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Locally Advanced Bladder Urothelial Carcinoma

MedGen UID:
1690233
Concept ID:
C5206696
Neoplastic Process

Definition

A bladder urothelial carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Bladder Urothelial Carcinoma

Professional guidelines

PubMed

Shvero A, Hubosky SG
Curr Oncol Rep 2022 May;24(5):611-619. Epub 2022 Feb 25 doi: 10.1007/s11912-021-01179-8. PMID: 35212921
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Sundahl N, Rottey S, De Maeseneer D, Ost P
Expert Rev Anticancer Ther 2018 Feb;18(2):107-114. Epub 2017 Dec 29 doi: 10.1080/14737140.2018.1421461. PMID: 29284318

Recent clinical studies

Etiology

Loriot Y, Matsubara N, Park SH, Huddart RA, Burgess EF, Houede N, Banek S, Guadalupi V, Ku JH, Valderrama BP, Tran B, Triantos S, Kean Y, Akapame S, Deprince K, Mukhopadhyay S, Stone NL, Siefker-Radtke AO; THOR Cohort 1 Investigators
N Engl J Med 2023 Nov 23;389(21):1961-1971. Epub 2023 Oct 21 doi: 10.1056/NEJMoa2308849. PMID: 37870920
Powles T, Csőszi T, Özgüroğlu M, Matsubara N, Géczi L, Cheng SY, Fradet Y, Oudard S, Vulsteke C, Morales Barrera R, Fléchon A, Gunduz S, Loriot Y, Rodriguez-Vida A, Mamtani R, Yu EY, Nam K, Imai K, Homet Moreno B, Alva A; KEYNOTE-361 Investigators
Lancet Oncol 2021 Jul;22(7):931-945. Epub 2021 May 26 doi: 10.1016/S1470-2045(21)00152-2. PMID: 34051178
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Grossman HB, Natale RB, Tangen CM, Speights VO, Vogelzang NJ, Trump DL, deVere White RW, Sarosdy MF, Wood DP Jr, Raghavan D, Crawford ED
N Engl J Med 2003 Aug 28;349(9):859-66. doi: 10.1056/NEJMoa022148. PMID: 12944571
von der Maase H, Hansen SW, Roberts JT, Dogliotti L, Oliver T, Moore MJ, Bodrogi I, Albers P, Knuth A, Lippert CM, Kerbrat P, Sanchez Rovira P, Wersall P, Cleall SP, Roychowdhury DF, Tomlin I, Visseren-Grul CM, Conte PF
J Clin Oncol 2000 Sep;18(17):3068-77. doi: 10.1200/JCO.2000.18.17.3068. PMID: 11001674

Diagnosis

Shvero A, Hubosky SG
Curr Oncol Rep 2022 May;24(5):611-619. Epub 2022 Feb 25 doi: 10.1007/s11912-021-01179-8. PMID: 35212921
Lopez-Beltran A, Cimadamore A, Montironi R, Cheng L
Hum Pathol 2021 Jul;113:67-83. Epub 2021 Apr 19 doi: 10.1016/j.humpath.2021.04.001. PMID: 33887300
Sheng X, Yan X, Wang L, Shi Y, Yao X, Luo H, Shi B, Liu J, He Z, Yu G, Ying J, Han W, Hu C, Ling Y, Chi Z, Cui C, Si L, Fang J, Zhou A, Guo J
Clin Cancer Res 2021 Jan 1;27(1):43-51. Epub 2020 Oct 27 doi: 10.1158/1078-0432.CCR-20-2488. PMID: 33109737
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
Christensen E, Birkenkamp-Demtröder K, Sethi H, Shchegrova S, Salari R, Nordentoft I, Wu HT, Knudsen M, Lamy P, Lindskrog SV, Taber A, Balcioglu M, Vang S, Assaf Z, Sharma S, Tin AS, Srinivasan R, Hafez D, Reinert T, Navarro S, Olson A, Ram R, Dashner S, Rabinowitz M, Billings P, Sigurjonsson S, Andersen CL, Swenerton R, Aleshin A, Zimmermann B, Agerbæk M, Lin CJ, Jensen JB, Dyrskjøt L
J Clin Oncol 2019 Jun 20;37(18):1547-1557. Epub 2019 May 6 doi: 10.1200/JCO.18.02052. PMID: 31059311

Therapy

Loriot Y, Matsubara N, Park SH, Huddart RA, Burgess EF, Houede N, Banek S, Guadalupi V, Ku JH, Valderrama BP, Tran B, Triantos S, Kean Y, Akapame S, Deprince K, Mukhopadhyay S, Stone NL, Siefker-Radtke AO; THOR Cohort 1 Investigators
N Engl J Med 2023 Nov 23;389(21):1961-1971. Epub 2023 Oct 21 doi: 10.1056/NEJMoa2308849. PMID: 37870920
Liang Y, Tan Y, Guan B, Guo B, Xia M, Li J, Shi Y, Yu Z, Zhang Q, Liu D, Yang X, Hao J, Gong Y, Shakeel M, Zhou L, Ci W, Li X
Theranostics 2022;12(18):7745-7759. Epub 2022 Nov 14 doi: 10.7150/thno.77281. PMID: 36451860Free PMC Article
Heath EI, Rosenberg JE
Nat Rev Urol 2021 Feb;18(2):93-103. Epub 2020 Nov 25 doi: 10.1038/s41585-020-00394-5. PMID: 33239713
Grossman HB, Natale RB, Tangen CM, Speights VO, Vogelzang NJ, Trump DL, deVere White RW, Sarosdy MF, Wood DP Jr, Raghavan D, Crawford ED
N Engl J Med 2003 Aug 28;349(9):859-66. doi: 10.1056/NEJMoa022148. PMID: 12944571
von der Maase H, Hansen SW, Roberts JT, Dogliotti L, Oliver T, Moore MJ, Bodrogi I, Albers P, Knuth A, Lippert CM, Kerbrat P, Sanchez Rovira P, Wersall P, Cleall SP, Roychowdhury DF, Tomlin I, Visseren-Grul CM, Conte PF
J Clin Oncol 2000 Sep;18(17):3068-77. doi: 10.1200/JCO.2000.18.17.3068. PMID: 11001674

Prognosis

Liang Y, Tan Y, Guan B, Guo B, Xia M, Li J, Shi Y, Yu Z, Zhang Q, Liu D, Yang X, Hao J, Gong Y, Shakeel M, Zhou L, Ci W, Li X
Theranostics 2022;12(18):7745-7759. Epub 2022 Nov 14 doi: 10.7150/thno.77281. PMID: 36451860Free PMC Article
Siefker-Radtke AO, Necchi A, Park SH, García-Donas J, Huddart RA, Burgess EF, Fleming MT, Rezazadeh Kalebasty A, Mellado B, Varlamov S, Joshi M, Duran I, Tagawa ST, Zakharia Y, Akapame S, Santiago-Walker AE, Monga M, O'Hagan A, Loriot Y; BLC2001 Study Group
Lancet Oncol 2022 Feb;23(2):248-258. Epub 2022 Jan 11 doi: 10.1016/S1470-2045(21)00660-4. PMID: 35030333
Heath EI, Rosenberg JE
Nat Rev Urol 2021 Feb;18(2):93-103. Epub 2020 Nov 25 doi: 10.1038/s41585-020-00394-5. PMID: 33239713
Rouprêt M, Babjuk M, Burger M, Capoun O, Cohen D, Compérat EM, Cowan NC, Dominguez-Escrig JL, Gontero P, Hugh Mostafid A, Palou J, Peyronnet B, Seisen T, Soukup V, Sylvester RJ, Rhijn BWGV, Zigeuner R, Shariat SF
Eur Urol 2021 Jan;79(1):62-79. Epub 2020 Jun 24 doi: 10.1016/j.eururo.2020.05.042. PMID: 32593530
von der Maase H, Hansen SW, Roberts JT, Dogliotti L, Oliver T, Moore MJ, Bodrogi I, Albers P, Knuth A, Lippert CM, Kerbrat P, Sanchez Rovira P, Wersall P, Cleall SP, Roychowdhury DF, Tomlin I, Visseren-Grul CM, Conte PF
J Clin Oncol 2000 Sep;18(17):3068-77. doi: 10.1200/JCO.2000.18.17.3068. PMID: 11001674

Clinical prediction guides

Grivas P, Park SH, Voog E, Caserta C, Gurney H, Bellmunt J, Kalofonos H, Ullén A, Loriot Y, Sridhar SS, Yamamoto Y, Petrylak DP, Sternberg CN, Gupta S, Huang B, Costa N, Laliberte RJ, di Pietro A, Valderrama BP, Powles T
Eur Urol 2023 Jul;84(1):95-108. Epub 2023 Apr 28 doi: 10.1016/j.eururo.2023.03.030. PMID: 37121850
Liang Y, Tan Y, Guan B, Guo B, Xia M, Li J, Shi Y, Yu Z, Zhang Q, Liu D, Yang X, Hao J, Gong Y, Shakeel M, Zhou L, Ci W, Li X
Theranostics 2022;12(18):7745-7759. Epub 2022 Nov 14 doi: 10.7150/thno.77281. PMID: 36451860Free PMC Article
Powles T, Csőszi T, Özgüroğlu M, Matsubara N, Géczi L, Cheng SY, Fradet Y, Oudard S, Vulsteke C, Morales Barrera R, Fléchon A, Gunduz S, Loriot Y, Rodriguez-Vida A, Mamtani R, Yu EY, Nam K, Imai K, Homet Moreno B, Alva A; KEYNOTE-361 Investigators
Lancet Oncol 2021 Jul;22(7):931-945. Epub 2021 May 26 doi: 10.1016/S1470-2045(21)00152-2. PMID: 34051178
Sheng X, Yan X, Wang L, Shi Y, Yao X, Luo H, Shi B, Liu J, He Z, Yu G, Ying J, Han W, Hu C, Ling Y, Chi Z, Cui C, Si L, Fang J, Zhou A, Guo J
Clin Cancer Res 2021 Jan 1;27(1):43-51. Epub 2020 Oct 27 doi: 10.1158/1078-0432.CCR-20-2488. PMID: 33109737
Christensen E, Birkenkamp-Demtröder K, Sethi H, Shchegrova S, Salari R, Nordentoft I, Wu HT, Knudsen M, Lamy P, Lindskrog SV, Taber A, Balcioglu M, Vang S, Assaf Z, Sharma S, Tin AS, Srinivasan R, Hafez D, Reinert T, Navarro S, Olson A, Ram R, Dashner S, Rabinowitz M, Billings P, Sigurjonsson S, Andersen CL, Swenerton R, Aleshin A, Zimmermann B, Agerbæk M, Lin CJ, Jensen JB, Dyrskjøt L
J Clin Oncol 2019 Jun 20;37(18):1547-1557. Epub 2019 May 6 doi: 10.1200/JCO.18.02052. PMID: 31059311

Recent systematic reviews

Maisch P, Hwang EC, Kim K, Narayan VM, Bakker C, Kunath F, Dahm P
Cochrane Database Syst Rev 2023 Oct 9;10(10):CD013774. doi: 10.1002/14651858.CD013774.pub2. PMID: 37811690Free PMC Article
He W, Chen C, Lin T, Xu Q, Ye C, Du J, Huang J
Cancer Med 2023 Jul;12(14):15384-15403. Epub 2023 Jun 30 doi: 10.1002/cam4.6112. PMID: 37387501Free PMC Article
Zalay O, Yan M, Sigurdson S, Malone S, Vera-Badillo FE, Mahmud A
Curr Oncol 2022 Dec 20;30(1):19-36. doi: 10.3390/curroncol30010002. PMID: 36661651Free PMC Article
Chierigo F, Wenzel M, Würnschimmel C, Flammia RS, Horlemann B, Tian Z, Saad F, Chun FKH, Tilki D, Shariat SF, Gallucci M, Borghesi M, Suardi N, Terrone C, Karakiewicz PI
Crit Rev Oncol Hematol 2022 Jan;169:103534. Epub 2021 Nov 22 doi: 10.1016/j.critrevonc.2021.103534. PMID: 34823022
Shelley M, Cleves A, Wilt TJ, Mason M
Cochrane Database Syst Rev 2011 Apr 13;(4):CD008976. doi: 10.1002/14651858.CD008976.pub2. PMID: 21491413

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