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Decreased circulating A-type natriuretic peptide concentration

MedGen UID:
1699151
•Concept ID:
C5209267
•
Finding
Synonym: Decreased circulating A-type natriuretic peptide level
 
HPO: HP:0020184

Definition

A measurable reduction in circulating levels of Atrial natriuretic peptide hormone, a protein which plays an important role in the regulation of body fluid volume and blood pressure. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDecreased circulating A-type natriuretic peptide concentration

Professional guidelines

PubMed

The circulating renin-angiotensin system during treatment with metoprolol or captopril in patients with heart failure due to non-ischaemic dilated cardiomyopathy.
Jansson K, Dahlström U, Karlberg BE, Karlsson E, Nylander E, Nyquist O, Karlberg KE
J Intern Med 1999 May;245(5):435-43. doi: 10.1046/j.1365-2796.1999.00458.x. PMID: 10363743
Atrial natriuretic peptide and cyclic guanosine-3'5'-monophosphate in hypertensive pregnancy and during nifedipine treatment.
Manninen A, Vuorinen P, Laippala P, Tuimala R, Vapaatalo H
Pharmacol Toxicol 1994 Mar;74(3):153-7. doi: 10.1111/j.1600-0773.1994.tb01091.x. PMID: 8008721
Water-balance hormones during long-term follow-up of oral dDAVP treatment in diabetes insipidus.
Fjellestad-Paulsen A, Laborde K, Kindermans C, Czernichow P
Acta Paediatr 1993 Sep;82(9):752-7. doi: 10.1111/j.1651-2227.1993.tb12552.x. PMID: 8241672

Recent clinical studies

Etiology

Exercise-induced changes on exerkines that might influence brown adipose tissue metabolism in young sedentary adults.
Mendez-Gutierrez A, Aguilera CM, Osuna-Prieto FJ, Martinez-Tellez B, Rico Prados MC, Acosta FM, Llamas-Elvira JM, Ruiz JR, Sanchez-Delgado G
Eur J Sport Sci 2023 Apr;23(4):625-636. Epub 2022 Apr 25 doi: 10.1080/17461391.2022.2040597. PMID: 35152857
Sodium-Glucose Co-Transporter 2 Inhibitors and Insights from Biomarker Measurement in Heart Failure Patients.
Ibrahim NE, Januzzi JL
Clin Chem 2021 Jan 8;67(1):79-86. doi: 10.1093/clinchem/hvaa277. PMID: 33316036
Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites.
Pereira NL, Tosakulwong N, Scott CG, Jenkins GD, Prodduturi N, Chai Y, Olson TM, Rodeheffer RJ, Redfield MM, Weinshilboum RM, Burnett JC
Circ Cardiovasc Genet 2015 Feb;8(1):141-9. Epub 2014 Dec 1 doi: 10.1161/CIRCGENETICS.114.000624. PMID: 25452597Free PMC Article
Hormonal and renal effects of atrial natriuretic peptide in patients with secondary hypertension.
Hirata Y, Ishii M, Sugimoto T, Matsuoka H, Fukui K, Sugimoto T, Yamakado M, Tagawa H, Miyata A, Kangawa K
Circulation 1988 Dec;78(6):1401-10. doi: 10.1161/01.cir.78.6.1401. PMID: 2847885
ANP--a cardiac hormone and a putative central neurotransmitter.
Hedner T, Hedner J, Andersson O, Persson B, Pettersson A
Eur Heart J 1987 May;8 Suppl B:87-98. doi: 10.1093/eurheartj/8.suppl_b.87. PMID: 2956108

Diagnosis

Intensive Lifestyle Intervention Increases Plasma Midregional Proatrial Natriuretic Peptide Concentrations in Overweight Children.
Thomsen CF, Goharian TS, Larsen KT, Goetze JP, Andersen LB, Jeppesen JL
J Am Heart Assoc 2021 Jul 6;10(13):e020676. Epub 2021 Jun 28 doi: 10.1161/JAHA.121.020676. PMID: 34180245Free PMC Article
Sodium-Glucose Co-Transporter 2 Inhibitors and Insights from Biomarker Measurement in Heart Failure Patients.
Ibrahim NE, Januzzi JL
Clin Chem 2021 Jan 8;67(1):79-86. doi: 10.1093/clinchem/hvaa277. PMID: 33316036
The physiological and pathophysiological modulation of the endocrine function of the heart.
de Bold AJ, Ma KK, Zhang Y, de Bold ML, Bensimon M, Khoshbaten A
Can J Physiol Pharmacol 2001 Aug;79(8):705-14. PMID: 11558679
Circulating atrial natriuretic peptide plasma levels as a marker for cardiac damage after radiotherapy.
Wondergem J, Strootman EG, Frölich M, Leer JW, Noordijk EM
Radiother Oncol 2001 Mar;58(3):295-301. doi: 10.1016/s0167-8140(00)00303-0. PMID: 11230891
Plasma atrial natriuretic peptide: concentrations and circulating forms in normal man and patients with chronic renal failure.
Ogawa K, Smith AI, Hodsman GP, Jackson B, Woodcock EA, Johnston CI
Clin Exp Pharmacol Physiol 1987 Feb;14(2):95-102. doi: 10.1111/j.1440-1681.1987.tb00962.x. PMID: 2955981

Therapy

Intensive Lifestyle Intervention Increases Plasma Midregional Proatrial Natriuretic Peptide Concentrations in Overweight Children.
Thomsen CF, Goharian TS, Larsen KT, Goetze JP, Andersen LB, Jeppesen JL
J Am Heart Assoc 2021 Jul 6;10(13):e020676. Epub 2021 Jun 28 doi: 10.1161/JAHA.121.020676. PMID: 34180245Free PMC Article
Sodium-Glucose Co-Transporter 2 Inhibitors and Insights from Biomarker Measurement in Heart Failure Patients.
Ibrahim NE, Januzzi JL
Clin Chem 2021 Jan 8;67(1):79-86. doi: 10.1093/clinchem/hvaa277. PMID: 33316036
Acute effects of insulin on circulating natriuretic peptide levels in humans.
Bachmann KN, Deger SM, Alsouqi A, Huang S, Xu M, Ferguson JF, Su YR, Niswender KD, Ikizler TA, Wang TJ
PLoS One 2018;13(5):e0196869. Epub 2018 May 14 doi: 10.1371/journal.pone.0196869. PMID: 29758041Free PMC Article
Circulating atrial natriuretic peptide genetic association study identifies a novel gene cluster associated with stroke in whites.
Pereira NL, Tosakulwong N, Scott CG, Jenkins GD, Prodduturi N, Chai Y, Olson TM, Rodeheffer RJ, Redfield MM, Weinshilboum RM, Burnett JC
Circ Cardiovasc Genet 2015 Feb;8(1):141-9. Epub 2014 Dec 1 doi: 10.1161/CIRCGENETICS.114.000624. PMID: 25452597Free PMC Article
Hepatorenal syndrome: emerging perspectives of pathophysiology and therapy.
Epstein M
J Am Soc Nephrol 1994 Apr;4(10):1735-53. doi: 10.1681/ASN.V4101735. PMID: 8068872

Prognosis

Sodium-Glucose Co-Transporter 2 Inhibitors and Insights from Biomarker Measurement in Heart Failure Patients.
Ibrahim NE, Januzzi JL
Clin Chem 2021 Jan 8;67(1):79-86. doi: 10.1093/clinchem/hvaa277. PMID: 33316036
The physiological and pathophysiological modulation of the endocrine function of the heart.
de Bold AJ, Ma KK, Zhang Y, de Bold ML, Bensimon M, Khoshbaten A
Can J Physiol Pharmacol 2001 Aug;79(8):705-14. PMID: 11558679
Circulating atrial natriuretic peptide plasma levels as a marker for cardiac damage after radiotherapy.
Wondergem J, Strootman EG, Frölich M, Leer JW, Noordijk EM
Radiother Oncol 2001 Mar;58(3):295-301. doi: 10.1016/s0167-8140(00)00303-0. PMID: 11230891
Hepatorenal syndrome: emerging perspectives of pathophysiology and therapy.
Epstein M
J Am Soc Nephrol 1994 Apr;4(10):1735-53. doi: 10.1681/ASN.V4101735. PMID: 8068872
Atrial natriuretic peptide and cyclic guanosine-3'5'-monophosphate in hypertensive pregnancy and during nifedipine treatment.
Manninen A, Vuorinen P, Laippala P, Tuimala R, Vapaatalo H
Pharmacol Toxicol 1994 Mar;74(3):153-7. doi: 10.1111/j.1600-0773.1994.tb01091.x. PMID: 8008721

Clinical prediction guides

Sodium-Glucose Co-Transporter 2 Inhibitors and Insights from Biomarker Measurement in Heart Failure Patients.
Ibrahim NE, Januzzi JL
Clin Chem 2021 Jan 8;67(1):79-86. doi: 10.1093/clinchem/hvaa277. PMID: 33316036
Acute effects of insulin on circulating natriuretic peptide levels in humans.
Bachmann KN, Deger SM, Alsouqi A, Huang S, Xu M, Ferguson JF, Su YR, Niswender KD, Ikizler TA, Wang TJ
PLoS One 2018;13(5):e0196869. Epub 2018 May 14 doi: 10.1371/journal.pone.0196869. PMID: 29758041Free PMC Article
Dysregulation of pulsatility in aging IV. Pulsatile signaling and cardiovascular aging: functions and regulation of natriuretic peptide signaling.
Charloux A, Brandenberger G, Piquard F, Geny B
Ageing Res Rev 2008 Jul;7(3):151-63. Epub 2008 Feb 19 doi: 10.1016/j.arr.2007.12.001. PMID: 18243818
The physiological and pathophysiological modulation of the endocrine function of the heart.
de Bold AJ, Ma KK, Zhang Y, de Bold ML, Bensimon M, Khoshbaten A
Can J Physiol Pharmacol 2001 Aug;79(8):705-14. PMID: 11558679
Renal perfusion and metabolism in experimental endotoxin shock.
Gullichsen E
Acta Chir Scand Suppl 1991;560:7-31. PMID: 1828126

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