U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Anomalous Left Coronary Artery

MedGen UID:
1676988
•Concept ID:
C5197884
•
Congenital Abnormality

Definition

Malformations of left CORONARY ARTERY where it is connected to the PULMONARY ARTERY instead of the AORTA. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnomalous Left Coronary Artery

Professional guidelines

PubMed

Diagnosis and Management of Anomalous Left Anterior Descending Coronary Artery from the Pulmonary Artery in an Asymptomatic Infant.
Gupta A, Husain N, Tannous P, Hauck A
Pediatr Cardiol 2020 Jan;41(1):209-212. Epub 2019 Sep 14 doi: 10.1007/s00246-019-02192-2. PMID: 31522266
Echocardiographic Diagnosis, Surgical Treatment, and Outcomes of Anomalous Left Coronary Artery from the Pulmonary Artery.
Patel SG, Frommelt MA, Frommelt PC, Kutty S, Cramer JW
J Am Soc Echocardiogr 2017 Sep;30(9):896-903. Epub 2017 Jun 23 doi: 10.1016/j.echo.2017.05.005. PMID: 28651802
Very early correction of anomalous left coronary artery from the pulmonary artery improves intensive care management.
Bonnemains L, Lambert V, Moulin-Zinch A, Youssef D, Serraf A
Arch Cardiovasc Dis 2010 Nov-Dec;103(11-12):579-84. Epub 2010 Nov 25 doi: 10.1016/j.acvd.2010.10.005. PMID: 21147442

Recent clinical studies

Etiology

Intramural course of an anomalous left coronary artery is not always associated with a slit-like ostium.
Montaña-Jimenez LP, Molossi S, Masand P, Heinle JS, Binsalamah Z, Doan TT
Cardiol Young 2023 Apr;33(4):627-629. Epub 2023 Jan 17 doi: 10.1017/S104795112300001X. PMID: 36647704
Introduction to anomalous aortic origin of a coronary artery.
Brothers JA
Congenit Heart Dis 2017 Sep;12(5):600-602. Epub 2017 Jun 27 doi: 10.1111/chd.12497. PMID: 28653465
Anomalous Aortic Origin of a Coronary Artery From the Inappropriate Sinus of Valsalva.
Cheezum MK, Liberthson RR, Shah NR, Villines TC, O'Gara PT, Landzberg MJ, Blankstein R
J Am Coll Cardiol 2017 Mar 28;69(12):1592-1608. doi: 10.1016/j.jacc.2017.01.031. PMID: 28335843
Coronary artery anomalies in children: what is the risk?
Brothers JA
Curr Opin Pediatr 2016 Oct;28(5):590-6. doi: 10.1097/MOP.0000000000000399. PMID: 27379803
Anomalous Aortic Origin of a Coronary Artery is Always a Surgical Disease.
Vouhé PR
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2016;19(1):25-9. doi: 10.1053/j.pcsu.2015.12.007. PMID: 27060039

Diagnosis

Intramural course of an anomalous left coronary artery is not always associated with a slit-like ostium.
Montaña-Jimenez LP, Molossi S, Masand P, Heinle JS, Binsalamah Z, Doan TT
Cardiol Young 2023 Apr;33(4):627-629. Epub 2023 Jan 17 doi: 10.1017/S104795112300001X. PMID: 36647704
Anomalous origins of the coronary arteries: current knowledge and future perspectives.
Mazine A, Fernandes IM, Haller C, Hickey EJ
Curr Opin Cardiol 2019 Sep;34(5):543-551. doi: 10.1097/HCO.0000000000000663. PMID: 31335330
Introduction to anomalous aortic origin of a coronary artery.
Brothers JA
Congenit Heart Dis 2017 Sep;12(5):600-602. Epub 2017 Jun 27 doi: 10.1111/chd.12497. PMID: 28653465
Paediatric-onset coronary artery anomalies in pregnancy: a single-centre experience and systematic literature review.
Keir M, Bhagra C, Vatenmakher D, Arancibia-Galilea F, Jansen K, Toh N, Silversides CK, Colman J, Siu SC, Sermer M, Crean AM, Wald RM
Cardiol Young 2017 Oct;27(8):1529-1537. Epub 2017 Apr 17 doi: 10.1017/S1047951117000658. PMID: 28412993
Coronary artery anomalies in children: what is the risk?
Brothers JA
Curr Opin Pediatr 2016 Oct;28(5):590-6. doi: 10.1097/MOP.0000000000000399. PMID: 27379803

Therapy

Outcomes in anomalous aortic origin of a coronary artery after surgical reimplantation.
Bonilla-Ramirez C, Molossi S, Sachdeva S, Reaves-O'Neal D, Masand P, Mery CM, Caldarone CA, McKenzie ED, Binsalamah ZM
J Thorac Cardiovasc Surg 2021 Oct;162(4):1191-1199. Epub 2021 Jan 5 doi: 10.1016/j.jtcvs.2020.12.100. PMID: 33541731
Acquired and congenital coronary artery abnormalities.
Young ML, McLeary M, Chan KC
Cardiol Young 2017 Jan;27(S1):S31-S35. doi: 10.1017/S1047951116002201. PMID: 28084958
Repair of anomalous origin of the left coronary artery from the pulmonary artery in infants.
Kazmierczak PA, Ostrowska K, Dryzek P, Moll JA, Moll JJ
Interact Cardiovasc Thorac Surg 2013 Jun;16(6):797-801. Epub 2013 Feb 26 doi: 10.1093/icvts/ivt061. PMID: 23442939Free PMC Article
Anomalous aortic origin of coronary arteries from the opposite sinus: a critical appraisal of risk.
Peñalver JM, Mosca RS, Weitz D, Phoon CK
BMC Cardiovasc Disord 2012 Oct 1;12:83. doi: 10.1186/1471-2261-12-83. PMID: 23025810Free PMC Article
Anomalous left coronary artery from the pulmonary artery: intermediate results of coronary elongation.
Novick WM, Li XF, Anic D, Baskevitch A, Sandoval N, Gilbert CL, Di Sessa TG
Interact Cardiovasc Thorac Surg 2009 Nov;9(5):814-8. Epub 2009 Aug 13 doi: 10.1510/icvts.2009.208215. PMID: 19679610

Prognosis

Anomalous origins of the coronary arteries: current knowledge and future perspectives.
Mazine A, Fernandes IM, Haller C, Hickey EJ
Curr Opin Cardiol 2019 Sep;34(5):543-551. doi: 10.1097/HCO.0000000000000663. PMID: 31335330
Introduction to anomalous aortic origin of a coronary artery.
Brothers JA
Congenit Heart Dis 2017 Sep;12(5):600-602. Epub 2017 Jun 27 doi: 10.1111/chd.12497. PMID: 28653465
Acquired and congenital coronary artery abnormalities.
Young ML, McLeary M, Chan KC
Cardiol Young 2017 Jan;27(S1):S31-S35. doi: 10.1017/S1047951116002201. PMID: 28084958
Coronary artery anomalies in children: what is the risk?
Brothers JA
Curr Opin Pediatr 2016 Oct;28(5):590-6. doi: 10.1097/MOP.0000000000000399. PMID: 27379803
Anomalous Aortic Origin of a Coronary Artery is Always a Surgical Disease.
Vouhé PR
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2016;19(1):25-9. doi: 10.1053/j.pcsu.2015.12.007. PMID: 27060039

Clinical prediction guides

Mitral intervention for anomalous left coronary artery from the pulmonary artery: midterm outcomes.
Zhang W, Hu R, Jiang Q, Zhu H, Qiu L, Dong W, Zhang H
Eur J Cardiothorac Surg 2023 Feb 3;63(2) doi: 10.1093/ejcts/ezac521. PMID: 36321959
Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery: A Retrospective Multicenter Study.
Cashen K, Kwiatkowski DM, Riley CM, Buckley J, Sassalos P, Gowda KN, Iliopoulos I, Bakar A, Chiwane S, Badheka A, Moser EAS, Mastropietro CW; Collaborative Research from the Pediatric Cardiac Intensive Care Society (CoRe-PCICS) Investigators
Pediatr Crit Care Med 2021 Dec 1;22(12):e626-e635. doi: 10.1097/PCC.0000000000002820. PMID: 34432672
Paediatric-onset coronary artery anomalies in pregnancy: a single-centre experience and systematic literature review.
Keir M, Bhagra C, Vatenmakher D, Arancibia-Galilea F, Jansen K, Toh N, Silversides CK, Colman J, Siu SC, Sermer M, Crean AM, Wald RM
Cardiol Young 2017 Oct;27(8):1529-1537. Epub 2017 Apr 17 doi: 10.1017/S1047951117000658. PMID: 28412993
Anomalous Aortic Origin of a Coronary Artery From the Inappropriate Sinus of Valsalva.
Cheezum MK, Liberthson RR, Shah NR, Villines TC, O'Gara PT, Landzberg MJ, Blankstein R
J Am Coll Cardiol 2017 Mar 28;69(12):1592-1608. doi: 10.1016/j.jacc.2017.01.031. PMID: 28335843
Acquired and congenital coronary artery abnormalities.
Young ML, McLeary M, Chan KC
Cardiol Young 2017 Jan;27(S1):S31-S35. doi: 10.1017/S1047951116002201. PMID: 28084958

Recent systematic reviews

Coronary Artery Bypass Surgery to Treat Anomalous Origin of Coronary Arteries in Adults: A Systematic Review.
Alzghari T, Sandner S, Di Franco A, Harik L, Perezgorvas-Olaria R, Soletti G Jr, Dimagli A, Cancelli G, Demetres M, Lau C, Girardi LN, Gaudino M
Heart Lung Circ 2023 Dec;32(12):1500-1511. Epub 2023 Nov 3 doi: 10.1016/j.hlc.2023.09.014. PMID: 37923692
Paediatric-onset coronary artery anomalies in pregnancy: a single-centre experience and systematic literature review.
Keir M, Bhagra C, Vatenmakher D, Arancibia-Galilea F, Jansen K, Toh N, Silversides CK, Colman J, Siu SC, Sermer M, Crean AM, Wald RM
Cardiol Young 2017 Oct;27(8):1529-1537. Epub 2017 Apr 17 doi: 10.1017/S1047951117000658. PMID: 28412993

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...