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Unresectable Lymphoma

MedGen UID:
1680878
•Concept ID:
C4763776
•
Neoplastic Process

Definition

Lymphoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Lymphoma

Professional guidelines

PubMed

Clinical recommendations for diagnosis and treatment according to current updated knowledge on BIA-ALCL.
Longo B, Di Napoli A, Curigliano G, Veronesi P, Pileri S, Martelli M, De Vita R, Felici N, Cirillo P, Bernardi C, D'orsi G, Giacalone M, Storti G, Cervelli V
Breast 2022 Dec;66:332-341. Epub 2022 Dec 3 doi: 10.1016/j.breast.2022.11.009. PMID: 36502569Free PMC Article
Immunotherapy Alone or in Combination with Chemotherapy as First-Line Treatment of Non-Small Cell Lung Cancer.
Saxena P, Singh PK, Malik PS, Singh N
Curr Treat Options Oncol 2020 Jul 27;21(8):69. doi: 10.1007/s11864-020-00768-2. PMID: 32720019
Systemic treatment options for radiation-associated sarcomas.
Dickson MA
Curr Treat Options Oncol 2014 Sep;15(3):476-81. doi: 10.1007/s11864-014-0299-z. PMID: 24968875

Recent clinical studies

Etiology

Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children's Oncology Group Study.
Mossé YP, Voss SD, Lim MS, Rolland D, Minard CG, Fox E, Adamson P, Wilner K, Blaney SM, Weigel BJ
J Clin Oncol 2017 Oct 1;35(28):3215-3221. Epub 2017 Aug 8 doi: 10.1200/JCO.2017.73.4830. PMID: 28787259Free PMC Article
Anaplastic lymphoma kinase-directed therapy in inflammatory myofibroblastic tumors.
Tothova Z, Wagner AJ
Curr Opin Oncol 2012 Jul;24(4):409-13. doi: 10.1097/CCO.0b013e328354c155. PMID: 22664824
Diagnosis of esophagogastric tumors.
Moretó M
Endoscopy 2003 Jan;35(1):36-42. doi: 10.1055/s-2003-36398. PMID: 12510224
Rare pulmonary neoplasms.
Miller DL, Allen MS
Mayo Clin Proc 1993 May;68(5):492-8. doi: 10.1016/s0025-6196(12)60199-2. PMID: 8386792

Diagnosis

Inflammatory myofibroblastic tumor: molecular landscape, targeted therapeutics, and remaining challenges.
Mahajan P, Casanova M, Ferrari A, Fordham A, Trahair T, Venkatramani R
Curr Probl Cancer 2021 Aug;45(4):100768. Epub 2021 Jul 1 doi: 10.1016/j.currproblcancer.2021.100768. PMID: 34244015
Immunotherapy Alone or in Combination with Chemotherapy as First-Line Treatment of Non-Small Cell Lung Cancer.
Saxena P, Singh PK, Malik PS, Singh N
Curr Treat Options Oncol 2020 Jul 27;21(8):69. doi: 10.1007/s11864-020-00768-2. PMID: 32720019
Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children's Oncology Group Study.
Mossé YP, Voss SD, Lim MS, Rolland D, Minard CG, Fox E, Adamson P, Wilner K, Blaney SM, Weigel BJ
J Clin Oncol 2017 Oct 1;35(28):3215-3221. Epub 2017 Aug 8 doi: 10.1200/JCO.2017.73.4830. PMID: 28787259Free PMC Article
Diagnosis of esophagogastric tumors.
Moretó M
Endoscopy 2003 Jan;35(1):36-42. doi: 10.1055/s-2003-36398. PMID: 12510224

Therapy

T-cell-engaging bispecific antibodies in cancer.
van de Donk NWCJ, Zweegman S
Lancet 2023 Jul 8;402(10396):142-158. Epub 2023 Jun 1 doi: 10.1016/S0140-6736(23)00521-4. PMID: 37271153
Tremelimumab: First Approval.
Keam SJ
Drugs 2023 Jan;83(1):93-102. doi: 10.1007/s40265-022-01827-8. PMID: 36571670
Inflammatory myofibroblastic tumor: molecular landscape, targeted therapeutics, and remaining challenges.
Mahajan P, Casanova M, Ferrari A, Fordham A, Trahair T, Venkatramani R
Curr Probl Cancer 2021 Aug;45(4):100768. Epub 2021 Jul 1 doi: 10.1016/j.currproblcancer.2021.100768. PMID: 34244015
Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children's Oncology Group Study.
Mossé YP, Voss SD, Lim MS, Rolland D, Minard CG, Fox E, Adamson P, Wilner K, Blaney SM, Weigel BJ
J Clin Oncol 2017 Oct 1;35(28):3215-3221. Epub 2017 Aug 8 doi: 10.1200/JCO.2017.73.4830. PMID: 28787259Free PMC Article
Pembrolizumab (Keytruda).
Kwok G, Yau TC, Chiu JW, Tse E, Kwong YL
Hum Vaccin Immunother 2016 Nov;12(11):2777-2789. Epub 2016 Jul 11 doi: 10.1080/21645515.2016.1199310. PMID: 27398650Free PMC Article

Prognosis

Multisystem ALK-positive histiocytosis: a multi-case study and literature review.
Liu W, Liu HJ, Wang WY, Tang Y, Zhao S, Zhang WY, Yan JQ, Liu WP
Orphanet J Rare Dis 2023 Mar 13;18(1):53. doi: 10.1186/s13023-023-02649-x. PMID: 36915094Free PMC Article
Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Chemotherapy for advanced non-small cell lung cancer with a focus on squamous cell carcinoma.
Kuribayashi K, Funaguchi N, Nakano T
J Cancer Res Ther 2016 Apr-Jun;12(2):528-34. doi: 10.4103/0973-1482.174185. PMID: 27461605
Pembrolizumab (Keytruda).
Kwok G, Yau TC, Chiu JW, Tse E, Kwong YL
Hum Vaccin Immunother 2016 Nov;12(11):2777-2789. Epub 2016 Jul 11 doi: 10.1080/21645515.2016.1199310. PMID: 27398650Free PMC Article
Diagnosis of esophagogastric tumors.
Moretó M
Endoscopy 2003 Jan;35(1):36-42. doi: 10.1055/s-2003-36398. PMID: 12510224

Clinical prediction guides

Multisystem ALK-positive histiocytosis: a multi-case study and literature review.
Liu W, Liu HJ, Wang WY, Tang Y, Zhao S, Zhang WY, Yan JQ, Liu WP
Orphanet J Rare Dis 2023 Mar 13;18(1):53. doi: 10.1186/s13023-023-02649-x. PMID: 36915094Free PMC Article
Neoadjuvant chemoradiotherapy in patients with unresectable locally advanced sigmoid colon cancer: clinical feasibility and outcome.
Niu SQ, Li RZ, Yuan Y, Xie WH, Wang QX, Chang H, Lu ZH, Ding PR, Li LR, Wu XJ, Zeng ZF, Xiao WW, Gao YH
Radiat Oncol 2021 May 24;16(1):93. doi: 10.1186/s13014-021-01823-4. PMID: 34030722Free PMC Article
Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children's Oncology Group Study.
Mossé YP, Voss SD, Lim MS, Rolland D, Minard CG, Fox E, Adamson P, Wilner K, Blaney SM, Weigel BJ
J Clin Oncol 2017 Oct 1;35(28):3215-3221. Epub 2017 Aug 8 doi: 10.1200/JCO.2017.73.4830. PMID: 28787259Free PMC Article
Pembrolizumab (Keytruda).
Kwok G, Yau TC, Chiu JW, Tse E, Kwong YL
Hum Vaccin Immunother 2016 Nov;12(11):2777-2789. Epub 2016 Jul 11 doi: 10.1080/21645515.2016.1199310. PMID: 27398650Free PMC Article
Diagnosis of esophagogastric tumors.
Moretó M
Endoscopy 2003 Jan;35(1):36-42. doi: 10.1055/s-2003-36398. PMID: 12510224

Recent systematic reviews

Radiotherapy in the management of rare gastrointestinal cancers: A systematic review.
Bellefkih FZ, Benchakroun N, Lalya I, Amaoui B, El Kacemi H, Acharki A, El Hfid M, El Mazghi A, Chekrine T, Bouchbika Z, Jouhadi H, Sahraoui S, Tawfiq N, Michalet M
Cancer Radiother 2023 Sep;27(6-7):622-637. Epub 2023 Jul 25 doi: 10.1016/j.canrad.2023.06.010. PMID: 37500390

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