Bouchentouf M, Forner K, Cuerquis J, Boulassel MR, Routy JP, Waller EK, Quyyumi AA, Paradis P, Schiffrin EL, Galipeau J
Cell Transplant 2011;20(9):1431-43. Epub 2011 Feb 3 doi: 10.3727/096368910X557164. PMID: 21294961

The significance of CD14+ monocytes in peripheral blood stem cells for the treatment of rat liver cirrhosis.

Wang J, Zhou X, Cui L, Yan L, Liang J, Cheng X, Qiao L, Shi Y, Han Z, Cao Y, Han Y, Fan D
Cytotherapy 2010 Dec;12(8):1022-34. Epub 2010 Sep 20 doi: 10.3109/14653249.2010.515578. PMID: 20849360

Effect of anti-TNFalpha treatment on circulating endothelial progenitor cells (EPCs) in rheumatoid arthritis.

Ablin JN, Boguslavski V, Aloush V, Elkayam O, Paran D, Caspi D, George J
Life Sci 2006 Nov 17;79(25):2364-9. Epub 2006 Aug 5 doi: 10.1016/j.lfs.2006.07.035. PMID: 16962143

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Recent clinical studies

Etiology

Reduced irisin levels in patients with acromegaly.

Sendur SN, Baykal G, Firlatan B, Aydin B, Lay I, Dagdelen S, Alikasifoglu M, Erbas T
Horm Mol Biol Clin Investig 2022 Sep 1;43(3):251-261. Epub 2022 Jul 19 doi: 10.1515/hmbci-2022-0009. PMID: 35851444

Albumin Infusion in Critically Ill COVID-19 Patients: Hemodilution and Anticoagulation.

Ramadori G
Int J Mol Sci 2021 Jul 1;22(13) doi: 10.3390/ijms22137126. PMID: 34281177 Free PMC Article

Exercise Intensity and Recovery on Circulating Brain-derived Neurotrophic Factor.

Reycraft JT, Islam H, Townsend LK, Hayward GC, Hazell TJ, Macpherson REK
Med Sci Sports Exerc 2020 May;52(5):1210-1217. doi: 10.1249/MSS.0000000000002242. PMID: 31815833

Circulating Fibronectin and Plasminogen Activator Inhibitor-2 Levels as Possible Predictors of Recurrent Placental Syndrome: An Exploratory Study.

Severens-Rijvers CAH, Al-Nasiry S, Ghossein-Doha C, Marzano S, Ten Cate H, Winkens B, Spaanderman MAE, Peeters LLH
Gynecol Obstet Invest 2017;82(4):355-360. Epub 2016 Sep 20 doi: 10.1159/000449385. PMID: 27644043 Free PMC Article

Association of serum irisin with metabolic syndrome in obese Chinese adults.

Yan B, Shi X, Zhang H, Pan L, Ma Z, Liu S, Liu Y, Li X, Yang S, Li Z
PLoS One 2014;9(4):e94235. Epub 2014 Apr 7 doi: 10.1371/journal.pone.0094235. PMID: 24709991 Free PMC Article

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Diagnosis

Changes of Circulating Irisin and High-Sensitivity C-Reactive Protein Levels in Morbidly Obese Individuals with Type 2 Diabetes After Roux-en-Y Gastric Bypass.

Shantavasinkul PC, Omotosho P, Corsino L, Muehlbauer MJ, Chattranukulchai P, Torquati A
J Laparoendosc Adv Surg Tech A 2022 Aug;32(8):817-822. Epub 2022 Feb 11 doi: 10.1089/lap.2021.0558. PMID: 35443789 Free PMC Article

Fibronectin regulates anoikis resistance via cell aggregate formation.

Han HJ, Sung JY, Kim SH, Yun UJ, Kim H, Jang EJ, Yoo HE, Hong EK, Goh SH, Moon A, Lee JS, Ye SK, Shim J, Kim YN
Cancer Lett 2021 Jun 28;508:59-72. Epub 2021 Mar 23 doi: 10.1016/j.canlet.2021.03.011. PMID: 33771684

Increased irisin versus reduced fibroblast growth factor1 (FGF1) in relation to adiposity, atherogenicity and hematological indices in metabolic syndrome patients with and without prediabetes.

Saber GY, Kasabri V, Saleh MI, Suyagh M, Halaseh L, Jaber R, Abu-Hassan H, Alalawi S
Horm Mol Biol Clin Investig 2019 Mar 6;38(1) doi: 10.1515/hmbci-2018-0063. PMID: 30840586

Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies.

Kurdiova T, Balaz M, Vician M, Maderova D, Vlcek M, Valkovic L, Srbecky M, Imrich R, Kyselovicova O, Belan V, Jelok I, Wolfrum C, Klimes I, Krssak M, Zemkova E, Gasperikova D, Ukropec J, Ukropcova B
J Physiol 2014 Mar 1;592(5):1091-107. Epub 2013 Dec 2 doi: 10.1113/jphysiol.2013.264655. PMID: 24297848 Free PMC Article

Uterine artery Doppler screening for adverse pregnancy outcome.

Papageorghiou AT, Roberts N
Curr Opin Obstet Gynecol 2005 Dec;17(6):584-90. doi: 10.1097/01.gco.0000191898.84567.04. PMID: 16258339

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Therapy

Circulating irisin in nonalcoholic fatty liver disease: an updated meta-analysis.

Qiu S, Wang Q, Cai X, Sun Z, Wu T
Endokrynol Pol 2023;74(1):47-54. Epub 2022 Sep 12 doi: 10.5603/EP.a2022.0067. PMID: 36094873

Changes of Circulating Irisin and High-Sensitivity C-Reactive Protein Levels in Morbidly Obese Individuals with Type 2 Diabetes After Roux-en-Y Gastric Bypass.

Albumin Infusion in Critically Ill COVID-19 Patients: Hemodilution and Anticoagulation.

Ramadori G
Int J Mol Sci 2021 Jul 1;22(13) doi: 10.3390/ijms22137126. PMID: 34281177 Free PMC Article

Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies.

Role of intracardiac renin-angiotensin-aldosterone system in extracellular matrix remodeling.

Lijnen PJ, Petrov VV
Methods Find Exp Clin Pharmacol 2003 Sep;25(7):541-64. doi: 10.1358/mf.2003.25.7.778094. PMID: 14571285

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Prognosis

Serum levels of irisin in postmenopausal women with osteoporotic hip fractures.

Liu K, Jing P, Liu Z, Wang Y, Han Z, Wang Y, Zheng Z, Wu Y, Wang T, Li Y, Zhang H, Wang L
Cytokine 2021 Dec;148:155708. Epub 2021 Sep 21 doi: 10.1016/j.cyto.2021.155708. PMID: 34560610

Albumin Infusion in Critically Ill COVID-19 Patients: Hemodilution and Anticoagulation.

Ramadori G
Int J Mol Sci 2021 Jul 1;22(13) doi: 10.3390/ijms22137126. PMID: 34281177 Free PMC Article

Increased irisin versus reduced fibroblast growth factor1 (FGF1) in relation to adiposity, atherogenicity and hematological indices in metabolic syndrome patients with and without prediabetes.

Saber GY, Kasabri V, Saleh MI, Suyagh M, Halaseh L, Jaber R, Abu-Hassan H, Alalawi S
Horm Mol Biol Clin Investig 2019 Mar 6;38(1) doi: 10.1515/hmbci-2018-0063. PMID: 30840586

Circulating Fibronectin and Plasminogen Activator Inhibitor-2 Levels as Possible Predictors of Recurrent Placental Syndrome: An Exploratory Study.

Association between irisin and major chronic diseases: a review.

Gouveia MC, Vella JP, Cafeo FR, Affonso Fonseca FL, Bacci MR
Eur Rev Med Pharmacol Sci 2016 Oct;20(19):4072-4077. PMID: 27775791

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Clinical prediction guides

Over-expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice.

Postic G, Solarz J, Loubière C, Kandiah J, Sawmynaden J, Adam F, Vilaire M, Léger T, Camadro JM, Victorino DB, Potier MC, Bun E, Moroy G, Kauskot A, Christophe O, Janel N
J Cell Mol Med 2023 Aug;27(15):2228-2238. Epub 2023 Jul 6 doi: 10.1111/jcmm.17817. PMID: 37415307 Free PMC Article

Circulating irisin in nonalcoholic fatty liver disease: an updated meta-analysis.

Qiu S, Wang Q, Cai X, Sun Z, Wu T
Endokrynol Pol 2023;74(1):47-54. Epub 2022 Sep 12 doi: 10.5603/EP.a2022.0067. PMID: 36094873

Circulating Fibronectin and Plasminogen Activator Inhibitor-2 Levels as Possible Predictors of Recurrent Placental Syndrome: An Exploratory Study.

Association between irisin and major chronic diseases: a review.

Gouveia MC, Vella JP, Cafeo FR, Affonso Fonseca FL, Bacci MR
Eur Rev Med Pharmacol Sci 2016 Oct;20(19):4072-4077. PMID: 27775791

Reduced number and activity of circulating endothelial progenitor cells from patients with hyperhomocysteinemia.

Zhu J, Wang X, Chen J, Sun J, Zhang F
Arch Med Res 2006 May;37(4):484-9. doi: 10.1016/j.arcmed.2005.09.017. PMID: 16624647

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