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Tumors are benign

MedGen UID:
1676714
•Concept ID:
C5195477
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTumors are benign

Professional guidelines

PubMed

The Future of Uterine Fibroid Management: a More Preventive and Personalized Paradigm.
El Sabeh M, Borahay MA
Reprod Sci 2021 Nov;28(11):3285-3288. Epub 2021 May 18 doi: 10.1007/s43032-021-00618-y. PMID: 34008153Free PMC Article
Relugolix for the treatment of uterine fibroids.
Rocca ML, Palumbo AR, Lico D, Fiorenza A, Bitonti G, D'Agostino S, Gallo C, Di Carlo C, Zullo F, Venturella R
Expert Opin Pharmacother 2020 Oct;21(14):1667-1674. Epub 2020 Jul 17 doi: 10.1080/14656566.2020.1787988. PMID: 32674616
Pheochromocytoma and Paraganglioma: Genetics, Diagnosis, and Treatment.
Fishbein L
Hematol Oncol Clin North Am 2016 Feb;30(1):135-50. Epub 2015 Oct 23 doi: 10.1016/j.hoc.2015.09.006. PMID: 26614373

Recent clinical studies

Etiology

Primary Benign Tumors of the Spinal Canal.
Carlos-Escalante JA, Paz-López ÁA, Cacho-Díaz B, Pacheco-Cuellar G, Reyes-Soto G, Wegman-Ostrosky T
World Neurosurg 2022 Aug;164:178-198. Epub 2022 May 10 doi: 10.1016/j.wneu.2022.04.135. PMID: 35552036
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Diagnostic Pathology of Tumors of Peripheral Nerve.
Belakhoua SM, Rodriguez FJ
Neurosurgery 2021 Feb 16;88(3):443-456. doi: 10.1093/neuros/nyab021. PMID: 33588442Free PMC Article
ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts.
Elta GH, Enestvedt BK, Sauer BG, Lennon AM
Am J Gastroenterol 2018 Apr;113(4):464-479. Epub 2018 Feb 27 doi: 10.1038/ajg.2018.14. PMID: 29485131
Bone cysts: unicameral and aneurysmal bone cyst.
Mascard E, Gomez-Brouchet A, Lambot K
Orthop Traumatol Surg Res 2015 Feb;101(1 Suppl):S119-27. Epub 2015 Jan 8 doi: 10.1016/j.otsr.2014.06.031. PMID: 25579825

Diagnosis

Management of neurofibromatosis type 1-associated plexiform neurofibromas.
Fisher MJ, Blakeley JO, Weiss BD, Dombi E, Ahlawat S, Akshintala S, Belzberg AJ, Bornhorst M, Bredella MA, Cai W, Ferner RE, Gross AM, Harris GJ, Listernick R, Ly I, Martin S, Mautner VF, Salamon JM, Salerno KE, Spinner RJ, Staedtke V, Ullrich NJ, Upadhyaya M, Wolters PL, Yohay K, Widemann BC
Neuro Oncol 2022 Nov 2;24(11):1827-1844. doi: 10.1093/neuonc/noac146. PMID: 35657359Free PMC Article
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Nerve Tumors of the Upper Extremity.
Strike SA, Puhaindran ME
Clin Plast Surg 2019 Jul;46(3):347-350. doi: 10.1016/j.cps.2019.02.008. PMID: 31103079
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Tumors and tumor-like lesions of peripheral nerves.
Woertler K
Semin Musculoskelet Radiol 2010 Nov;14(5):547-58. Epub 2010 Nov 11 doi: 10.1055/s-0030-1268073. PMID: 21072731

Therapy

Effectiveness of different treatments for odontogenic keratocyst: a network meta-analysis.
Al-Moraissi EA, Kaur A, Gomez RS, Ellis E 3rd
Int J Oral Maxillofac Surg 2023 Jan;52(1):32-43. Epub 2022 Sep 21 doi: 10.1016/j.ijom.2022.09.004. PMID: 36150944
How effective is 5-Fluorouracil as an adjuvant in the management of odontogenic keratocyst? A systematic review and meta-analysis.
Singh AK, Khanal N, Chaulagain R, Bhujel N, Singh RP
Br J Oral Maxillofac Surg 2022 Jul;60(6):746-754. Epub 2022 Feb 17 doi: 10.1016/j.bjoms.2022.02.001. PMID: 35314081
Denosumab in the management of Aneurysmal bone cyst.
Maximen J, Robin F, Tronchot A, Rossetti A, Ropars M, Guggenbuhl P
Joint Bone Spine 2022 Jan;89(1):105260. Epub 2021 Sep 2 doi: 10.1016/j.jbspin.2021.105260. PMID: 34481945
Radiomics in stratification of pancreatic cystic lesions: Machine learning in action.
Dalal V, Carmicheal J, Dhaliwal A, Jain M, Kaur S, Batra SK
Cancer Lett 2020 Jan 28;469:228-237. Epub 2019 Oct 17 doi: 10.1016/j.canlet.2019.10.023. PMID: 31629933Free PMC Article
Neurofibromatosis type 1: a multidisciplinary approach to care.
Hirbe AC, Gutmann DH
Lancet Neurol 2014 Aug;13(8):834-43. doi: 10.1016/S1474-4422(14)70063-8. PMID: 25030515

Prognosis

Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Pancreatic Cysts.
Meagher T, Armuss A
J Insur Med 2016;46(2):60-65. doi: 10.17849/0743-6661-46.2.60. PMID: 28326875
Bone cysts: unicameral and aneurysmal bone cyst.
Mascard E, Gomez-Brouchet A, Lambot K
Orthop Traumatol Surg Res 2015 Feb;101(1 Suppl):S119-27. Epub 2015 Jan 8 doi: 10.1016/j.otsr.2014.06.031. PMID: 25579825
Neurofibromatosis type 1 (NF1) and associated tumors.
Rosenbaum T, Wimmer K
Klin Padiatr 2014 Nov;226(6-7):309-15. Epub 2014 Jul 25 doi: 10.1055/s-0034-1382021. PMID: 25062113
Benign tumors of the spine.
Thakur NA, Daniels AH, Schiller J, Valdes MA, Czerwein JK, Schiller A, Esmende S, Terek RM
J Am Acad Orthop Surg 2012 Nov;20(11):715-24. doi: 10.5435/JAAOS-20-11-715. PMID: 23118137

Clinical prediction guides

Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment.
Kershner LJ, Choi K, Wu J, Zhang X, Perrino M, Salomonis N, Shern JF, Ratner N
JCI Insight 2022 Sep 22;7(18) doi: 10.1172/jci.insight.154513. PMID: 36134665Free PMC Article
Dacryops - A review.
Tanaboonyawat S, Idowu OO, Copperman TS, Vagefi MR, Kersten RC
Orbit 2020 Apr;39(2):128-134. Epub 2019 Sep 12 doi: 10.1080/01676830.2019.1608564. PMID: 31512543
The NF1 somatic mutational landscape in sporadic human cancers.
Philpott C, Tovell H, Frayling IM, Cooper DN, Upadhyaya M
Hum Genomics 2017 Jun 21;11(1):13. doi: 10.1186/s40246-017-0109-3. PMID: 28637487Free PMC Article
Neurofibromatosis type 1 (NF1) and associated tumors.
Rosenbaum T, Wimmer K
Klin Padiatr 2014 Nov;226(6-7):309-15. Epub 2014 Jul 25 doi: 10.1055/s-0034-1382021. PMID: 25062113
Benign tumors of the spine.
Thakur NA, Daniels AH, Schiller J, Valdes MA, Czerwein JK, Schiller A, Esmende S, Terek RM
J Am Acad Orthop Surg 2012 Nov;20(11):715-24. doi: 10.5435/JAAOS-20-11-715. PMID: 23118137

Recent systematic reviews

Molecular Insights in Uterine Leiomyosarcoma: A Systematic Review.
Sparić R, Andjić M, Babović I, Nejković L, Mitrović M, Štulić J, Pupovac M, Tinelli A
Int J Mol Sci 2022 Aug 27;23(17) doi: 10.3390/ijms23179728. PMID: 36077127Free PMC Article
A Comprehensive Review of Hepatic Hemangioma Management.
Aziz H, Brown ZJ, Baghdadi A, Kamel IR, Pawlik TM
J Gastrointest Surg 2022 Sep;26(9):1998-2007. Epub 2022 Jun 15 doi: 10.1007/s11605-022-05382-1. PMID: 35705835
Malignant phyllodes tumor of the breast: a systematic review.
Lissidini G, Mulè A, Santoro A, Papa G, Nicosia L, Cassano E, Ashoor AA, Veronesi P, Pantanowitz L, Hornick JL, Rossi ED
Pathologica 2022 Apr;114(2):111-120. Epub 2022 Apr 13 doi: 10.32074/1591-951X-754. PMID: 35414723Free PMC Article
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria.
Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E
J Natl Cancer Inst 2013 Nov 6;105(21):1607-16. Epub 2013 Oct 17 doi: 10.1093/jnci/djt277. PMID: 24136893

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