U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Penile Lymphoma

MedGen UID:
1699751
•Concept ID:
C5206640
•
Neoplastic Process
Synonyms: Lymphoma of the Penis; Primary Penile Lymphoma

Definition

A lymphoma that arises from penile skin, subcutis, corpora cavernosa, and spongiosum. Diffuse large B-cell lymphoma is the most common primary penile lymphoma. (WHO 2016) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPenile Lymphoma

Professional guidelines

PubMed

Clinical and anatomical guidelines in pelvic cancer contouring for radiotherapy treatment planning.
Portaluri M, Bambace S, Perez C, Giuliano G, Angone G, Scialpi M, Pili G, Didonna V, Alloro E
Cancer Radiother 2004 Aug;8(4):222-9. doi: 10.1016/j.canrad.2004.02.003. PMID: 15450515
The place of lymphangioadenography in the diagnosis and during the treatment of malignant diseases.
Vuksanovic M, Viamonte M Jr, Martin JE
Am J Roentgenol Radium Ther Nucl Med 1966 Jan;96(1):205-21. doi: 10.2214/ajr.96.1.205. PMID: 5900879

Recent clinical studies

Etiology

Advanced penile lymphoma: Case report and review of the literature.
Arambulo S, Calle A, Vela JM, Sotelo MJ
J Cancer Res Ther 2023 Apr-Jun;19(3):823-825. doi: 10.4103/jcrt.jcrt_593_21. PMID: 37470619
Penile cancer: a local case series and literature review.
Lau WD, Ong CH, Lim TP, Teo C
Singapore Med J 2015 Nov;56(11):637-40. doi: 10.11622/smedj.2015174. PMID: 26668410Free PMC Article
Primary penile lymphoma: the use of PET-CT for accurate staging and response monitoring.
Karunanithi S, Sharma P, Naswa N, Soundararajan R, Mohapatra T, Malhotra A, Bal C, Kumar R
Diagn Interv Radiol 2013 Mar-Apr;19(2):130-3. doi: 10.4261/1305-3825.DIR.6253-12.1. PMID: 23448700
Primary cutaneous CD30+ T-cell lymphoproliferative disorder presenting as paraphimosis: a case report and review of the literature.
McNab PM, Jukic DM, Mills O, Browarsky I
Dermatol Online J 2011 Jul 15;17(7):3. PMID: 21810388

Diagnosis

Advanced penile lymphoma: Case report and review of the literature.
Arambulo S, Calle A, Vela JM, Sotelo MJ
J Cancer Res Ther 2023 Apr-Jun;19(3):823-825. doi: 10.4103/jcrt.jcrt_593_21. PMID: 37470619
Penile cancer: a local case series and literature review.
Lau WD, Ong CH, Lim TP, Teo C
Singapore Med J 2015 Nov;56(11):637-40. doi: 10.11622/smedj.2015174. PMID: 26668410Free PMC Article
An isolated penile mass in a young adult turned out to be a primary marginal zone lymphoma of the penis. A case report and a review of literature.
Gentile G, Broccoli A, Brunocilla E, Schiavina R, Borghesi M, Romagnoli D, Bianchi L, Derenzini E, Agostinelli C, Franceschelli A, Colombo F, Zinzani PL
Anticancer Res 2013 Jun;33(6):2639-42. PMID: 23749921
Primary penile lymphoma: the use of PET-CT for accurate staging and response monitoring.
Karunanithi S, Sharma P, Naswa N, Soundararajan R, Mohapatra T, Malhotra A, Bal C, Kumar R
Diagn Interv Radiol 2013 Mar-Apr;19(2):130-3. doi: 10.4261/1305-3825.DIR.6253-12.1. PMID: 23448700
Primary penile lymphoma: diagnostic difficulties and management options.
Lin DW, Thorning DR, Krieger JN
Urology 1999 Aug;54(2):366. doi: 10.1016/s0090-4295(99)00114-4. PMID: 10754129

Therapy

Advanced penile lymphoma: Case report and review of the literature.
Arambulo S, Calle A, Vela JM, Sotelo MJ
J Cancer Res Ther 2023 Apr-Jun;19(3):823-825. doi: 10.4103/jcrt.jcrt_593_21. PMID: 37470619
An isolated penile mass in a young adult turned out to be a primary marginal zone lymphoma of the penis. A case report and a review of literature.
Gentile G, Broccoli A, Brunocilla E, Schiavina R, Borghesi M, Romagnoli D, Bianchi L, Derenzini E, Agostinelli C, Franceschelli A, Colombo F, Zinzani PL
Anticancer Res 2013 Jun;33(6):2639-42. PMID: 23749921
Primary penile diffuse large B cell lymphoma treated by local excision followed by rituximab-containing chemotherapy.
Kim HY, Oh SY, Lee S, Lee DM, Kim SH, Kwon HC, Hong SH, Yoon JH, Kim HJ
Acta Haematol 2008;120(3):150-2. Epub 2008 Nov 28 doi: 10.1159/000178146. PMID: 19039206
Primary B cell non-hodgkin lymphoma of the penis in a child.
Wei CC, Peng CT, Chiang IP, Wu KH
J Pediatr Hematol Oncol 2006 Jul;28(7):479-80. doi: 10.1097/01.mph.0000212951.50974.a9. PMID: 16825998
Primary penile lymphoma: the case for combined modality therapy.
el-Sharkawi A, Murphy J
Clin Oncol (R Coll Radiol) 1996;8(5):334-5. doi: 10.1016/s0936-6555(05)80726-5. PMID: 8934056

Prognosis

Primary penile lymphoma: the use of PET-CT for accurate staging and response monitoring.
Karunanithi S, Sharma P, Naswa N, Soundararajan R, Mohapatra T, Malhotra A, Bal C, Kumar R
Diagn Interv Radiol 2013 Mar-Apr;19(2):130-3. doi: 10.4261/1305-3825.DIR.6253-12.1. PMID: 23448700
Penile metastasis secondary to nasal NK/T-cell lymphoma.
Lan SK, Lin CW, Ho HC, Lee MS, Tzeng JE, Su YC
Urology 2008 Nov;72(5):1014-5. Epub 2008 Jul 17 doi: 10.1016/j.urology.2008.05.029. PMID: 18639328

Clinical prediction guides

Primary penile diffuse large B cell lymphoma treated by local excision followed by rituximab-containing chemotherapy.
Kim HY, Oh SY, Lee S, Lee DM, Kim SH, Kwon HC, Hong SH, Yoon JH, Kim HJ
Acta Haematol 2008;120(3):150-2. Epub 2008 Nov 28 doi: 10.1159/000178146. PMID: 19039206

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...