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Retroperitoneal Pain Syndrome

MedGen UID:
1709950
•Concept ID:
C5237338
•
Disease or Syndrome

Definition

A pain syndrome characterized by epigastric and mid-back pain, typically experienced as a dull or aching pain. Frequent causes include pancreatic cancer and retroperitoneal lymphadenopathy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRetroperitoneal Pain Syndrome

Professional guidelines

PubMed

Retroperitoneal Causes of Genitourinary Pain Syndromes: Systematic Approach to Evaluation and Management.
Khalife T, Hagen AM, Alm JEC
Sex Med Rev 2022 Oct 1;10(4):529-542. doi: 10.1016/j.sxmr.2022.06.009. PMID: 37051972
Retroperitoneal Causes of Genitourinary Pain Syndromes: Systematic Approach to Evaluation and Management.
Khalife T, Hagen AM, Alm JEC
Sex Med Rev 2022 Oct;10(4):529-542. Epub 2022 Sep 8 doi: 10.1016/j.sxmr.2022.06.009. PMID: 36088274
American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis.
Baron TH, DiMaio CJ, Wang AY, Morgan KA
Gastroenterology 2020 Jan;158(1):67-75.e1. Epub 2019 Aug 31 doi: 10.1053/j.gastro.2019.07.064. PMID: 31479658

Recent clinical studies

Etiology

Endovascular management of nutcracker syndrome in an adolescent patient population.
Cronan JC, Hawkins CM, Kennedy SS, Marshall KW, Rostad BS, Gill AE
Pediatr Radiol 2021 Jul;51(8):1487-1496. Epub 2021 Mar 11 doi: 10.1007/s00247-021-04986-0. PMID: 33704542
Epidural corticosteroid injections for lumbosacral radicular pain.
Oliveira CB, Maher CG, Ferreira ML, Hancock MJ, Oliveira VC, McLachlan AJ, Koes BW, Ferreira PH, Cohen SP, Pinto RZ
Cochrane Database Syst Rev 2020 Apr 9;4(4):CD013577. doi: 10.1002/14651858.CD013577. PMID: 32271952Free PMC Article
Median arcuate ligament syndrome.
Goodall R, Langridge B, Onida S, Ellis M, Lane T, Davies AH
J Vasc Surg 2020 Jun;71(6):2170-2176. Epub 2019 Dec 25 doi: 10.1016/j.jvs.2019.11.012. PMID: 31882314
American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis.
Baron TH, DiMaio CJ, Wang AY, Morgan KA
Gastroenterology 2020 Jan;158(1):67-75.e1. Epub 2019 Aug 31 doi: 10.1053/j.gastro.2019.07.064. PMID: 31479658
Surgical Management and Prevention of Ovarian Remnant.
Wasson MN, Magrina J
J Minim Invasive Gynecol 2019 Jul-Aug;26(5):811. Epub 2018 Nov 8 doi: 10.1016/j.jmig.2018.10.021. PMID: 30414999

Diagnosis

Thoracic manifestations of IgG4-related disease.
Muller R, Ebbo M, Habert P, Daniel L, Briantais A, Chanez P, Gaubert JY, Schleinitz N
Respirology 2023 Feb;28(2):120-131. Epub 2022 Nov 27 doi: 10.1111/resp.14422. PMID: 36437514Free PMC Article
Epidural corticosteroid injections for lumbosacral radicular pain.
Oliveira CB, Maher CG, Ferreira ML, Hancock MJ, Oliveira VC, McLachlan AJ, Koes BW, Ferreira PH, Cohen SP, Pinto RZ
Cochrane Database Syst Rev 2020 Apr 9;4(4):CD013577. doi: 10.1002/14651858.CD013577. PMID: 32271952Free PMC Article
Median arcuate ligament syndrome.
Goodall R, Langridge B, Onida S, Ellis M, Lane T, Davies AH
J Vasc Surg 2020 Jun;71(6):2170-2176. Epub 2019 Dec 25 doi: 10.1016/j.jvs.2019.11.012. PMID: 31882314
American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis.
Baron TH, DiMaio CJ, Wang AY, Morgan KA
Gastroenterology 2020 Jan;158(1):67-75.e1. Epub 2019 Aug 31 doi: 10.1053/j.gastro.2019.07.064. PMID: 31479658
Retroperitoneal fibrosis.
Pipitone N, Vaglio A, Salvarani C
Best Pract Res Clin Rheumatol 2012 Aug;26(4):439-48. doi: 10.1016/j.berh.2012.07.004. PMID: 23040359

Therapy

Epidural corticosteroid injections for lumbosacral radicular pain.
Oliveira CB, Maher CG, Ferreira ML, Hancock MJ, Oliveira VC, McLachlan AJ, Koes BW, Ferreira PH, Cohen SP, Pinto RZ
Cochrane Database Syst Rev 2020 Apr 9;4(4):CD013577. doi: 10.1002/14651858.CD013577. PMID: 32271952Free PMC Article
Median arcuate ligament syndrome.
Goodall R, Langridge B, Onida S, Ellis M, Lane T, Davies AH
J Vasc Surg 2020 Jun;71(6):2170-2176. Epub 2019 Dec 25 doi: 10.1016/j.jvs.2019.11.012. PMID: 31882314
American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis.
Baron TH, DiMaio CJ, Wang AY, Morgan KA
Gastroenterology 2020 Jan;158(1):67-75.e1. Epub 2019 Aug 31 doi: 10.1053/j.gastro.2019.07.064. PMID: 31479658
Pelvic congestion syndrome and pelvic varicosities.
Koo S, Fan CM
Tech Vasc Interv Radiol 2014 Jun;17(2):90-5. doi: 10.1053/j.tvir.2014.02.005. PMID: 24840963
Retroperitoneal fibrosis.
Pipitone N, Vaglio A, Salvarani C
Best Pract Res Clin Rheumatol 2012 Aug;26(4):439-48. doi: 10.1016/j.berh.2012.07.004. PMID: 23040359

Prognosis

Ultrasound-Guided Diagnosis and Treatment of Meralgia Paresthetica.
Onat SS, Ata AM, Ozcakar L
Pain Physician 2016 May;19(4):E667-9. PMID: 27228536
IgG4-related disease: a rheumatologist's perspective.
Soliotis F, Mavragani CP, Plastiras SC, Rontogianni D, Skopouli FN, Moutsopoulos HM
Clin Exp Rheumatol 2014 Sep-Oct;32(5):724-7. Epub 2014 Jul 28 PMID: 25068679
The hot foot syndrome: Evans' sign and the old way.
Evans RJ, Watson CP
Pain Res Manag 2012 Jan-Feb;17(1):31-4. doi: 10.1155/2012/658730. PMID: 22518365Free PMC Article
Growing teratoma syndrome.
Karam JA, Raj GV
Urology 2009 Oct;74(4):783-4. Epub 2009 Aug 3 doi: 10.1016/j.urology.2009.03.026. PMID: 19647298
Pancreatic cancer: from bench to 5-year survival.
Kleeff J, Michalski C, Friess H, Büchler MW
Pancreas 2006 Aug;33(2):111-8. doi: 10.1097/01.mpa.0000229010.62538.f2. PMID: 16868475

Clinical prediction guides

Endovascular management of nutcracker syndrome in an adolescent patient population.
Cronan JC, Hawkins CM, Kennedy SS, Marshall KW, Rostad BS, Gill AE
Pediatr Radiol 2021 Jul;51(8):1487-1496. Epub 2021 Mar 11 doi: 10.1007/s00247-021-04986-0. PMID: 33704542
Stenting for chronic obstructive venous disease: A current comprehensive meta-analysis and systematic review.
Wen-da W, Yu Z, Yue-Xin C
Phlebology 2016 Jul;31(6):376-89. Epub 2015 Jul 22 doi: 10.1177/0268355515596474. PMID: 26205370
IgG4-related disease: a rheumatologist's perspective.
Soliotis F, Mavragani CP, Plastiras SC, Rontogianni D, Skopouli FN, Moutsopoulos HM
Clin Exp Rheumatol 2014 Sep-Oct;32(5):724-7. Epub 2014 Jul 28 PMID: 25068679
The hot foot syndrome: Evans' sign and the old way.
Evans RJ, Watson CP
Pain Res Manag 2012 Jan-Feb;17(1):31-4. doi: 10.1155/2012/658730. PMID: 22518365Free PMC Article
Diagnosis and surgical treatment of nutcracker syndrome: a single-center experience.
Wang L, Yi L, Yang L, Liu Z, Rao J, Liu L, Yang J
Urology 2009 Apr;73(4):871-6. Epub 2009 Feb 4 doi: 10.1016/j.urology.2008.11.043. PMID: 19193424

Recent systematic reviews

Epidural corticosteroid injections for lumbosacral radicular pain.
Oliveira CB, Maher CG, Ferreira ML, Hancock MJ, Oliveira VC, McLachlan AJ, Koes BW, Ferreira PH, Cohen SP, Pinto RZ
Cochrane Database Syst Rev 2020 Apr 9;4(4):CD013577. doi: 10.1002/14651858.CD013577. PMID: 32271952Free PMC Article
Stenting for chronic obstructive venous disease: A current comprehensive meta-analysis and systematic review.
Wen-da W, Yu Z, Yue-Xin C
Phlebology 2016 Jul;31(6):376-89. Epub 2015 Jul 22 doi: 10.1177/0268355515596474. PMID: 26205370

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