U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Prolonged reptilase time

MedGen UID:
1687820
Concept ID:
C5209275
Finding
HPO: HP:0020193

Definition

An abnormally increased duration of the reptilase time. Reptilase time is a functional plasma clotting assay, which is based on the enzymatic activity of batroxobin. By specifically cleaving fibrinogen A from fibrinogen, batroxobin leads to the formation of a stable fibrin clot. The time, starting from the addition of batroxobin to the plasma sample, until clot formation is the reptilase time and is given in seconds. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProlonged reptilase time

Professional guidelines

PubMed

Boey JP, Gallus A
Drugs Aging 2016 Jul;33(7):475-90. doi: 10.1007/s40266-016-0378-x. PMID: 27255713
Tiede A, Scharf RE, Dobbelstein C, Werwitzke S
Hamostaseologie 2015;35(4):311-8. Epub 2015 Jan 7 doi: 10.5482/HAMO-14-11-0064. PMID: 25564260
Alaraj A, Wallace A, Tesoro E, Ruland S, Amin-Hanjani S, Charbel FT, Aletich V
J Neurointerv Surg 2010 Dec;2(4):371-8. Epub 2010 Jul 23 doi: 10.1136/jnis.2010.002840. PMID: 21990651

Recent clinical studies

Etiology

Pengo V, Levi Minzi S, Dal Bo Zanon R, Cappellato G, Farinati F, Girolami A
J Med 1984;15(2):149-60. PMID: 6096471

Diagnosis

Karapetian H
Methods Mol Biol 2013;992:273-7. doi: 10.1007/978-1-62703-339-8_20. PMID: 23546720
Walter S, Stabler S, Lefkowitz JB
Haemophilia 2006 Jul;12(4):393-7. doi: 10.1111/j.1365-2516.2006.01300.x. PMID: 16834739
Tefferi A, Owen BA, Nichols WL, Witzig TE, Owen WG
Blood 1989 Jul;74(1):252-4. PMID: 2752113
Pengo V, Levi Minzi S, Dal Bo Zanon R, Cappellato G, Farinati F, Girolami A
J Med 1984;15(2):149-60. PMID: 6096471

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...