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Increased Bone Remodeling

MedGen UID:
1709969
Concept ID:
C5237710
Finding

Definition

Increase in the removal of mineralized bone matrix and/or mature bone and the formation of new bone. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased Bone Remodeling

Professional guidelines

PubMed

Rajput S, Dutta A, Rajender S, Mithal A, Chattopadhyay N
Front Endocrinol (Lausanne) 2023;14:1098841. Epub 2023 Feb 2 doi: 10.3389/fendo.2023.1098841. PMID: 36817591Free PMC Article
Ferrari S, Bianchi ML, Eisman JA, Foldes AJ, Adami S, Wahl DA, Stepan JJ, de Vernejoul MC, Kaufman JM; IOF Committee of Scientific Advisors Working Group on Osteoporosis Pathophysiology
Osteoporos Int 2012 Dec;23(12):2735-48. Epub 2012 Jun 9 doi: 10.1007/s00198-012-2030-x. PMID: 22684497
Tiegs RD
Clin Ther 1997 Nov-Dec;19(6):1309-29; discussion 1523-4. doi: 10.1016/s0149-2918(97)80007-0. PMID: 9444442

Recent clinical studies

Etiology

Nieckula P, Stempniewicz A, Tubaja M
Dent Med Probl 2018 Oct-Dec;55(4):425-429. doi: 10.17219/dmp/99021. PMID: 30521152
Loef M, van Beest S, Kroon FPB, Bloem JL, Dekkers OM, Reijnierse M, Schoones JW, Kloppenburg M
Osteoarthritis Cartilage 2018 Aug;26(8):992-1002. Epub 2018 May 17 doi: 10.1016/j.joca.2018.05.007. PMID: 29777863
Ferrari S, Bianchi ML, Eisman JA, Foldes AJ, Adami S, Wahl DA, Stepan JJ, de Vernejoul MC, Kaufman JM; IOF Committee of Scientific Advisors Working Group on Osteoporosis Pathophysiology
Osteoporos Int 2012 Dec;23(12):2735-48. Epub 2012 Jun 9 doi: 10.1007/s00198-012-2030-x. PMID: 22684497
Nickolas TL, Cremers S, Zhang A, Thomas V, Stein E, Cohen A, Chauncey R, Nikkel L, Yin MT, Liu XS, Boutroy S, Staron RB, Leonard MB, McMahon DJ, Dworakowski E, Shane E
J Am Soc Nephrol 2011 Aug;22(8):1560-72. Epub 2011 Jul 22 doi: 10.1681/ASN.2010121275. PMID: 21784896Free PMC Article
Gennari C, Martini G, Nuti R
Aging (Milano) 1998 Jun;10(3):214-24. doi: 10.1007/BF03339655. PMID: 9801731

Diagnosis

Michou L, Gamache P, Guertin JR, Tarride JE, Brown JP, Jean S
Bone 2023 Nov;176:116895. Epub 2023 Sep 6 doi: 10.1016/j.bone.2023.116895. PMID: 37683713
Hsu E
Curr Opin Endocrinol Diabetes Obes 2019 Dec;26(6):329-334. doi: 10.1097/MED.0000000000000503. PMID: 31574000
Nickolas TL, Cremers S, Zhang A, Thomas V, Stein E, Cohen A, Chauncey R, Nikkel L, Yin MT, Liu XS, Boutroy S, Staron RB, Leonard MB, McMahon DJ, Dworakowski E, Shane E
J Am Soc Nephrol 2011 Aug;22(8):1560-72. Epub 2011 Jul 22 doi: 10.1681/ASN.2010121275. PMID: 21784896Free PMC Article
Schauwecker DS
AJR Am J Roentgenol 1992 Jan;158(1):9-18. doi: 10.2214/ajr.158.1.1727365. PMID: 1727365
Merkow RL, Lane JM
Orthop Clin North Am 1990 Jan;21(1):171-89. PMID: 2404234

Therapy

Cheung AS, Hoermann R, Ghasem-Zadeh A, Tinson AJ, Ly V, Milevski SV, Joon DL, Zajac JD, Seeman E, Grossmann M
J Bone Miner Res 2020 Oct;35(10):1871-1880. Epub 2020 Jul 6 doi: 10.1002/jbmr.4106. PMID: 32542695
Hsu E
Curr Opin Endocrinol Diabetes Obes 2019 Dec;26(6):329-334. doi: 10.1097/MED.0000000000000503. PMID: 31574000
Nieckula P, Stempniewicz A, Tubaja M
Dent Med Probl 2018 Oct-Dec;55(4):425-429. doi: 10.17219/dmp/99021. PMID: 30521152
Whitmarsh T, Treece GM, Gee AH, Poole KE
J Bone Miner Res 2015 Jul;30(7):1309-18. doi: 10.1002/jbmr.2454. PMID: 25639838
Heaney RP
J Am Coll Nutr 2006 Jun;25(3 Suppl):271S-276S. doi: 10.1080/07315724.2006.10719577. PMID: 16772639

Prognosis

Xie D, Bai Z, Zhou G, Li K, Ding J, Zhang H, Jiang J
Chem Biol Drug Des 2023 Dec;102(6):1478-1488. Epub 2023 Sep 15 doi: 10.1111/cbdd.14339. PMID: 37712455
Michou L, Gamache P, Guertin JR, Tarride JE, Brown JP, Jean S
Bone 2023 Nov;176:116895. Epub 2023 Sep 6 doi: 10.1016/j.bone.2023.116895. PMID: 37683713
Loef M, van Beest S, Kroon FPB, Bloem JL, Dekkers OM, Reijnierse M, Schoones JW, Kloppenburg M
Osteoarthritis Cartilage 2018 Aug;26(8):992-1002. Epub 2018 May 17 doi: 10.1016/j.joca.2018.05.007. PMID: 29777863
Whitmarsh T, Treece GM, Gee AH, Poole KE
J Bone Miner Res 2015 Jul;30(7):1309-18. doi: 10.1002/jbmr.2454. PMID: 25639838
Guignard S, Job-Deslandre C, Sayag-Boukris V, Kahan A
Joint Bone Spine 2002 Jun;69(4):392-6. doi: 10.1016/s1297-319x(02)00419-0. PMID: 12184437

Clinical prediction guides

Michou L, Gamache P, Guertin JR, Tarride JE, Brown JP, Jean S
Bone 2023 Nov;176:116895. Epub 2023 Sep 6 doi: 10.1016/j.bone.2023.116895. PMID: 37683713
Wothe JK, Aidoo R, McEachron KR, Harindhanavudhi T, Trikudanathan G, Freeman ML, Kirchner V, Pruett TL, Beilman GJ, Hodges JS, Bellin MD
Pancreatology 2021 Dec;21(8):1491-1497. Epub 2021 Sep 4 doi: 10.1016/j.pan.2021.08.013. PMID: 34538580Free PMC Article
Loef M, van Beest S, Kroon FPB, Bloem JL, Dekkers OM, Reijnierse M, Schoones JW, Kloppenburg M
Osteoarthritis Cartilage 2018 Aug;26(8):992-1002. Epub 2018 May 17 doi: 10.1016/j.joca.2018.05.007. PMID: 29777863
Ferrari S, Bianchi ML, Eisman JA, Foldes AJ, Adami S, Wahl DA, Stepan JJ, de Vernejoul MC, Kaufman JM; IOF Committee of Scientific Advisors Working Group on Osteoporosis Pathophysiology
Osteoporos Int 2012 Dec;23(12):2735-48. Epub 2012 Jun 9 doi: 10.1007/s00198-012-2030-x. PMID: 22684497
Nickolas TL, Cremers S, Zhang A, Thomas V, Stein E, Cohen A, Chauncey R, Nikkel L, Yin MT, Liu XS, Boutroy S, Staron RB, Leonard MB, McMahon DJ, Dworakowski E, Shane E
J Am Soc Nephrol 2011 Aug;22(8):1560-72. Epub 2011 Jul 22 doi: 10.1681/ASN.2010121275. PMID: 21784896Free PMC Article

Recent systematic reviews

Rajput S, Dutta A, Rajender S, Mithal A, Chattopadhyay N
Front Endocrinol (Lausanne) 2023;14:1098841. Epub 2023 Feb 2 doi: 10.3389/fendo.2023.1098841. PMID: 36817591Free PMC Article
Loef M, van Beest S, Kroon FPB, Bloem JL, Dekkers OM, Reijnierse M, Schoones JW, Kloppenburg M
Osteoarthritis Cartilage 2018 Aug;26(8):992-1002. Epub 2018 May 17 doi: 10.1016/j.joca.2018.05.007. PMID: 29777863

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