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Corrected Prolonged QT Interval by ECG Finding

MedGen UID:
167789
Concept ID:
C0855333
Finding
Synonyms: Corrected Prolonged QT Interval; Corrected Prolonged QT Interval by EKG Finding

Definition

An electrocardiographic finding in which the QTc interval corrected for heart rate is prolonged. Thresholds for different age, gender, and patient populations exist. (CDISC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCorrected Prolonged QT Interval by ECG Finding

Professional guidelines

PubMed

Wilde AAM, Amin AS, Postema PG
Heart 2022 Mar;108(5):332-338. Epub 2021 May 26 doi: 10.1136/heartjnl-2020-318259. PMID: 34039680Free PMC Article
Indraratna P, Tardo D, Delves M, Szirt R, Ng B
J Gen Intern Med 2020 Mar;35(3):865-873. Epub 2019 Oct 25 doi: 10.1007/s11606-019-05477-7. PMID: 31654357Free PMC Article
Thomas SH, Behr ER
Br J Clin Pharmacol 2016 Mar;81(3):420-7. Epub 2015 Oct 26 doi: 10.1111/bcp.12726. PMID: 26183037Free PMC Article

Recent clinical studies

Etiology

Wilde AAM, Amin AS, Postema PG
Heart 2022 Mar;108(5):332-338. Epub 2021 May 26 doi: 10.1136/heartjnl-2020-318259. PMID: 34039680Free PMC Article
Khatib R, Sabir FRN, Omari C, Pepper C, Tayebjee MH
Postgrad Med J 2021 Jul;97(1149):452-458. Epub 2020 Oct 29 doi: 10.1136/postgradmedj-2020-138661. PMID: 33122341Free PMC Article
Thomas SH, Behr ER
Br J Clin Pharmacol 2016 Mar;81(3):420-7. Epub 2015 Oct 26 doi: 10.1111/bcp.12726. PMID: 26183037Free PMC Article
Postema PG, Wilde AA
Curr Cardiol Rev 2014 Aug;10(3):287-94. doi: 10.2174/1573403x10666140514103612. PMID: 24827793Free PMC Article
Trinkley KE, Page RL 2nd, Lien H, Yamanouye K, Tisdale JE
Curr Med Res Opin 2013 Dec;29(12):1719-26. Epub 2013 Sep 23 doi: 10.1185/03007995.2013.840568. PMID: 24020938

Diagnosis

Christou GA, Vlahos AP, Christou KA, Mantzoukas S, Drougias CA, Christodoulou DK
Cardiology 2022;147(5-6):578-586. Epub 2022 Aug 10 doi: 10.1159/000526385. PMID: 35947943
Wilde AAM, Amin AS, Postema PG
Heart 2022 Mar;108(5):332-338. Epub 2021 May 26 doi: 10.1136/heartjnl-2020-318259. PMID: 34039680Free PMC Article
Matsui K, Mukai Y, Sakakura K, Wada K, Nakamura T, Kawabata A, Terakawa N, Hayakawa N, Kusano K, Hosomi K, Yokoyama S, Takada M
Int J Clin Pharmacol Ther 2021 Jan;59(1):63-70. doi: 10.5414/CP203843. PMID: 33026317
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118
Tisdale JE, Jaynes HA, Kingery JR, Mourad NA, Trujillo TN, Overholser BR, Kovacs RJ
Circ Cardiovasc Qual Outcomes 2013 Jul;6(4):479-87. Epub 2013 May 28 doi: 10.1161/CIRCOUTCOMES.113.000152. PMID: 23716032Free PMC Article

Therapy

Matsui K, Mukai Y, Sakakura K, Wada K, Nakamura T, Kawabata A, Terakawa N, Hayakawa N, Kusano K, Hosomi K, Yokoyama S, Takada M
Int J Clin Pharmacol Ther 2021 Jan;59(1):63-70. doi: 10.5414/CP203843. PMID: 33026317
Vicente J
J Electrocardiol 2018 Nov-Dec;51(6S):S98-S102. Epub 2018 Aug 7 doi: 10.1016/j.jelectrocard.2018.08.003. PMID: 30121123
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118
Thomas SH, Behr ER
Br J Clin Pharmacol 2016 Mar;81(3):420-7. Epub 2015 Oct 26 doi: 10.1111/bcp.12726. PMID: 26183037Free PMC Article
Beach SR, Celano CM, Noseworthy PA, Januzzi JL, Huffman JC
Psychosomatics 2013 Jan-Feb;54(1):1-13. doi: 10.1016/j.psym.2012.11.001. PMID: 23295003

Prognosis

Lee W, Vandenberk B, Raj SR, Lee SS
Gut Liver 2022 Nov 15;16(6):849-860. Epub 2022 Jul 22 doi: 10.5009/gnl210537. PMID: 35864808Free PMC Article
Odening KE, van der Linde HJ, Ackerman MJ, Volders PGA, Ter Bekke RMA
Eur Heart J 2022 Aug 21;43(32):3018-3028. doi: 10.1093/eurheartj/ehac135. PMID: 35445703Free PMC Article
Cohen RB, Dai M, Aizer A, Barbhaiya C, Peterson C, Bernstein S, Park DS, Spinelli M, Chinitz LA, Jankelson L
Resuscitation 2021 May;162:171-179. Epub 2021 Feb 27 doi: 10.1016/j.resuscitation.2021.02.029. PMID: 33652119
Zhang N, Gong M, Tse G, Zhang Z, Meng L, Yan BP, Zhang L, Wu G, Xia Y, Xin-Yan G, Li G, Liu T
Pacing Clin Electrophysiol 2018 Mar;41(3):321-327. Epub 2018 Feb 16 doi: 10.1111/pace.13292. PMID: 29380395
Tisdale JE, Jaynes HA, Kingery JR, Mourad NA, Trujillo TN, Overholser BR, Kovacs RJ
Circ Cardiovasc Qual Outcomes 2013 Jul;6(4):479-87. Epub 2013 May 28 doi: 10.1161/CIRCOUTCOMES.113.000152. PMID: 23716032Free PMC Article

Clinical prediction guides

Cohen RB, Dai M, Aizer A, Barbhaiya C, Peterson C, Bernstein S, Park DS, Spinelli M, Chinitz LA, Jankelson L
Resuscitation 2021 May;162:171-179. Epub 2021 Feb 27 doi: 10.1016/j.resuscitation.2021.02.029. PMID: 33652119
Matsui K, Mukai Y, Sakakura K, Wada K, Nakamura T, Kawabata A, Terakawa N, Hayakawa N, Kusano K, Hosomi K, Yokoyama S, Takada M
Int J Clin Pharmacol Ther 2021 Jan;59(1):63-70. doi: 10.5414/CP203843. PMID: 33026317
Zhang N, Gong M, Tse G, Zhang Z, Meng L, Yan BP, Zhang L, Wu G, Xia Y, Xin-Yan G, Li G, Liu T
Pacing Clin Electrophysiol 2018 Mar;41(3):321-327. Epub 2018 Feb 16 doi: 10.1111/pace.13292. PMID: 29380395
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118
Tisdale JE, Jaynes HA, Kingery JR, Mourad NA, Trujillo TN, Overholser BR, Kovacs RJ
Circ Cardiovasc Qual Outcomes 2013 Jul;6(4):479-87. Epub 2013 May 28 doi: 10.1161/CIRCOUTCOMES.113.000152. PMID: 23716032Free PMC Article

Recent systematic reviews

Mahendran S, Gupta I, Davis J, Davis AJ, Orchard JW, Orchard JJ
Clin Cardiol 2023 Sep;46(9):1106-1115. Epub 2023 Jul 20 doi: 10.1002/clc.24093. PMID: 37470093Free PMC Article
Beach SR, Gross AF, Hartney KE, Taylor JB, Rundell JR
Gen Hosp Psychiatry 2020 Nov-Dec;67:42-50. Epub 2020 Aug 22 doi: 10.1016/j.genhosppsych.2020.08.008. PMID: 32979582
Zhang N, Gong M, Tse G, Zhang Z, Meng L, Yan BP, Zhang L, Wu G, Xia Y, Xin-Yan G, Li G, Liu T
Pacing Clin Electrophysiol 2018 Mar;41(3):321-327. Epub 2018 Feb 16 doi: 10.1111/pace.13292. PMID: 29380395
Porta-Sánchez A, Gilbert C, Spears D, Amir E, Chan J, Nanthakumar K, Thavendiranathan P
J Am Heart Assoc 2017 Dec 7;6(12) doi: 10.1161/JAHA.117.007724. PMID: 29217664Free PMC Article
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118

Supplemental Content

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