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Stage IIIB Cervical Cancer FIGO 2018

MedGen UID:
1685761
•Concept ID:
C5206450
•
Neoplastic Process
Synonym: Stage IIIB Cervical Carcinoma FIGO 2018

Definition

Cervical carcinoma with extension to the pelvic wall and/or hydronephrosis or nonfunctioning kidney (unless known to be due to another cause). (FIGO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage IIIB Cervical Cancer FIGO 2018

Professional guidelines

PubMed

Evaluation of the efficacy of prophylactic extended field irradiation in the concomitant chemoradiotherapy treatment of locally advanced cervical cancer, stage IIIB in the 2018 FIGO classification.
Meng Q, Liu X, Wang W, Hou X, Lian X, Sun S, Yan J, Liu Z, Miao Z, Hu K, Zhang F
Radiat Oncol 2019 Dec 16;14(1):228. doi: 10.1186/s13014-019-1431-9. PMID: 31842919Free PMC Article
HIV status does not have an impact on positron emission tomography-computed tomography (PET-CT) findings or radiotherapy treatment recommendations in patients with locally advanced cervical cancer.
Simonds H, Botha MH, Ellmann A, Warwick J, Doruyter A, Neugut AI, Van Der Merwe H, Jacobson JS
Int J Gynecol Cancer 2019 Oct;29(8):1252-1257. Epub 2019 Aug 13 doi: 10.1136/ijgc-2019-000641. PMID: 31413068
Prognostic Performance of the 2018 International Federation of Gynecology and Obstetrics Cervical Cancer Staging Guidelines.
Wright JD, Matsuo K, Huang Y, Tergas AI, Hou JY, Khoury-Collado F, St Clair CM, Ananth CV, Neugut AI, Hershman DL
Obstet Gynecol 2019 Jul;134(1):49-57. doi: 10.1097/AOG.0000000000003311. PMID: 31188324Free PMC Article

Recent clinical studies

Etiology

Parametrial involvement and decreased survival of women with FIGO stage IIIC1 cervical cancer.
Chang H, Wang M, Liu Y, Wu Y
J Gynecol Oncol 2023 Jul;34(4):e46. Epub 2023 Mar 13 doi: 10.3802/jgo.2023.34.e46. PMID: 36929577Free PMC Article
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Chemoradiation versus radiation alone in stage IIIB cervical cancer patients with or without human immunodeficiency virus.
Grover S, Ning MS, Bale M, Lichter KE, Shah S, Bvochora-Nsingo M, Chiyapo S, Balang D, McGinnis GJ, Ralefala T, Moloi T, Luckett R, Ramogola-Masire D, Robertson ES, Zetola NM
Int J Gynecol Cancer 2021 Sep;31(9):1220-1227. Epub 2021 Jul 26 doi: 10.1136/ijgc-2021-002601. PMID: 34312220Free PMC Article
Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study.
Knoth J, Pötter R, Jürgenliemk-Schulz IM, Haie-Meder C, Fokdal L, Sturdza A, Hoskin P, Mahantshetty U, Segedin B, Bruheim K, Wiebe E, Rai B, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Sundset M, Tan LT, Nout RA, Tanderup K, Kirisits C, Nesvacil N, Lindegaard JC, Schmid MP
Gynecol Oncol 2020 Oct;159(1):136-141. Epub 2020 Aug 11 doi: 10.1016/j.ygyno.2020.07.007. PMID: 32798000
Validation of the 2018 FIGO cervical cancer staging system.
Matsuo K, Machida H, Mandelbaum RS, Konishi I, Mikami M
Gynecol Oncol 2019 Jan;152(1):87-93. Epub 2018 Oct 30 doi: 10.1016/j.ygyno.2018.10.026. PMID: 30389105Free PMC Article

Diagnosis

Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Neoadjuvant chemotherapy in pregnant patients with cervical cancer: a Latin-American multicenter study.
Lopez A, Rodriguez J, Estrada E, Aragona A, Chavez C, Amaro K, De Padua C, Borges Garnica A, Rendón G, Alméciga A, Serrano O, Scasso S, Laufer J, Greif D, Taranto F, Hoegl J, Calderaro di Ruggiero F, Pareja R
Int J Gynecol Cancer 2021 Mar;31(3):468-474. doi: 10.1136/ijgc-2020-001764. PMID: 33649015
Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study.
Knoth J, Pötter R, Jürgenliemk-Schulz IM, Haie-Meder C, Fokdal L, Sturdza A, Hoskin P, Mahantshetty U, Segedin B, Bruheim K, Wiebe E, Rai B, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Sundset M, Tan LT, Nout RA, Tanderup K, Kirisits C, Nesvacil N, Lindegaard JC, Schmid MP
Gynecol Oncol 2020 Oct;159(1):136-141. Epub 2020 Aug 11 doi: 10.1016/j.ygyno.2020.07.007. PMID: 32798000
Prognostic Performance of the 2018 International Federation of Gynecology and Obstetrics Cervical Cancer Staging Guidelines.
Wright JD, Matsuo K, Huang Y, Tergas AI, Hou JY, Khoury-Collado F, St Clair CM, Ananth CV, Neugut AI, Hershman DL
Obstet Gynecol 2019 Jul;134(1):49-57. doi: 10.1097/AOG.0000000000003311. PMID: 31188324Free PMC Article
Postoperative clinicopathological factors affecting cervical adenocarcinoma: Stages I-IIB.
Zhou J, Chen Y, Xu X, Yan D, Lou H
Medicine (Baltimore) 2018 Jan;97(2):e9323. doi: 10.1097/MD.0000000000009323. PMID: 29480826Free PMC Article

Therapy

Prophylactic Extended-Field Irradiation Versus Pelvic Irradiation in Patients With Cervical Cancer With 2018 FIGO Stage IIIC1 Disease.
Wang W, Meng Q, Zhou Y, Hu K, Zhang F, Qiu J, Hou X, Lian X, Yan J, Liu Z, Sun S, Ma J, Liu X
Pract Radiat Oncol 2023 Sep-Oct;13(5):e409-e415. Epub 2023 Apr 17 doi: 10.1016/j.prro.2023.03.010. PMID: 37075837
Chemoradiotherapy in the treatment of cervical cancer - a single institution retrospective review.
Pechačová Z, Lohynská R, Weitoschová Z, Zikán M, Dubová O, Tomancová V, Kmoníčková E, Pála M, Drbohlavová T
Klin Onkol 2022 Spring;35(2):139-149. doi: 10.48095/ccko2022139. PMID: 35459339
Neoadjuvant chemotherapy in pregnant patients with cervical cancer: a Latin-American multicenter study.
Lopez A, Rodriguez J, Estrada E, Aragona A, Chavez C, Amaro K, De Padua C, Borges Garnica A, Rendón G, Alméciga A, Serrano O, Scasso S, Laufer J, Greif D, Taranto F, Hoegl J, Calderaro di Ruggiero F, Pareja R
Int J Gynecol Cancer 2021 Mar;31(3):468-474. doi: 10.1136/ijgc-2020-001764. PMID: 33649015
Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study.
Knoth J, Pötter R, Jürgenliemk-Schulz IM, Haie-Meder C, Fokdal L, Sturdza A, Hoskin P, Mahantshetty U, Segedin B, Bruheim K, Wiebe E, Rai B, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Sundset M, Tan LT, Nout RA, Tanderup K, Kirisits C, Nesvacil N, Lindegaard JC, Schmid MP
Gynecol Oncol 2020 Oct;159(1):136-141. Epub 2020 Aug 11 doi: 10.1016/j.ygyno.2020.07.007. PMID: 32798000
Cisplatin Chemoradiotherapy vs Radiotherapy in FIGO Stage IIIB Squamous Cell Carcinoma of the Uterine Cervix: A Randomized Clinical Trial.
Shrivastava S, Mahantshetty U, Engineer R, Chopra S, Hawaldar R, Hande V, Kerkar RA, Maheshwari A, Shylasree TS, Ghosh J, Bajpai J, Gurram L, Gulia S, Gupta S; Gynecologic Disease Management Group
JAMA Oncol 2018 Apr 1;4(4):506-513. doi: 10.1001/jamaoncol.2017.5179. PMID: 29423520Free PMC Article

Prognosis

Parametrial involvement and decreased survival of women with FIGO stage IIIC1 cervical cancer.
Chang H, Wang M, Liu Y, Wu Y
J Gynecol Oncol 2023 Jul;34(4):e46. Epub 2023 Mar 13 doi: 10.3802/jgo.2023.34.e46. PMID: 36929577Free PMC Article
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study.
Knoth J, Pötter R, Jürgenliemk-Schulz IM, Haie-Meder C, Fokdal L, Sturdza A, Hoskin P, Mahantshetty U, Segedin B, Bruheim K, Wiebe E, Rai B, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Sundset M, Tan LT, Nout RA, Tanderup K, Kirisits C, Nesvacil N, Lindegaard JC, Schmid MP
Gynecol Oncol 2020 Oct;159(1):136-141. Epub 2020 Aug 11 doi: 10.1016/j.ygyno.2020.07.007. PMID: 32798000
FIGO Classification 2018: Validation Study in Patients With Locally Advanced Cervix Cancer Treated With Chemoradiation.
Raut A, Chopra S, Mittal P, Patil G, Mahantshetty U, Gurram L, Swamidas J, Ghosh J, Gulia S, Popat P, Deodhar K, Maheshwari A, Gupta S
Int J Radiat Oncol Biol Phys 2020 Dec 1;108(5):1248-1256. Epub 2020 Jul 15 doi: 10.1016/j.ijrobp.2020.07.020. PMID: 32681859
Evaluation of the efficacy of prophylactic extended field irradiation in the concomitant chemoradiotherapy treatment of locally advanced cervical cancer, stage IIIB in the 2018 FIGO classification.
Meng Q, Liu X, Wang W, Hou X, Lian X, Sun S, Yan J, Liu Z, Miao Z, Hu K, Zhang F
Radiat Oncol 2019 Dec 16;14(1):228. doi: 10.1186/s13014-019-1431-9. PMID: 31842919Free PMC Article

Clinical prediction guides

Chemoradiotherapy in the treatment of cervical cancer - a single institution retrospective review.
Pechačová Z, Lohynská R, Weitoschová Z, Zikán M, Dubová O, Tomancová V, Kmoníčková E, Pála M, Drbohlavová T
Klin Onkol 2022 Spring;35(2):139-149. doi: 10.48095/ccko2022139. PMID: 35459339
Prognostic value of the 2018 FIGO staging system for cervical cancer.
Mohamud A, Høgdall C, Schnack T
Gynecol Oncol 2022 Jun;165(3):506-513. Epub 2022 Mar 26 doi: 10.1016/j.ygyno.2022.02.017. PMID: 35346512
Chemoradiation versus radiation alone in stage IIIB cervical cancer patients with or without human immunodeficiency virus.
Grover S, Ning MS, Bale M, Lichter KE, Shah S, Bvochora-Nsingo M, Chiyapo S, Balang D, McGinnis GJ, Ralefala T, Moloi T, Luckett R, Ramogola-Masire D, Robertson ES, Zetola NM
Int J Gynecol Cancer 2021 Sep;31(9):1220-1227. Epub 2021 Jul 26 doi: 10.1136/ijgc-2021-002601. PMID: 34312220Free PMC Article
Clinical and imaging findings in cervical cancer and their impact on FIGO and TNM staging - An analysis from the EMBRACE study.
Knoth J, Pötter R, Jürgenliemk-Schulz IM, Haie-Meder C, Fokdal L, Sturdza A, Hoskin P, Mahantshetty U, Segedin B, Bruheim K, Wiebe E, Rai B, Cooper R, van der Steen-Banasik E, van Limbergen E, Pieters BR, Sundset M, Tan LT, Nout RA, Tanderup K, Kirisits C, Nesvacil N, Lindegaard JC, Schmid MP
Gynecol Oncol 2020 Oct;159(1):136-141. Epub 2020 Aug 11 doi: 10.1016/j.ygyno.2020.07.007. PMID: 32798000
Evaluation of the efficacy of prophylactic extended field irradiation in the concomitant chemoradiotherapy treatment of locally advanced cervical cancer, stage IIIB in the 2018 FIGO classification.
Meng Q, Liu X, Wang W, Hou X, Lian X, Sun S, Yan J, Liu Z, Miao Z, Hu K, Zhang F
Radiat Oncol 2019 Dec 16;14(1):228. doi: 10.1186/s13014-019-1431-9. PMID: 31842919Free PMC Article

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