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Focal atonic seizure

MedGen UID:
Concept ID:
Disease or Syndrome
Synonyms: Focal onset atonic epileptic seizure; Focal onset atonic seizure; Focal-onset atonic epileptic seizure; Localised atonic seizure; Localised hypotonic seizure; Localized atonic seizure; Localized hypotonic seizure; Partial atonic seizure; Partial hypotonic seizure; Segmental atonic seizure; Segmental hypotonic seizure
SNOMED CT: Focal atonic seizure (1269366008); Focal-onset atonic epileptic seizure (1269366008); Focal onset atonic seizure (1269366008); Focal onset atonic epileptic seizure (1269366008)
HPO: HP:0020220


A focal seizure characterized at onset by sudden loss or diminution of muscle tone without apparent preceding myoclonic or tonic activity, typically lasting more than 500 ms but less than 2 seconds. It may involve the head, trunk, jaw or limb musculature. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal atonic seizure

Professional guidelines


Zuberi SM, Wirrell E, Yozawitz E, Wilmshurst JM, Specchio N, Riney K, Pressler R, Auvin S, Samia P, Hirsch E, Galicchio S, Triki C, Snead OC, Wiebe S, Cross JH, Tinuper P, Scheffer IE, Perucca E, Moshé SL, Nabbout R
Epilepsia 2022 Jun;63(6):1349-1397. Epub 2022 May 3 doi: 10.1111/epi.17239. PMID: 35503712
Espay AJ, Aybek S, Carson A, Edwards MJ, Goldstein LH, Hallett M, LaFaver K, LaFrance WC Jr, Lang AE, Nicholson T, Nielsen G, Reuber M, Voon V, Stone J, Morgante F
JAMA Neurol 2018 Sep 1;75(9):1132-1141. doi: 10.1001/jamaneurol.2018.1264. PMID: 29868890Free PMC Article
Ellul M, Solomon T
Clin Med (Lond) 2018 Mar;18(2):155-159. doi: 10.7861/clinmedicine.18-2-155. PMID: 29626021Free PMC Article

Recent clinical studies


Zhao J, Afra P, Adamolekun B
Seizure 2010 Jul;19(6):326-9. doi: 10.1016/j.seizure.2010.04.014. PMID: 20627778

Clinical prediction guides

Nagino N, Kubota Y, Nakamoto H, Ito S, Oguni H
Clin Neurol Neurosurg 2021 Aug;207:106776. Epub 2021 Jun 24 doi: 10.1016/j.clineuro.2021.106776. PMID: 34192624

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