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Reduced circulating C-reactive protein concecntration

MedGen UID:
1704066
Concept ID:
C5139347
Finding
Synonym: Reduced C-reactive protein level
 
HPO: HP:0032437

Definition

An abnormal decrease of the C-reactive protein level in serum. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReduced circulating C-reactive protein concecntration

Conditions with this feature

Hyper-IgE recurrent infection syndrome 5, autosomal recessive
MedGen UID:
1716052
Concept ID:
C5394550
Disease or Syndrome
Hyper-IgE syndrome-5 with recurrent infections (HEIS5) is an autosomal recessive immunologic disorder characterized by onset of recurrent sinopulmonary and deep skin infections in early childhood. The infections are mostly caused by bacteria, including H. influenza and Staphylococcus aureus. Additional features include atopic dermatitis, impaired inflammatory responses during infection, increased serum IgE, and increased IL6 (147620) (summary by Spencer et al., 2019). For a discussion of genetic heterogeneity of hyper-IgE syndrome, see HIES1 (147060).

Professional guidelines

PubMed

Ryssdal M, Vanky E, Stokkeland LMT, Jarmund AH, Steinkjer B, Løvvik TS, Madssen TS, Iversen AC, Giskeødegård GF
J Clin Endocrinol Metab 2023 Aug 18;108(9):e743-e753. doi: 10.1210/clinem/dgad145. PMID: 36916886Free PMC Article
Berg DD, Ruff CT, Morrow DA
Clin Chem 2021 Jan 8;67(1):87-95. doi: 10.1093/clinchem/hvaa298. PMID: 33313695
Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC Jr, Sperling L, Virani SS, Yeboah J
Circulation 2019 Jun 18;139(25):e1082-e1143. Epub 2018 Nov 10 doi: 10.1161/CIR.0000000000000625. PMID: 30586774Free PMC Article

Recent clinical studies

Etiology

Rizo-Téllez SA, Sekheri M, Filep JG
Front Immunol 2023;14:1237729. Epub 2023 Jul 26 doi: 10.3389/fimmu.2023.1237729. PMID: 37564640Free PMC Article
Karlapudi V, Sunkara KB, Konda PR, Sarma KV, Rokkam MP
J Am Nutr Assoc 2023 Feb;42(2):159-168. Epub 2022 Feb 15 doi: 10.1080/07315724.2021.2014370. PMID: 35512759
Overgaard RV, Hertz CL, Ingwersen SH, Navarria A, Drucker DJ
Cell Rep Med 2021 Sep 21;2(9):100387. Epub 2021 Sep 3 doi: 10.1016/j.xcrm.2021.100387. PMID: 34622228Free PMC Article
Ghaedi E, Mohammadi M, Mohammadi H, Ramezani-Jolfaie N, Malekzadeh J, Hosseinzadeh M, Salehi-Abargouei A
Adv Nutr 2019 Jul 1;10(4):634-646. doi: 10.1093/advances/nmz007. PMID: 31041449Free PMC Article
Kim MJ, Hwang JH, Ko HJ, Na HB, Kim JH
Nutr Res 2015 May;35(5):409-20. Epub 2015 Apr 10 doi: 10.1016/j.nutres.2015.04.001. PMID: 25912765

Diagnosis

Rizo-Téllez SA, Sekheri M, Filep JG
Front Immunol 2023;14:1237729. Epub 2023 Jul 26 doi: 10.3389/fimmu.2023.1237729. PMID: 37564640Free PMC Article
Karlapudi V, Sunkara KB, Konda PR, Sarma KV, Rokkam MP
J Am Nutr Assoc 2023 Feb;42(2):159-168. Epub 2022 Feb 15 doi: 10.1080/07315724.2021.2014370. PMID: 35512759
Xiao L, Harrison DG
Can J Cardiol 2020 May;36(5):635-647. Epub 2020 Jan 24 doi: 10.1016/j.cjca.2020.01.013. PMID: 32389337Free PMC Article
Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC Jr, Sperling L, Virani SS, Yeboah J
Circulation 2019 Jun 18;139(25):e1082-e1143. Epub 2018 Nov 10 doi: 10.1161/CIR.0000000000000625. PMID: 30586774Free PMC Article
Libby P, Ridker PM, Maseri A
Circulation 2002 Mar 5;105(9):1135-43. doi: 10.1161/hc0902.104353. PMID: 11877368

Therapy

Prokopidis K, Mazidi M, Sankaranarayanan R, Tajik B, McArdle A, Isanejad M
Br J Nutr 2023 Mar 14;129(5):759-770. Epub 2022 Jun 16 doi: 10.1017/S0007114522001787. PMID: 35706399Free PMC Article
Karlapudi V, Sunkara KB, Konda PR, Sarma KV, Rokkam MP
J Am Nutr Assoc 2023 Feb;42(2):159-168. Epub 2022 Feb 15 doi: 10.1080/07315724.2021.2014370. PMID: 35512759
Larsson SC, Michaëlsson K, Mola-Caminal M, Höijer J, Mantzoros CS
Metabolism 2022 Dec;137:155329. Epub 2022 Oct 5 doi: 10.1016/j.metabol.2022.155329. PMID: 36208799
Overgaard RV, Hertz CL, Ingwersen SH, Navarria A, Drucker DJ
Cell Rep Med 2021 Sep 21;2(9):100387. Epub 2021 Sep 3 doi: 10.1016/j.xcrm.2021.100387. PMID: 34622228Free PMC Article
Kim MJ, Hwang JH, Ko HJ, Na HB, Kim JH
Nutr Res 2015 May;35(5):409-20. Epub 2015 Apr 10 doi: 10.1016/j.nutres.2015.04.001. PMID: 25912765

Prognosis

Rizo-Téllez SA, Sekheri M, Filep JG
Front Immunol 2023;14:1237729. Epub 2023 Jul 26 doi: 10.3389/fimmu.2023.1237729. PMID: 37564640Free PMC Article
Rasmussen LJH, Petersen JEV, Eugen-Olsen J
Front Immunol 2021;12:780641. Epub 2021 Dec 2 doi: 10.3389/fimmu.2021.780641. PMID: 34925360Free PMC Article
De Maeyer RPH, Chambers ES
Immunol Lett 2021 Feb;230:1-10. Epub 2020 Dec 10 doi: 10.1016/j.imlet.2020.12.003. PMID: 33309673
Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC Jr, Sperling L, Virani SS, Yeboah J
Circulation 2019 Jun 18;139(25):e1082-e1143. Epub 2018 Nov 10 doi: 10.1161/CIR.0000000000000625. PMID: 30586774Free PMC Article
Libby P, Ridker PM, Maseri A
Circulation 2002 Mar 5;105(9):1135-43. doi: 10.1161/hc0902.104353. PMID: 11877368

Clinical prediction guides

Rizo-Téllez SA, Sekheri M, Filep JG
Front Immunol 2023;14:1237729. Epub 2023 Jul 26 doi: 10.3389/fimmu.2023.1237729. PMID: 37564640Free PMC Article
Prokopidis K, Mazidi M, Sankaranarayanan R, Tajik B, McArdle A, Isanejad M
Br J Nutr 2023 Mar 14;129(5):759-770. Epub 2022 Jun 16 doi: 10.1017/S0007114522001787. PMID: 35706399Free PMC Article
De Maeyer RPH, Chambers ES
Immunol Lett 2021 Feb;230:1-10. Epub 2020 Dec 10 doi: 10.1016/j.imlet.2020.12.003. PMID: 33309673
Xiao L, Harrison DG
Can J Cardiol 2020 May;36(5):635-647. Epub 2020 Jan 24 doi: 10.1016/j.cjca.2020.01.013. PMID: 32389337Free PMC Article
Libby P, Ridker PM, Maseri A
Circulation 2002 Mar 5;105(9):1135-43. doi: 10.1161/hc0902.104353. PMID: 11877368

Recent systematic reviews

Byrne T, Cooke J, Bambrick P, McNeela E, Harrison M
Exp Gerontol 2023 Jun 15;177:112199. Epub 2023 May 8 doi: 10.1016/j.exger.2023.112199. PMID: 37156445
Prokopidis K, Mazidi M, Sankaranarayanan R, Tajik B, McArdle A, Isanejad M
Br J Nutr 2023 Mar 14;129(5):759-770. Epub 2022 Jun 16 doi: 10.1017/S0007114522001787. PMID: 35706399Free PMC Article
Brouillet S, Boursier G, Anav M, Du Boulet De La Boissière B, Gala A, Ferrieres-Hoa A, Touitou I, Hamamah S
Hum Reprod Update 2020 Sep 1;26(5):753-773. doi: 10.1093/humupd/dmaa012. PMID: 32469070
Ghaedi E, Mohammadi M, Mohammadi H, Ramezani-Jolfaie N, Malekzadeh J, Hosseinzadeh M, Salehi-Abargouei A
Adv Nutr 2019 Jul 1;10(4):634-646. doi: 10.1093/advances/nmz007. PMID: 31041449Free PMC Article
Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella-Tommasino J, Forman DE, Goldberg R, Heidenreich PA, Hlatky MA, Jones DW, Lloyd-Jones D, Lopez-Pajares N, Ndumele CE, Orringer CE, Peralta CA, Saseen JJ, Smith SC Jr, Sperling L, Virani SS, Yeboah J
Circulation 2019 Jun 18;139(25):e1082-e1143. Epub 2018 Nov 10 doi: 10.1161/CIR.0000000000000625. PMID: 30586774Free PMC Article

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