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Diffuse pulmonary fibrosis

MedGen UID:
167847
•Concept ID:
C0865849
•
Disease or Syndrome
Synonyms: Diffuse Pulmonary Fibrosis; diffuse pulmonary fibrosis
 
Monarch Initiative: MONDO:0003563

Definition

Diffuse replacement of the lung tissue by connective tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiffuse pulmonary fibrosis

Professional guidelines

PubMed

Natural products as home-based prophylactic and symptom management agents in the setting of COVID-19.
Thota SM, Balan V, Sivaramakrishnan V
Phytother Res 2020 Dec;34(12):3148-3167. Epub 2020 Aug 17 doi: 10.1002/ptr.6794. PMID: 32881214Free PMC Article
Pathology of asbestosis- An update of the diagnostic criteria: Report of the asbestosis committee of the college of american pathologists and pulmonary pathology society.
Roggli VL, Gibbs AR, Attanoos R, Churg A, Popper H, Cagle P, Corrin B, Franks TJ, Galateau-Salle F, Galvin J, Hasleton PS, Henderson DW, Honma K
Arch Pathol Lab Med 2010 Mar;134(3):462-80. doi: 10.5858/134.3.462. PMID: 20196674
Idiopathic pulmonary fibrosis: current and future treatment options.
Davies HR, Richeldi L
Am J Respir Med 2002;1(3):211-24. doi: 10.1007/BF03256611. PMID: 14720059

Recent clinical studies

Etiology

The effect of diffuse pulmonary fibrosis on the reliability of CT signs of pulmonary hypertension.
Devaraj A, Wells AU, Meister MG, Corte TJ, Hansell DM
Radiology 2008 Dec;249(3):1042-9. doi: 10.1148/radiol.2492080269. PMID: 19011195
Association of malignancy with diseases causing interstitial pulmonary changes.
Bouros D, Hatzakis K, Labrakis H, Zeibecoglou K
Chest 2002 Apr;121(4):1278-89. doi: 10.1378/chest.121.4.1278. PMID: 11948064
Idiopathic pulmonary fibrosis and malignancy.
Ma Y, Seneviratne CK, Koss M
Curr Opin Pulm Med 2001 Sep;7(5):278-82. doi: 10.1097/00063198-200109000-00005. PMID: 11584176
Cigarette smoke, asbestos, and small irregular opacities.
Weiss W
Am Rev Respir Dis 1984 Aug;130(2):293-301. doi: 10.1164/arrd.1984.130.2.293. PMID: 6380358
Thromboxane and prostacyclin (epoprostenol) during exercise in diffuse pulmonary fibrosis.
Risk C, Rie M, Peterson M, Kong D, Woods B, Watkins WD
Lancet 1982 Nov 27;2(8309):1183-5. doi: 10.1016/s0140-6736(82)91202-8. PMID: 6128494

Diagnosis

The emerging role of epigenetic regulation in the progression of silicosis.
Yin H, Xie Y, Gu P, Li W, Zhang Y, Yao Y, Chen W, Ma J
Clin Epigenetics 2022 Dec 9;14(1):169. doi: 10.1186/s13148-022-01391-8. PMID: 36494831Free PMC Article
Dust induces lung fibrosis through dysregulated DNA methylation.
Zhang N, Liu K, Wang K, Zhou C, Wang H, Che S, Liu Z, Yang H
Environ Toxicol 2019 Jun;34(6):728-741. Epub 2019 Feb 28 doi: 10.1002/tox.22739. PMID: 30815999
Idiopathic pulmonary fibrosis: current and future treatment options.
Davies HR, Richeldi L
Am J Respir Med 2002;1(3):211-24. doi: 10.1007/BF03256611. PMID: 14720059
Idiopathic pulmonary fibrosis and malignancy.
Ma Y, Seneviratne CK, Koss M
Curr Opin Pulm Med 2001 Sep;7(5):278-82. doi: 10.1097/00063198-200109000-00005. PMID: 11584176
Diffuse pulmonary fibrosis and hiatus hernia.
Pearson JE, Wilson RS
Thorax 1971 May;26(3):300-5. doi: 10.1136/thx.26.3.300. PMID: 5089496Free PMC Article

Therapy

Dust induces lung fibrosis through dysregulated DNA methylation.
Zhang N, Liu K, Wang K, Zhou C, Wang H, Che S, Liu Z, Yang H
Environ Toxicol 2019 Jun;34(6):728-741. Epub 2019 Feb 28 doi: 10.1002/tox.22739. PMID: 30815999
Idiopathic pulmonary fibrosis: current and future treatment options.
Davies HR, Richeldi L
Am J Respir Med 2002;1(3):211-24. doi: 10.1007/BF03256611. PMID: 14720059
Cigarette smoke, asbestos, and small irregular opacities.
Weiss W
Am Rev Respir Dis 1984 Aug;130(2):293-301. doi: 10.1164/arrd.1984.130.2.293. PMID: 6380358
Desquamative interstitial pneumonia: relationship to interstitial fibrosis.
Patchefsky AS, Israel HL, Hoch WS, Gordon G
Thorax 1973 Nov;28(6):680-93. doi: 10.1136/thx.28.6.680. PMID: 4595813Free PMC Article
The treatment of pulmonary emphysema and of diffuse pulmonary fibrosis with nebulized bronchodilators and intermittent positive pressure breathing.
MILLER RD, FOWLER WS, HELMHOLZ HF Jr
Dis Chest 1955 Sep;28(3):309-25. doi: 10.1378/chest.28.3.309. PMID: 13251090

Prognosis

The emerging role of epigenetic regulation in the progression of silicosis.
Yin H, Xie Y, Gu P, Li W, Zhang Y, Yao Y, Chen W, Ma J
Clin Epigenetics 2022 Dec 9;14(1):169. doi: 10.1186/s13148-022-01391-8. PMID: 36494831Free PMC Article
Increasing incidence of lung transplantation in patients with post-COVID-19 pulmonary fibrosis.
Khajotia R
Pan Afr Med J 2021;40:169. Epub 2021 Nov 18 doi: 10.11604/pamj.2021.40.169.31223. PMID: 34970411Free PMC Article
Relationship between diffuse pulmonary fibrosis, alveolar proteinosis, and granulocyte-macrophage colony stimulating factor autoantibodies.
Luisetti M, Bruno P, Kadija Z, Suzuki T, Raffa S, Torrisi MR, Campo I, Mariani F, Pozzi E, Trapnell BC, Mariotta S
Respir Care 2011 Oct;56(10):1608-10. Epub 2011 Apr 19 doi: 10.4187/respcare.01054. PMID: 21513605
Idiopathic pulmonary fibrosis and malignancy.
Ma Y, Seneviratne CK, Koss M
Curr Opin Pulm Med 2001 Sep;7(5):278-82. doi: 10.1097/00063198-200109000-00005. PMID: 11584176
Diffuse pulmonary fibrosis and hiatus hernia.
Pearson JE, Wilson RS
Thorax 1971 May;26(3):300-5. doi: 10.1136/thx.26.3.300. PMID: 5089496Free PMC Article

Clinical prediction guides

The emerging role of epigenetic regulation in the progression of silicosis.
Yin H, Xie Y, Gu P, Li W, Zhang Y, Yao Y, Chen W, Ma J
Clin Epigenetics 2022 Dec 9;14(1):169. doi: 10.1186/s13148-022-01391-8. PMID: 36494831Free PMC Article
Increasing incidence of lung transplantation in patients with post-COVID-19 pulmonary fibrosis.
Khajotia R
Pan Afr Med J 2021;40:169. Epub 2021 Nov 18 doi: 10.11604/pamj.2021.40.169.31223. PMID: 34970411Free PMC Article
The effect of diffuse pulmonary fibrosis on the reliability of CT signs of pulmonary hypertension.
Devaraj A, Wells AU, Meister MG, Corte TJ, Hansell DM
Radiology 2008 Dec;249(3):1042-9. doi: 10.1148/radiol.2492080269. PMID: 19011195
Different patterns of gas exchange response to exercise in asbestosis and idiopathic pulmonary fibrosis.
Agusti AG, Roca J, Rodriguez-Roisin R, Xaubet A, Agusti-Vidal A
Eur Respir J 1988 Jun;1(6):510-6. PMID: 3169220
Desquamative interstitial pneumonia: relationship to interstitial fibrosis.
Patchefsky AS, Israel HL, Hoch WS, Gordon G
Thorax 1973 Nov;28(6):680-93. doi: 10.1136/thx.28.6.680. PMID: 4595813Free PMC Article

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