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T-cell non-Hodgkin lymphoma, subcutaneous

MedGen UID:
1681617
•Concept ID:
C5195175
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVT-cell non-Hodgkin lymphoma, subcutaneous

Professional guidelines

PubMed

Diagnosis and management of cutaneous lymphomas and lymphoid proliferations in children, adolescents and young adults (CAYA).
Stokke J, Tann A, El-Mallawany NK, Oschlies I
Best Pract Res Clin Haematol 2023 Mar;36(1):101448. Epub 2023 Feb 10 doi: 10.1016/j.beha.2023.101448. PMID: 36907638
Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part II: Prognosis and management.
Oh Y, Stoll JR, Moskowitz A, Pulitzer M, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1093-1106. Epub 2021 May 1 doi: 10.1016/j.jaad.2021.04.081. PMID: 33945836
Biology and management of rare primary extranodal T-cell lymphomas.
Roschewski M, Wilson WH
Oncology (Williston Park) 2010 Jan;24(1):94-100. PMID: 20187328Free PMC Article

Recent clinical studies

Etiology

Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part II: Prognosis and management.
Oh Y, Stoll JR, Moskowitz A, Pulitzer M, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1093-1106. Epub 2021 May 1 doi: 10.1016/j.jaad.2021.04.081. PMID: 33945836
Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
Synergistic effect of ibrutinib and CD19 CAR-T cells on Raji cells in vivo and in vitro.
Liu M, Wang X, Li Z, Zhang R, Mu J, Jiang Y, Deng Q, Sun L
Cancer Sci 2020 Nov;111(11):4051-4060. Epub 2020 Sep 15 doi: 10.1111/cas.14638. PMID: 32876369Free PMC Article
Interventions for mycosis fungoides.
Valipour A, Jäger M, Wu P, Schmitt J, Bunch C, Weberschock T
Cochrane Database Syst Rev 2020 Jul 7;7(7):CD008946. doi: 10.1002/14651858.CD008946.pub3. PMID: 32632956Free PMC Article
MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells.
Zheng Z, Sun R, Zhao HJ, Fu D, Zhong HJ, Weng XQ, Qu B, Zhao Y, Wang L, Zhao WL
Mol Cancer 2019 Mar 30;18(1):54. doi: 10.1186/s12943-019-0977-3. PMID: 30925928Free PMC Article

Diagnosis

Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part II: Prognosis and management.
Oh Y, Stoll JR, Moskowitz A, Pulitzer M, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1093-1106. Epub 2021 May 1 doi: 10.1016/j.jaad.2021.04.081. PMID: 33945836
Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
Rare non-Hodgkin lymphoma of childhood and adolescence: A consensus diagnostic and therapeutic approach to pediatric-type follicular lymphoma, marginal zone lymphoma, and nonanaplastic peripheral T-cell lymphoma.
Attarbaschi A, Abla O, Arias Padilla L, Beishuizen A, Burke GAA, Brugières L, Bruneau J, Burkhardt B, d'Amore ESG, Klapper W, Kontny U, Pillon M, Taj M, Turner SD, Uyttebroeck A, Woessmann W, Mellgren K
Pediatr Blood Cancer 2020 Aug;67(8):e28416. Epub 2020 May 26 doi: 10.1002/pbc.28416. PMID: 32452165
MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells.
Zheng Z, Sun R, Zhao HJ, Fu D, Zhong HJ, Weng XQ, Qu B, Zhao Y, Wang L, Zhao WL
Mol Cancer 2019 Mar 30;18(1):54. doi: 10.1186/s12943-019-0977-3. PMID: 30925928Free PMC Article
Cutaneous T-cell lymphoma (CTCL), rare subtypes: five case presentations and review of the literature.
Geller S, Myskowski PL, Pulitzer M, Horwitz SM, Moskowitz AJ
Chin Clin Oncol 2019 Feb;8(1):5. Epub 2018 Nov 21 doi: 10.21037/cco.2018.11.01. PMID: 30525759

Therapy

Non-Hodgkin Lymphoma Developed Shortly after mRNA COVID-19 Vaccination: Report of a Case and Review of the Literature.
Cavanna L, Grassi SO, Ruffini L, Michieletti E, Carella E, Palli D, Zangrandi A, Inzerilli N, Bernuzzi P, Di Nunzio C, Citterio C
Medicina (Kaunas) 2023 Jan 12;59(1) doi: 10.3390/medicina59010157. PMID: 36676781Free PMC Article
Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell-Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II Trial.
Thieblemont C, Phillips T, Ghesquieres H, Cheah CY, Clausen MR, Cunningham D, Do YR, Feldman T, Gasiorowski R, Jurczak W, Kim TM, Lewis DJ, van der Poel M, Poon ML, Cota Stirner M, Kilavuz N, Chiu C, Chen M, Sacchi M, Elliott B, Ahmadi T, Hutchings M, Lugtenburg PJ
J Clin Oncol 2023 Apr 20;41(12):2238-2247. Epub 2022 Dec 22 doi: 10.1200/JCO.22.01725. PMID: 36548927Free PMC Article
Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study.
Hutchings M, Mous R, Clausen MR, Johnson P, Linton KM, Chamuleau MED, Lewis DJ, Sureda Balari A, Cunningham D, Oliveri RS, Elliott B, DeMarco D, Azaryan A, Chiu C, Li T, Chen KM, Ahmadi T, Lugtenburg PJ
Lancet 2021 Sep 25;398(10306):1157-1169. Epub 2021 Sep 8 doi: 10.1016/S0140-6736(21)00889-8. PMID: 34508654
IL-15 in the Combination Immunotherapy of Cancer.
Waldmann TA, Dubois S, Miljkovic MD, Conlon KC
Front Immunol 2020;11:868. Epub 2020 May 19 doi: 10.3389/fimmu.2020.00868. PMID: 32508818Free PMC Article
DuoBody-CD3xCD20 induces potent T-cell-mediated killing of malignant B cells in preclinical models and provides opportunities for subcutaneous dosing.
Engelberts PJ, Hiemstra IH, de Jong B, Schuurhuis DH, Meesters J, Beltran Hernandez I, Oostindie SC, Neijssen J, van den Brink EN, Horbach GJ, Verploegen S, Labrijn AF, Salcedo T, Schuurman J, Parren PWHI, Breij ECW
EBioMedicine 2020 Feb;52:102625. Epub 2020 Jan 23 doi: 10.1016/j.ebiom.2019.102625. PMID: 31981978Free PMC Article

Prognosis

Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part II: Prognosis and management.
Oh Y, Stoll JR, Moskowitz A, Pulitzer M, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1093-1106. Epub 2021 May 1 doi: 10.1016/j.jaad.2021.04.081. PMID: 33945836
Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
MiR155 sensitized B-lymphoma cells to anti-PD-L1 antibody via PD-1/PD-L1-mediated lymphoma cell interaction with CD8+T cells.
Zheng Z, Sun R, Zhao HJ, Fu D, Zhong HJ, Weng XQ, Qu B, Zhao Y, Wang L, Zhao WL
Mol Cancer 2019 Mar 30;18(1):54. doi: 10.1186/s12943-019-0977-3. PMID: 30925928Free PMC Article
Rare Cutaneous T-Cell Lymphomas.
Damasco F, Akilov OE
Hematol Oncol Clin North Am 2019 Feb;33(1):135-148. doi: 10.1016/j.hoc.2018.08.004. PMID: 30497671
Subcutaneous panniculitis-like T-cell lymphoma.
Tomasini D, Berti E
G Ital Dermatol Venereol 2013 Aug;148(4):395-411. PMID: 23900161

Clinical prediction guides

Subcutaneous Panniculitis-Like T-Cell Lymphoma Revealed By Immunophenotyping of Necrosis.
Bellahsen-Harrar Y, Badrignans M, Cherif K, Papouin B, Ingen-Housz-Oro S, Ortonne N
Am J Dermatopathol 2022 Sep 1;44(9):675-676. Epub 2022 Apr 11 doi: 10.1097/DAD.0000000000002203. PMID: 35475979
Tumor cell-derived IL-10 promotes cell-autonomous growth and immune escape in diffuse large B-cell lymphoma.
Stirm K, Leary P, Bertram K, Núñez NG, Wüst D, Boudesco C, Verhoeyen E, Zenz T, Becher B, Menter T, Tzankov A, Müller A
Oncoimmunology 2021;10(1):2003533. Epub 2021 Nov 22 doi: 10.1080/2162402X.2021.2003533. PMID: 34858727Free PMC Article
Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study.
Hutchings M, Mous R, Clausen MR, Johnson P, Linton KM, Chamuleau MED, Lewis DJ, Sureda Balari A, Cunningham D, Oliveri RS, Elliott B, DeMarco D, Azaryan A, Chiu C, Li T, Chen KM, Ahmadi T, Lugtenburg PJ
Lancet 2021 Sep 25;398(10306):1157-1169. Epub 2021 Sep 8 doi: 10.1016/S0140-6736(21)00889-8. PMID: 34508654
Interventions for mycosis fungoides.
Valipour A, Jäger M, Wu P, Schmitt J, Bunch C, Weberschock T
Cochrane Database Syst Rev 2020 Jul 7;7(7):CD008946. doi: 10.1002/14651858.CD008946.pub3. PMID: 32632956Free PMC Article
CD30+ T-cell lymphoproliferative disorders.
Martin JM, Wu H, Barta SK
Chin Clin Oncol 2019 Feb;8(1):4. Epub 2018 Oct 11 doi: 10.21037/cco.2018.09.06. PMID: 30525751

Recent systematic reviews

Diagnosis and Treatment of Subcutaneous Panniculitis-like T-cell Lymphoma: A Systematic Literature Review.
Alsomali DY, Bakshi N, Kharfan-Dabaja M, El Fakih R, Aljurf M
Hematol Oncol Stem Cell Ther 2023 Jan 17;16(2):110-116. doi: 10.1016/j.hemonc.2021.04.001. PMID: 34015273
Eyelid erythema as the first manifestation of subcutaneous panniculitis-like T-cell lymphoma mimicking dermatomyositis: a case-based review.
Sun X, Ji L, Li G, Nong L, Zhang W, Xie W, Zhang Z
Clin Rheumatol 2022 Mar;41(3):929-934. Epub 2021 Nov 16 doi: 10.1007/s10067-021-05992-1. PMID: 34786628
The significance of epidermal involvement in primary cutaneous gamma/delta (γδ) T-cell lymphoma: A systematic review and meta-analysis.
Goyal A, O'Leary D, Duncan LM
J Cutan Pathol 2021 Dec;48(12):1449-1454. Epub 2021 Jul 2 doi: 10.1111/cup.14082. PMID: 34151455
Clinicopathological and prognostic study of primary cutaneous extranodal natural killer/T-cell lymphoma, nasal type: A systematic review.
Jung JM, Yang HJ, Won CH, Chang SE, Lee MW, Lee WJ
J Dermatol 2021 Oct;48(10):1499-1510. Epub 2021 Jun 1 doi: 10.1111/1346-8138.15972. PMID: 34060130
Interventions for mycosis fungoides.
Valipour A, Jäger M, Wu P, Schmitt J, Bunch C, Weberschock T
Cochrane Database Syst Rev 2020 Jul 7;7(7):CD008946. doi: 10.1002/14651858.CD008946.pub3. PMID: 32632956Free PMC Article

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