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Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type

MedGen UID:
1697485
Concept ID:
C5205065
Neoplastic Process

Definition

Diffuse large B-cell lymphoma germinal center B-cell type that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type

Professional guidelines

PubMed

Wilson WH, Hernandez-Ilizaliturri FJ, Dunleavy K, Little RF, O'Connor OA
Leuk Lymphoma 2010 Aug;51 Suppl 1(Suppl 1):1-10. doi: 10.3109/10428194.2010.500045. PMID: 20658952Free PMC Article

Recent clinical studies

Etiology

Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S, van Hoppe S, Burton C, Elshiekh M, Rule S, Crosbie N, Clear A, Calaminici M, Runge H, Hills RK, Scott DW, Rimsza LM, Menon G, Sha C, Davies JR, Nagano A, Davies A, Painter D, Smith A, Gribben J, Naresh KN, Westhead DR, Okosun J, Steele A, Hodson DJ, Balasubramanian S, Johnson P, Wang J, Fitzgibbon J
Blood Adv 2023 Mar 14;7(5):845-855. doi: 10.1182/bloodadvances.2022007536. PMID: 35947123Free PMC Article
Kinch A, Amini RM, Hollander P, Molin D, Sundström C, Enblad G
Acta Oncol 2020 Jun;59(6):673-680. Epub 2020 Feb 27 doi: 10.1080/0284186X.2020.1731924. PMID: 32102582
Yang JM, Jang JY, Jeon YK, Paik JH
J Transl Med 2018 Jun 11;16(1):162. doi: 10.1186/s12967-018-1537-0. PMID: 29890998Free PMC Article
Morin RD, Assouline S, Alcaide M, Mohajeri A, Johnston RL, Chong L, Grewal J, Yu S, Fornika D, Bushell K, Nielsen TH, Petrogiannis-Haliotis T, Crump M, Tosikyan A, Grande BM, MacDonald D, Rousseau C, Bayat M, Sesques P, Froment R, Albuquerque M, Monczak Y, Oros KK, Greenwood C, Riazalhosseini Y, Arseneault M, Camlioglu E, Constantin A, Pan-Hammarstrom Q, Peng R, Mann KK, Johnson NA
Clin Cancer Res 2016 May 1;22(9):2290-300. Epub 2015 Dec 8 doi: 10.1158/1078-0432.CCR-15-2123. PMID: 26647218
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716

Diagnosis

Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S, van Hoppe S, Burton C, Elshiekh M, Rule S, Crosbie N, Clear A, Calaminici M, Runge H, Hills RK, Scott DW, Rimsza LM, Menon G, Sha C, Davies JR, Nagano A, Davies A, Painter D, Smith A, Gribben J, Naresh KN, Westhead DR, Okosun J, Steele A, Hodson DJ, Balasubramanian S, Johnson P, Wang J, Fitzgibbon J
Blood Adv 2023 Mar 14;7(5):845-855. doi: 10.1182/bloodadvances.2022007536. PMID: 35947123Free PMC Article
Ofori K, Bhagat G, Rai AJ
Br J Clin Pharmacol 2021 Feb;87(2):284-294. Epub 2020 Nov 18 doi: 10.1111/bcp.14611. PMID: 33080045
Morin RD, Assouline S, Alcaide M, Mohajeri A, Johnston RL, Chong L, Grewal J, Yu S, Fornika D, Bushell K, Nielsen TH, Petrogiannis-Haliotis T, Crump M, Tosikyan A, Grande BM, MacDonald D, Rousseau C, Bayat M, Sesques P, Froment R, Albuquerque M, Monczak Y, Oros KK, Greenwood C, Riazalhosseini Y, Arseneault M, Camlioglu E, Constantin A, Pan-Hammarstrom Q, Peng R, Mann KK, Johnson NA
Clin Cancer Res 2016 May 1;22(9):2290-300. Epub 2015 Dec 8 doi: 10.1158/1078-0432.CCR-15-2123. PMID: 26647218
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716
Wilson WH, Hernandez-Ilizaliturri FJ, Dunleavy K, Little RF, O'Connor OA
Leuk Lymphoma 2010 Aug;51 Suppl 1(Suppl 1):1-10. doi: 10.3109/10428194.2010.500045. PMID: 20658952Free PMC Article

Therapy

Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S, van Hoppe S, Burton C, Elshiekh M, Rule S, Crosbie N, Clear A, Calaminici M, Runge H, Hills RK, Scott DW, Rimsza LM, Menon G, Sha C, Davies JR, Nagano A, Davies A, Painter D, Smith A, Gribben J, Naresh KN, Westhead DR, Okosun J, Steele A, Hodson DJ, Balasubramanian S, Johnson P, Wang J, Fitzgibbon J
Blood Adv 2023 Mar 14;7(5):845-855. doi: 10.1182/bloodadvances.2022007536. PMID: 35947123Free PMC Article
Kinch A, Amini RM, Hollander P, Molin D, Sundström C, Enblad G
Acta Oncol 2020 Jun;59(6):673-680. Epub 2020 Feb 27 doi: 10.1080/0284186X.2020.1731924. PMID: 32102582
Yang JM, Jang JY, Jeon YK, Paik JH
J Transl Med 2018 Jun 11;16(1):162. doi: 10.1186/s12967-018-1537-0. PMID: 29890998Free PMC Article
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716
Cabanillas F
Clin Lymphoma Myeloma Leuk 2011 Jun;11 Suppl 1:S87-90. Epub 2011 Apr 28 doi: 10.1016/j.clml.2011.03.029. PMID: 22035756

Prognosis

Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S, van Hoppe S, Burton C, Elshiekh M, Rule S, Crosbie N, Clear A, Calaminici M, Runge H, Hills RK, Scott DW, Rimsza LM, Menon G, Sha C, Davies JR, Nagano A, Davies A, Painter D, Smith A, Gribben J, Naresh KN, Westhead DR, Okosun J, Steele A, Hodson DJ, Balasubramanian S, Johnson P, Wang J, Fitzgibbon J
Blood Adv 2023 Mar 14;7(5):845-855. doi: 10.1182/bloodadvances.2022007536. PMID: 35947123Free PMC Article
Ofori K, Bhagat G, Rai AJ
Br J Clin Pharmacol 2021 Feb;87(2):284-294. Epub 2020 Nov 18 doi: 10.1111/bcp.14611. PMID: 33080045
Yang JM, Jang JY, Jeon YK, Paik JH
J Transl Med 2018 Jun 11;16(1):162. doi: 10.1186/s12967-018-1537-0. PMID: 29890998Free PMC Article
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716
Cabanillas F
Clin Lymphoma Myeloma Leuk 2011 Jun;11 Suppl 1:S87-90. Epub 2011 Apr 28 doi: 10.1016/j.clml.2011.03.029. PMID: 22035756

Clinical prediction guides

Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S, van Hoppe S, Burton C, Elshiekh M, Rule S, Crosbie N, Clear A, Calaminici M, Runge H, Hills RK, Scott DW, Rimsza LM, Menon G, Sha C, Davies JR, Nagano A, Davies A, Painter D, Smith A, Gribben J, Naresh KN, Westhead DR, Okosun J, Steele A, Hodson DJ, Balasubramanian S, Johnson P, Wang J, Fitzgibbon J
Blood Adv 2023 Mar 14;7(5):845-855. doi: 10.1182/bloodadvances.2022007536. PMID: 35947123Free PMC Article
Ofori K, Bhagat G, Rai AJ
Br J Clin Pharmacol 2021 Feb;87(2):284-294. Epub 2020 Nov 18 doi: 10.1111/bcp.14611. PMID: 33080045
Yang JM, Jang JY, Jeon YK, Paik JH
J Transl Med 2018 Jun 11;16(1):162. doi: 10.1186/s12967-018-1537-0. PMID: 29890998Free PMC Article
Morin RD, Assouline S, Alcaide M, Mohajeri A, Johnston RL, Chong L, Grewal J, Yu S, Fornika D, Bushell K, Nielsen TH, Petrogiannis-Haliotis T, Crump M, Tosikyan A, Grande BM, MacDonald D, Rousseau C, Bayat M, Sesques P, Froment R, Albuquerque M, Monczak Y, Oros KK, Greenwood C, Riazalhosseini Y, Arseneault M, Camlioglu E, Constantin A, Pan-Hammarstrom Q, Peng R, Mann KK, Johnson NA
Clin Cancer Res 2016 May 1;22(9):2290-300. Epub 2015 Dec 8 doi: 10.1158/1078-0432.CCR-15-2123. PMID: 26647218
Friedberg JW
Chin Clin Oncol 2015 Mar;4(1):9. doi: 10.3978/j.issn.2304-3865.2015.03.02. PMID: 25841716

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