U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mycobacterium abscessus abscessus infection

MedGen UID:
1688588
Concept ID:
C5139150
Disease or Syndrome
HPO: HP:0032130

Definition

Mycobacterium abscessus complex comprises a group of rapidly growing, multidrug-resistant, nontuberculous mycobacteria that are responsible for a wide spectrum of skin and soft tissue diseases, central nervous system infections, bacteremia, and ocular and other infections. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMycobacterium abscessus abscessus infection

Professional guidelines

PubMed

Baker AW, Maziarz EK, Lewis SS, Stout JE, Anderson DJ, Smith PK, Schroder JN, Daneshmand MA, Alexander BD, Wallace RJ, Sexton DJ, Wolfe CR
Clin Infect Dis 2021 Apr 8;72(7):1232-1240. doi: 10.1093/cid/ciaa215. PMID: 32133489Free PMC Article
Chen B, Song H, Xu M, Gao Q, Wang F, Wang J, Wu J
Surg Infect (Larchmt) 2020 Sep;21(7):639-644. Epub 2020 Jan 9 doi: 10.1089/sur.2019.270. PMID: 31916926
Novosad SA, Beekmann SE, Polgreen PM, Mackey K, Winthrop KL; M. abscessus Study Team
Emerg Infect Dis 2016 Mar;22(3):511-4. doi: 10.3201/eid2203.150828. PMID: 26890211Free PMC Article

Recent clinical studies

Etiology

Lange C, Böttger EC, Cambau E, Griffith DE, Guglielmetti L, van Ingen J, Knight SL, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, Wagner D, Winthrop K, Daley CL; expert panel group for management recommendations in non-tuberculous mycobacterial pulmonary diseases
Lancet Infect Dis 2022 Jul;22(7):e178-e190. Epub 2022 Jan 25 doi: 10.1016/S1473-3099(21)00586-7. PMID: 35090639
Tan S, Kasperbauer S
Semin Respir Crit Care Med 2021 Aug;42(4):567-586. Epub 2021 Jul 14 doi: 10.1055/s-0041-1730997. PMID: 34261181
Franco-Paredes C, Marcos LA, Henao-Martínez AF, Rodríguez-Morales AJ, Villamil-Gómez WE, Gotuzzo E, Bonifaz A
Clin Microbiol Rev 2018 Jan;32(1) Epub 2018 Nov 14 doi: 10.1128/CMR.00069-18. PMID: 30429139Free PMC Article
Koh WJ
Microbiol Spectr 2017 Jan;5(1) doi: 10.1128/microbiolspec.TNMI7-0024-2016. PMID: 28128073
Henkle E, Winthrop KL
Clin Chest Med 2015 Mar;36(1):91-9. Epub 2014 Dec 23 doi: 10.1016/j.ccm.2014.11.002. PMID: 25676522Free PMC Article

Diagnosis

Daley CL, Iaccarino JM, Lange C, Cambau E, Wallace RJ Jr, Andrejak C, Böttger EC, Brozek J, Griffith DE, Guglielmetti L, Huitt GA, Knight SL, Leitman P, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, van Ingen J, Wagner D, Winthrop KL
Eur Respir J 2020 Jul;56(1) Epub 2020 Jul 7 doi: 10.1183/13993003.00535-2020. PMID: 32636299Free PMC Article
Daley CL, Iaccarino JM, Lange C, Cambau E, Wallace RJ Jr, Andrejak C, Böttger EC, Brozek J, Griffith DE, Guglielmetti L, Huitt GA, Knight SL, Leitman P, Marras TK, Olivier KN, Santin M, Stout JE, Tortoli E, van Ingen J, Wagner D, Winthrop KL
Clin Infect Dis 2020 Aug 14;71(4):e1-e36. doi: 10.1093/cid/ciaa241. PMID: 32628747Free PMC Article
Koh WJ
Microbiol Spectr 2017 Jan;5(1) doi: 10.1128/microbiolspec.TNMI7-0024-2016. PMID: 28128073
Porvaznik I, Solovič I, Mokrý J
Adv Exp Med Biol 2017;944:19-25. doi: 10.1007/5584_2016_45. PMID: 27826888
Gonzalez-Santiago TM, Drage LA
Dermatol Clin 2015 Jul;33(3):563-77. Epub 2015 May 8 doi: 10.1016/j.det.2015.03.017. PMID: 26143432

Therapy

Nick JA, Dedrick RM, Gray AL, Vladar EK, Smith BE, Freeman KG, Malcolm KC, Epperson LE, Hasan NA, Hendrix J, Callahan K, Walton K, Vestal B, Wheeler E, Rysavy NM, Poch K, Caceres S, Lovell VK, Hisert KB, de Moura VC, Chatterjee D, De P, Weakly N, Martiniano SL, Lynch DA, Daley CL, Strong M, Jia F, Hatfull GF, Davidson RM
Cell 2022 May 26;185(11):1860-1874.e12. Epub 2022 May 13 doi: 10.1016/j.cell.2022.04.024. PMID: 35568033Free PMC Article
Griffith DE, Daley CL
Chest 2022 Jan;161(1):64-75. Epub 2021 Jul 24 doi: 10.1016/j.chest.2021.07.035. PMID: 34314673
Johansen MD, Herrmann JL, Kremer L
Nat Rev Microbiol 2020 Jul;18(7):392-407. Epub 2020 Feb 21 doi: 10.1038/s41579-020-0331-1. PMID: 32086501
Koh WJ
Microbiol Spectr 2017 Jan;5(1) doi: 10.1128/microbiolspec.TNMI7-0024-2016. PMID: 28128073
Henkle E, Winthrop KL
Clin Chest Med 2015 Mar;36(1):91-9. Epub 2014 Dec 23 doi: 10.1016/j.ccm.2014.11.002. PMID: 25676522Free PMC Article

Prognosis

Nick JA, Dedrick RM, Gray AL, Vladar EK, Smith BE, Freeman KG, Malcolm KC, Epperson LE, Hasan NA, Hendrix J, Callahan K, Walton K, Vestal B, Wheeler E, Rysavy NM, Poch K, Caceres S, Lovell VK, Hisert KB, de Moura VC, Chatterjee D, De P, Weakly N, Martiniano SL, Lynch DA, Daley CL, Strong M, Jia F, Hatfull GF, Davidson RM
Cell 2022 May 26;185(11):1860-1874.e12. Epub 2022 May 13 doi: 10.1016/j.cell.2022.04.024. PMID: 35568033Free PMC Article
Griffith DE, Daley CL
Chest 2022 Jan;161(1):64-75. Epub 2021 Jul 24 doi: 10.1016/j.chest.2021.07.035. PMID: 34314673
Cowman S, van Ingen J, Griffith DE, Loebinger MR
Eur Respir J 2019 Jul;54(1) Epub 2019 Jul 11 doi: 10.1183/13993003.00250-2019. PMID: 31221809
Máiz Carro L, Barbero Herranz E, Nieto Royo R
Med Clin (Barc) 2018 Mar 9;150(5):191-197. Epub 2017 Sep 18 doi: 10.1016/j.medcli.2017.07.010. PMID: 28923675
Porvaznik I, Solovič I, Mokrý J
Adv Exp Med Biol 2017;944:19-25. doi: 10.1007/5584_2016_45. PMID: 27826888

Clinical prediction guides

Dedrick RM, Smith BE, Cristinziano M, Freeman KG, Jacobs-Sera D, Belessis Y, Whitney Brown A, Cohen KA, Davidson RM, van Duin D, Gainey A, Garcia CB, Robert George CR, Haidar G, Ip W, Iredell J, Khatami A, Little JS, Malmivaara K, McMullan BJ, Michalik DE, Moscatelli A, Nick JA, Tupayachi Ortiz MG, Polenakovik HM, Robinson PD, Skurnik M, Solomon DA, Soothill J, Spencer H, Wark P, Worth A, Schooley RT, Benson CA, Hatfull GF
Clin Infect Dis 2023 Jan 6;76(1):103-112. doi: 10.1093/cid/ciac453. PMID: 35676823Free PMC Article
Nick JA, Dedrick RM, Gray AL, Vladar EK, Smith BE, Freeman KG, Malcolm KC, Epperson LE, Hasan NA, Hendrix J, Callahan K, Walton K, Vestal B, Wheeler E, Rysavy NM, Poch K, Caceres S, Lovell VK, Hisert KB, de Moura VC, Chatterjee D, De P, Weakly N, Martiniano SL, Lynch DA, Daley CL, Strong M, Jia F, Hatfull GF, Davidson RM
Cell 2022 May 26;185(11):1860-1874.e12. Epub 2022 May 13 doi: 10.1016/j.cell.2022.04.024. PMID: 35568033Free PMC Article
Griffith DE, Daley CL
Chest 2022 Jan;161(1):64-75. Epub 2021 Jul 24 doi: 10.1016/j.chest.2021.07.035. PMID: 34314673
Kumar C, Shrivastava K, Singh A, Chauhan V, Varma-Basil M
Int J Mycobacteriol 2021 Jul-Sep;10(3):293-300. doi: 10.4103/ijmy.ijmy_110_21. PMID: 34494569
Bryant JM, Brown KP, Burbaud S, Everall I, Belardinelli JM, Rodriguez-Rincon D, Grogono DM, Peterson CM, Verma D, Evans IE, Ruis C, Weimann A, Arora D, Malhotra S, Bannerman B, Passemar C, Templeton K, MacGregor G, Jiwa K, Fisher AJ, Blundell TL, Ordway DJ, Jackson M, Parkhill J, Floto RA
Science 2021 Apr 30;372(6541) doi: 10.1126/science.abb8699. PMID: 33926925Free PMC Article

Recent systematic reviews

van Gemert JP, Ravensbergen SJ, Verschuuren EAM, Kerstjens HAM, Willemse BWM, van Ingen J, Hoefsloot W, Gan T, Akkerman OW
Transplant Rev (Orlando) 2023 Dec;37(4):100800. Epub 2023 Oct 7 doi: 10.1016/j.trre.2023.100800. PMID: 37832509
Andersson V, Fröberg G, Dahl VN, Chryssanthou E, Giske C, Schön T, Forsman LD
Int J Mycobacteriol 2023 Jul-Sep;12(3):211-225. doi: 10.4103/ijmy.ijmy_131_23. PMID: 37721224
Dahl VN, Mølhave M, Fløe A, van Ingen J, Schön T, Lillebaek T, Andersen AB, Wejse C
Int J Infect Dis 2022 Dec;125:120-131. Epub 2022 Oct 13 doi: 10.1016/j.ijid.2022.10.013. PMID: 36244600
Manders J, Leow T, van Aerde K, Hol M, Kunst D, Pegge S, Jansen T, van Ingen J, Bekkers S
Int J Infect Dis 2022 Mar;116:397-402. Epub 2022 Jan 14 doi: 10.1016/j.ijid.2022.01.017. PMID: 35038600
Waters V, Ratjen F
Cochrane Database Syst Rev 2016 Dec 19;12(12):CD010004. doi: 10.1002/14651858.CD010004.pub4. PMID: 28000919Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...