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Metastatic Malignant Colorectal Neoplasm

MedGen UID:
1690980
•Concept ID:
C5206819
•
Neoplastic Process

Definition

A malignant neoplasm that arises in the colon or rectum that has spread from its original site of growth to other anatomic sites. [from NCI]

Professional guidelines

PubMed

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, Seligmann J, De Baere T, Osterlund P, Yoshino T, Martinelli E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2023 Jan;34(1):10-32. Epub 2022 Oct 25 doi: 10.1016/j.annonc.2022.10.003. PMID: 36307056
Clinical management of metastatic colorectal cancer in the era of precision medicine.
Ciardiello F, Ciardiello D, Martini G, Napolitano S, Tabernero J, Cervantes A
CA Cancer J Clin 2022 Jul;72(4):372-401. Epub 2022 Apr 26 doi: 10.3322/caac.21728. PMID: 35472088
Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review.
Biller LH, Schrag D
JAMA 2021 Feb 16;325(7):669-685. doi: 10.1001/jama.2021.0106. PMID: 33591350

Recent clinical studies

Etiology

Using Circulating Tumor DNA in Colorectal Cancer: Current and Evolving Practices.
Malla M, Loree JM, Kasi PM, Parikh AR
J Clin Oncol 2022 Aug 20;40(24):2846-2857. Epub 2022 Jul 15 doi: 10.1200/JCO.21.02615. PMID: 35839443Free PMC Article
Metastatic colorectal cancer and type 2 diabetes: prognostic and genetic interactions.
Ottaiano A, Circelli L, Santorsola M, Savarese G, Fontanella D, Gigantino V, Di Mauro A, Capuozzo M, Zappavigna S, Lombardi A, Perri F, Cascella M, Granata V, Capuozzo M, Nasti G, Caraglia M
Mol Oncol 2022 Jan;16(2):319-332. Epub 2021 Nov 19 doi: 10.1002/1878-0261.13122. PMID: 34668636Free PMC Article
Nivolumab for the treatment of colorectal cancer.
Smith KM, Desai J
Expert Rev Anticancer Ther 2018 Jul;18(7):611-618. Epub 2018 Jun 11 doi: 10.1080/14737140.2018.1480942. PMID: 29792730
Obesity and colorectal liver metastases: Mechanisms and management.
Pathak S, Pandanaboyana S, Daniels I, Smart N, Prasad KR
Surg Oncol 2016 Sep;25(3):246-51. Epub 2016 May 20 doi: 10.1016/j.suronc.2016.05.021. PMID: 27566030
Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Van Cutsem E, Cervantes A, Nordlinger B, Arnold D; ESMO Guidelines Working Group
Ann Oncol 2014 Sep;25 Suppl 3:iii1-9. Epub 2014 Sep 4 doi: 10.1093/annonc/mdu260. PMID: 25190710

Diagnosis

Using Circulating Tumor DNA in Colorectal Cancer: Current and Evolving Practices.
Malla M, Loree JM, Kasi PM, Parikh AR
J Clin Oncol 2022 Aug 20;40(24):2846-2857. Epub 2022 Jul 15 doi: 10.1200/JCO.21.02615. PMID: 35839443Free PMC Article
Cancers Metastatic to the Liver.
Rashidian N, Alseidi A, Kirks RC
Surg Clin North Am 2020 Jun;100(3):551-563. Epub 2020 Apr 3 doi: 10.1016/j.suc.2020.02.005. PMID: 32402300
Pulmonary enteric adenocarcinoma: an overview.
Palmirotta R, Lovero D, D'Oronzo S, Todisco A, Internò V, Mele F, Stucci LS, Silvestris F
Expert Rev Mol Med 2020 Apr 28;22:e1. doi: 10.1017/erm.2020.2. PMID: 32340641
Current and future targets and therapies in metastatic colorectal cancer.
Dzunic M, Petkovic I, Cvetanovic A, Vrbic S, Pejcic I
J BUON 2019 Sep-Oct;24(5):1785-1792. PMID: 31786838
Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Van Cutsem E, Cervantes A, Nordlinger B, Arnold D; ESMO Guidelines Working Group
Ann Oncol 2014 Sep;25 Suppl 3:iii1-9. Epub 2014 Sep 4 doi: 10.1093/annonc/mdu260. PMID: 25190710

Therapy

Organ-specific cholesterol metabolic aberration fuels liver metastasis of colorectal cancer.
Zhang KL, Zhu WW, Wang SH, Gao C, Pan JJ, Du ZG, Lu L, Jia HL, Dong QZ, Chen JH, Lu M, Qin LX
Theranostics 2021;11(13):6560-6572. Epub 2021 Apr 27 doi: 10.7150/thno.55609. PMID: 33995676Free PMC Article
Trifluridine/tipiracil plus bevacizumab for third-line management of metastatic colorectal cancer: SUNLIGHT study design.
Tabernero J, Taieb J, Prager GW, Ciardiello F, Fakih M, Leger C, Fougeray R, Amellal N, van Cutsem E
Future Oncol 2021 Jun;17(16):1977-1985. Epub 2021 Feb 11 doi: 10.2217/fon-2020-1238. PMID: 33569986
Chemotherapy Maintenance.
Kasi PM, Grothey A
Cancer J 2016 May-Jun;22(3):199-204. doi: 10.1097/PPO.0000000000000195. PMID: 27341599
Role of surgery in colorectal cancer liver metastases.
Akgül Ö, Çetinkaya E, Ersöz Ş, Tez M
World J Gastroenterol 2014 May 28;20(20):6113-22. doi: 10.3748/wjg.v20.i20.6113. PMID: 24876733Free PMC Article
Talaporfin sodium.
Wang S, Bromley E, Xu L, Chen JC, Keltner L
Expert Opin Pharmacother 2010 Jan;11(1):133-40. doi: 10.1517/14656560903463893. PMID: 20001435

Prognosis

Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406).
Kopetz S, Guthrie KA, Morris VK, Lenz HJ, Magliocco AM, Maru D, Yan Y, Lanman R, Manyam G, Hong DS, Sorokin A, Atreya CE, Diaz LA, Allegra C, Raghav KP, Wang SE, Lieu CH, McDonough SL, Philip PA, Hochster HS
J Clin Oncol 2021 Feb 1;39(4):285-294. Epub 2020 Dec 23 doi: 10.1200/JCO.20.01994. PMID: 33356422Free PMC Article
Prognosis of non-operative management of non-metastatic colorectal cancer in octa- and nonagenarians.
Franklyn J, Abdalkoddus M, Rossi B, Limnatitou D, Ahmed M, Sokker A, Douie WJ, Smolarek S
Ann R Coll Surg Engl 2020 Sep;102(7):504-509. Epub 2020 Aug 17 doi: 10.1308/rcsann.2020.0067. PMID: 32799666Free PMC Article
Cancers Metastatic to the Liver.
Rashidian N, Alseidi A, Kirks RC
Surg Clin North Am 2020 Jun;100(3):551-563. Epub 2020 Apr 3 doi: 10.1016/j.suc.2020.02.005. PMID: 32402300
Metastatic colorectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Van Cutsem E, Cervantes A, Nordlinger B, Arnold D; ESMO Guidelines Working Group
Ann Oncol 2014 Sep;25 Suppl 3:iii1-9. Epub 2014 Sep 4 doi: 10.1093/annonc/mdu260. PMID: 25190710
Colorectal cancer.
Brenner H, Kloor M, Pox CP
Lancet 2014 Apr 26;383(9927):1490-1502. Epub 2013 Nov 11 doi: 10.1016/S0140-6736(13)61649-9. PMID: 24225001

Clinical prediction guides

Disseminated epithelial cancers-An autopsy analysis.
Vaideeswar P, Patil S, Chaudhari J
Indian J Pathol Microbiol 2022 Jan-Mar;65(1):76-86. doi: 10.4103/IJPM.IJPM_1048_20. PMID: 35074969
Prognostic and predictive markers in liver limited stage IV colorectal cancer.
Rehman AH, Jones RP, Poston G
Eur J Surg Oncol 2019 Dec;45(12):2251-2256. Epub 2019 Jun 27 doi: 10.1016/j.ejso.2019.06.038. PMID: 31279594
Chemotherapy for colorectal cancer in the elderly.
Kim JH
World J Gastroenterol 2015 May 7;21(17):5158-66. doi: 10.3748/wjg.v21.i17.5158. PMID: 25954089Free PMC Article
Targeting BRAF mutant metastatic colorectal cancer: clinical implications and emerging therapeutic strategies.
Tie J, Desai J
Target Oncol 2015 Jun;10(2):179-88. Epub 2014 Aug 15 doi: 10.1007/s11523-014-0330-0. PMID: 25119972
Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases.
Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH
Ann Surg 1999 Sep;230(3):309-18; discussion 318-21. doi: 10.1097/00000658-199909000-00004. PMID: 10493478Free PMC Article

Recent systematic reviews

Treatment of Metastatic Colorectal Cancer: ASCO Guideline.
Morris VK, Kennedy EB, Baxter NN, Benson AB 3rd, Cercek A, Cho M, Ciombor KK, Cremolini C, Davis A, Deming DA, Fakih MG, Gholami S, Hong TS, Jaiyesimi I, Klute K, Lieu C, Sanoff H, Strickler JH, White S, Willis JA, Eng C
J Clin Oncol 2023 Jan 20;41(3):678-700. Epub 2022 Oct 17 doi: 10.1200/JCO.22.01690. PMID: 36252154Free PMC Article
Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis.
O'Sullivan DE, Sutherland RL, Town S, Chow K, Fan J, Forbes N, Heitman SJ, Hilsden RJ, Brenner DR
Clin Gastroenterol Hepatol 2022 Jun;20(6):1229-1240.e5. Epub 2021 Jan 29 doi: 10.1016/j.cgh.2021.01.037. PMID: 33524598
Performance of artificial intelligence in colonoscopy for adenoma and polyp detection: a systematic review and meta-analysis.
Hassan C, Spadaccini M, Iannone A, Maselli R, Jovani M, Chandrasekar VT, Antonelli G, Yu H, Areia M, Dinis-Ribeiro M, Bhandari P, Sharma P, Rex DK, Rösch T, Wallace M, Repici A
Gastrointest Endosc 2021 Jan;93(1):77-85.e6. Epub 2020 Jun 26 doi: 10.1016/j.gie.2020.06.059. PMID: 32598963
The Role of Maintenance Strategies in Metastatic Colorectal Cancer: A Systematic Review and Network Meta-analysis of Randomized Clinical Trials.
Sonbol MB, Mountjoy LJ, Firwana B, Liu AJ, Almader-Douglas D, Mody K, Hubbard J, Borad M, Ahn DH, Murad MH, Bekaii-Saab T
JAMA Oncol 2020 Mar 1;6(3):e194489. Epub 2020 Mar 12 doi: 10.1001/jamaoncol.2019.4489. PMID: 31855256Free PMC Article
Systematic review of blood diagnostic markers in colorectal cancer.
Nikolaou S, Qiu S, Fiorentino F, Rasheed S, Tekkis P, Kontovounisios C
Tech Coloproctol 2018 Jul;22(7):481-498. Epub 2018 Jul 18 doi: 10.1007/s10151-018-1820-3. PMID: 30022330Free PMC Article

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    Practice guidelines

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