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Increased cystatin C level

MedGen UID:
1709975
•Concept ID:
C5397989
•
Finding
HPO: HP:0032998

Definition

A elevated concentration of cystatin C in the blood circulation. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased cystatin C level

Professional guidelines

PubMed

Assessment of renal function during high-dose methotrexate treatment in children with acute lymphoblastic leukemia.
Ylinen E, Jahnukainen K, Saarinen-Pihkala UM, Jahnukainen T
Pediatr Blood Cancer 2014 Dec;61(12):2199-202. Epub 2014 Aug 31 doi: 10.1002/pbc.25137. PMID: 25174822

Recent clinical studies

Etiology

Increased Cystatin C Level in ST-Elevation Myocardial Infarction Predisposes the Prognosis of Angioplasty.
Shen G, Zhu H, Ding H, Sun C, Zhou K, Fan Y, Li T, Men M, Chen Y, Lu Q, Ma A
Am J Med Sci 2018 Jun;355(6):530-536. Epub 2018 Mar 5 doi: 10.1016/j.amjms.2018.03.003. PMID: 29891036
Cystatin C as a predictor factor in patients with renal cell carcinoma treated by everolimus.
Bodnar L, Stec R, Dzierżanowska M, Synowiec A, Cierniak S, Kade G, Szczylik C
Cancer Chemother Pharmacol 2016 Aug;78(2):295-304. Epub 2016 Jun 20 doi: 10.1007/s00280-016-3084-9. PMID: 27324020
Significant correlation between cystatin C, cerebral infarction, and potential biomarker for increased risk of stroke.
Zeng Q, Lin K, Yao M, Wei L
Curr Neurovasc Res 2015;12(1):40-6. doi: 10.2174/1567202612666150102150941. PMID: 25557377
Relationship between oxidative stress parameters and cystatin C levels in patients with severe preeclampsia.
Yalcin S, Ulas T, Eren MA, Aydogan H, Camuzcuoglu A, Kucuk A, Yuce HH, Demir ME, Vural M, Aksoy N
Medicina (Kaunas) 2013;49(3):118-23. PMID: 23893055
Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons.
Choi A, Scherzer R, Bacchetti P, Tien PC, Saag MS, Gibert CL, Szczech LA, Grunfeld C, Shlipak MG
Am J Kidney Dis 2010 Nov;56(5):872-82. Epub 2010 Aug 14 doi: 10.1053/j.ajkd.2010.05.019. PMID: 20709438Free PMC Article

Diagnosis

Independent associations of urinary albumin-to-creatinine ratio and serum cystatin C with carotid intima-media thickness in community-living Taiwanese adults.
Liu CS, Li CI, Guo YC, Lin CH, Lin WY, Liu CH, Wang MC, Yang CW, Yang SY, Li TC, Lin CC
BMC Nephrol 2020 Oct 31;21(1):454. doi: 10.1186/s12882-020-02123-x. PMID: 33129312Free PMC Article
Cystatin C as a predictor factor in patients with renal cell carcinoma treated by everolimus.
Bodnar L, Stec R, Dzierżanowska M, Synowiec A, Cierniak S, Kade G, Szczylik C
Cancer Chemother Pharmacol 2016 Aug;78(2):295-304. Epub 2016 Jun 20 doi: 10.1007/s00280-016-3084-9. PMID: 27324020

Therapy

Cystatin C as a predictor factor in patients with renal cell carcinoma treated by everolimus.
Bodnar L, Stec R, Dzierżanowska M, Synowiec A, Cierniak S, Kade G, Szczylik C
Cancer Chemother Pharmacol 2016 Aug;78(2):295-304. Epub 2016 Jun 20 doi: 10.1007/s00280-016-3084-9. PMID: 27324020

Prognosis

Increased Cystatin C Level in ST-Elevation Myocardial Infarction Predisposes the Prognosis of Angioplasty.
Shen G, Zhu H, Ding H, Sun C, Zhou K, Fan Y, Li T, Men M, Chen Y, Lu Q, Ma A
Am J Med Sci 2018 Jun;355(6):530-536. Epub 2018 Mar 5 doi: 10.1016/j.amjms.2018.03.003. PMID: 29891036
Cystatin C as a predictor factor in patients with renal cell carcinoma treated by everolimus.
Bodnar L, Stec R, Dzierżanowska M, Synowiec A, Cierniak S, Kade G, Szczylik C
Cancer Chemother Pharmacol 2016 Aug;78(2):295-304. Epub 2016 Jun 20 doi: 10.1007/s00280-016-3084-9. PMID: 27324020
Significant correlation between cystatin C, cerebral infarction, and potential biomarker for increased risk of stroke.
Zeng Q, Lin K, Yao M, Wei L
Curr Neurovasc Res 2015;12(1):40-6. doi: 10.2174/1567202612666150102150941. PMID: 25557377
Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons.
Choi A, Scherzer R, Bacchetti P, Tien PC, Saag MS, Gibert CL, Szczech LA, Grunfeld C, Shlipak MG
Am J Kidney Dis 2010 Nov;56(5):872-82. Epub 2010 Aug 14 doi: 10.1053/j.ajkd.2010.05.019. PMID: 20709438Free PMC Article

Clinical prediction guides

Increased Cystatin C Level in ST-Elevation Myocardial Infarction Predisposes the Prognosis of Angioplasty.
Shen G, Zhu H, Ding H, Sun C, Zhou K, Fan Y, Li T, Men M, Chen Y, Lu Q, Ma A
Am J Med Sci 2018 Jun;355(6):530-536. Epub 2018 Mar 5 doi: 10.1016/j.amjms.2018.03.003. PMID: 29891036
Cystatin C as a predictor factor in patients with renal cell carcinoma treated by everolimus.
Bodnar L, Stec R, Dzierżanowska M, Synowiec A, Cierniak S, Kade G, Szczylik C
Cancer Chemother Pharmacol 2016 Aug;78(2):295-304. Epub 2016 Jun 20 doi: 10.1007/s00280-016-3084-9. PMID: 27324020
Significant correlation between cystatin C, cerebral infarction, and potential biomarker for increased risk of stroke.
Zeng Q, Lin K, Yao M, Wei L
Curr Neurovasc Res 2015;12(1):40-6. doi: 10.2174/1567202612666150102150941. PMID: 25557377
Cystatin C, albuminuria, and 5-year all-cause mortality in HIV-infected persons.
Choi A, Scherzer R, Bacchetti P, Tien PC, Saag MS, Gibert CL, Szczech LA, Grunfeld C, Shlipak MG
Am J Kidney Dis 2010 Nov;56(5):872-82. Epub 2010 Aug 14 doi: 10.1053/j.ajkd.2010.05.019. PMID: 20709438Free PMC Article

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