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Overactive bladder

MedGen UID:
168058
Concept ID:
C0878773
Disease or Syndrome
Synonym: Overactive bladder (disease)
SNOMED CT: Hypertonic bladder (9009001); Instability of bladder (786457000); Bladder instability (786457000); Overactive bladder (786457000); Hyperactive bladder (786457000)
 
Monarch Initiative: MONDO:0006624

Definition

Symptom of overactive detrusor muscle of the urinary bladder that contracts with abnormally high frequency and urgency. Overactive bladder is characterized by the frequent feeling of needing to urinate during the day, during the night, or both. urinary incontinence may or may not be present. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOveractive bladder

Professional guidelines

PubMed

Quaghebeur J, Petros P, Wyndaele JJ, De Wachter S
Eur J Obstet Gynecol Reprod Biol 2021 Oct;265:143-149. Epub 2021 Aug 28 doi: 10.1016/j.ejogrb.2021.08.026. PMID: 34492609
Weiss JP, Everaert K
Urology 2019 Nov;133S:24-33. Epub 2019 Oct 2 doi: 10.1016/j.urology.2019.09.022. PMID: 31586470
Haid B, Tekgül S
Eur Urol Focus 2017 Apr;3(2-3):198-206. Epub 2017 Sep 6 doi: 10.1016/j.euf.2017.08.010. PMID: 28888814

Recent clinical studies

Etiology

Xiao Y, Yin S, Wang J, Cui J, Yang Z, Wang J, Bai Y
Front Public Health 2023;11:1137191. Epub 2023 Aug 10 doi: 10.3389/fpubh.2023.1137191. PMID: 37637821Free PMC Article
Zillioux J, Slopnick EA, Vasavada SP
Neurourol Urodyn 2022 Nov;41(8):1967-1974. Epub 2022 May 29 doi: 10.1002/nau.24965. PMID: 35645033Free PMC Article
Sonmez R, Yildiz N, Alkan H
Ann Phys Rehabil Med 2022 Jan;65(1):101486. Epub 2021 Nov 11 doi: 10.1016/j.rehab.2021.101486. PMID: 33429090
Chen LC, Kuo HC
Low Urin Tract Symptoms 2020 May;12(2):109-116. Epub 2020 Feb 19 doi: 10.1111/luts.12304. PMID: 32073742
Shaw HA, Burrows LJ
South Med J 2011 Jan;104(1):34-9. doi: 10.1097/SMJ.0b013e3181faec80. PMID: 21079535

Diagnosis

Hutchinson A, Nesbitt A, Joshi A, Clubb A, Perera M
Aust J Gen Pract 2020 Sep;49(9):593-598. doi: 10.31128/AJGP-11-19-5142. PMID: 32864677
Sussman RD, Syan R, Brucker BM
BJU Int 2020 May;125(5):638-655. Epub 2020 Mar 8 doi: 10.1111/bju.14927. PMID: 31625673
Lightner DJ, Gomelsky A, Souter L, Vasavada SP
J Urol 2019 Sep;202(3):558-563. Epub 2019 Aug 8 doi: 10.1097/JU.0000000000000309. PMID: 31039103
Bardsley A
Br J Nurs 2016 Oct 13;25(18):S14-S21. doi: 10.12968/bjon.2016.25.18.S14. PMID: 27734727
White N, Iglesia CB
Obstet Gynecol Clin North Am 2016 Mar;43(1):59-68. doi: 10.1016/j.ogc.2015.10.002. PMID: 26880508

Therapy

He W, Huang G, Cui W, Tian Y, Sun Q, Zhao X, Zhao Y, Li D, Liu X
Int Braz J Urol 2023 Sep-Oct;49(5):535-563. doi: 10.1590/S1677-5538.IBJU.2023.0158. PMID: 37506033Free PMC Article
He W, Zhang Y, Huang G, Tian Y, Sun Q, Liu X
Low Urin Tract Symptoms 2023 May;15(3):80-88. Epub 2023 Mar 2 doi: 10.1111/luts.12475. PMID: 36863312
Bapir R, Bhatti KH, Eliwa A, García-Perdomo HA, Gherabi N, Hennessey D, Magri V, Mourmouris P, Ouattara A, Perletti G, Philipraj J, Stamatiou K, Trinchieri A, Buchholz N
Arch Ital Urol Androl 2022 Dec 28;94(4):492-506. doi: 10.4081/aiua.2022.4.492. PMID: 36576454
Kennelly MJ, Rhodes T, Girman CJ, Thomas E, Shortino D, Mudd PN Jr
Adv Ther 2021 Nov;38(11):5452-5464. Epub 2021 Sep 18 doi: 10.1007/s12325-021-01902-8. PMID: 34537953Free PMC Article
Lightner DJ, Gomelsky A, Souter L, Vasavada SP
J Urol 2019 Sep;202(3):558-563. Epub 2019 Aug 8 doi: 10.1097/JU.0000000000000309. PMID: 31039103

Prognosis

Tunn R, Baessler K, Knüpfer S, Hampel C
Dtsch Arztebl Int 2023 Feb 3;120(5):71-80. doi: 10.3238/arztebl.m2022.0406. PMID: 36647585Free PMC Article
Blomquist JL, Carroll M, Muñoz A, Handa VL
Am J Obstet Gynecol 2020 Jan;222(1):62.e1-62.e8. Epub 2019 Aug 8 doi: 10.1016/j.ajog.2019.08.003. PMID: 31422064
Blomquist JL, Muñoz A, Carroll M, Handa VL
JAMA 2018 Dec 18;320(23):2438-2447. doi: 10.1001/jama.2018.18315. PMID: 30561480Free PMC Article
Suskind AM
Curr Urol Rep 2017 Sep;18(9):67. doi: 10.1007/s11934-017-0720-9. PMID: 28718161Free PMC Article
Bhide AA, Cartwright R, Khullar V, Digesu GA
Int Urogynecol J 2013 Jul;24(7):1065-72. Epub 2013 Jan 12 doi: 10.1007/s00192-012-2027-1. PMID: 23314226

Clinical prediction guides

Meng L, Tian Z, Zhang Y, Wang J, Liao L, Chen G, Tian X, Ma L, Li Y, Shi B, Zhang Y, Ling Q, Zhang P, Wei Z, Zhong T, Xu Z, Li J, Luo D
Sci Rep 2022 Dec 24;12(1):22299. doi: 10.1038/s41598-022-26267-y. PMID: 36566332Free PMC Article
Funada S, Luo Y, Yoshioka T, Setoh K, Tabara Y, Negoro H, Yoshimura K, Matsuda F, Efthimiou O, Ogawa O, Furukawa TA, Kobayashi T, Akamatsu S
Int J Urol 2022 Jul;29(7):748-756. Epub 2022 Apr 7 doi: 10.1111/iju.14887. PMID: 35393696Free PMC Article
Reynolds WS, Kaufman MR, Bruehl S, Dmochowski RR, McKernan LC
Neurourol Urodyn 2022 Jan;41(1):195-202. Epub 2021 Sep 15 doi: 10.1002/nau.24788. PMID: 34524704Free PMC Article
Motegi SI, Sekiguchi A, Sekine Y, Nakayama H, Suzuki K, Ishikawa O
Mod Rheumatol 2020 Mar;30(2):327-331. Epub 2019 Apr 1 doi: 10.1080/14397595.2019.1589913. PMID: 30836050
Yamada S, Ito Y, Nishijima S, Kadekawa K, Sugaya K
Pharmacol Ther 2018 Sep;189:130-148. Epub 2018 Apr 27 doi: 10.1016/j.pharmthera.2018.04.010. PMID: 29709423

Recent systematic reviews

He W, Huang G, Cui W, Tian Y, Sun Q, Zhao X, Zhao Y, Li D, Liu X
Int Braz J Urol 2023 Sep-Oct;49(5):535-563. doi: 10.1590/S1677-5538.IBJU.2023.0158. PMID: 37506033Free PMC Article
He W, Zhang Y, Huang G, Tian Y, Sun Q, Liu X
Low Urin Tract Symptoms 2023 May;15(3):80-88. Epub 2023 Mar 2 doi: 10.1111/luts.12475. PMID: 36863312
Bapir R, Bhatti KH, Eliwa A, García-Perdomo HA, Gherabi N, Hennessey D, Magri V, Mourmouris P, Ouattara A, Perletti G, Philipraj J, Stamatiou K, Trinchieri A, Buchholz N
Arch Ital Urol Androl 2022 Dec 28;94(4):492-506. doi: 10.4081/aiua.2022.4.492. PMID: 36576454
Nambiar AK, Arlandis S, Bø K, Cobussen-Boekhorst H, Costantini E, de Heide M, Farag F, Groen J, Karavitakis M, Lapitan MC, Manso M, Arteaga SM, Riogh ANA, O'Connor E, Omar MI, Peyronnet B, Phé V, Sakalis VI, Sihra N, Tzelves L, van Poelgeest-Pomfret ML, van den Bos TWL, van der Vaart H, Harding CK
Eur Urol 2022 Jul;82(1):49-59. Epub 2022 Feb 23 doi: 10.1016/j.eururo.2022.01.045. PMID: 35216856
Kennelly MJ, Rhodes T, Girman CJ, Thomas E, Shortino D, Mudd PN Jr
Adv Ther 2021 Nov;38(11):5452-5464. Epub 2021 Sep 18 doi: 10.1007/s12325-021-01902-8. PMID: 34537953Free PMC Article

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