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T-cell non-Hodgkin lymphoma, subcutaneous

MedGen UID:
1681617
•Concept ID:
C5195175
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVT-cell non-Hodgkin lymphoma, subcutaneous

Professional guidelines

PubMed

Diagnosis and management of cutaneous lymphomas and lymphoid proliferations in children, adolescents and young adults (CAYA).
Stokke J, Tann A, El-Mallawany NK, Oschlies I
Best Pract Res Clin Haematol 2023 Mar;36(1):101448. Epub 2023 Feb 10 doi: 10.1016/j.beha.2023.101448. PMID: 36907638
Diagnosis and Treatment of Subcutaneous Panniculitis-like T-cell Lymphoma: A Systematic Literature Review.
Alsomali DY, Bakshi N, Kharfan-Dabaja M, El Fakih R, Aljurf M
Hematol Oncol Stem Cell Ther 2023 Jan 17;16(2):110-116. doi: 10.1016/j.hemonc.2021.04.001. PMID: 34015273
Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part II: Prognosis and management.
Oh Y, Stoll JR, Moskowitz A, Pulitzer M, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1093-1106. Epub 2021 May 1 doi: 10.1016/j.jaad.2021.04.081. PMID: 33945836

Recent clinical studies

Etiology

Biology and genetics of extranodal mature T-cell and NKcell lymphomas and lymphoproliferative disorders.
Lewis NE, Zhou T, Dogan A
Haematologica 2023 Dec 1;108(12):3261-3277. doi: 10.3324/haematol.2023.282718. PMID: 38037802Free PMC Article
Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
Rare T-Cell Subtypes.
van der Weyden C, McCormack C, Lade S, Johnstone RW, Prince HM
Cancer Treat Res 2019;176:195-224. doi: 10.1007/978-3-319-99716-2_10. PMID: 30596220
CD30+ T-cell lymphoproliferative disorders.
Martin JM, Wu H, Barta SK
Chin Clin Oncol 2019 Feb;8(1):4. Epub 2018 Oct 11 doi: 10.21037/cco.2018.09.06. PMID: 30525751
Subcutaneous panniculitis-like T-cell lymphoma.
Tomasini D, Berti E
G Ital Dermatol Venereol 2013 Aug;148(4):395-411. PMID: 23900161

Diagnosis

Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
Rare T-Cell Subtypes.
van der Weyden C, McCormack C, Lade S, Johnstone RW, Prince HM
Cancer Treat Res 2019;176:195-224. doi: 10.1007/978-3-319-99716-2_10. PMID: 30596220
CD30+ T-cell lymphoproliferative disorders.
Martin JM, Wu H, Barta SK
Chin Clin Oncol 2019 Feb;8(1):4. Epub 2018 Oct 11 doi: 10.21037/cco.2018.09.06. PMID: 30525751
Rare Cutaneous T-Cell Lymphomas.
Damasco F, Akilov OE
Hematol Oncol Clin North Am 2019 Feb;33(1):135-148. doi: 10.1016/j.hoc.2018.08.004. PMID: 30497671
Subcutaneous panniculitis-like T-cell lymphoma.
Tomasini D, Berti E
G Ital Dermatol Venereol 2013 Aug;148(4):395-411. PMID: 23900161

Therapy

Epcoritamab: First Approval.
Frampton JE
Drugs 2023 Sep;83(14):1331-1340. doi: 10.1007/s40265-023-01930-4. PMID: 37597091
CD19 CAR T-cell therapy and prophylactic anakinra in relapsed or refractory lymphoma: phase 2 trial interim results.
Park JH, Nath K, Devlin SM, Sauter CS, Palomba ML, Shah G, Dahi P, Lin RJ, Scordo M, Perales MA, Shouval R, Tomas AA, Cathcart E, Mead E, Santomasso B, Holodny A, Brentjens RJ, Riviere I, Sadelain M
Nat Med 2023 Jul;29(7):1710-1717. Epub 2023 Jul 3 doi: 10.1038/s41591-023-02404-6. PMID: 37400640
Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell-Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II Trial.
Thieblemont C, Phillips T, Ghesquieres H, Cheah CY, Clausen MR, Cunningham D, Do YR, Feldman T, Gasiorowski R, Jurczak W, Kim TM, Lewis DJ, van der Poel M, Poon ML, Cota Stirner M, Kilavuz N, Chiu C, Chen M, Sacchi M, Elliott B, Ahmadi T, Hutchings M, Lugtenburg PJ
J Clin Oncol 2023 Apr 20;41(12):2238-2247. Epub 2022 Dec 22 doi: 10.1200/JCO.22.01725. PMID: 36548927Free PMC Article
Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study.
Hutchings M, Mous R, Clausen MR, Johnson P, Linton KM, Chamuleau MED, Lewis DJ, Sureda Balari A, Cunningham D, Oliveri RS, Elliott B, DeMarco D, Azaryan A, Chiu C, Li T, Chen KM, Ahmadi T, Lugtenburg PJ
Lancet 2021 Sep 25;398(10306):1157-1169. Epub 2021 Sep 8 doi: 10.1016/S0140-6736(21)00889-8. PMID: 34508654
IL-15 in the Combination Immunotherapy of Cancer.
Waldmann TA, Dubois S, Miljkovic MD, Conlon KC
Front Immunol 2020;11:868. Epub 2020 May 19 doi: 10.3389/fimmu.2020.00868. PMID: 32508818Free PMC Article

Prognosis

Biology and genetics of extranodal mature T-cell and NKcell lymphomas and lymphoproliferative disorders.
Lewis NE, Zhou T, Dogan A
Haematologica 2023 Dec 1;108(12):3261-3277. doi: 10.3324/haematol.2023.282718. PMID: 38037802Free PMC Article
Primary cutaneous T-cell lymphomas other than mycosis fungoides and Sézary syndrome. Part I: Clinical and histologic features and diagnosis.
Stoll JR, Willner J, Oh Y, Pulitzer M, Moskowitz A, Horwitz S, Myskowski P, Noor SJ
J Am Acad Dermatol 2021 Nov;85(5):1073-1090. Epub 2021 Apr 30 doi: 10.1016/j.jaad.2021.04.080. PMID: 33940098
Rare Cutaneous T-Cell Lymphomas.
Damasco F, Akilov OE
Hematol Oncol Clin North Am 2019 Feb;33(1):135-148. doi: 10.1016/j.hoc.2018.08.004. PMID: 30497671
Subcutaneous panniculitis-like T-cell lymphoma.
Tomasini D, Berti E
G Ital Dermatol Venereol 2013 Aug;148(4):395-411. PMID: 23900161
Panniculitis in children.
Grassi S, Borroni RG, Brazzelli V
G Ital Dermatol Venereol 2013 Aug;148(4):371-85. PMID: 23900159

Clinical prediction guides

Germline HAVCR2 mutations and their relation to the clinical spectrum of subcutaneous panniculitis-like T-cell lymphoma and hemophagocytic lymphohistiocytosis: results from a multicenter study and meta-analysis.
Moonla C, Polprasert C, Komvilaisak P, Rattanathammethee T, Kongkiatkamon S, Wudhikarn K, Kobbuaklee S, Boonyabaramee P, Tangcheewinsirikul N, Pakakasama S, Rujkijyanont P, Choed-Amphai C, Phuakpet K, Pongudom S, Bunworasate U, Sukswai N, Sosothikul D, Rojnuckarin P
Haematologica 2023 Oct 1;108(10):2743-2752. doi: 10.3324/haematol.2022.282419. PMID: 37051767Free PMC Article
Subcutaneous Panniculitis-Like T-Cell Lymphoma Revealed By Immunophenotyping of Necrosis.
Bellahsen-Harrar Y, Badrignans M, Cherif K, Papouin B, Ingen-Housz-Oro S, Ortonne N
Am J Dermatopathol 2022 Sep 1;44(9):675-676. Epub 2022 Apr 11 doi: 10.1097/DAD.0000000000002203. PMID: 35475979
Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study.
Hutchings M, Mous R, Clausen MR, Johnson P, Linton KM, Chamuleau MED, Lewis DJ, Sureda Balari A, Cunningham D, Oliveri RS, Elliott B, DeMarco D, Azaryan A, Chiu C, Li T, Chen KM, Ahmadi T, Lugtenburg PJ
Lancet 2021 Sep 25;398(10306):1157-1169. Epub 2021 Sep 8 doi: 10.1016/S0140-6736(21)00889-8. PMID: 34508654
CD30+ T-cell lymphoproliferative disorders.
Martin JM, Wu H, Barta SK
Chin Clin Oncol 2019 Feb;8(1):4. Epub 2018 Oct 11 doi: 10.21037/cco.2018.09.06. PMID: 30525751
Subcutaneous lymphoma and related conditions.
Guitart J
Dermatol Ther 2010 Jul-Aug;23(4):350-5. doi: 10.1111/j.1529-8019.2010.01335.x. PMID: 20666822

Recent systematic reviews

Diagnosis and Treatment of Subcutaneous Panniculitis-like T-cell Lymphoma: A Systematic Literature Review.
Alsomali DY, Bakshi N, Kharfan-Dabaja M, El Fakih R, Aljurf M
Hematol Oncol Stem Cell Ther 2023 Jan 17;16(2):110-116. doi: 10.1016/j.hemonc.2021.04.001. PMID: 34015273
Eyelid erythema as the first manifestation of subcutaneous panniculitis-like T-cell lymphoma mimicking dermatomyositis: a case-based review.
Sun X, Ji L, Li G, Nong L, Zhang W, Xie W, Zhang Z
Clin Rheumatol 2022 Mar;41(3):929-934. Epub 2021 Nov 16 doi: 10.1007/s10067-021-05992-1. PMID: 34786628
The significance of epidermal involvement in primary cutaneous gamma/delta (γδ) T-cell lymphoma: A systematic review and meta-analysis.
Goyal A, O'Leary D, Duncan LM
J Cutan Pathol 2021 Dec;48(12):1449-1454. Epub 2021 Jul 2 doi: 10.1111/cup.14082. PMID: 34151455
Clinicopathological and prognostic study of primary cutaneous extranodal natural killer/T-cell lymphoma, nasal type: A systematic review.
Jung JM, Yang HJ, Won CH, Chang SE, Lee MW, Lee WJ
J Dermatol 2021 Oct;48(10):1499-1510. Epub 2021 Jun 1 doi: 10.1111/1346-8138.15972. PMID: 34060130
Interventions for mycosis fungoides.
Valipour A, Jäger M, Wu P, Schmitt J, Bunch C, Weberschock T
Cochrane Database Syst Rev 2020 Jul 7;7(7):CD008946. doi: 10.1002/14651858.CD008946.pub3. PMID: 32632956Free PMC Article

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