U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal renal tubular lumen morphology

MedGen UID:
1709586
•Concept ID:
C5397950
•
Anatomical Abnormality
Synonym: Abnormal renal tubular luminal morphology
 
HPO: HP:0032950

Definition

Abnormal structure or form of the lumen (opening) of kidney tubules. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal renal tubular lumen morphology

Recent clinical studies

Etiology

A cross-sectional study on the relationship between hematological data and quantitative morphological indices from kidney biopsies in different glomerular diseases.
Nigro M, Viggiano D, Ragone V, Trabace T, di Palma A, Rossini M, Capasso G, Gesualdo L, Gigliotti G
BMC Nephrol 2018 Mar 14;19(1):62. doi: 10.1186/s12882-018-0846-0. PMID: 29540159Free PMC Article
Evidence for a role of uromodulin in chronic kidney disease progression.
Prajczer S, Heidenreich U, Pfaller W, Kotanko P, Lhotta K, Jennings P
Nephrol Dial Transplant 2010 Jun;25(6):1896-903. Epub 2010 Jan 14 doi: 10.1093/ndt/gfp748. PMID: 20075439

Diagnosis

Disruption of the glomerular basement membrane associated with nutcracker syndrome and double inferior vena cava in Noonan syndrome: a case report.
Omori A, Katayama K, Saiki R, Masui S, Suzuki K, Kanii Y, Tsujimoto K, Nakamori S, Kurita T, Murata T, Inoue T, Dohi K
BMC Nephrol 2022 Feb 12;23(1):65. doi: 10.1186/s12882-022-02671-4. PMID: 35151252Free PMC Article
Pannexin-1 mediates fluid shear stress-sensitive purinergic signaling and cyst growth in polycystic kidney disease.
Verschuren EHJ, Rigalli JP, Castenmiller C, Rohrbach MU, Bindels RJM, Peters DJM, Arjona FJ, Hoenderop JGJ
FASEB J 2020 May;34(5):6382-6398. Epub 2020 Mar 11 doi: 10.1096/fj.201902901R. PMID: 32159259
Acute kidney injury due to thin basement membrane disease mimicking Deferasirox nephrotoxicity: a case report.
Oda K, Katayama K, Tanoue A, Murata T, Hirota Y, Mizoguchi S, Hirabayashi Y, Ito T, Ishikawa E, Dohi K, Ito M
BMC Nephrol 2018 Dec 17;19(1):363. doi: 10.1186/s12882-018-1180-2. PMID: 30558557Free PMC Article
A cross-sectional study on the relationship between hematological data and quantitative morphological indices from kidney biopsies in different glomerular diseases.
Nigro M, Viggiano D, Ragone V, Trabace T, di Palma A, Rossini M, Capasso G, Gesualdo L, Gigliotti G
BMC Nephrol 2018 Mar 14;19(1):62. doi: 10.1186/s12882-018-0846-0. PMID: 29540159Free PMC Article
Autosomal dominant polycystic kidney disease: recent advances in pathogenesis and potential therapies.
Mochizuki T, Tsuchiya K, Nitta K
Clin Exp Nephrol 2013 Jun;17(3):317-26. Epub 2012 Nov 29 doi: 10.1007/s10157-012-0741-0. PMID: 23192769

Therapy

Acute kidney injury due to thin basement membrane disease mimicking Deferasirox nephrotoxicity: a case report.
Oda K, Katayama K, Tanoue A, Murata T, Hirota Y, Mizoguchi S, Hirabayashi Y, Ito T, Ishikawa E, Dohi K, Ito M
BMC Nephrol 2018 Dec 17;19(1):363. doi: 10.1186/s12882-018-1180-2. PMID: 30558557Free PMC Article
Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice.
Morigi M, Introna M, Imberti B, Corna D, Abbate M, Rota C, Rottoli D, Benigni A, Perico N, Zoja C, Rambaldi A, Remuzzi A, Remuzzi G
Stem Cells 2008 Aug;26(8):2075-82. Epub 2008 May 22 doi: 10.1634/stemcells.2007-0795. PMID: 18499895
Multicystic transformation of kidneys in chronic renal failure.
Mickisch O, Bommer J, Bachmann S, Waldherr R, Mann JF, Ritz E
Nephron 1984;38(2):93-9. doi: 10.1159/000183288. PMID: 6382039

Prognosis

Clinicopathological significance of intratubular giant macrophages in progressive glomerulonephritis.
Oda T, Hotta O, Taguma Y, Kitamura H, Sugai H, Onodera S, Horigome I, Suzuki K, Shouji Y, Furuta T, Chiba S, Yoshizawa N, Nagura H
Kidney Int 1998 May;53(5):1190-200. doi: 10.1046/j.1523-1755.1998.00886.x. PMID: 9573533

Clinical prediction guides

Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China.
Su H, Yang M, Wan C, Yi LX, Tang F, Zhu HY, Yi F, Yang HC, Fogo AB, Nie X, Zhang C
Kidney Int 2020 Jul;98(1):219-227. Epub 2020 Apr 9 doi: 10.1016/j.kint.2020.04.003. PMID: 32327202Free PMC Article
Pannexin-1 mediates fluid shear stress-sensitive purinergic signaling and cyst growth in polycystic kidney disease.
Verschuren EHJ, Rigalli JP, Castenmiller C, Rohrbach MU, Bindels RJM, Peters DJM, Arjona FJ, Hoenderop JGJ
FASEB J 2020 May;34(5):6382-6398. Epub 2020 Mar 11 doi: 10.1096/fj.201902901R. PMID: 32159259
A cross-sectional study on the relationship between hematological data and quantitative morphological indices from kidney biopsies in different glomerular diseases.
Nigro M, Viggiano D, Ragone V, Trabace T, di Palma A, Rossini M, Capasso G, Gesualdo L, Gigliotti G
BMC Nephrol 2018 Mar 14;19(1):62. doi: 10.1186/s12882-018-0846-0. PMID: 29540159Free PMC Article
Evidence for a role of uromodulin in chronic kidney disease progression.
Prajczer S, Heidenreich U, Pfaller W, Kotanko P, Lhotta K, Jennings P
Nephrol Dial Transplant 2010 Jun;25(6):1896-903. Epub 2010 Jan 14 doi: 10.1093/ndt/gfp748. PMID: 20075439
Clinicopathological significance of intratubular giant macrophages in progressive glomerulonephritis.
Oda T, Hotta O, Taguma Y, Kitamura H, Sugai H, Onodera S, Horigome I, Suzuki K, Shouji Y, Furuta T, Chiba S, Yoshizawa N, Nagura H
Kidney Int 1998 May;53(5):1190-200. doi: 10.1046/j.1523-1755.1998.00886.x. PMID: 9573533

Supplemental Content

Table of contents

    Clinical resources

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...