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Carcinoma of colon, stage IV

MedGen UID:
167826
•Concept ID:
C0861461
•
Neoplastic Process
Synonym: Colon cancer stage 4
SNOMED CT: Carcinoma of colon, stage IV (422985007); Colon cancer stage 4 (422985007)

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCarcinoma of colon, stage IV

Professional guidelines

PubMed

Advances in Exosome Research in the Management of Lung Cancer.
Shen H, Cao D, Zhang X
Curr Top Med Chem 2023;23(10):921-930. doi: 10.2174/1568026623666230504101208. PMID: 37150988
Management of the adenocarcinoma of the upper rectum: a reappraisal.
Pechlivanides G, Gourtsoyianni S, Gouvas N, Sougklakos J, Xynos E
Updates Surg 2021 Apr;73(2):513-526. Epub 2020 Oct 27 doi: 10.1007/s13304-020-00903-6. PMID: 33108641
Management of colorectal T1 carcinoma treated by endoscopic resection.
Saitoh Y, Inaba Y, Sasaki T, Sugiyama R, Sukegawa R, Fujiya M
Dig Endosc 2016 Apr;28(3):324-9. Epub 2015 Sep 6 doi: 10.1111/den.12503. PMID: 26076802

Recent clinical studies

Etiology

Amino acids and risk of colon adenocarcinoma: a Mendelian randomization study.
Wang Y, Jia Z, Wang Q, Zhu Z
BMC Cancer 2023 Oct 28;23(1):1041. doi: 10.1186/s12885-023-11514-w. PMID: 37898769Free PMC Article
Management of the adenocarcinoma of the upper rectum: a reappraisal.
Pechlivanides G, Gourtsoyianni S, Gouvas N, Sougklakos J, Xynos E
Updates Surg 2021 Apr;73(2):513-526. Epub 2020 Oct 27 doi: 10.1007/s13304-020-00903-6. PMID: 33108641
Role of ion channels in gastrointestinal cancer.
Anderson KJ, Cormier RT, Scott PM
World J Gastroenterol 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. PMID: 31636470Free PMC Article
Colorectal cancer.
Brenner H, Kloor M, Pox CP
Lancet 2014 Apr 26;383(9927):1490-1502. Epub 2013 Nov 11 doi: 10.1016/S0140-6736(13)61649-9. PMID: 24225001
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial.
Mitsudomi T, Morita S, Yatabe Y, Negoro S, Okamoto I, Tsurutani J, Seto T, Satouchi M, Tada H, Hirashima T, Asami K, Katakami N, Takada M, Yoshioka H, Shibata K, Kudoh S, Shimizu E, Saito H, Toyooka S, Nakagawa K, Fukuoka M; West Japan Oncology Group
Lancet Oncol 2010 Feb;11(2):121-8. Epub 2009 Dec 18 doi: 10.1016/S1470-2045(09)70364-X. PMID: 20022809

Diagnosis

Amino acids and risk of colon adenocarcinoma: a Mendelian randomization study.
Wang Y, Jia Z, Wang Q, Zhu Z
BMC Cancer 2023 Oct 28;23(1):1041. doi: 10.1186/s12885-023-11514-w. PMID: 37898769Free PMC Article
Prognostic value of primary tumor location in colorectal cancer: an updated meta-analysis.
Gholamalizadeh H, Zafari N, Velayati M, Fiuji H, Maftooh M, Ghorbani E, Hassanian SM, Khazaei M, Ferns GA, Nazari E, Avan A
Clin Exp Med 2023 Dec;23(8):4369-4383. Epub 2023 Jul 5 doi: 10.1007/s10238-023-01120-2. PMID: 37405571
Advances in Exosome Research in the Management of Lung Cancer.
Shen H, Cao D, Zhang X
Curr Top Med Chem 2023;23(10):921-930. doi: 10.2174/1568026623666230504101208. PMID: 37150988
Colorectal cancer.
Brenner H, Kloor M, Pox CP
Lancet 2014 Apr 26;383(9927):1490-1502. Epub 2013 Nov 11 doi: 10.1016/S0140-6736(13)61649-9. PMID: 24225001
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial.
Mitsudomi T, Morita S, Yatabe Y, Negoro S, Okamoto I, Tsurutani J, Seto T, Satouchi M, Tada H, Hirashima T, Asami K, Katakami N, Takada M, Yoshioka H, Shibata K, Kudoh S, Shimizu E, Saito H, Toyooka S, Nakagawa K, Fukuoka M; West Japan Oncology Group
Lancet Oncol 2010 Feb;11(2):121-8. Epub 2009 Dec 18 doi: 10.1016/S1470-2045(09)70364-X. PMID: 20022809

Therapy

Amino acids and risk of colon adenocarcinoma: a Mendelian randomization study.
Wang Y, Jia Z, Wang Q, Zhu Z
BMC Cancer 2023 Oct 28;23(1):1041. doi: 10.1186/s12885-023-11514-w. PMID: 37898769Free PMC Article
Association Between Survival and Metastatic Site in Mismatch Repair-Deficient Metastatic Colorectal Cancer Treated With First-line Pembrolizumab.
Saberzadeh-Ardestani B, Jones JC, Hubbard JM, McWilliams RR, Halfdanarson TR, Shi Q, Sonbol MB, Ticku J, Jin Z, Sinicrope FA
JAMA Netw Open 2023 Feb 1;6(2):e230400. doi: 10.1001/jamanetworkopen.2023.0400. PMID: 36811859Free PMC Article
Role of ion channels in gastrointestinal cancer.
Anderson KJ, Cormier RT, Scott PM
World J Gastroenterol 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. PMID: 31636470Free PMC Article
The efficacy of chemotherapy and operation in patients with colorectal neuroendocrine carcinoma.
Wu Z, Yu D, Zhao S, Gao P, Song Y, Sun Y, Chen X, Wang Z
J Surg Res 2018 May;225:54-67. Epub 2018 Jan 19 doi: 10.1016/j.jss.2017.12.035. PMID: 29605035
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial.
Mitsudomi T, Morita S, Yatabe Y, Negoro S, Okamoto I, Tsurutani J, Seto T, Satouchi M, Tada H, Hirashima T, Asami K, Katakami N, Takada M, Yoshioka H, Shibata K, Kudoh S, Shimizu E, Saito H, Toyooka S, Nakagawa K, Fukuoka M; West Japan Oncology Group
Lancet Oncol 2010 Feb;11(2):121-8. Epub 2009 Dec 18 doi: 10.1016/S1470-2045(09)70364-X. PMID: 20022809

Prognosis

Amino acids and risk of colon adenocarcinoma: a Mendelian randomization study.
Wang Y, Jia Z, Wang Q, Zhu Z
BMC Cancer 2023 Oct 28;23(1):1041. doi: 10.1186/s12885-023-11514-w. PMID: 37898769Free PMC Article
Prognostic value of primary tumor location in colorectal cancer: an updated meta-analysis.
Gholamalizadeh H, Zafari N, Velayati M, Fiuji H, Maftooh M, Ghorbani E, Hassanian SM, Khazaei M, Ferns GA, Nazari E, Avan A
Clin Exp Med 2023 Dec;23(8):4369-4383. Epub 2023 Jul 5 doi: 10.1007/s10238-023-01120-2. PMID: 37405571
Management of the adenocarcinoma of the upper rectum: a reappraisal.
Pechlivanides G, Gourtsoyianni S, Gouvas N, Sougklakos J, Xynos E
Updates Surg 2021 Apr;73(2):513-526. Epub 2020 Oct 27 doi: 10.1007/s13304-020-00903-6. PMID: 33108641
Role of ion channels in gastrointestinal cancer.
Anderson KJ, Cormier RT, Scott PM
World J Gastroenterol 2019 Oct 14;25(38):5732-5772. doi: 10.3748/wjg.v25.i38.5732. PMID: 31636470Free PMC Article
Colorectal cancer.
Brenner H, Kloor M, Pox CP
Lancet 2014 Apr 26;383(9927):1490-1502. Epub 2013 Nov 11 doi: 10.1016/S0140-6736(13)61649-9. PMID: 24225001

Clinical prediction guides

Temporal trends in age- and stage-specific incidence of colorectal adenocarcinomas in Germany.
Waldmann A, Borchers P, Katalinic A
BMC Cancer 2023 Dec 1;23(1):1180. doi: 10.1186/s12885-023-11660-1. PMID: 38041106Free PMC Article
Surgical treatment of stage IV gastroenteropancreatic neuroendocrine carcinoma: Experience and outcomes in the United States.
Kerekes D, Frey A, Bakkila B, Kunstman JW, Khan SA
J Surg Oncol 2023 Oct;128(5):790-802. Epub 2023 Jul 12 doi: 10.1002/jso.27392. PMID: 37435780
Impact of Patient Comorbidities on Presentation Stage of Breast and Colon Cancers.
Sharon CE, Wang M, Tortorello GN, Perry NJ, Ma KL, Tchou JC, Fayanju OM, Mahmoud NN, Miura JT, Karakousis GC
Ann Surg Oncol 2023 Aug;30(8):4617-4626. Epub 2023 May 19 doi: 10.1245/s10434-023-13596-z. PMID: 37208570Free PMC Article
Association Between Survival and Metastatic Site in Mismatch Repair-Deficient Metastatic Colorectal Cancer Treated With First-line Pembrolizumab.
Saberzadeh-Ardestani B, Jones JC, Hubbard JM, McWilliams RR, Halfdanarson TR, Shi Q, Sonbol MB, Ticku J, Jin Z, Sinicrope FA
JAMA Netw Open 2023 Feb 1;6(2):e230400. doi: 10.1001/jamanetworkopen.2023.0400. PMID: 36811859Free PMC Article
A nine-gene signature to improve prognosis prediction of colon carcinoma.
Zhao J, Wang Y, Gao J, Wang Y, Zhong X, Wu X, Li H
Cell Cycle 2021 May;20(10):1021-1032. Epub 2021 May 14 doi: 10.1080/15384101.2021.1919827. PMID: 33985413Free PMC Article

Recent systematic reviews

Factors predicting postoperative morbidity after cytoreductive surgery for ovarian cancer: a systematic review and meta-analysis.
Kengsakul M, Nieuwenhuyzen-de Boer GM, Udomkarnjananun S, Kerr SJ, Niehot CD, van Beekhuizen HJ
J Gynecol Oncol 2022 Jul;33(4):e53. Epub 2022 Jun 7 doi: 10.3802/jgo.2022.33.e53. PMID: 35712967Free PMC Article
Mixed adenoneuroendocrine carcinoma (MANEC) of the lower gastrointestinal tract: A systematic review with Bayesian hierarchical survival analysis.
Grossi U, Bonis A, Carrington EV, Mazzobel E, Santoro GA, Cattaneo L, Centonze G, Gallo G, Kazemi Nava A, Romano M, Di Tanna GL, Zanus G
Eur J Surg Oncol 2021 Nov;47(11):2893-2899. Epub 2021 May 14 doi: 10.1016/j.ejso.2021.05.021. PMID: 34052038
Thrombocytosis Portends Adverse Prognosis in Colorectal Cancer: A Meta-Analysis of 5,619 Patients in 16 Individual Studies.
Gu D, Szallasi A
Anticancer Res 2017 Sep;37(9):4717-4726. doi: 10.21873/anticanres.11878. PMID: 28870890
Complete mesocolic excision an assessment of feasibility and outcome.
Bertelsen CA
Dan Med J 2017 Feb;64(2) PMID: 28157065
Mucinous subtype as prognostic factor in colorectal cancer: a systematic review and meta-analysis.
Verhulst J, Ferdinande L, Demetter P, Ceelen W
J Clin Pathol 2012 May;65(5):381-8. Epub 2012 Jan 18 doi: 10.1136/jclinpath-2011-200340. PMID: 22259177

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