98. Epub 2022 Feb 27 doi: 10.1016/j.hrtlng.2022.02.006. PMID: 35235877
2020 guide for the diagnosis and treatment of interstitial lung disease associated with connective tissue disease.
Kondoh Y, Makino S, Ogura T, Suda T, Tomioka H, Amano H, Anraku M, Enomoto N, Fujii T, Fujisawa T, Gono T, Harigai M, Ichiyasu H, Inoue Y, Johkoh T, Kameda H, Kataoka K, Katsumata Y, Kawaguchi Y, Kawakami A, Kitamura H, Kitamura N, Koga T, Kurasawa K, Nakamura Y, Nakashima R, Nishioka Y, Nishiyama O, Okamoto M, Sakai F, Sakamoto S, Sato S, Shimizu T, Takayanagi N, Takei R, Takemura T, Takeuchi T, Toyoda Y, Yamada H, Yamakawa H, Yamano Y, Yamasaki Y, Kuwana M; joint committee of Japanese Respiratory Society and Japan College of Rheumatology
Respir Investig 2021 Nov;59(6):709-740. Epub 2021 Oct 1 doi: 10.1016/j.resinv.2021.04.011. PMID: 34602377
An official European Respiratory Society/American Thoracic Society technical standard: field walking tests in chronic respiratory disease.
Holland AE, Spruit MA, Troosters T, Puhan MA, Pepin V, Saey D, McCormack MC, Carlin BW, Sciurba FC, Pitta F, Wanger J, MacIntyre N, Kaminsky DA, Culver BH, Revill SM, Hernandes NA, Andrianopoulos V, Camillo CA, Mitchell KE, Lee AL, Hill CJ, Singh SJ
Eur Respir J 2014 Dec;44(6):1428-46. Epub 2014 Oct 30 doi: 10.1183/09031936.00150314. PMID: 25359355

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    Practice guidelines

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