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Recurrent Paraganglioma

MedGen UID:
1673963
•Concept ID:
C4763424
•
Neoplastic Process

Definition

The reemergence of paraganglioma after a period of remission. [from NCI]

Professional guidelines

PubMed

The diagnosis and management of pheochromocytoma and paraganglioma during pregnancy.
Clifton-Bligh RJ
Rev Endocr Metab Disord 2023 Feb;24(1):49-56. Epub 2023 Jan 13 doi: 10.1007/s11154-022-09773-2. PMID: 36637675Free PMC Article
Personalized Management of Pheochromocytoma and Paraganglioma.
Nölting S, Bechmann N, Taieb D, Beuschlein F, Fassnacht M, Kroiss M, Eisenhofer G, Grossman A, Pacak K
Endocr Rev 2022 Mar 9;43(2):199-239. doi: 10.1210/endrev/bnab019. PMID: 34147030Free PMC Article
Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.
Lenders JW, Duh QY, Eisenhofer G, Gimenez-Roqueplo AP, Grebe SK, Murad MH, Naruse M, Pacak K, Young WF Jr; Endocrine Society
J Clin Endocrinol Metab 2014 Jun;99(6):1915-42. doi: 10.1210/jc.2014-1498. PMID: 24893135

Recent clinical studies

Etiology

Reduced Risk of Corporal Tumors in Patients With Head and Neck Paragangliomas With p.Pro81Leu Mutations.
Miller KM, Sbeih F, Contrera K, Reddy CA, Marquard J, Eng C, Lorenz RR
Otolaryngol Head Neck Surg 2023 Sep;169(3):570-576. Epub 2023 Feb 7 doi: 10.1002/ohn.274. PMID: 36939592
Comparison of 123I-MIBG SPECT-CT and 18F-DOPA PET-CT in the evaluation of patients with known or suspected recurrent paraganglioma.
Rufini V, Treglia G, Castaldi P, Perotti G, Calcagni ML, Corsello SM, Galli G, Fanti S, Giordano A
Nucl Med Commun 2011 Jul;32(7):575-82. doi: 10.1097/MNM.0b013e328345a340. PMID: 21471850
Clinical value of somatostatin receptor imaging in patients with suspected head and neck paragangliomas.
Schmidt M, Fischer E, Dietlein M, Michel O, Weber K, Moka D, Stennert E, Schicha H
Eur J Nucl Med Mol Imaging 2002 Dec;29(12):1571-80. Epub 2002 Sep 21 doi: 10.1007/s00259-002-0939-6. PMID: 12458390
Paragangliomas-- a decade of clinical experience.
Somasundar P, Krouse R, Hostetter R, Vaughan R, Covey T
J Surg Oncol 2000 Aug;74(4):286-90. doi: 10.1002/1096-9098(200008)74:4<286::aid-jso9>3.0.co;2-c. PMID: 10962462
Extra-adrenal paragangliomas of the retroperitoneum: A clinicopathologic study of 12 tumors.
Lack EE, Cubilla AL, Woodruff JM, Lieberman PH
Am J Surg Pathol 1980 Apr;4(2):109-20. doi: 10.1097/00000478-198004000-00002. PMID: 7377461

Diagnosis

Management of a Complex Case of a Recurrent Paraganglioma.
Petrovic M, Borrelli M, Shohet JA
Ear Nose Throat J 2023 Sep;102(9_suppl):20S-23S. Epub 2023 Aug 8 doi: 10.1177/01455613231187762. PMID: 37551648
Arterial thrombosis and intracardiac thrombus as the initial presentation of a recurrent paraganglioma: case report and review of the literature.
Quintanilla-Flores DL, Villarreal-Pérez JZ, Vélez-Viveros CA, Portillo-Sánchez P, Ortíz-Morales AJ, González-González JG
Arch Endocrinol Metab 2021 Nov 24;65(6):852-857. Epub 2021 Mar 19 doi: 10.20945/2359-3997000000342. PMID: 33740338Free PMC Article
Comparison of 123I-MIBG SPECT-CT and 18F-DOPA PET-CT in the evaluation of patients with known or suspected recurrent paraganglioma.
Rufini V, Treglia G, Castaldi P, Perotti G, Calcagni ML, Corsello SM, Galli G, Fanti S, Giordano A
Nucl Med Commun 2011 Jul;32(7):575-82. doi: 10.1097/MNM.0b013e328345a340. PMID: 21471850
Clinical value of somatostatin receptor imaging in patients with suspected head and neck paragangliomas.
Schmidt M, Fischer E, Dietlein M, Michel O, Weber K, Moka D, Stennert E, Schicha H
Eur J Nucl Med Mol Imaging 2002 Dec;29(12):1571-80. Epub 2002 Sep 21 doi: 10.1007/s00259-002-0939-6. PMID: 12458390
Paragangliomas-- a decade of clinical experience.
Somasundar P, Krouse R, Hostetter R, Vaughan R, Covey T
J Surg Oncol 2000 Aug;74(4):286-90. doi: 10.1002/1096-9098(200008)74:4<286::aid-jso9>3.0.co;2-c. PMID: 10962462

Therapy

Resection of a recurrent paraganglioma via an endoscopic transnasal approach to the jugular fossa.
Zimmer LA, Hirsch BE, Kassam A, Horowitz M, Snyderman CH
Otol Neurotol 2006 Apr;27(3):398-402. doi: 10.1097/00129492-200604000-00017. PMID: 16639280
PET scan assessment of chemotherapy response in metastatic paraganglioma.
Argiris A, Mellott A, Spies S
Am J Clin Oncol 2003 Dec;26(6):563-6. doi: 10.1097/01.coc.0000037765.75950.3A. PMID: 14663372
Clinical value of somatostatin receptor imaging in patients with suspected head and neck paragangliomas.
Schmidt M, Fischer E, Dietlein M, Michel O, Weber K, Moka D, Stennert E, Schicha H
Eur J Nucl Med Mol Imaging 2002 Dec;29(12):1571-80. Epub 2002 Sep 21 doi: 10.1007/s00259-002-0939-6. PMID: 12458390

Prognosis

Clinical value of somatostatin receptor imaging in patients with suspected head and neck paragangliomas.
Schmidt M, Fischer E, Dietlein M, Michel O, Weber K, Moka D, Stennert E, Schicha H
Eur J Nucl Med Mol Imaging 2002 Dec;29(12):1571-80. Epub 2002 Sep 21 doi: 10.1007/s00259-002-0939-6. PMID: 12458390
Paragangliomas-- a decade of clinical experience.
Somasundar P, Krouse R, Hostetter R, Vaughan R, Covey T
J Surg Oncol 2000 Aug;74(4):286-90. doi: 10.1002/1096-9098(200008)74:4<286::aid-jso9>3.0.co;2-c. PMID: 10962462
Extra-adrenal paragangliomas of the retroperitoneum: A clinicopathologic study of 12 tumors.
Lack EE, Cubilla AL, Woodruff JM, Lieberman PH
Am J Surg Pathol 1980 Apr;4(2):109-20. doi: 10.1097/00000478-198004000-00002. PMID: 7377461

Clinical prediction guides

Management of a Complex Case of a Recurrent Paraganglioma.
Petrovic M, Borrelli M, Shohet JA
Ear Nose Throat J 2023 Sep;102(9_suppl):20S-23S. Epub 2023 Aug 8 doi: 10.1177/01455613231187762. PMID: 37551648
Managing the Unmanageable: A Two-Staged Palliative Resection to Control Life-Threatening Duodenal Bleeding Due to Recurrent Paraganglioma.
Smucker LY, Hardy AN, O'Neil PJ, Schwarz RE
Am J Case Rep 2018 Apr 2;19:386-391. doi: 10.12659/ajcr.907760. PMID: 29606699Free PMC Article
Clinical value of somatostatin receptor imaging in patients with suspected head and neck paragangliomas.
Schmidt M, Fischer E, Dietlein M, Michel O, Weber K, Moka D, Stennert E, Schicha H
Eur J Nucl Med Mol Imaging 2002 Dec;29(12):1571-80. Epub 2002 Sep 21 doi: 10.1007/s00259-002-0939-6. PMID: 12458390

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