U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Primary Peritoneal Carcinosarcoma

MedGen UID:
1707301
•Concept ID:
C5206941
•
Neoplastic Process
Synonym: Primary Peritoneal Malignant Mixed Mesodermal (Mullerian) Tumor

Definition

An extremely rare and highly aggressive malignant neoplasm arising from the peritoneum. Morphologically, it is a high grade tumor, composed of carcinomatous and sarcomatous elements. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary Peritoneal Carcinosarcoma

Professional guidelines

PubMed

Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.
Armstrong DK, Alvarez RD, Bakkum-Gamez JN, Barroilhet L, Behbakht K, Berchuck A, Chen LM, Cristea M, DeRosa M, Eisenhauer EL, Gershenson DM, Gray HJ, Grisham R, Hakam A, Jain A, Karam A, Konecny GE, Leath CA, Liu J, Mahdi H, Martin L, Matei D, McHale M, McLean K, Miller DS, O'Malley DM, Percac-Lima S, Ratner E, Remmenga SW, Vargas R, Werner TL, Zsiros E, Burns JL, Engh AM
J Natl Compr Canc Netw 2021 Feb 2;19(2):191-226. doi: 10.6004/jnccn.2021.0007. PMID: 33545690
Primary treatment and prognostic factors of carcinosarcoma of the ovary, fallopian tube, and peritoneum: a Taiwanese Gynecologic Oncology Group Study.
Lu CH, Chen IH, Chen YJ, Wang KL, Qiu JT, Lin H, Lin WC, Liou WS, Huang YF, Lin YS, Tee YT, Hung YC
Int J Gynecol Cancer 2014 Mar;24(3):506-12. doi: 10.1097/IGC.0000000000000083. PMID: 24557435
Prognostic factors and treatment modalities in uterine sarcoma.
El Husseiny G, Al Bareedy N, Mourad WA, Mohamed G, Shoukri M, Subhi J, Ezzat A
Am J Clin Oncol 2002 Jun;25(3):256-60. doi: 10.1097/00000421-200206000-00010. PMID: 12040283

Recent clinical studies

Etiology

Comparison of first-line chemotherapy regimens for ovarian carcinosarcoma: a single institution case series and review of the literature.
Brackmann M, Stasenko M, Uppal S, Erba J, Reynolds RK, McLean K
BMC Cancer 2018 Feb 9;18(1):172. doi: 10.1186/s12885-018-4082-6. PMID: 29426293Free PMC Article

Diagnosis

Comparison of first-line chemotherapy regimens for ovarian carcinosarcoma: a single institution case series and review of the literature.
Brackmann M, Stasenko M, Uppal S, Erba J, Reynolds RK, McLean K
BMC Cancer 2018 Feb 9;18(1):172. doi: 10.1186/s12885-018-4082-6. PMID: 29426293Free PMC Article
Primary peritoneal carcinosarcoma.
Serrano Diana C, Gómez García MT, López Del Cerro E, Arones Collantes MA, García de la Torre JP, González Merlo G
J Obstet Gynaecol 2017 Apr;37(3):398-399. Epub 2016 Dec 28 doi: 10.1080/01443615.2016.1250732. PMID: 28029059
Primary peritoneal carcinosarcoma (malignant mixed mullerian tumor): Report of a case with five-year disease free survival after surgery and chemoradiation and a review of literature.
Ko ML, Jeng CJ, Huang SH, Shen J, Tzeng CR, Chen SC
Acta Oncol 2005;44(7):756-60. doi: 10.1080/02841860500252016. PMID: 16227168
Invasion of interstitial matrix by a novel cell line from primary peritoneal carcinosarcoma, and by established ovarian carcinoma cell lines: role of cell-matrix adhesion molecules, proteinases, and E-cadherin expression.
Kokenyesi R, Murray KP, Benshushan A, Huntley ED, Kao MS
Gynecol Oncol 2003 Apr;89(1):60-72. doi: 10.1016/s0090-8258(02)00152-x. PMID: 12694655

Therapy

Primary peritoneal carcinosarcoma: A report of two cases.
Fu HS, Wu YC, Chen CH, Liu WM, Cheng CJ, Chang CW, Wang ID, Chiu YH
Taiwan J Obstet Gynecol 2019 Mar;58(2):288-291. doi: 10.1016/j.tjog.2018.12.001. PMID: 30910155
Comparison of first-line chemotherapy regimens for ovarian carcinosarcoma: a single institution case series and review of the literature.
Brackmann M, Stasenko M, Uppal S, Erba J, Reynolds RK, McLean K
BMC Cancer 2018 Feb 9;18(1):172. doi: 10.1186/s12885-018-4082-6. PMID: 29426293Free PMC Article
Primary peritoneal carcinosarcoma (malignant mixed mullerian tumor): Report of a case with five-year disease free survival after surgery and chemoradiation and a review of literature.
Ko ML, Jeng CJ, Huang SH, Shen J, Tzeng CR, Chen SC
Acta Oncol 2005;44(7):756-60. doi: 10.1080/02841860500252016. PMID: 16227168

Prognosis

Primary peritoneal carcinosarcoma: A report of two cases.
Fu HS, Wu YC, Chen CH, Liu WM, Cheng CJ, Chang CW, Wang ID, Chiu YH
Taiwan J Obstet Gynecol 2019 Mar;58(2):288-291. doi: 10.1016/j.tjog.2018.12.001. PMID: 30910155
Primary peritoneal carcinosarcoma.
Serrano Diana C, Gómez García MT, López Del Cerro E, Arones Collantes MA, García de la Torre JP, González Merlo G
J Obstet Gynaecol 2017 Apr;37(3):398-399. Epub 2016 Dec 28 doi: 10.1080/01443615.2016.1250732. PMID: 28029059

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...