U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Syncope due to Pulmonary Hypertension

MedGen UID:
1710535
Concept ID:
C5238880
Sign or Symptom

Definition

A condition in which syncope occurs associated with a sudden and severe increase in pulmonary vascular resistance. (ACC-AHA) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSyncope due to Pulmonary Hypertension

Professional guidelines

PubMed

Thenappan T, Ormiston ML, Ryan JJ, Archer SL
BMJ 2018 Mar 14;360:j5492. doi: 10.1136/bmj.j5492. PMID: 29540357Free PMC Article
Poms A, Kingman M
Crit Care Nurse 2011 Dec;31(6):e1-10. doi: 10.4037/ccn2011153. PMID: 22135338
Scarlett M, McGaw C, Aquart-Stewart A
West Indian Med J 2009 Mar;58(2):153-9. PMID: 21866602

Recent clinical studies

Etiology

Jaïs X, Brenot P, Bouvaist H, Jevnikar M, Canuet M, Chabanne C, Chaouat A, Cottin V, De Groote P, Favrolt N, Horeau-Langlard D, Magro P, Savale L, Prévot G, Renard S, Sitbon O, Parent F, Trésorier R, Tromeur C, Piedvache C, Grimaldi L, Fadel E, Montani D, Humbert M, Simonneau G
Lancet Respir Med 2022 Oct;10(10):961-971. Epub 2022 Aug 1 doi: 10.1016/S2213-2600(22)00214-4. PMID: 35926542
Thenappan T, Ormiston ML, Ryan JJ, Archer SL
BMJ 2018 Mar 14;360:j5492. doi: 10.1136/bmj.j5492. PMID: 29540357Free PMC Article
Gawinecka J, Schönrath F, von Eckardstein A
Swiss Med Wkly 2017;147:w14489. Epub 2017 Aug 25 doi: 10.4414/smw.2017.14489. PMID: 28871571
Ghofrani HA, Galiè N, Grimminger F, Grünig E, Humbert M, Jing ZC, Keogh AM, Langleben D, Kilama MO, Fritsch A, Neuser D, Rubin LJ; PATENT-1 Study Group
N Engl J Med 2013 Jul 25;369(4):330-40. doi: 10.1056/NEJMoa1209655. PMID: 23883378
Ghofrani HA, D'Armini AM, Grimminger F, Hoeper MM, Jansa P, Kim NH, Mayer E, Simonneau G, Wilkins MR, Fritsch A, Neuser D, Weimann G, Wang C; CHEST-1 Study Group
N Engl J Med 2013 Jul 25;369(4):319-29. doi: 10.1056/NEJMoa1209657. PMID: 23883377

Diagnosis

Seitler S, Dimopoulos K, Ernst S, Price LC
Semin Respir Crit Care Med 2023 Dec;44(6):777-796. Epub 2023 Aug 18 doi: 10.1055/s-0043-1770120. PMID: 37595615
Jaïs X, Brenot P, Bouvaist H, Jevnikar M, Canuet M, Chabanne C, Chaouat A, Cottin V, De Groote P, Favrolt N, Horeau-Langlard D, Magro P, Savale L, Prévot G, Renard S, Sitbon O, Parent F, Trésorier R, Tromeur C, Piedvache C, Grimaldi L, Fadel E, Montani D, Humbert M, Simonneau G
Lancet Respir Med 2022 Oct;10(10):961-971. Epub 2022 Aug 1 doi: 10.1016/S2213-2600(22)00214-4. PMID: 35926542
Thenappan T, Ormiston ML, Ryan JJ, Archer SL
BMJ 2018 Mar 14;360:j5492. doi: 10.1136/bmj.j5492. PMID: 29540357Free PMC Article
Gawinecka J, Schönrath F, von Eckardstein A
Swiss Med Wkly 2017;147:w14489. Epub 2017 Aug 25 doi: 10.4414/smw.2017.14489. PMID: 28871571
Rashid A, Lehrman S, Romano P, Frishman W, Dobkin J, Reichel J
Heart Dis 2000 Nov-Dec;2(6):422-30. PMID: 11728293

Therapy

Jaïs X, Brenot P, Bouvaist H, Jevnikar M, Canuet M, Chabanne C, Chaouat A, Cottin V, De Groote P, Favrolt N, Horeau-Langlard D, Magro P, Savale L, Prévot G, Renard S, Sitbon O, Parent F, Trésorier R, Tromeur C, Piedvache C, Grimaldi L, Fadel E, Montani D, Humbert M, Simonneau G
Lancet Respir Med 2022 Oct;10(10):961-971. Epub 2022 Aug 1 doi: 10.1016/S2213-2600(22)00214-4. PMID: 35926542
Paone S, Clarkson L, Sin B, Punnapuzha S
Am J Emerg Med 2018 Aug;36(8):1526.e5-1526.e7. Epub 2018 May 10 doi: 10.1016/j.ajem.2018.05.013. PMID: 29776826
Ghofrani HA, Galiè N, Grimminger F, Grünig E, Humbert M, Jing ZC, Keogh AM, Langleben D, Kilama MO, Fritsch A, Neuser D, Rubin LJ; PATENT-1 Study Group
N Engl J Med 2013 Jul 25;369(4):330-40. doi: 10.1056/NEJMoa1209655. PMID: 23883378
Ghofrani HA, D'Armini AM, Grimminger F, Hoeper MM, Jansa P, Kim NH, Mayer E, Simonneau G, Wilkins MR, Fritsch A, Neuser D, Weimann G, Wang C; CHEST-1 Study Group
N Engl J Med 2013 Jul 25;369(4):319-29. doi: 10.1056/NEJMoa1209657. PMID: 23883377
Prakash A, Perry CM
Am J Cardiovasc Drugs 2002;2(5):335-43; discussion 343. doi: 10.2165/00129784-200202050-00006. PMID: 14727963

Prognosis

Jaïs X, Brenot P, Bouvaist H, Jevnikar M, Canuet M, Chabanne C, Chaouat A, Cottin V, De Groote P, Favrolt N, Horeau-Langlard D, Magro P, Savale L, Prévot G, Renard S, Sitbon O, Parent F, Trésorier R, Tromeur C, Piedvache C, Grimaldi L, Fadel E, Montani D, Humbert M, Simonneau G
Lancet Respir Med 2022 Oct;10(10):961-971. Epub 2022 Aug 1 doi: 10.1016/S2213-2600(22)00214-4. PMID: 35926542
Jiang X, Zhu YJ, Zhou YP, Peng FH, Wang L, Ma W, Cao YS, Pan X, Zhang GC, Zhang F, Fan FL, Wu BX, Huang W, Yang ZW, Hong C, Li MT, Wang YN, Xu XQ, Wang DL, Zhang SY, Jing ZC
Eur Heart J 2021 Nov 7;42(42):4298-4305. doi: 10.1093/eurheartj/ehab599. PMID: 34506618
Wu DC, Zhang HD, Jing ZC
Curr Hypertens Rep 2013 Dec;15(6):606-13. doi: 10.1007/s11906-013-0399-3. PMID: 24163011
Limsukon A, Saeed AI, Ramasamy V, Nalamati J, Dhuper S
Mt Sinai J Med 2006 Nov;73(7):1037-44. PMID: 17195895
Rashid A, Lehrman S, Romano P, Frishman W, Dobkin J, Reichel J
Heart Dis 2000 Nov-Dec;2(6):422-30. PMID: 11728293

Clinical prediction guides

Jaïs X, Brenot P, Bouvaist H, Jevnikar M, Canuet M, Chabanne C, Chaouat A, Cottin V, De Groote P, Favrolt N, Horeau-Langlard D, Magro P, Savale L, Prévot G, Renard S, Sitbon O, Parent F, Trésorier R, Tromeur C, Piedvache C, Grimaldi L, Fadel E, Montani D, Humbert M, Simonneau G
Lancet Respir Med 2022 Oct;10(10):961-971. Epub 2022 Aug 1 doi: 10.1016/S2213-2600(22)00214-4. PMID: 35926542
Jiang X, Zhu YJ, Zhou YP, Peng FH, Wang L, Ma W, Cao YS, Pan X, Zhang GC, Zhang F, Fan FL, Wu BX, Huang W, Yang ZW, Hong C, Li MT, Wang YN, Xu XQ, Wang DL, Zhang SY, Jing ZC
Eur Heart J 2021 Nov 7;42(42):4298-4305. doi: 10.1093/eurheartj/ehab599. PMID: 34506618
Ghofrani HA, Galiè N, Grimminger F, Grünig E, Humbert M, Jing ZC, Keogh AM, Langleben D, Kilama MO, Fritsch A, Neuser D, Rubin LJ; PATENT-1 Study Group
N Engl J Med 2013 Jul 25;369(4):330-40. doi: 10.1056/NEJMoa1209655. PMID: 23883378
Ghofrani HA, D'Armini AM, Grimminger F, Hoeper MM, Jansa P, Kim NH, Mayer E, Simonneau G, Wilkins MR, Fritsch A, Neuser D, Weimann G, Wang C; CHEST-1 Study Group
N Engl J Med 2013 Jul 25;369(4):319-29. doi: 10.1056/NEJMoa1209657. PMID: 23883377
Barst RJ, Ertel SI, Beghetti M, Ivy DD
Eur Respir J 2011 Mar;37(3):665-77. doi: 10.1183/09031936.00056110. PMID: 21357924Free PMC Article

Recent systematic reviews

Zhang Y, Qiu Y, Luo J, Zhang J, Yan Q
Tex Heart Inst J 2023 Aug 11;50(4) doi: 10.14503/THIJ-23-8113. PMID: 37577766Free PMC Article
Lovatt S, Wong CW, Schwarz K, Borovac JA, Lo T, Gunning M, Phan T, Patwala A, Barker D, Mallen CD, Kwok CS
Am J Emerg Med 2022 Mar;53:16-22. Epub 2021 Dec 4 doi: 10.1016/j.ajem.2021.11.047. PMID: 34968970
Zhou Y, Shao L, Ruan W, Jin J, Xu H, Ying K, Wu X
Medicine (Baltimore) 2019 Feb;98(6):e14437. doi: 10.1097/MD.0000000000014437. PMID: 30732204Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...