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Decreased Sperm Count

MedGen UID:
167691
Concept ID:
C0853711
Finding
Synonym: Decreased sperm count

Definition

A finding indicating the presence of a lower than expected number of spermatozoa in the semen. [from NCI]

Recent clinical studies

Etiology

Gubatan J, Barber GE, Nielsen OH, Juhl CB, Maxwell C, Eisenberg ML, Streett SE
Clin Gastroenterol Hepatol 2023 Aug;21(9):2222-2238. Epub 2022 Jul 20 doi: 10.1016/j.cgh.2022.07.008. PMID: 35870769
Wang K, Gao Y, Wang C, Liu Z, Liang M, Liao Y, Hu K
DNA Cell Biol 2022 Oct;41(10):861-870. Epub 2022 Sep 2 doi: 10.1089/dna.2022.0289. PMID: 36067068
Xiao L, Wang Q, Ni H, Xu T, Zeng Q, Yu X, Wu H, Guo P, Zhang Q, Zhang X
Sci Total Environ 2022 Dec 10;851(Pt 2):158245. Epub 2022 Aug 22 doi: 10.1016/j.scitotenv.2022.158245. PMID: 36007649
Sleiman HK, de Oliveira JM, Langoni de Freitas GB
Biomed Pharmacother 2021 Aug;140:111448. Epub 2021 Jun 12 doi: 10.1016/j.biopha.2021.111448. PMID: 34130202
Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031

Diagnosis

Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031
Huang G, Zhang Q, Wu H, Wang Q, Chen Y, Guo P, Zhao Q
Environ Res 2020 Sep;188:109756. Epub 2020 Jun 3 doi: 10.1016/j.envres.2020.109756. PMID: 32531526
Bukhari SA, Ahmed MM, Anjum F, Anwar H, Naqvi SAR, Zahra T, Batool U
Pak J Pharm Sci 2018 Jul;31(4(Supplementary)):1565-1570. PMID: 30058549
Attia AM, Hassan A, Zalata A, Hagag M, Yousef KE, Mostafa T
Andrologia 2011 Dec;43(6):387-91. Epub 2011 Aug 16 doi: 10.1111/j.1439-0272.2010.01056.x. PMID: 21848911
Belker AM
Urol Clin North Am 1981 Feb;8(1):41-51. PMID: 7210353

Therapy

Gubatan J, Barber GE, Nielsen OH, Juhl CB, Maxwell C, Eisenberg ML, Streett SE
Clin Gastroenterol Hepatol 2023 Aug;21(9):2222-2238. Epub 2022 Jul 20 doi: 10.1016/j.cgh.2022.07.008. PMID: 35870769
Zhang K, Guo J, Zhu Y, Zhang R
Comput Math Methods Med 2022;2022:7174399. Epub 2022 Feb 22 doi: 10.1155/2022/7174399. PMID: 35242210Free PMC Article
Guan Q, Chen S, Wang B, Dou X, Lu Y, Liang J, Ni R, Yang C, Wang H, Baktash MB, Wu W, Wang X, Fu G, Xia Y
Ecotoxicol Environ Saf 2020 Apr 15;193:110319. Epub 2020 Feb 19 doi: 10.1016/j.ecoenv.2020.110319. PMID: 32087444
Kesari KK, Kumar S, Nirala J, Siddiqui MH, Behari J
Cell Biochem Biophys 2013 Mar;65(2):85-96. doi: 10.1007/s12013-012-9414-6. PMID: 22926544
Lerchbaum E, Obermayer-Pietsch B
Eur J Endocrinol 2012 May;166(5):765-78. Epub 2012 Jan 24 doi: 10.1530/EJE-11-0984. PMID: 22275473

Prognosis

Liu M, Yang Y, Wang Y, Chen S, Shen Y
Hum Mol Genet 2022 Mar 31;31(7):1013-1021. doi: 10.1093/hmg/ddab242. PMID: 34448846Free PMC Article
Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031
Ge SQ, Grifin J, Liu LH, Aston KI, Simon L, Jenkins TG, Emery BR, Carrell DT
Genet Mol Res 2015 Aug 7;14(3):9053-61. doi: 10.4238/2015.August.7.14. PMID: 26345837
Niederberger C
J Urol 2005 Nov;174(5):1943. doi: 10.1016/s0022-5347(01)68856-6. PMID: 16217360
Hashimoto J, Nagai T, Takaba H, Yamamoto M, Miyake K
Urol Int 1988;43(3):129-32. doi: 10.1159/000281324. PMID: 3176198

Clinical prediction guides

Li Y, Zhang J, Sun L, Zhao H, Jia X, Zhang Y, Li Y
Biol Trace Elem Res 2023 Jan;201(1):295-305. Epub 2022 Feb 28 doi: 10.1007/s12011-022-03138-1. PMID: 35226278
Xiao L, Wang Q, Ni H, Xu T, Zeng Q, Yu X, Wu H, Guo P, Zhang Q, Zhang X
Sci Total Environ 2022 Dec 10;851(Pt 2):158245. Epub 2022 Aug 22 doi: 10.1016/j.scitotenv.2022.158245. PMID: 36007649
Janiszewska E, Kokot I, Gilowska I, Faundez R, Kratz EM
Sci Rep 2021 Aug 2;11(1):15674. doi: 10.1038/s41598-021-95288-w. PMID: 34341430Free PMC Article
Jiao SY, Yang YH, Chen SR
Hum Reprod Update 2021 Jan 4;27(1):154-189. doi: 10.1093/humupd/dmaa034. PMID: 33118031
Guan Q, Chen S, Wang B, Dou X, Lu Y, Liang J, Ni R, Yang C, Wang H, Baktash MB, Wu W, Wang X, Fu G, Xia Y
Ecotoxicol Environ Saf 2020 Apr 15;193:110319. Epub 2020 Feb 19 doi: 10.1016/j.ecoenv.2020.110319. PMID: 32087444

Recent systematic reviews

Gubatan J, Barber GE, Nielsen OH, Juhl CB, Maxwell C, Eisenberg ML, Streett SE
Clin Gastroenterol Hepatol 2023 Aug;21(9):2222-2238. Epub 2022 Jul 20 doi: 10.1016/j.cgh.2022.07.008. PMID: 35870769
Lerchbaum E, Obermayer-Pietsch B
Eur J Endocrinol 2012 May;166(5):765-78. Epub 2012 Jan 24 doi: 10.1530/EJE-11-0984. PMID: 22275473

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