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Infection causing encephalomyelitis

MedGen UID:
167798
•Concept ID:
C0856705
•
Disease or Syndrome
Synonyms: Infectious Encephalomyelitis; Infectious encephalomyelitis
SNOMED CT: Infection causing encephalomyelitis (721249007); Infectious encephalomyelitis (721249007)

Definition

An infectious process that affects the brain and spinal cord tissues. It is usually caused by viruses. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfection causing encephalomyelitis

Professional guidelines

PubMed

Post-COVID-19 syndrome: epidemiology, diagnostic criteria and pathogenic mechanisms involved.
Carod-Artal FJ
Rev Neurol 2021 Jun 1;72(11):384-396. doi: 10.33588/rn.7211.2021230. PMID: 34042167
Guidelines for diagnosis and treatment in neurology - Lyme neuroborreliosis.
Rauer S, Kastenbauer S, Hofmann H, Fingerle V, Huppertz HI, Hunfeld KP, Krause A, Ruf B, Dersch R; Consensus group
Ger Med Sci 2020;18:Doc03. Epub 2020 Feb 27 doi: 10.3205/000279. PMID: 32341686Free PMC Article
Virus and Immune-Mediated Encephalitides: Epidemiology, Diagnosis, Treatment, and Prevention.
Bale JF Jr
Pediatr Neurol 2015 Jul;53(1):3-12. Epub 2015 Mar 19 doi: 10.1016/j.pediatrneurol.2015.03.013. PMID: 25957806

Recent clinical studies

Etiology

Unexplained post-acute infection syndromes.
Choutka J, Jansari V, Hornig M, Iwasaki A
Nat Med 2022 May;28(5):911-923. Epub 2022 May 18 doi: 10.1038/s41591-022-01810-6. PMID: 35585196
Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis?
Bornstein SR, Voit-Bak K, Donate T, Rodionov RN, Gainetdinov RR, Tselmin S, Kanczkowski W, Müller GM, Achleitner M, Wang J, Licinio J, Bauer M, Young AH, Thuret S, Bechmann N, Straube R
Mol Psychiatry 2022 Jan;27(1):34-37. Epub 2021 Jun 17 doi: 10.1038/s41380-021-01148-4. PMID: 34140635Free PMC Article
Post-COVID-19 syndrome: epidemiology, diagnostic criteria and pathogenic mechanisms involved.
Carod-Artal FJ
Rev Neurol 2021 Jun 1;72(11):384-396. doi: 10.33588/rn.7211.2021230. PMID: 34042167
Long COVID or post-COVID-19 syndrome: putative pathophysiology, risk factors, and treatments.
Yong SJ
Infect Dis (Lond) 2021 Oct;53(10):737-754. Epub 2021 May 22 doi: 10.1080/23744235.2021.1924397. PMID: 34024217Free PMC Article
Adenovirus-Associated Central Nervous System Disease in Children.
Schwartz KL, Richardson SE, MacGregor D, Mahant S, Raghuram K, Bitnun A
J Pediatr 2019 Feb;205:130-137. Epub 2018 Nov 6 doi: 10.1016/j.jpeds.2018.09.036. PMID: 30413311

Diagnosis

Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis/chronic fatigue syndrome.
Sukocheva OA, Maksoud R, Beeraka NM, Madhunapantula SV, Sinelnikov M, Nikolenko VN, Neganova ME, Klochkov SG, Amjad Kamal M, Staines DR, Marshall-Gradisnik S
J Adv Res 2022 Sep;40:179-196. Epub 2021 Nov 26 doi: 10.1016/j.jare.2021.11.013. PMID: 36100326Free PMC Article
Unexplained post-acute infection syndromes.
Choutka J, Jansari V, Hornig M, Iwasaki A
Nat Med 2022 May;28(5):911-923. Epub 2022 May 18 doi: 10.1038/s41591-022-01810-6. PMID: 35585196
Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis?
Bornstein SR, Voit-Bak K, Donate T, Rodionov RN, Gainetdinov RR, Tselmin S, Kanczkowski W, Müller GM, Achleitner M, Wang J, Licinio J, Bauer M, Young AH, Thuret S, Bechmann N, Straube R
Mol Psychiatry 2022 Jan;27(1):34-37. Epub 2021 Jun 17 doi: 10.1038/s41380-021-01148-4. PMID: 34140635Free PMC Article
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Where will the drugs come from?
Toogood PL, Clauw DJ, Phadke S, Hoffman D
Pharmacol Res 2021 Mar;165:105465. Epub 2021 Jan 30 doi: 10.1016/j.phrs.2021.105465. PMID: 33529750
MOG antibody-associated encephalomyelitis/encephalitis.
Salama S, Khan M, Pardo S, Izbudak I, Levy M
Mult Scler 2019 Oct;25(11):1427-1433. Epub 2019 Mar 25 doi: 10.1177/1352458519837705. PMID: 30907249Free PMC Article

Therapy

Measles.
Hübschen JM, Gouandjika-Vasilache I, Dina J
Lancet 2022 Feb 12;399(10325):678-690. Epub 2022 Jan 28 doi: 10.1016/S0140-6736(21)02004-3. PMID: 35093206
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Where will the drugs come from?
Toogood PL, Clauw DJ, Phadke S, Hoffman D
Pharmacol Res 2021 Mar;165:105465. Epub 2021 Jan 30 doi: 10.1016/j.phrs.2021.105465. PMID: 33529750
Human and novel coronavirus infections in children: a review.
Rajapakse N, Dixit D
Paediatr Int Child Health 2021 Feb;41(1):36-55. Epub 2020 Jun 25 doi: 10.1080/20469047.2020.1781356. PMID: 32584199
MOG antibody-associated encephalomyelitis/encephalitis.
Salama S, Khan M, Pardo S, Izbudak I, Levy M
Mult Scler 2019 Oct;25(11):1427-1433. Epub 2019 Mar 25 doi: 10.1177/1352458519837705. PMID: 30907249Free PMC Article
Neurologic and neuropsychiatric syndrome features of mold and mycotoxin exposure.
Empting LD
Toxicol Ind Health 2009 Oct-Nov;25(9-10):577-81. doi: 10.1177/0748233709348393. PMID: 19854819

Prognosis

Bioinformatics and systems biology approach to identify the pathogenetic link of Long COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Lv Y, Zhang T, Cai J, Huang C, Zhan S, Liu J
Front Immunol 2022;13:952987. Epub 2022 Sep 16 doi: 10.3389/fimmu.2022.952987. PMID: 36189286Free PMC Article
Neurological consequences of COVID-19.
Brola W, Wilski M
Pharmacol Rep 2022 Dec;74(6):1208-1222. Epub 2022 Sep 30 doi: 10.1007/s43440-022-00424-6. PMID: 36180640Free PMC Article
Neurological Complications of Dengue Fever.
Trivedi S, Chakravarty A
Curr Neurol Neurosci Rep 2022 Aug;22(8):515-529. Epub 2022 Jun 21 doi: 10.1007/s11910-022-01213-7. PMID: 35727463Free PMC Article
Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events: population based cohort and self-controlled case series analysis.
Li X, Raventós B, Roel E, Pistillo A, Martinez-Hernandez E, Delmestri A, Reyes C, Strauss V, Prieto-Alhambra D, Burn E, Duarte-Salles T
BMJ 2022 Mar 16;376:e068373. doi: 10.1136/bmj-2021-068373. PMID: 35296468Free PMC Article
Adenovirus-Associated Central Nervous System Disease in Children.
Schwartz KL, Richardson SE, MacGregor D, Mahant S, Raghuram K, Bitnun A
J Pediatr 2019 Feb;205:130-137. Epub 2018 Nov 6 doi: 10.1016/j.jpeds.2018.09.036. PMID: 30413311

Clinical prediction guides

Analysis of post COVID-19 condition and its overlap with myalgic encephalomyelitis/chronic fatigue syndrome.
Sukocheva OA, Maksoud R, Beeraka NM, Madhunapantula SV, Sinelnikov M, Nikolenko VN, Neganova ME, Klochkov SG, Amjad Kamal M, Staines DR, Marshall-Gradisnik S
J Adv Res 2022 Sep;40:179-196. Epub 2021 Nov 26 doi: 10.1016/j.jare.2021.11.013. PMID: 36100326Free PMC Article
Neurological Complications of Dengue Fever.
Trivedi S, Chakravarty A
Curr Neurol Neurosci Rep 2022 Aug;22(8):515-529. Epub 2022 Jun 21 doi: 10.1007/s11910-022-01213-7. PMID: 35727463Free PMC Article
Post COVID syndrome: a new challenge for medicine.
Tirelli U, Taibi R, Chirumbolo S
Eur Rev Med Pharmacol Sci 2021 Jun;25(12):4422-4425. doi: 10.26355/eurrev_202106_26154. PMID: 34227079
Human and novel coronavirus infections in children: a review.
Rajapakse N, Dixit D
Paediatr Int Child Health 2021 Feb;41(1):36-55. Epub 2020 Jun 25 doi: 10.1080/20469047.2020.1781356. PMID: 32584199
Adenovirus-Associated Central Nervous System Disease in Children.
Schwartz KL, Richardson SE, MacGregor D, Mahant S, Raghuram K, Bitnun A
J Pediatr 2019 Feb;205:130-137. Epub 2018 Nov 6 doi: 10.1016/j.jpeds.2018.09.036. PMID: 30413311

Recent systematic reviews

Genetics of COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review.
Tziastoudi M, Cholevas C, Stefanidis I, Theoharides TC
Ann Clin Transl Neurol 2022 Nov;9(11):1838-1857. Epub 2022 Oct 6 doi: 10.1002/acn3.51631. PMID: 36204816Free PMC Article
Autoimmune encephalitis associated with COVID-19: A systematic review.
Nabizadeh F, Balabandian M, Sodeifian F, Rezaei N, Rostami MR, Naser Moghadasi A
Mult Scler Relat Disord 2022 Jun;62:103795. Epub 2022 Apr 6 doi: 10.1016/j.msard.2022.103795. PMID: 35472834Free PMC Article
Central neuroinflammation in Covid-19: a systematic review of 182 cases with encephalitis, acute disseminated encephalomyelitis, and necrotizing encephalopathies.
Zamani R, Pouremamali R, Rezaei N
Rev Neurosci 2022 Jun 27;33(4):397-412. Epub 2021 Sep 17 doi: 10.1515/revneuro-2021-0082. PMID: 34536341
Association of CNS demyelination and COVID-19 infection: an updated systematic review.
Ismail II, Salama S
J Neurol 2022 Feb;269(2):541-576. Epub 2021 Aug 12 doi: 10.1007/s00415-021-10752-x. PMID: 34386902Free PMC Article
Acute Transverse Myelitis (ATM):Clinical Review of 43 Patients With COVID-19-Associated ATM and 3 Post-Vaccination ATM Serious Adverse Events With the ChAdOx1 nCoV-19 Vaccine (AZD1222).
Román GC, Gracia F, Torres A, Palacios A, Gracia K, Harris D
Front Immunol 2021;12:653786. Epub 2021 Apr 26 doi: 10.3389/fimmu.2021.653786. PMID: 33981305Free PMC Article

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