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Abnormal circulating gastrin concentration

MedGen UID:
1685975
•Concept ID:
C5139563
•
Finding
Synonym: Abnormal circulating gastrin level
 
HPO: HP:0500166

Definition

An abnormal concentration of gastrin in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal circulating gastrin concentration

Recent clinical studies

Etiology

Plasma Progastrin-Releasing Peptide and Chromogranin A Assays for Diagnosing and Monitoring Lung Well-Differentiated Neuroendocrine Tumors: A Brief Report.
Nisman B, Oleinikov K, Nechushtan H, Maimon O, Atlan K, Peled N, Gross D, Peretz T, Meirovitz A, Grozinsky-Glasberg S
J Thorac Oncol 2023 Mar;18(3):369-376. Epub 2022 Dec 9 doi: 10.1016/j.jtho.2022.11.021. PMID: 36503175
Molecular forms of gastrin in the circulation of patients with achlorhydria.
Ardill JE, Banerjee S, Beattie A, Fillmore D, El Nujumi A, McColl KE
Eur J Gastroenterol Hepatol 1999 Jun;11(6):661-7. doi: 10.1097/00042737-199906000-00013. PMID: 10418939
Helicobacter pylori infection and exaggerated gastrin release. Effects of inflammation and progastrin processing.
Graham DY, Go MF, Lew GM, Genta RM, Rehfeld JF
Scand J Gastroenterol 1993 Aug;28(8):690-4. doi: 10.3109/00365529309098274. PMID: 8210984
Hypochlorhydria and hypergastrinemia and their association with gastrointestinal bleeding in undialyzed and hemodialyzed patients.
Muto S, Asano Y, Hosoda S, Miyata M
Nephron 1988;50(1):10-3. doi: 10.1159/000185109. PMID: 3262834
Plasma concentrations of cholecystokinin in patients with duodenal ulcer disease.
Fried GM, Ogden WD, Fagan CJ, Inoue K, Greeley G, Thompson JC
Surgery 1984 Jan;95(1):27-33. PMID: 6691183

Diagnosis

Plasma Progastrin-Releasing Peptide and Chromogranin A Assays for Diagnosing and Monitoring Lung Well-Differentiated Neuroendocrine Tumors: A Brief Report.
Nisman B, Oleinikov K, Nechushtan H, Maimon O, Atlan K, Peled N, Gross D, Peretz T, Meirovitz A, Grozinsky-Glasberg S
J Thorac Oncol 2023 Mar;18(3):369-376. Epub 2022 Dec 9 doi: 10.1016/j.jtho.2022.11.021. PMID: 36503175
Plasma concentrations of cholecystokinin in patients with duodenal ulcer disease.
Fried GM, Ogden WD, Fagan CJ, Inoue K, Greeley G, Thompson JC
Surgery 1984 Jan;95(1):27-33. PMID: 6691183
The role of gastrin in duodenal ulcer.
McGuigan JE, Harty RF, Maico DG
Trans Am Clin Climatol Assoc 1981;92:199-207. PMID: 6116307Free PMC Article

Therapy

Helicobacter pylori infection and exaggerated gastrin release. Effects of inflammation and progastrin processing.
Graham DY, Go MF, Lew GM, Genta RM, Rehfeld JF
Scand J Gastroenterol 1993 Aug;28(8):690-4. doi: 10.3109/00365529309098274. PMID: 8210984

Prognosis

Plasma Progastrin-Releasing Peptide and Chromogranin A Assays for Diagnosing and Monitoring Lung Well-Differentiated Neuroendocrine Tumors: A Brief Report.
Nisman B, Oleinikov K, Nechushtan H, Maimon O, Atlan K, Peled N, Gross D, Peretz T, Meirovitz A, Grozinsky-Glasberg S
J Thorac Oncol 2023 Mar;18(3):369-376. Epub 2022 Dec 9 doi: 10.1016/j.jtho.2022.11.021. PMID: 36503175
Variations in the release of the NH2-terminal fragment of gastrin-17 in the course of duodenal ulcer disease.
Petersen B, Steen J, Christiansen J
Scand J Gastroenterol 1983 Nov;18(8):1101-7. doi: 10.3109/00365528309181848. PMID: 6673082

Clinical prediction guides

Interrelationships between circulating gastrin and iron status in mice and humans.
Kovac S, Smith K, Anderson GJ, Burgess JR, Shulkes A, Baldwin GS
Am J Physiol Gastrointest Liver Physiol 2008 Oct;295(4):G855-61. Epub 2008 Aug 28 doi: 10.1152/ajpgi.90359.2008. PMID: 18755804Free PMC Article

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