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Refractory Skin Squamous Cell Carcinoma

MedGen UID:
1710593
Concept ID:
C5237413
Neoplastic Process

Definition

Skin squamous cell carcinoma that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Skin Squamous Cell Carcinoma

Professional guidelines

PubMed

Jansen P, Lodde GC, Griewank KG, Hadaschik E, Roesch A, Ugurel S, Zimmer L, Livingstone E, Schadendorf D
J Eur Acad Dermatol Venereol 2022 Jan;36 Suppl 1:29-34. doi: 10.1111/jdv.17404. PMID: 34855242
Gellrich FF, Hüning S, Beissert S, Eigentler T, Stockfleth E, Gutzmer R, Meier F
J Eur Acad Dermatol Venereol 2019 Dec;33 Suppl 8:38-43. doi: 10.1111/jdv.16024. PMID: 31833610
Fistarol SK, Itin PH
Am J Clin Dermatol 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4. PMID: 23329078Free PMC Article

Recent clinical studies

Etiology

Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes)
J Eur Acad Dermatol Venereol 2024 Jun;38(6):1024-1047. Epub 2024 Mar 7 doi: 10.1111/jdv.19897. PMID: 38451047
Gellrich FF, Hüning S, Beissert S, Eigentler T, Stockfleth E, Gutzmer R, Meier F
J Eur Acad Dermatol Venereol 2019 Dec;33 Suppl 8:38-43. doi: 10.1111/jdv.16024. PMID: 31833610
Chen WC, Chu PY, Lee YT, Lu WB, Liu CY, Chang PM, Yang MH
Medicine (Baltimore) 2017 Dec;96(52):e9519. doi: 10.1097/MD.0000000000009519. PMID: 29384959Free PMC Article
Fistarol SK, Itin PH
Am J Clin Dermatol 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4. PMID: 23329078Free PMC Article
Ho VC
Br J Dermatol 2004 May;150 Suppl 67:1-10. doi: 10.1111/j.0366-077X.2004.05950.x. PMID: 15115440

Diagnosis

Kandolf L, Peris K, Malvehy J, Mosterd K, Heppt MV, Fargnoli MC, Berking C, Arenberger P, Bylaite-Bučinskiene M, Del Marmol V, Dirschka T, Dreno B, Forsea AM, Harwood CA, Hauschild A, Heerfordt IM, Kauffman R, Kelleners-Smeets N, Lallas A, Lebbe C, Leiter U, Longo C, Mijušković Ž, Pellacani G, Puig S, Saiag P, Šitum M, Stockfleth E, Salavastru C, Stratigos A, Zalaudek I, Garbe C; European Association of Dermato‐Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes)
J Eur Acad Dermatol Venereol 2024 Jun;38(6):1024-1047. Epub 2024 Mar 7 doi: 10.1111/jdv.19897. PMID: 38451047
Yan Z, Liang P
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Aug 28;47(8):1154-1162. doi: 10.11817/j.issn.1672-7347.2022.210332. PMID: 36097784Free PMC Article
Spencer A, Watchorn RE, Kravvas G, Ben-Salha I, Haider A, Francis N, Freeman A, Alnajjar HM, Muneer A, Bunker CB
J Eur Acad Dermatol Venereol 2022 Oct;36(10):1851-1856. Epub 2022 Jun 29 doi: 10.1111/jdv.18328. PMID: 35695159
Seger EW, Tarantino IS, Neill BC, Wang T
J Cutan Med Surg 2020 Jan/Feb;24(1):41-46. Epub 2019 Oct 8 doi: 10.1177/1203475419882336. PMID: 31591899
Fistarol SK, Itin PH
Am J Clin Dermatol 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4. PMID: 23329078Free PMC Article

Therapy

Jhawar SR, Wang SJ, Thandoni A, Bommareddy PK, Newman JH, Marzo AL, Kuzel TM, Gupta V, Reiser J, Daniels P, Schiff D, Mitchell D, LeBoeuf NR, Simmons C, Goyal S, Lasfar A, Guevara-Patino JA, Haffty BG, Kaufman HL, Silk AW, Zloza A, Giurini EF
J Immunother Cancer 2023 Jul;11(7) doi: 10.1136/jitc-2023-006780. PMID: 37433716Free PMC Article
Shalhout SZ, Emerick KS, Kaufman HL, Miller DM
Curr Oncol Rep 2021 Aug 27;23(11):125. doi: 10.1007/s11912-021-01120-z. PMID: 34448958Free PMC Article
Barrios DM, Do MH, Phillips GS, Postow MA, Akaike T, Nghiem P, Lacouture ME
J Am Acad Dermatol 2020 Nov;83(5):1239-1253. Epub 2020 May 24 doi: 10.1016/j.jaad.2020.03.131. PMID: 32461079Free PMC Article
Gellrich FF, Hüning S, Beissert S, Eigentler T, Stockfleth E, Gutzmer R, Meier F
J Eur Acad Dermatol Venereol 2019 Dec;33 Suppl 8:38-43. doi: 10.1111/jdv.16024. PMID: 31833610
Fistarol SK, Itin PH
Am J Clin Dermatol 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4. PMID: 23329078Free PMC Article

Prognosis

Yan Z, Liang P
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Aug 28;47(8):1154-1162. doi: 10.11817/j.issn.1672-7347.2022.210332. PMID: 36097784Free PMC Article
Spencer A, Watchorn RE, Kravvas G, Ben-Salha I, Haider A, Francis N, Freeman A, Alnajjar HM, Muneer A, Bunker CB
J Eur Acad Dermatol Venereol 2022 Oct;36(10):1851-1856. Epub 2022 Jun 29 doi: 10.1111/jdv.18328. PMID: 35695159
Ferrarotto R, Sousa LG, Qing Y, Kaya D, Stephen B, Jain D, Bell D, Pant S, Tsimberidou AM, Janku F, Blumenschein G, Glisson BS, Ahnert JR, Piha-Paul SA, Lee JJ, Wong MK, Lu C, Meric-Bernstam F, Naing A
Adv Ther 2021 Aug;38(8):4581-4591. Epub 2021 Jul 9 doi: 10.1007/s12325-021-01807-6. PMID: 34241781
Barrios DM, Do MH, Phillips GS, Postow MA, Akaike T, Nghiem P, Lacouture ME
J Am Acad Dermatol 2020 Nov;83(5):1239-1253. Epub 2020 May 24 doi: 10.1016/j.jaad.2020.03.131. PMID: 32461079Free PMC Article
Ferrarotto R, Gold KA
Expert Opin Investig Drugs 2014 Jan;23(1):135-43. Epub 2013 Nov 25 doi: 10.1517/13543784.2014.858696. PMID: 24266694

Clinical prediction guides

Yan Z, Liang P
Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Aug 28;47(8):1154-1162. doi: 10.11817/j.issn.1672-7347.2022.210332. PMID: 36097784Free PMC Article
Spencer A, Watchorn RE, Kravvas G, Ben-Salha I, Haider A, Francis N, Freeman A, Alnajjar HM, Muneer A, Bunker CB
J Eur Acad Dermatol Venereol 2022 Oct;36(10):1851-1856. Epub 2022 Jun 29 doi: 10.1111/jdv.18328. PMID: 35695159
Kao HF, Liao BC, Huang YL, Huang HC, Chen CN, Chen TC, Hong YJ, Chan CY, Chia JS, Hong RL
Clin Cancer Res 2022 Apr 14;28(8):1560-1571. doi: 10.1158/1078-0432.CCR-21-3025. PMID: 35046059Free PMC Article
Barrios DM, Do MH, Phillips GS, Postow MA, Akaike T, Nghiem P, Lacouture ME
J Am Acad Dermatol 2020 Nov;83(5):1239-1253. Epub 2020 May 24 doi: 10.1016/j.jaad.2020.03.131. PMID: 32461079Free PMC Article
Gatti V, Fierro C, Annicchiarico-Petruzzelli M, Melino G, Peschiaroli A
Mol Oncol 2019 May;13(5):981-1001. Epub 2019 Mar 22 doi: 10.1002/1878-0261.12473. PMID: 30845357Free PMC Article

Recent systematic reviews

Seger EW, Tarantino IS, Neill BC, Wang T
J Cutan Med Surg 2020 Jan/Feb;24(1):41-46. Epub 2019 Oct 8 doi: 10.1177/1203475419882336. PMID: 31591899

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