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Prominent S wave in lead I

MedGen UID:
1691411
•Concept ID:
C5139188
•
Finding
HPO: HP:0032196

Definition

Increased amplitude (0.1 mV or more) and/or duration (40 ms or more) of the S wave as measured in lead I of the electrocardiogram. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProminent S wave in lead I

Recent clinical studies

Etiology

Acacetin suppresses the electrocardiographic and arrhythmic manifestations of the J wave syndromes.
Di Diego JM, Patocskai B, Barajas-Martinez H, Borbáth V, Ackerman MJ, Burashnikov A, Clatot J, Li GR, Robinson VM, Hu D, Antzelevitch C
PLoS One 2020;15(11):e0242747. Epub 2020 Nov 24 doi: 10.1371/journal.pone.0242747. PMID: 33232375Free PMC Article
Prediction of ventricular tachyarrhythmia in Brugada syndrome by right ventricular outflow tract conduction delay signs.
Ragab AAY, Houck CA, van der Does LJME, Lanters EAH, Muskens AJQM, de Groot NMS
J Cardiovasc Electrophysiol 2018 Jul;29(7):998-1003. Epub 2018 Apr 20 doi: 10.1111/jce.13496. PMID: 29608225
Prominent R wave in ECG lead V1 predicts improvement of left ventricular ejection fraction after cardiac resynchronization therapy in patients with or without left bundle branch block.
Bode WD, Bode MF, Gettes L, Jensen BC, Mounsey JP, Chung EH
Heart Rhythm 2015 Oct;12(10):2141-7. Epub 2015 Jun 3 doi: 10.1016/j.hrthm.2015.06.001. PMID: 26048194
Clinical significance of J-wave in elite athletes.
Pelliccia A, Quattrini FM
J Electrocardiol 2015 May-Jun;48(3):385-9. Epub 2015 Mar 12 doi: 10.1016/j.jelectrocard.2015.03.012. PMID: 25796101
Diagnosis of ST-elevation myocardial infarction in the presence of left bundle branch block with the ST-elevation to S-wave ratio in a modified Sgarbossa rule.
Smith SW, Dodd KW, Henry TD, Dvorak DM, Pearce LA
Ann Emerg Med 2012 Dec;60(6):766-76. Epub 2012 Aug 31 doi: 10.1016/j.annemergmed.2012.07.119. PMID: 22939607

Diagnosis

Diagnostic value of QRS and S wave variation in patients with suspicion of acute pulmonary embolism.
Çağdaş M, Karakoyun S, Rencüzoğulları İ, Karabağ Y, Artaç İ, İliş D, Hamideyin Ş, Karayol S, Çiftçi H, Çınar T
Am J Emerg Med 2018 Dec;36(12):2197-2202. Epub 2018 Mar 29 doi: 10.1016/j.ajem.2018.03.074. PMID: 29636293
Prediction of ventricular tachyarrhythmia in Brugada syndrome by right ventricular outflow tract conduction delay signs.
Ragab AAY, Houck CA, van der Does LJME, Lanters EAH, Muskens AJQM, de Groot NMS
J Cardiovasc Electrophysiol 2018 Jul;29(7):998-1003. Epub 2018 Apr 20 doi: 10.1111/jce.13496. PMID: 29608225
Prominent R wave in ECG lead V1 predicts improvement of left ventricular ejection fraction after cardiac resynchronization therapy in patients with or without left bundle branch block.
Bode WD, Bode MF, Gettes L, Jensen BC, Mounsey JP, Chung EH
Heart Rhythm 2015 Oct;12(10):2141-7. Epub 2015 Jun 3 doi: 10.1016/j.hrthm.2015.06.001. PMID: 26048194
Clinical significance of J-wave in elite athletes.
Pelliccia A, Quattrini FM
J Electrocardiol 2015 May-Jun;48(3):385-9. Epub 2015 Mar 12 doi: 10.1016/j.jelectrocard.2015.03.012. PMID: 25796101
Diagnosis of ST-elevation myocardial infarction in the presence of left bundle branch block with the ST-elevation to S-wave ratio in a modified Sgarbossa rule.
Smith SW, Dodd KW, Henry TD, Dvorak DM, Pearce LA
Ann Emerg Med 2012 Dec;60(6):766-76. Epub 2012 Aug 31 doi: 10.1016/j.annemergmed.2012.07.119. PMID: 22939607

Therapy

Prominent R wave in ECG lead V1 predicts improvement of left ventricular ejection fraction after cardiac resynchronization therapy in patients with or without left bundle branch block.
Bode WD, Bode MF, Gettes L, Jensen BC, Mounsey JP, Chung EH
Heart Rhythm 2015 Oct;12(10):2141-7. Epub 2015 Jun 3 doi: 10.1016/j.hrthm.2015.06.001. PMID: 26048194
Local increase of sleep slow wave activity after three weeks of working memory training in children and adolescents.
Pugin F, Metz AJ, Wolf M, Achermann P, Jenni OG, Huber R
Sleep 2015 Apr 1;38(4):607-14. doi: 10.5665/sleep.4580. PMID: 25669190Free PMC Article
Impact of methanol intoxication on the human electrocardiogram.
Jaff Z, McIntyre WF, Yazdan-Ashoori P, Baranchuk A
Cardiol J 2014;21(2):170-5. Epub 2013 May 15 doi: 10.5603/CJ.a2013.0053. PMID: 23677726
Sertindole causes distinct electrocardiographic T-wave morphology changes.
Nielsen J, Graff C, Hardahl T, Andersen MP, Kristoffersen J, Struijk JJ, Toft E, Meyer JM
Eur Neuropsychopharmacol 2009 Oct;19(10):702-7. Epub 2009 May 19 doi: 10.1016/j.euroneuro.2009.04.011. PMID: 19457646
Prominent ECG repolarization changes associated with intracoronary infusion of normal saline: comparisons with alternate coronary catheter flush solutions.
Romanelli MF, Meissner MD, Fromm BS, Spears JR
Catheter Cardiovasc Interv 1999 Dec;48(4):359-64. doi: 10.1002/(sici)1522-726x(199912)48:4<359::aid-ccd6>3.0.co;2-b. PMID: 10559813

Prognosis

Diagnostic value of QRS and S wave variation in patients with suspicion of acute pulmonary embolism.
Çağdaş M, Karakoyun S, Rencüzoğulları İ, Karabağ Y, Artaç İ, İliş D, Hamideyin Ş, Karayol S, Çiftçi H, Çınar T
Am J Emerg Med 2018 Dec;36(12):2197-2202. Epub 2018 Mar 29 doi: 10.1016/j.ajem.2018.03.074. PMID: 29636293
Mechanomyography-Based Wearable Monitor of Quasi-Isometric Muscle Fatigue for Motor Neural Prostheses.
Krueger E, Popović-Maneski L, Nohama P
Artif Organs 2018 Feb;42(2):208-218. Epub 2017 Aug 1 doi: 10.1111/aor.12973. PMID: 28762503
Prominent R wave in ECG lead V1 predicts improvement of left ventricular ejection fraction after cardiac resynchronization therapy in patients with or without left bundle branch block.
Bode WD, Bode MF, Gettes L, Jensen BC, Mounsey JP, Chung EH
Heart Rhythm 2015 Oct;12(10):2141-7. Epub 2015 Jun 3 doi: 10.1016/j.hrthm.2015.06.001. PMID: 26048194
Clinical significance of J-wave in elite athletes.
Pelliccia A, Quattrini FM
J Electrocardiol 2015 May-Jun;48(3):385-9. Epub 2015 Mar 12 doi: 10.1016/j.jelectrocard.2015.03.012. PMID: 25796101
Diagnosis of ST-elevation myocardial infarction in the presence of left bundle branch block with the ST-elevation to S-wave ratio in a modified Sgarbossa rule.
Smith SW, Dodd KW, Henry TD, Dvorak DM, Pearce LA
Ann Emerg Med 2012 Dec;60(6):766-76. Epub 2012 Aug 31 doi: 10.1016/j.annemergmed.2012.07.119. PMID: 22939607

Clinical prediction guides

Diagnostic value of QRS and S wave variation in patients with suspicion of acute pulmonary embolism.
Çağdaş M, Karakoyun S, Rencüzoğulları İ, Karabağ Y, Artaç İ, İliş D, Hamideyin Ş, Karayol S, Çiftçi H, Çınar T
Am J Emerg Med 2018 Dec;36(12):2197-2202. Epub 2018 Mar 29 doi: 10.1016/j.ajem.2018.03.074. PMID: 29636293
Prediction of ventricular tachyarrhythmia in Brugada syndrome by right ventricular outflow tract conduction delay signs.
Ragab AAY, Houck CA, van der Does LJME, Lanters EAH, Muskens AJQM, de Groot NMS
J Cardiovasc Electrophysiol 2018 Jul;29(7):998-1003. Epub 2018 Apr 20 doi: 10.1111/jce.13496. PMID: 29608225
Mechanomyography-Based Wearable Monitor of Quasi-Isometric Muscle Fatigue for Motor Neural Prostheses.
Krueger E, Popović-Maneski L, Nohama P
Artif Organs 2018 Feb;42(2):208-218. Epub 2017 Aug 1 doi: 10.1111/aor.12973. PMID: 28762503
Prominent R wave in ECG lead V1 predicts improvement of left ventricular ejection fraction after cardiac resynchronization therapy in patients with or without left bundle branch block.
Bode WD, Bode MF, Gettes L, Jensen BC, Mounsey JP, Chung EH
Heart Rhythm 2015 Oct;12(10):2141-7. Epub 2015 Jun 3 doi: 10.1016/j.hrthm.2015.06.001. PMID: 26048194
Diagnosis of ST-elevation myocardial infarction in the presence of left bundle branch block with the ST-elevation to S-wave ratio in a modified Sgarbossa rule.
Smith SW, Dodd KW, Henry TD, Dvorak DM, Pearce LA
Ann Emerg Med 2012 Dec;60(6):766-76. Epub 2012 Aug 31 doi: 10.1016/j.annemergmed.2012.07.119. PMID: 22939607

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