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Solitary Cutaneous Reticulohistiocytosis

MedGen UID:
1708820
•Concept ID:
C5239292
•
Disease or Syndrome

Definition

A reactive cutaneous proliferation of macrophages associated with local trauma. It is characterized by the presence of giant cells with ground-glass cytoplasm. It presents as a single, asymptomatic, cutaneous or mucosal, firm xanthomatous to dark-red papule or nodule. (WHO 2018) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSolitary Cutaneous Reticulohistiocytosis

Recent clinical studies

Etiology

Multiple juvenile xanthogranuloma.
Garcia-Sirvent L, Espineira-Sicre J, Ruiz-Sanchez J, Cuesta-Montero L
Dermatol Online J 2024 Mar 15;30(1) doi: 10.5070/D330163291. PMID: 38762861
Dermoscopic follow-up of cutaneous rosai-dorfman: Spontaneous regression.
Hu C, Cao Y, Yang X, Cao Z, Xu M, Shi L, Wang X
Photodiagnosis Photodyn Ther 2021 Jun;34:102263. Epub 2021 Mar 23 doi: 10.1016/j.pdpdt.2021.102263. PMID: 33771755
Case for diagnosis. Solitary violaceous nodule on the toe.
Kieselova K, Santiago F, Amado C, Henrique M
An Bras Dermatol 2018 Jul-Aug;93(4):595-597. doi: 10.1590/abd1806-4841.20187445. PMID: 30066776Free PMC Article
Long-term follow-up of solitary intracerebral juvenile xanthogranuloma. Case report and review of the literature.
Fulkerson DH, Luerssen TG, Hattab EM, Kim DL, Smith JL
Pediatr Neurosurg 2008;44(6):480-5. Epub 2008 Dec 10 doi: 10.1159/000180303. PMID: 19066439
The non-Langerhans' cell histiocytoses in childhood.
Burgdorf WH, Zelger B
Cutis 1996 Sep;58(3):201-7. PMID: 8886534

Diagnosis

Multiple juvenile xanthogranuloma.
Garcia-Sirvent L, Espineira-Sicre J, Ruiz-Sanchez J, Cuesta-Montero L
Dermatol Online J 2024 Mar 15;30(1) doi: 10.5070/D330163291. PMID: 38762861
Dermoscopic follow-up of cutaneous rosai-dorfman: Spontaneous regression.
Hu C, Cao Y, Yang X, Cao Z, Xu M, Shi L, Wang X
Photodiagnosis Photodyn Ther 2021 Jun;34:102263. Epub 2021 Mar 23 doi: 10.1016/j.pdpdt.2021.102263. PMID: 33771755
Case for diagnosis. Solitary violaceous nodule on the toe.
Kieselova K, Santiago F, Amado C, Henrique M
An Bras Dermatol 2018 Jul-Aug;93(4):595-597. doi: 10.1590/abd1806-4841.20187445. PMID: 30066776Free PMC Article
Solitary juvenile xanthogranuloma with tibial involvement: a case report.
Zhi Y, Duan Y, Zhang H, Yin X, Qu T, Guan G, Su L, Dong Q
Int J Clin Exp Pathol 2015;8(1):164-70. Epub 2015 Jan 1 PMID: 25755703Free PMC Article
An infant who has dome-shaped papules.
Rana A, de Waal Malefyt S
Pediatr Rev 2012 Feb;33(2):86-8. doi: 10.1542/pir.33-2-86. PMID: 22301035

Therapy

Dermoscopic follow-up of cutaneous rosai-dorfman: Spontaneous regression.
Hu C, Cao Y, Yang X, Cao Z, Xu M, Shi L, Wang X
Photodiagnosis Photodyn Ther 2021 Jun;34:102263. Epub 2021 Mar 23 doi: 10.1016/j.pdpdt.2021.102263. PMID: 33771755
Primary cutaneous langerhans cell sarcoma: a report of four cases and review of the literature.
Sagransky MJ, Deng AC, Magro CM
Am J Dermatopathol 2013 Apr;35(2):196-204. doi: 10.1097/DAD.0b013e3182661c0b. PMID: 23051626
A 6-month old with total body flushing and a macular-papular lesion.
Conrad H, Gausche-Hill M, Burbulys D
Pediatr Emerg Care 2007 May;23(5):321-3. doi: 10.1097/01.pec.0000270165.85862.12. PMID: 17505276
Multiple eyelid defects in cutaneous Langerhans cell histiocytosis.
Wat CS, Yuen HK, Tse KK, Lam DS, Chan N
Ophthalmic Plast Reconstr Surg 2006 May-Jun;22(3):216-8. doi: 10.1097/01.iop.0000217567.90717.52. PMID: 16714935
Solitary orbital involvement with juvenile xanthogranuloma.
Shields CL, Shields JA, Buchanon HW
Arch Ophthalmol 1990 Nov;108(11):1587-9. doi: 10.1001/archopht.1990.01070130089037. PMID: 2123087

Prognosis

Dermoscopic follow-up of cutaneous rosai-dorfman: Spontaneous regression.
Hu C, Cao Y, Yang X, Cao Z, Xu M, Shi L, Wang X
Photodiagnosis Photodyn Ther 2021 Jun;34:102263. Epub 2021 Mar 23 doi: 10.1016/j.pdpdt.2021.102263. PMID: 33771755
Intracranial juvenile xanthogranuloma in an infant.
Myeong HS, Koh EJ, Cheon JE, Park SH, Kim SK
Childs Nerv Syst 2021 Oct;37(10):3265-3269. Epub 2021 Mar 4 doi: 10.1007/s00381-021-05088-w. PMID: 33660104
Primary cutaneous langerhans cell sarcoma: a report of four cases and review of the literature.
Sagransky MJ, Deng AC, Magro CM
Am J Dermatopathol 2013 Apr;35(2):196-204. doi: 10.1097/DAD.0b013e3182661c0b. PMID: 23051626
Cutaneous disseminated xanthogranuloma in an adult: case report and review of the literature.
Asarch A, Thiele JJ, Ashby-Richardson H, Norden PS
Cutis 2009 May;83(5):243-9. PMID: 19537282
Long-term follow-up of solitary intracerebral juvenile xanthogranuloma. Case report and review of the literature.
Fulkerson DH, Luerssen TG, Hattab EM, Kim DL, Smith JL
Pediatr Neurosurg 2008;44(6):480-5. Epub 2008 Dec 10 doi: 10.1159/000180303. PMID: 19066439

Clinical prediction guides

Dermoscopic follow-up of cutaneous rosai-dorfman: Spontaneous regression.
Hu C, Cao Y, Yang X, Cao Z, Xu M, Shi L, Wang X
Photodiagnosis Photodyn Ther 2021 Jun;34:102263. Epub 2021 Mar 23 doi: 10.1016/j.pdpdt.2021.102263. PMID: 33771755
Intracranial juvenile xanthogranuloma in an infant.
Myeong HS, Koh EJ, Cheon JE, Park SH, Kim SK
Childs Nerv Syst 2021 Oct;37(10):3265-3269. Epub 2021 Mar 4 doi: 10.1007/s00381-021-05088-w. PMID: 33660104
Solitary juvenile xanthogranuloma of the temporal muscle and bone penetrating the dura mater in a 2-month-old boy.
Cornips EM, Cox KE, Creytens DH, Granzen B, Weber JW, Ter Laak-Poort MP
J Neurosurg Pediatr 2009 Dec;4(6):588-91. doi: 10.3171/2009.7.PEDS09230. PMID: 19951050
Congenital solitary histiocytoma: a variant of Hashimoto-Pritzker histiocytosis. A retrospective study of 8 cases.
Zunino-Goutorbe C, Eschard C, Durlach A, Bernard P
Dermatology 2008;216(2):118-24. Epub 2008 Jan 23 doi: 10.1159/000111508. PMID: 18216473
Solitary orbital involvement with juvenile xanthogranuloma.
Shields CL, Shields JA, Buchanon HW
Arch Ophthalmol 1990 Nov;108(11):1587-9. doi: 10.1001/archopht.1990.01070130089037. PMID: 2123087

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