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Prostate Undifferentiated Pleomorphic Sarcoma

MedGen UID:
1707662
•Concept ID:
C5205729
•
Neoplastic Process

Definition

A rare undifferentiated pleomorphic sarcoma that arises from the prostate gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProstate Undifferentiated Pleomorphic Sarcoma

Professional guidelines

PubMed

Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group.
Trans-Atlantic RPS Working Group
Ann Surg Oncol 2016 Oct;23(11):3531-3540. Epub 2016 Aug 1 doi: 10.1245/s10434-016-5336-7. PMID: 27480354Free PMC Article
Refractory malignant fibrous histiocytoma: CT-guided treatment with a multidisciplinary, minimally invasive approach.
Shi F, Zhang F, Gao F, Wu K, Maharjan R, Li C
Technol Cancer Res Treat 2015 Feb;14(1):3-9. Epub 2014 Nov 11 doi: 10.7785/tcrt.2012.500390. PMID: 24325132
Retrovesical mass in men: pitfalls of differential diagnosis.
Dahms SE, Hohenfellner M, Linn JF, Eggersmann C, Haupt G, Thüroff JW
J Urol 1999 Apr;161(4):1244-8. doi: 10.1016/s0022-5347(01)61647-1. PMID: 10081878

Recent clinical studies

Etiology

Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group.
Trans-Atlantic RPS Working Group
Ann Surg Oncol 2016 Oct;23(11):3531-3540. Epub 2016 Aug 1 doi: 10.1245/s10434-016-5336-7. PMID: 27480354Free PMC Article
Long-term results with resection of radiation-induced soft tissue sarcomas.
Cha C, Antonescu CR, Quan ML, Maru S, Brennan MF
Ann Surg 2004 Jun;239(6):903-9; discussion 909-10. doi: 10.1097/01.sla.0000128686.51815.8b. PMID: 15166970Free PMC Article
Clinical significance of cytogenetic findings in solid tumors.
Mitelman F, Johansson B, Mandahl N, Mertens F
Cancer Genet Cytogenet 1997 May;95(1):1-8. doi: 10.1016/s0165-4608(96)00252-x. PMID: 9140447
Incidence and morphology of concurrent primary carcinomas of the urinary bladder and prostate in transurethral resection specimens.
Kunze E, Weidhase A, Schulz H
Zentralbl Pathol 1994 Jul;140(2):113-22. PMID: 7947617
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580

Diagnosis

Adult NTRK-rearranged spindle cell neoplasms of the viscera: with an emphasis on rare locations and heterologous elements.
Tsai JW, Lee JC, Hsieh TH, Huang SC, Lee PH, Liu TT, Kao YC, Chang CD, Weng TF, Li CF, Lin JC, Liang CW, Su YL, Chang IY, Wang YT, Chang NY, Yu SC, Wang JC, Huang HY
Mod Pathol 2022 Jul;35(7):911-921. Epub 2022 Feb 11 doi: 10.1038/s41379-021-01005-3. PMID: 35149769
Diagnosis of Prostate Cancer and Prostatitis Using near Infra-Red Fluorescent AgInSe/ZnS Quantum Dots.
Ncapayi V, Ninan N, Lebepe TC, Parani S, Girija AR, Bright R, Vasilev K, Maluleke R, Tsolekile N, Kodama T, Oluwafemi OS
Int J Mol Sci 2021 Nov 19;22(22) doi: 10.3390/ijms222212514. PMID: 34830396Free PMC Article
Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group.
Trans-Atlantic RPS Working Group
Ann Surg Oncol 2016 Oct;23(11):3531-3540. Epub 2016 Aug 1 doi: 10.1245/s10434-016-5336-7. PMID: 27480354Free PMC Article
Clinical significance of cytogenetic findings in solid tumors.
Mitelman F, Johansson B, Mandahl N, Mertens F
Cancer Genet Cytogenet 1997 May;95(1):1-8. doi: 10.1016/s0165-4608(96)00252-x. PMID: 9140447
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580

Therapy

Management of primary retroperitoneal sarcoma (RPS) in the adult: a consensus approach from the Trans-Atlantic RPS Working Group.
Trans-Atlantic RPS Working Group
Ann Surg Oncol 2015 Jan;22(1):256-63. Epub 2014 Oct 15 doi: 10.1245/s10434-014-3965-2. PMID: 25316486
Refractory malignant fibrous histiocytoma: CT-guided treatment with a multidisciplinary, minimally invasive approach.
Shi F, Zhang F, Gao F, Wu K, Maharjan R, Li C
Technol Cancer Res Treat 2015 Feb;14(1):3-9. Epub 2014 Nov 11 doi: 10.7785/tcrt.2012.500390. PMID: 24325132
Malignant fibrous histiocytoma after radiation therapy for prostate cancer: case report.
Miro AG, De Seta L, Lizza N, Kartheuser A, Detry R
J Chemother 1997 Apr;9(2):162. doi: 10.1179/joc.1997.9.2.162. PMID: 9176774

Prognosis

LHRH receptor expression in sarcomas of bone and soft tissue.
Deivaraju C, Temple HT, Block N, Robinson P, Schally AV
Horm Mol Biol Clin Investig 2016 Nov 1;28(2):105-111. doi: 10.1515/hmbci-2016-0001. PMID: 27639272
Pictorial review: Unusual tumours involving the prostate: radiological-pathological findings.
Chang JM, Lee HJ, Lee SE, Byun SS, Choe GY, Kim SH, Seong CK, Kim SH
Br J Radiol 2008 Nov;81(971):907-15. Epub 2008 Jul 28 doi: 10.1259/bjr/68294775. PMID: 18662962
Adult prostate sarcoma: the M. D. Anderson Cancer Center Experience.
Sexton WJ, Lance RE, Reyes AO, Pisters PW, Tu SM, Pisters LL
J Urol 2001 Aug;166(2):521-5. doi: 10.1016/s0022-5347(05)65974-5. PMID: 11458058
Clinical significance of cytogenetic findings in solid tumors.
Mitelman F, Johansson B, Mandahl N, Mertens F
Cancer Genet Cytogenet 1997 May;95(1):1-8. doi: 10.1016/s0165-4608(96)00252-x. PMID: 9140447
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580

Clinical prediction guides

Adult NTRK-rearranged spindle cell neoplasms of the viscera: with an emphasis on rare locations and heterologous elements.
Tsai JW, Lee JC, Hsieh TH, Huang SC, Lee PH, Liu TT, Kao YC, Chang CD, Weng TF, Li CF, Lin JC, Liang CW, Su YL, Chang IY, Wang YT, Chang NY, Yu SC, Wang JC, Huang HY
Mod Pathol 2022 Jul;35(7):911-921. Epub 2022 Feb 11 doi: 10.1038/s41379-021-01005-3. PMID: 35149769
Expression of PSMA in tumor neovasculature of high grade sarcomas including synovial sarcoma, rhabdomyosarcoma, undifferentiated sarcoma and MPNST.
Heitkötter B, Trautmann M, Grünewald I, Bögemann M, Rahbar K, Gevensleben H, Wardelmann E, Hartmann W, Steinestel K, Huss S
Oncotarget 2017 Jan 17;8(3):4268-4276. doi: 10.18632/oncotarget.13994. PMID: 28002805Free PMC Article
Adult prostate sarcoma: the M. D. Anderson Cancer Center Experience.
Sexton WJ, Lance RE, Reyes AO, Pisters PW, Tu SM, Pisters LL
J Urol 2001 Aug;166(2):521-5. doi: 10.1016/s0022-5347(05)65974-5. PMID: 11458058
Incidence and morphology of concurrent primary carcinomas of the urinary bladder and prostate in transurethral resection specimens.
Kunze E, Weidhase A, Schulz H
Zentralbl Pathol 1994 Jul;140(2):113-22. PMID: 7947617
Adult urological sarcoma.
Russo P, Brady MS, Conlon K, Hajdu SI, Fair WR, Herr HW, Brennan MF
J Urol 1992 Apr;147(4):1032-6; discussion 1036-7. doi: 10.1016/s0022-5347(17)37456-6. PMID: 1552580

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