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Metastatic Extracranial Malignant Solid Neoplasm

MedGen UID:
1679584
•Concept ID:
C4763549
•
Neoplastic Process
Synonym: Metastatic Extracranial Malignant Solid Tumor

Definition

A malignant solid neoplasm that arises from any anatomic site other than the brain and has spread from its original site of growth to another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Extracranial Malignant Solid Neoplasm

Professional guidelines

PubMed

Current Status and Future Perspective on Molecular Imaging and Treatment of Neuroblastoma.
Feng L, Li S, Wang C, Yang J
Semin Nucl Med 2023 Jul;53(4):517-529. Epub 2023 Jan 21 doi: 10.1053/j.semnuclmed.2022.12.004. PMID: 36682980
Neuroblastoma: clinical and biological approach to risk stratification and treatment.
Tolbert VP, Matthay KK
Cell Tissue Res 2018 May;372(2):195-209. Epub 2018 Mar 23 doi: 10.1007/s00441-018-2821-2. PMID: 29572647Free PMC Article
Updates in Diagnosis, Management, and Treatment of Neuroblastoma.
Swift CC, Eklund MJ, Kraveka JM, Alazraki AL
Radiographics 2018 Mar-Apr;38(2):566-580. doi: 10.1148/rg.2018170132. PMID: 29528815

Recent clinical studies

Etiology

Efficacy and safety of first-line lorlatinib versus crizotinib in patients with advanced, ALK-positive non-small-cell lung cancer: updated analysis of data from the phase 3, randomised, open-label CROWN study.
Solomon BJ, Bauer TM, Mok TSK, Liu G, Mazieres J, de Marinis F, Goto Y, Kim DW, Wu YL, Jassem J, López FL, Soo RA, Shaw AT, Polli A, Messina R, Iadeluca L, Toffalorio F, Felip E
Lancet Respir Med 2023 Apr;11(4):354-366. Epub 2022 Dec 16 doi: 10.1016/S2213-2600(22)00437-4. PMID: 36535300
Role and toxicity of radiation therapy in neuroblastoma patients: A literature review.
Zhao Q, Liu Y, Zhang Y, Meng L, Wei J, Wang B, Wang H, Xin Y, Dong L, Jiang X
Crit Rev Oncol Hematol 2020 May;149:102924. Epub 2020 Mar 3 doi: 10.1016/j.critrevonc.2020.102924. PMID: 32172225
Lazertinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: results from the dose escalation and dose expansion parts of a first-in-human, open-label, multicentre, phase 1-2 study.
Ahn MJ, Han JY, Lee KH, Kim SW, Kim DW, Lee YG, Cho EK, Kim JH, Lee GW, Lee JS, Min YJ, Kim JS, Lee SS, Kim HR, Hong MH, Ahn JS, Sun JM, Kim HT, Lee DH, Kim S, Cho BC
Lancet Oncol 2019 Dec;20(12):1681-1690. Epub 2019 Oct 3 doi: 10.1016/S1470-2045(19)30504-2. PMID: 31587882
Updates in Diagnosis, Management, and Treatment of Neuroblastoma.
Swift CC, Eklund MJ, Kraveka JM, Alazraki AL
Radiographics 2018 Mar-Apr;38(2):566-580. doi: 10.1148/rg.2018170132. PMID: 29528815
Neuroblastoma.
Matthay KK, Maris JM, Schleiermacher G, Nakagawara A, Mackall CL, Diller L, Weiss WA
Nat Rev Dis Primers 2016 Nov 10;2:16078. doi: 10.1038/nrdp.2016.78. PMID: 27830764

Diagnosis

Where Are We Now and Where Might We Be Headed in Understanding and Managing Brain Metastases in Colorectal Cancer Patients?
Mjahed RB, Astaras C, Roth A, Koessler T
Curr Treat Options Oncol 2022 Jul;23(7):980-1000. Epub 2022 Apr 28 doi: 10.1007/s11864-022-00982-0. PMID: 35482170Free PMC Article
Updates in Diagnosis, Management, and Treatment of Neuroblastoma.
Swift CC, Eklund MJ, Kraveka JM, Alazraki AL
Radiographics 2018 Mar-Apr;38(2):566-580. doi: 10.1148/rg.2018170132. PMID: 29528815
Neuroblastoma.
Matthay KK, Maris JM, Schleiermacher G, Nakagawara A, Mackall CL, Diller L, Weiss WA
Nat Rev Dis Primers 2016 Nov 10;2:16078. doi: 10.1038/nrdp.2016.78. PMID: 27830764
Management of neoplastic meningitis.
Roth P, Weller M
Chin Clin Oncol 2015 Jun;4(2):26. doi: 10.3978/j.issn.2304-3865.2015.05.02. PMID: 26112812
Rhabdomyosarcoma: an overview.
Dagher R, Helman L
Oncologist 1999;4(1):34-44. PMID: 10337369

Therapy

The Role of Ketogenic Diet in the Treatment of Neuroblastoma.
Makuku R, Sinaei Far Z, Khalili N, Moyo A, Razi S, Keshavarz-Fathi M, Mahmoudi M, Rezaei N
Integr Cancer Ther 2023 Jan-Dec;22:15347354221150787. doi: 10.1177/15347354221150787. PMID: 36752115Free PMC Article
Efficacy and safety of first-line lorlatinib versus crizotinib in patients with advanced, ALK-positive non-small-cell lung cancer: updated analysis of data from the phase 3, randomised, open-label CROWN study.
Solomon BJ, Bauer TM, Mok TSK, Liu G, Mazieres J, de Marinis F, Goto Y, Kim DW, Wu YL, Jassem J, López FL, Soo RA, Shaw AT, Polli A, Messina R, Iadeluca L, Toffalorio F, Felip E
Lancet Respir Med 2023 Apr;11(4):354-366. Epub 2022 Dec 16 doi: 10.1016/S2213-2600(22)00437-4. PMID: 36535300
Lazertinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: results from the dose escalation and dose expansion parts of a first-in-human, open-label, multicentre, phase 1-2 study.
Ahn MJ, Han JY, Lee KH, Kim SW, Kim DW, Lee YG, Cho EK, Kim JH, Lee GW, Lee JS, Min YJ, Kim JS, Lee SS, Kim HR, Hong MH, Ahn JS, Sun JM, Kim HT, Lee DH, Kim S, Cho BC
Lancet Oncol 2019 Dec;20(12):1681-1690. Epub 2019 Oct 3 doi: 10.1016/S1470-2045(19)30504-2. PMID: 31587882
Promising therapeutic targets in neuroblastoma.
Matthay KK, George RE, Yu AL
Clin Cancer Res 2012 May 15;18(10):2740-53. doi: 10.1158/1078-0432.CCR-11-1939. PMID: 22589483Free PMC Article
Brain metastasis in pediatric extracranial solid tumors: survey and literature review.
Kebudi R, Ayan I, Görgün O, Ağaoğlu FY, Vural S, Darendeliler E
J Neurooncol 2005 Jan;71(1):43-8. doi: 10.1007/s11060-004-4840-y. PMID: 15719274

Prognosis

Lazertinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: results from the dose escalation and dose expansion parts of a first-in-human, open-label, multicentre, phase 1-2 study.
Ahn MJ, Han JY, Lee KH, Kim SW, Kim DW, Lee YG, Cho EK, Kim JH, Lee GW, Lee JS, Min YJ, Kim JS, Lee SS, Kim HR, Hong MH, Ahn JS, Sun JM, Kim HT, Lee DH, Kim S, Cho BC
Lancet Oncol 2019 Dec;20(12):1681-1690. Epub 2019 Oct 3 doi: 10.1016/S1470-2045(19)30504-2. PMID: 31587882
Updates in Diagnosis, Management, and Treatment of Neuroblastoma.
Swift CC, Eklund MJ, Kraveka JM, Alazraki AL
Radiographics 2018 Mar-Apr;38(2):566-580. doi: 10.1148/rg.2018170132. PMID: 29528815
Neuroblastoma.
Matthay KK, Maris JM, Schleiermacher G, Nakagawara A, Mackall CL, Diller L, Weiss WA
Nat Rev Dis Primers 2016 Nov 10;2:16078. doi: 10.1038/nrdp.2016.78. PMID: 27830764
Management of neoplastic meningitis.
Roth P, Weller M
Chin Clin Oncol 2015 Jun;4(2):26. doi: 10.3978/j.issn.2304-3865.2015.05.02. PMID: 26112812
Rhabdomyosarcoma: an overview.
Dagher R, Helman L
Oncologist 1999;4(1):34-44. PMID: 10337369

Clinical prediction guides

Efficacy and safety of first-line lorlatinib versus crizotinib in patients with advanced, ALK-positive non-small-cell lung cancer: updated analysis of data from the phase 3, randomised, open-label CROWN study.
Solomon BJ, Bauer TM, Mok TSK, Liu G, Mazieres J, de Marinis F, Goto Y, Kim DW, Wu YL, Jassem J, López FL, Soo RA, Shaw AT, Polli A, Messina R, Iadeluca L, Toffalorio F, Felip E
Lancet Respir Med 2023 Apr;11(4):354-366. Epub 2022 Dec 16 doi: 10.1016/S2213-2600(22)00437-4. PMID: 36535300
The Significance of Histopathologic Assessment in Bone Marrow Disease in Neuroblastoma.
Ekmekci S, Ince D, Olgun N, Ozer E
Turk Patoloji Derg 2022;38(2):99-105. doi: 10.5146/tjpath.2021.01556. PMID: 34558657Free PMC Article
Advances in the systemic treatment of melanoma brain metastases.
Glitza Oliva IC, Schvartsman G, Tawbi H
Ann Oncol 2018 Jul 1;29(7):1509-1520. doi: 10.1093/annonc/mdy185. PMID: 29790899
Neuroblastoma: clinical and biological approach to risk stratification and treatment.
Tolbert VP, Matthay KK
Cell Tissue Res 2018 May;372(2):195-209. Epub 2018 Mar 23 doi: 10.1007/s00441-018-2821-2. PMID: 29572647Free PMC Article
Management of neoplastic meningitis.
Roth P, Weller M
Chin Clin Oncol 2015 Jun;4(2):26. doi: 10.3978/j.issn.2304-3865.2015.05.02. PMID: 26112812

Recent systematic reviews

Effectiveness and safety of "real" concurrent stereotactic radiotherapy and immunotherapy in metastatic solid tumors: a systematic review.
Trapani S, Manicone M, Sikokis A, D'Abbiero N, Salaroli F, Ceccon G, Buti S
Crit Rev Oncol Hematol 2019 Oct;142:9-15. Epub 2019 Jul 11 doi: 10.1016/j.critrevonc.2019.07.006. PMID: 31325712
123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma.
Bleeker G, Tytgat GA, Adam JA, Caron HN, Kremer LC, Hooft L, van Dalen EC
Cochrane Database Syst Rev 2015 Sep 29;2015(9):CD009263. doi: 10.1002/14651858.CD009263.pub2. PMID: 26417712Free PMC Article
Integration of chemotherapy into current treatment strategies for brain metastases from solid tumors.
Nieder C, Grosu AL, Astner S, Thamm R, Molls M
Radiat Oncol 2006 Jun 27;1:19. doi: 10.1186/1748-717X-1-19. PMID: 16800900Free PMC Article

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