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Refractory Hepatocellular Carcinoma

MedGen UID:
1699770
Concept ID:
C5206563
Neoplastic Process

Definition

Hepatocellular carcinoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Hepatocellular Carcinoma

Professional guidelines

PubMed

Yang C, Guo L, Du J, Zhang Q, Zhang L
Biomolecules 2024 Feb 22;14(3) doi: 10.3390/biom14030265. PMID: 38540686Free PMC Article
An C, Fu Y, Li W, Zuo M, Wu P
Cancer 2023 Jul 15;129(14):2235-2244. Epub 2023 Apr 7 doi: 10.1002/cncr.34764. PMID: 37029486
Poggi G, Montagna B, Melchiorre F, Quaretti P, Delmonte A, Riccardi A, Tagliaferri B, Sottotetti F, Di Cesare P, Stella MG, Villani L, Zorzetto M, Greco G, Cornalba G, Bernardo G
Anticancer Res 2011 Nov;31(11):3927-33. PMID: 22110221

Recent clinical studies

Etiology

Tu X, Yang J, Zheng Y, Liang C, Tao Q, Tang X, Liu Z, Jiang L, He Z, Xie F, Zheng Y
Int Immunopharmacol 2022 Dec;113(Pt B):109401. Epub 2022 Nov 14 doi: 10.1016/j.intimp.2022.109401. PMID: 36395672
Cao Y, Ouyang T, Xiong F, Kan X, Chen L, Liang B, Zheng C
Hepatol Int 2021 Oct;15(5):1268-1277. Epub 2021 Aug 20 doi: 10.1007/s12072-021-10198-3. PMID: 34415515
Harding JJ, Do RK, Dika IE, Hollywood E, Uhlitskykh K, Valentino E, Wan P, Hamilton C, Feng X, Johnston A, Bomalaski J, Li CF, O'Reilly EM, Abou-Alfa GK
Cancer Chemother Pharmacol 2018 Sep;82(3):429-440. Epub 2018 Jul 3 doi: 10.1007/s00280-018-3635-3. PMID: 29971467Free PMC Article
Hiraoka A, Ishimaru Y, Kawasaki H, Aibiki T, Okudaira T, Toshimori A, Kawamura T, Yamago H, Nakahara H, Suga Y, Azemoto N, Miyata H, Miyamoto Y, Ninomiya T, Hirooka M, Abe M, Matsuura B, Hiasa Y, Michitaka K
Oncology 2015;89(3):167-74. Epub 2015 May 12 doi: 10.1159/000381808. PMID: 25999038
Yamanaka K, Hatano E, Kitamura K, Iida T, Ishii T, Machimito T, Taura K, Yasuchika K, Isoda H, Shibata T, Uemoto S
J Gastroenterol 2012 Mar;47(3):343-6. Epub 2011 Dec 21 doi: 10.1007/s00535-011-0511-x. PMID: 22183859

Diagnosis

Yang C, Guo L, Du J, Zhang Q, Zhang L
Biomolecules 2024 Feb 22;14(3) doi: 10.3390/biom14030265. PMID: 38540686Free PMC Article
Zhu H, Ma X, Zhao Y, Duo J
Medicine (Baltimore) 2018 Jun;97(25):e11214. doi: 10.1097/MD.0000000000011214. PMID: 29924049Free PMC Article
Hiraoka A, Ishimaru Y, Kawasaki H, Aibiki T, Okudaira T, Toshimori A, Kawamura T, Yamago H, Nakahara H, Suga Y, Azemoto N, Miyata H, Miyamoto Y, Ninomiya T, Hirooka M, Abe M, Matsuura B, Hiasa Y, Michitaka K
Oncology 2015;89(3):167-74. Epub 2015 May 12 doi: 10.1159/000381808. PMID: 25999038
Yamanaka K, Hatano E, Kitamura K, Iida T, Ishii T, Machimito T, Taura K, Yasuchika K, Isoda H, Shibata T, Uemoto S
J Gastroenterol 2012 Mar;47(3):343-6. Epub 2011 Dec 21 doi: 10.1007/s00535-011-0511-x. PMID: 22183859
Iwasa S, Ikeda M, Okusaka T, Ueno H, Morizane C, Nakachi K, Mitsunaga S, Kondo S, Hagihara A, Shimizu S, Satake M, Arai Y
Jpn J Clin Oncol 2011 Jun;41(6):770-5. Epub 2011 Apr 1 doi: 10.1093/jjco/hyr037. PMID: 21459893

Therapy

Yang C, Guo L, Du J, Zhang Q, Zhang L
Biomolecules 2024 Feb 22;14(3) doi: 10.3390/biom14030265. PMID: 38540686Free PMC Article
Cao Y, Ouyang T, Xiong F, Kan X, Chen L, Liang B, Zheng C
Hepatol Int 2021 Oct;15(5):1268-1277. Epub 2021 Aug 20 doi: 10.1007/s12072-021-10198-3. PMID: 34415515
Gabrielson A, Tesfaye AA, Marshall JL, Pishvaian MJ, Smaglo B, Jha R, Dorsch-Vogel K, Wang H, He AR
Cancer Chemother Pharmacol 2015 Nov;76(5):1073-9. Epub 2015 Oct 8 doi: 10.1007/s00280-015-2852-2. PMID: 26449224Free PMC Article
Yamanaka K, Hatano E, Kitamura K, Iida T, Ishii T, Machimito T, Taura K, Yasuchika K, Isoda H, Shibata T, Uemoto S
J Gastroenterol 2012 Mar;47(3):343-6. Epub 2011 Dec 21 doi: 10.1007/s00535-011-0511-x. PMID: 22183859
Poggi G, Montagna B, Melchiorre F, Quaretti P, Delmonte A, Riccardi A, Tagliaferri B, Sottotetti F, Di Cesare P, Stella MG, Villani L, Zorzetto M, Greco G, Cornalba G, Bernardo G
Anticancer Res 2011 Nov;31(11):3927-33. PMID: 22110221

Prognosis

Yang C, Guo L, Du J, Zhang Q, Zhang L
Biomolecules 2024 Feb 22;14(3) doi: 10.3390/biom14030265. PMID: 38540686Free PMC Article
Cao Y, Ouyang T, Xiong F, Kan X, Chen L, Liang B, Zheng C
Hepatol Int 2021 Oct;15(5):1268-1277. Epub 2021 Aug 20 doi: 10.1007/s12072-021-10198-3. PMID: 34415515
Hiraoka A, Ishimaru Y, Kawasaki H, Aibiki T, Okudaira T, Toshimori A, Kawamura T, Yamago H, Nakahara H, Suga Y, Azemoto N, Miyata H, Miyamoto Y, Ninomiya T, Hirooka M, Abe M, Matsuura B, Hiasa Y, Michitaka K
Oncology 2015;89(3):167-74. Epub 2015 May 12 doi: 10.1159/000381808. PMID: 25999038
Yamanaka K, Hatano E, Kitamura K, Iida T, Ishii T, Machimito T, Taura K, Yasuchika K, Isoda H, Shibata T, Uemoto S
J Gastroenterol 2012 Mar;47(3):343-6. Epub 2011 Dec 21 doi: 10.1007/s00535-011-0511-x. PMID: 22183859
Poggi G, Montagna B, Melchiorre F, Quaretti P, Delmonte A, Riccardi A, Tagliaferri B, Sottotetti F, Di Cesare P, Stella MG, Villani L, Zorzetto M, Greco G, Cornalba G, Bernardo G
Anticancer Res 2011 Nov;31(11):3927-33. PMID: 22110221

Clinical prediction guides

Yang C, Guo L, Du J, Zhang Q, Zhang L
Biomolecules 2024 Feb 22;14(3) doi: 10.3390/biom14030265. PMID: 38540686Free PMC Article
Harding JJ, Do RK, Dika IE, Hollywood E, Uhlitskykh K, Valentino E, Wan P, Hamilton C, Feng X, Johnston A, Bomalaski J, Li CF, O'Reilly EM, Abou-Alfa GK
Cancer Chemother Pharmacol 2018 Sep;82(3):429-440. Epub 2018 Jul 3 doi: 10.1007/s00280-018-3635-3. PMID: 29971467Free PMC Article
Hiraoka A, Ishimaru Y, Kawasaki H, Aibiki T, Okudaira T, Toshimori A, Kawamura T, Yamago H, Nakahara H, Suga Y, Azemoto N, Miyata H, Miyamoto Y, Ninomiya T, Hirooka M, Abe M, Matsuura B, Hiasa Y, Michitaka K
Oncology 2015;89(3):167-74. Epub 2015 May 12 doi: 10.1159/000381808. PMID: 25999038
Kishi Y, Saiura A, Yamamoto J, Koga R, Seki M, Morimura R, Yoshioka R, Kokudo N, Yamaguch T
Hepatogastroenterology 2012 Oct;59(119):2255-9. doi: 10.5754/hge10505. PMID: 23435140
Yamanaka K, Hatano E, Kitamura K, Iida T, Ishii T, Machimito T, Taura K, Yasuchika K, Isoda H, Shibata T, Uemoto S
J Gastroenterol 2012 Mar;47(3):343-6. Epub 2011 Dec 21 doi: 10.1007/s00535-011-0511-x. PMID: 22183859

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