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Testicular Plasmacytoma

MedGen UID:
1689279
•Concept ID:
C5206580
•
Neoplastic Process

Definition

A rare plasmacytoma that arises in the testis. At presentation the involvement is usually unilateral. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTesticular Plasmacytoma

Professional guidelines

PubMed

Multiple myeloma with IGH-FGFR3 rearrangement progressing as testicular plasmacytoma during carfilzomib treatment.
Nakamura N, Maruyama D, Maeshima AM, Saito Y, Fujino T, Ito Y, Hatta S, Makita S, Fukuhara S, Munakata W, Suzuki T, Fujimoto H, Izutsu K
Ann Hematol 2019 Oct;98(10):2463-2465. Epub 2019 Jun 25 doi: 10.1007/s00277-019-03743-6. PMID: 31240468

Recent clinical studies

Etiology

Late Relapse of Multiple Myeloma with Testicular Plasmacytoma after Autologous Hematopoietic Stem Cell Transplantation: A Case Report and Review of the Literature.
Wei ZL, Pan CM, Jiang YZ, Yan-Dai, Huanguang LQ, Huang DP
Ann Clin Lab Sci 2018 Jan;48(1):120-125. PMID: 29531008

Diagnosis

Testicular plasmacytoma misdiagnosed as orchitis.
Schiavo C, Mann SA, Mer J, Suvannasankha A
BMJ Case Rep 2018 Jun 4;2018 doi: 10.1136/bcr-2017-222046. PMID: 29866662Free PMC Article
Late Relapse of Multiple Myeloma with Testicular Plasmacytoma after Autologous Hematopoietic Stem Cell Transplantation: A Case Report and Review of the Literature.
Wei ZL, Pan CM, Jiang YZ, Yan-Dai, Huanguang LQ, Huang DP
Ann Clin Lab Sci 2018 Jan;48(1):120-125. PMID: 29531008
Testicular plasmacytoma, an unusal testicular tumor.
Roels P, Mattelaere P, Claikens B
JBR-BTR 2014 Mar-Apr;97(2):115-7. doi: 10.5334/jbr-btr.33. PMID: 25073246
Testicular plasmacytoma as presentation of multiple myeloma: case report and review of the literature.
Pow Sang M, Astigueta JC, Abad M, Sánchez J, León J
Arch Esp Urol 2013 Mar;66(2):242-8. PMID: 23589604
Primary testicular plasmacytoma with hydrocele of the testis.
Suzuki K, Shioji Y, Morita T, Tokue A
Int J Urol 2001 Mar;8(3):139-40. doi: 10.1046/j.1442-2042.2001.00269.x. PMID: 11260342

Therapy

Testicular plasmacytoma misdiagnosed as orchitis.
Schiavo C, Mann SA, Mer J, Suvannasankha A
BMJ Case Rep 2018 Jun 4;2018 doi: 10.1136/bcr-2017-222046. PMID: 29866662Free PMC Article
Late Relapse of Multiple Myeloma with Testicular Plasmacytoma after Autologous Hematopoietic Stem Cell Transplantation: A Case Report and Review of the Literature.
Wei ZL, Pan CM, Jiang YZ, Yan-Dai, Huanguang LQ, Huang DP
Ann Clin Lab Sci 2018 Jan;48(1):120-125. PMID: 29531008
Primary plasma cell leukemia followed by testicular plasmacytoma.
Valentini CG, Bozzoli V, Fianchi L, Voso MT, Di Paolantonio G, Criscuolo M, Leone G, Larocca LM, Pagano L
Int J Hematol 2011 Feb;93(2):224-227. Epub 2011 Jan 13 doi: 10.1007/s12185-010-0745-z. PMID: 21229400
An unusual presentation of extramedullary plasmacytoma in testis and review of the literature.
Turk HM, Komurcu S, Ozet A, Kuzhan O, Günhan O
Med Oncol 2010 Dec;27(4):1378-80. Epub 2009 Dec 25 doi: 10.1007/s12032-009-9390-x. PMID: 20035386
Testicular plasmacytoma with bone dissemination without medullary plasmacytosis.
Hou TY, Dai MS, Kao WY
Ann Hematol 2003 Aug;82(8):518-520. Epub 2003 Jun 28 doi: 10.1007/s00277-003-0672-7. PMID: 12838369

Prognosis

Late Relapse of Multiple Myeloma with Testicular Plasmacytoma after Autologous Hematopoietic Stem Cell Transplantation: A Case Report and Review of the Literature.
Wei ZL, Pan CM, Jiang YZ, Yan-Dai, Huanguang LQ, Huang DP
Ann Clin Lab Sci 2018 Jan;48(1):120-125. PMID: 29531008
Testicular plasmacytoma as presentation of multiple myeloma: case report and review of the literature.
Pow Sang M, Astigueta JC, Abad M, Sánchez J, León J
Arch Esp Urol 2013 Mar;66(2):242-8. PMID: 23589604
Primary plasma cell leukemia followed by testicular plasmacytoma.
Valentini CG, Bozzoli V, Fianchi L, Voso MT, Di Paolantonio G, Criscuolo M, Leone G, Larocca LM, Pagano L
Int J Hematol 2011 Feb;93(2):224-227. Epub 2011 Jan 13 doi: 10.1007/s12185-010-0745-z. PMID: 21229400
An unusual presentation of extramedullary plasmacytoma in testis and review of the literature.
Turk HM, Komurcu S, Ozet A, Kuzhan O, Günhan O
Med Oncol 2010 Dec;27(4):1378-80. Epub 2009 Dec 25 doi: 10.1007/s12032-009-9390-x. PMID: 20035386
Multiple myeloma: a patient with unusual features including intracranial and meningeal involvement, testicular involvement, organomegaly, and plasma cell leukemia.
Turhal N, Henehan MD, Kaplan KL
Am J Hematol 1998 Jan;57(1):51-6. doi: 10.1002/(sici)1096-8652(199801)57:1<51::aid-ajh9>3.0.co;2-0. PMID: 9423817

Clinical prediction guides

Testicular plasmacytoma following chemical orchiectomy: potential role of hypogonadism in myeloma proliferation.
Kahr WH, Al-Homadhi A, Meharchand J, Bailey DJ, Stewart AK
Leuk Lymphoma 1998 Jan;28(3-4):437-42. PMID: 9517517

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