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Focal atonic seizure

MedGen UID:
1709168
•Concept ID:
C5397596
•
Disease or Syndrome
Synonyms: Focal onset atonic epileptic seizure; Focal onset atonic seizure; Focal-onset atonic epileptic seizure; Localised atonic seizure; Localised hypotonic seizure; Localized atonic seizure; Localized hypotonic seizure; Partial atonic seizure; Partial hypotonic seizure; Segmental atonic seizure; Segmental hypotonic seizure
SNOMED CT: Focal atonic seizure (1269366008); Focal-onset atonic epileptic seizure (1269366008); Focal onset atonic seizure (1269366008); Focal onset atonic epileptic seizure (1269366008)
 
HPO: HP:0020220

Definition

A focal seizure characterized at onset by sudden loss or diminution of muscle tone without apparent preceding myoclonic or tonic activity, typically lasting more than 500 ms but less than 2 seconds. It may involve the head, trunk, jaw or limb musculature. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal atonic seizure

Professional guidelines

PubMed

ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions.
Zuberi SM, Wirrell E, Yozawitz E, Wilmshurst JM, Specchio N, Riney K, Pressler R, Auvin S, Samia P, Hirsch E, Galicchio S, Triki C, Snead OC, Wiebe S, Cross JH, Tinuper P, Scheffer IE, Perucca E, Moshé SL, Nabbout R
Epilepsia 2022 Jun;63(6):1349-1397. Epub 2022 May 3 doi: 10.1111/epi.17239. PMID: 35503712
Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders.
Espay AJ, Aybek S, Carson A, Edwards MJ, Goldstein LH, Hallett M, LaFaver K, LaFrance WC Jr, Lang AE, Nicholson T, Nielsen G, Reuber M, Voon V, Stone J, Morgante F
JAMA Neurol 2018 Sep 1;75(9):1132-1141. doi: 10.1001/jamaneurol.2018.1264. PMID: 29868890Free PMC Article
Acute encephalitis - diagnosis and management.
Ellul M, Solomon T
Clin Med (Lond) 2018 Mar;18(2):155-159. doi: 10.7861/clinmedicine.18-2-155. PMID: 29626021Free PMC Article

Recent clinical studies

Diagnosis

Partial epilepsy presenting as focal atonic seizure: a case report.
Zhao J, Afra P, Adamolekun B
Seizure 2010 Jul;19(6):326-9. doi: 10.1016/j.seizure.2010.04.014. PMID: 20627778

Clinical prediction guides

Focal atonic seizures originated in the posterior temporoparietal area: A case report.
Nagino N, Kubota Y, Nakamoto H, Ito S, Oguni H
Clin Neurol Neurosurg 2021 Aug;207:106776. Epub 2021 Jun 24 doi: 10.1016/j.clineuro.2021.106776. PMID: 34192624

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