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Increased circulating trypsinogen

MedGen UID:
1677064
Concept ID:
C4324557
Finding
Synonym: Increased immunoreactive trypsinogen
 
HPO: HP:0032493

Definition

An abnormally high concentration of trypsinogen in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased circulating trypsinogen

Recent clinical studies

Etiology

Stewart JA, Koistinen R, Lempiäinen A, Hotakainen K, Salminen US, Vakkuri A, Wennervirta J, Stenman UH, Koistinen H
Scand J Clin Lab Invest 2020 Dec;80(8):640-643. Epub 2020 Sep 23 doi: 10.1080/00365513.2020.1824297. PMID: 32967482
Jeong YK, Kim H
Int J Mol Sci 2017 Oct 25;18(11) doi: 10.3390/ijms18112239. PMID: 29068376Free PMC Article
Kimmel PL, Tenner S, Habwe VQ, Henry J, Lakshminarayan S, Steinberg W
Pancreas 1995 May;10(4):325-30. doi: 10.1097/00006676-199505000-00001. PMID: 7540759
Colombo C, Maiavacca R, Ronchi M, Bottani P, Stripparo L, Corbetta C, Sereni LP
J Pediatr Gastroenterol Nutr 1989 Aug;9(2):194-9. doi: 10.1097/00005176-198908000-00011. PMID: 2478689
Dubick MA, Conteas CN, Billy HT, Majumdar AP, Geokas MC
Gut 1987 Mar;28(3):330-5. doi: 10.1136/gut.28.3.330. PMID: 2436981Free PMC Article

Diagnosis

Bush N, Akshintala VS
Curr Opin Gastroenterol 2023 Sep 1;39(5):403-410. Epub 2023 Jun 22 doi: 10.1097/MOG.0000000000000961. PMID: 37389417
Stewart JA, Koistinen R, Lempiäinen A, Hotakainen K, Salminen US, Vakkuri A, Wennervirta J, Stenman UH, Koistinen H
Scand J Clin Lab Invest 2020 Dec;80(8):640-643. Epub 2020 Sep 23 doi: 10.1080/00365513.2020.1824297. PMID: 32967482
Soave D, Miller MR, Keenan K, Li W, Gong J, Ip W, Accurso F, Sun L, Rommens JM, Sontag M, Durie PR, Strug LJ
Diabetes 2014 Jun;63(6):2114-9. Epub 2014 Feb 18 doi: 10.2337/db13-1464. PMID: 24550193Free PMC Article
Lippi G, Valentino M, Cervellin G
Crit Rev Clin Lab Sci 2012 Jan-Feb;49(1):18-31. doi: 10.3109/10408363.2012.658354. PMID: 22339380
Durie PR, Forstner GG, Gaskin KJ, Weizman Z, Kopelman HR, Ellis L, Largman C
J Pediatr 1985 Feb;106(2):233-8. doi: 10.1016/s0022-3476(85)80293-6. PMID: 3968610

Therapy

Stewart JA, Koistinen R, Lempiäinen A, Hotakainen K, Salminen US, Vakkuri A, Wennervirta J, Stenman UH, Koistinen H
Scand J Clin Lab Invest 2020 Dec;80(8):640-643. Epub 2020 Sep 23 doi: 10.1080/00365513.2020.1824297. PMID: 32967482
Jeong YK, Kim H
Int J Mol Sci 2017 Oct 25;18(11) doi: 10.3390/ijms18112239. PMID: 29068376Free PMC Article
Soave D, Miller MR, Keenan K, Li W, Gong J, Ip W, Accurso F, Sun L, Rommens JM, Sontag M, Durie PR, Strug LJ
Diabetes 2014 Jun;63(6):2114-9. Epub 2014 Feb 18 doi: 10.2337/db13-1464. PMID: 24550193Free PMC Article
Annibale B, Ribaldi S, Anania MC, Stagnitti F, Strom R, Corleto V, Delle Fave G
Pancreas 1989;4(6):674-9. doi: 10.1097/00006676-198912000-00004. PMID: 2573057

Prognosis

Soave D, Miller MR, Keenan K, Li W, Gong J, Ip W, Accurso F, Sun L, Rommens JM, Sontag M, Durie PR, Strug LJ
Diabetes 2014 Jun;63(6):2114-9. Epub 2014 Feb 18 doi: 10.2337/db13-1464. PMID: 24550193Free PMC Article
Segal I, Chaloner C, Douglas J, John KD, Zaidi A, Cotter L, Appelros S, Borgström A, Braganza JM
Am J Gastroenterol 2002 Apr;97(4):883-92. doi: 10.1111/j.1572-0241.2002.05604.x. PMID: 12003423
Durie PR, Forstner GG, Gaskin KJ, Weizman Z, Kopelman HR, Ellis L, Largman C
J Pediatr 1985 Feb;106(2):233-8. doi: 10.1016/s0022-3476(85)80293-6. PMID: 3968610
Durie PR, Gaskin KJ, Ogilvie JE, Smith CR, Forstner GG, Largman C
J Pediatr Gastroenterol Nutr 1985 Apr;4(2):199-207. doi: 10.1097/00005176-198504000-00008. PMID: 2580962

Clinical prediction guides

Stewart JA, Koistinen R, Lempiäinen A, Hotakainen K, Salminen US, Vakkuri A, Wennervirta J, Stenman UH, Koistinen H
Scand J Clin Lab Invest 2020 Dec;80(8):640-643. Epub 2020 Sep 23 doi: 10.1080/00365513.2020.1824297. PMID: 32967482
Soave D, Miller MR, Keenan K, Li W, Gong J, Ip W, Accurso F, Sun L, Rommens JM, Sontag M, Durie PR, Strug LJ
Diabetes 2014 Jun;63(6):2114-9. Epub 2014 Feb 18 doi: 10.2337/db13-1464. PMID: 24550193Free PMC Article
Annibale B, Ribaldi S, Anania MC, Stagnitti F, Strom R, Corleto V, Delle Fave G
Pancreas 1989;4(6):674-9. doi: 10.1097/00006676-198912000-00004. PMID: 2573057
Dubick MA, Conteas CN, Billy HT, Majumdar AP, Geokas MC
Gut 1987 Mar;28(3):330-5. doi: 10.1136/gut.28.3.330. PMID: 2436981Free PMC Article

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