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Flaky paint dermatosis

MedGen UID:
1690071
•Concept ID:
C5139175
•
Disease or Syndrome
Synonym: Flaky paint skin appearance
 
HPO: HP:0032178

Definition

A dermatosis characterized by generalized shiny, enamel-like, hyperpigmented scales in an irregular pattern. The scales may peel or desquamate, rather like old, sun-baked blistered paint, often with areas of underlying hypopigmentation. This has led to the terms peeling paint or flaky paint dermatosis (See the Figure in PMID:24285001). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFlaky paint dermatosis

Recent clinical studies

Etiology

Dermatological changes in a prospective cohort of acutely ill, hospitalised Malawian children, stratified according to nutritional status.
van den Brink D, Mponda K, Thompson D, van Hees C, Ngong'a F, Segula E, Mbale E, Boele van Hensbroek M, Bandsma RHJ, Walson JL, Brals D, Berkely J, Voskuijl W
BMJ Paediatr Open 2024 Jun 8;8(1) doi: 10.1136/bmjpo-2023-002289. PMID: 38851219Free PMC Article
Niacin metabolism and indoleamine 2,3-dioxygenase activation in malnourished patients with flaky paint dermatosis.
Maltos AL, Portari GV, Moraes GV, Monteiro MC, Vannucchi H, da Cunha DF
Nutrition 2015 Jun;31(6):890-2. Epub 2014 Dec 31 doi: 10.1016/j.nut.2014.12.023. PMID: 25933499

Diagnosis

Dermatological changes in a prospective cohort of acutely ill, hospitalised Malawian children, stratified according to nutritional status.
van den Brink D, Mponda K, Thompson D, van Hees C, Ngong'a F, Segula E, Mbale E, Boele van Hensbroek M, Bandsma RHJ, Walson JL, Brals D, Berkely J, Voskuijl W
BMJ Paediatr Open 2024 Jun 8;8(1) doi: 10.1136/bmjpo-2023-002289. PMID: 38851219Free PMC Article
Flaky Paint Dermatosis in Kwashiorkor.
Vijayasankar P, Karthikeyan K
Am J Trop Med Hyg 2021 Oct 4;106(1):3. doi: 10.4269/ajtmh.21-0487. PMID: 34607303Free PMC Article
Flaky paint dermatosis. Kwashiorkor.
Cox JA, Beachkofsky T, Dominguez A
JAMA Dermatol 2014 Jan;150(1):85-6. doi: 10.1001/jamadermatol.2013.5520. PMID: 24285001
The dermatosis of kwashiorkor in young children.
Latham MC
Semin Dermatol 1991 Dec;10(4):270-2. PMID: 1764353

Clinical prediction guides

Dermatological changes in a prospective cohort of acutely ill, hospitalised Malawian children, stratified according to nutritional status.
van den Brink D, Mponda K, Thompson D, van Hees C, Ngong'a F, Segula E, Mbale E, Boele van Hensbroek M, Bandsma RHJ, Walson JL, Brals D, Berkely J, Voskuijl W
BMJ Paediatr Open 2024 Jun 8;8(1) doi: 10.1136/bmjpo-2023-002289. PMID: 38851219Free PMC Article

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