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Jejunal Neuroendocrine Tumor G2

MedGen UID:
1694173
•Concept ID:
C5205248
•
Neoplastic Process
Synonym: Jejunal NET G2

Definition

A well differentiated, intermediate grade neoplasm with neuroendocrine differentiation that arises from the jejunum. The mitotic count is 2-20 per 10 HPF and/or the Ki67 index is 3 to 20 percent. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJejunal Neuroendocrine Tumor G2

Recent clinical studies

Etiology

Sarcopenia in Patients with Advanced Gastrointestinal Well-Differentiated Neuroendocrine Tumors.
Romano E, Polici M, Marasco M, Lerose F, Dell'Unto E, Nardacci S, Zerunian M, Iannicelli E, Rinzivillo M, Laghi A, Annibale B, Panzuto F, Caruso D
Nutrients 2024 Jul 11;16(14) doi: 10.3390/nu16142224. PMID: 39064666Free PMC Article
Nationwide registry for patients with neuroendocrine neoplasm of pancreas, gastrointestinal tract, lungs, bronchi, or thymus in Japan.
Masui T, Ito T, Komoto I, Kojima S, Kasai Y, Tanabe M, Hara K, Hirano S, Okusaka T, Ichikawa Y, Kinugasa Y, Kokudo N, Kudo A, Sakurai A, Sugihara K, Date H, Haruma K, Hijioka S, Hirata K, Yamano H, Sakamine M, Kikuchi T, Fukushima M, Imamura M, Uemoto S
Int J Clin Oncol 2022 May;27(5):840-849. Epub 2022 Feb 18 doi: 10.1007/s10147-022-02130-y. PMID: 35178624Free PMC Article
Neuroendocrine neoplasms of the jejunum: a heterogeneous group with distinctive proximal and distal subsets.
Chopin-Laly X, Walter T, Hervieu V, Poncet G, Adham M, Guibal A, Chayvialle JA, Lombard-Bohas C, Scoazec JY
Virchows Arch 2013 May;462(5):489-99. Epub 2013 Apr 12 doi: 10.1007/s00428-013-1411-7. PMID: 23579432
Risk factors for disease progression in advanced jejunoileal neuroendocrine tumors.
Panzuto F, Campana D, Fazio N, Brizzi MP, Boninsegna L, Nori F, Di Meglio G, Capurso G, Scarpa A, Dogliotti L, De Braud F, Tomassetti P, Delle Fave G, Falconi M
Neuroendocrinology 2012;96(1):32-40. Epub 2011 Dec 28 doi: 10.1159/000334038. PMID: 22205326

Diagnosis

Sarcopenia in Patients with Advanced Gastrointestinal Well-Differentiated Neuroendocrine Tumors.
Romano E, Polici M, Marasco M, Lerose F, Dell'Unto E, Nardacci S, Zerunian M, Iannicelli E, Rinzivillo M, Laghi A, Annibale B, Panzuto F, Caruso D
Nutrients 2024 Jul 11;16(14) doi: 10.3390/nu16142224. PMID: 39064666Free PMC Article
Nationwide registry for patients with neuroendocrine neoplasm of pancreas, gastrointestinal tract, lungs, bronchi, or thymus in Japan.
Masui T, Ito T, Komoto I, Kojima S, Kasai Y, Tanabe M, Hara K, Hirano S, Okusaka T, Ichikawa Y, Kinugasa Y, Kokudo N, Kudo A, Sakurai A, Sugihara K, Date H, Haruma K, Hijioka S, Hirata K, Yamano H, Sakamine M, Kikuchi T, Fukushima M, Imamura M, Uemoto S
Int J Clin Oncol 2022 May;27(5):840-849. Epub 2022 Feb 18 doi: 10.1007/s10147-022-02130-y. PMID: 35178624Free PMC Article
Risk factors for disease progression in advanced jejunoileal neuroendocrine tumors.
Panzuto F, Campana D, Fazio N, Brizzi MP, Boninsegna L, Nori F, Di Meglio G, Capurso G, Scarpa A, Dogliotti L, De Braud F, Tomassetti P, Delle Fave G, Falconi M
Neuroendocrinology 2012;96(1):32-40. Epub 2011 Dec 28 doi: 10.1159/000334038. PMID: 22205326

Therapy

Risk factors for disease progression in advanced jejunoileal neuroendocrine tumors.
Panzuto F, Campana D, Fazio N, Brizzi MP, Boninsegna L, Nori F, Di Meglio G, Capurso G, Scarpa A, Dogliotti L, De Braud F, Tomassetti P, Delle Fave G, Falconi M
Neuroendocrinology 2012;96(1):32-40. Epub 2011 Dec 28 doi: 10.1159/000334038. PMID: 22205326

Prognosis

Nationwide registry for patients with neuroendocrine neoplasm of pancreas, gastrointestinal tract, lungs, bronchi, or thymus in Japan.
Masui T, Ito T, Komoto I, Kojima S, Kasai Y, Tanabe M, Hara K, Hirano S, Okusaka T, Ichikawa Y, Kinugasa Y, Kokudo N, Kudo A, Sakurai A, Sugihara K, Date H, Haruma K, Hijioka S, Hirata K, Yamano H, Sakamine M, Kikuchi T, Fukushima M, Imamura M, Uemoto S
Int J Clin Oncol 2022 May;27(5):840-849. Epub 2022 Feb 18 doi: 10.1007/s10147-022-02130-y. PMID: 35178624Free PMC Article
Neuroendocrine neoplasms of the jejunum: a heterogeneous group with distinctive proximal and distal subsets.
Chopin-Laly X, Walter T, Hervieu V, Poncet G, Adham M, Guibal A, Chayvialle JA, Lombard-Bohas C, Scoazec JY
Virchows Arch 2013 May;462(5):489-99. Epub 2013 Apr 12 doi: 10.1007/s00428-013-1411-7. PMID: 23579432
Risk factors for disease progression in advanced jejunoileal neuroendocrine tumors.
Panzuto F, Campana D, Fazio N, Brizzi MP, Boninsegna L, Nori F, Di Meglio G, Capurso G, Scarpa A, Dogliotti L, De Braud F, Tomassetti P, Delle Fave G, Falconi M
Neuroendocrinology 2012;96(1):32-40. Epub 2011 Dec 28 doi: 10.1159/000334038. PMID: 22205326

Clinical prediction guides

Risk factors for disease progression in advanced jejunoileal neuroendocrine tumors.
Panzuto F, Campana D, Fazio N, Brizzi MP, Boninsegna L, Nori F, Di Meglio G, Capurso G, Scarpa A, Dogliotti L, De Braud F, Tomassetti P, Delle Fave G, Falconi M
Neuroendocrinology 2012;96(1):32-40. Epub 2011 Dec 28 doi: 10.1159/000334038. PMID: 22205326

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