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Hereditary Colorectal Cancer Syndrome

MedGen UID:
1712465
Concept ID:
C5237209
Neoplastic Process

Definition

A group of hereditary neoplastic syndromes that affect the colon and rectum. Included in this grouping are hereditary nonpolyposis colorectal cancer (HNPCCC) , familial adenomatous polyposis (FAP), and the hamartomatous polyposis syndromes. [from NCI]

Professional guidelines

PubMed

Cunningham LA, Gasior A, Kalady MF
Surg Oncol Clin N Am 2022 Apr;31(2):307-319. Epub 2022 Mar 9 doi: 10.1016/j.soc.2021.11.010. PMID: 35351280
Nallamilli BRR, Hegde M
Curr Protoc Hum Genet 2017 Jul 11;94:10.12.1-10.12.23. doi: 10.1002/cphg.40. PMID: 28696559
Weissman SM, Bellcross C, Bittner CC, Freivogel ME, Haidle JL, Kaurah P, Leininger A, Palaniappan S, Steenblock K, Vu TM, Daniels MS
J Genet Couns 2011 Feb;20(1):5-19. Epub 2010 Oct 8 doi: 10.1007/s10897-010-9325-x. PMID: 20931355

Recent clinical studies

Etiology

Abbass MA, Church J
J Surg Oncol 2023 Jun;127(8):1259-1263. doi: 10.1002/jso.27318. PMID: 37222690
Areia M, Mori Y, Correale L, Repici A, Bretthauer M, Sharma P, Taveira F, Spadaccini M, Antonelli G, Ebigbo A, Kudo SE, Arribas J, Barua I, Kaminski MF, Messmann H, Rex DK, Dinis-Ribeiro M, Hassan C
Lancet Digit Health 2022 Jun;4(6):e436-e444. Epub 2022 Apr 13 doi: 10.1016/S2589-7500(22)00042-5. PMID: 35430151
Cunningham LA, Gasior A, Kalady MF
Surg Oncol Clin N Am 2022 Apr;31(2):307-319. Epub 2022 Mar 9 doi: 10.1016/j.soc.2021.11.010. PMID: 35351280
Maratt JK, Stoffel E
Gastrointest Endosc Clin N Am 2022 Jan;32(1):45-58. doi: 10.1016/j.giec.2021.09.002. PMID: 34798986
Kemp Bohan PM, Mankaney G, Vreeland TJ, Chick RC, Hale DF, Cindass JL, Hickerson AT, Ensley DC, Sohn V, Clifton GT, Peoples GE, Burke CA
Fam Cancer 2021 Jan;20(1):23-33. Epub 2020 Jun 8 doi: 10.1007/s10689-020-00189-y. PMID: 32507936Free PMC Article

Diagnosis

Areia M, Mori Y, Correale L, Repici A, Bretthauer M, Sharma P, Taveira F, Spadaccini M, Antonelli G, Ebigbo A, Kudo SE, Arribas J, Barua I, Kaminski MF, Messmann H, Rex DK, Dinis-Ribeiro M, Hassan C
Lancet Digit Health 2022 Jun;4(6):e436-e444. Epub 2022 Apr 13 doi: 10.1016/S2589-7500(22)00042-5. PMID: 35430151
Cunningham LA, Gasior A, Kalady MF
Surg Oncol Clin N Am 2022 Apr;31(2):307-319. Epub 2022 Mar 9 doi: 10.1016/j.soc.2021.11.010. PMID: 35351280
Long JM, Powers JM, Katona BW
Gastrointest Endosc Clin N Am 2022 Jan;32(1):95-112. doi: 10.1016/j.giec.2021.08.003. PMID: 34798989Free PMC Article
Maratt JK, Stoffel E
Gastrointest Endosc Clin N Am 2022 Jan;32(1):45-58. doi: 10.1016/j.giec.2021.09.002. PMID: 34798986
Kwak EL, Chung DC
Clin Colorectal Cancer 2007 Jan;6(5):340-4. doi: 10.3816/CCC.2007.n.002. PMID: 17311698

Therapy

Bowen CM, Walter L, Borras E, Wu W, Ozcan Z, Chang K, Bommi PV, Taggart MW, Thirumurthi S, Lynch PM, Reyes-Uribe L, Scheet PA, Sinha KM, Vilar E
Cancer Prev Res (Phila) 2021 Sep;14(9):851-862. Epub 2021 Jul 15 doi: 10.1158/1940-6207.CAPR-20-0496. PMID: 34266857Free PMC Article
Kemp Bohan PM, Mankaney G, Vreeland TJ, Chick RC, Hale DF, Cindass JL, Hickerson AT, Ensley DC, Sohn V, Clifton GT, Peoples GE, Burke CA
Fam Cancer 2021 Jan;20(1):23-33. Epub 2020 Jun 8 doi: 10.1007/s10689-020-00189-y. PMID: 32507936Free PMC Article
Herráiz M, Muñoz-Navas M
Rev Esp Enferm Dig 2009 Feb;101(2):125-32. doi: 10.4321/s1130-01082009000200006. PMID: 19335048

Prognosis

Maratt JK, Stoffel E
Gastrointest Endosc Clin N Am 2022 Jan;32(1):45-58. doi: 10.1016/j.giec.2021.09.002. PMID: 34798986
Bowen CM, Walter L, Borras E, Wu W, Ozcan Z, Chang K, Bommi PV, Taggart MW, Thirumurthi S, Lynch PM, Reyes-Uribe L, Scheet PA, Sinha KM, Vilar E
Cancer Prev Res (Phila) 2021 Sep;14(9):851-862. Epub 2021 Jul 15 doi: 10.1158/1940-6207.CAPR-20-0496. PMID: 34266857Free PMC Article
de Paula AE, Galvão HCR, Bonatelli M, Sabato C, Fernandes GC, Berardinelli GN, Andrade CEM, Neto MC, Romagnolo LGC, Campacci N, Scapulatempo-Neto C, Reis RM, Palmero EI
Cancer Genet 2021 Jun;254-255:82-91. Epub 2021 Feb 14 doi: 10.1016/j.cancergen.2021.02.003. PMID: 33647816
Galiatsatos P, Rothenmund H, Aubin S, Foulkes WD
Dig Dis Sci 2015 Aug;60(8):2246-50. Epub 2015 Mar 19 doi: 10.1007/s10620-015-3626-8. PMID: 25786861
Tejpar S, Michils G, Denys H, Van Dam K, Nik SA, Jadidizadeh A, Cassiman JJ
Acta Gastroenterol Belg 2005 Jan-Mar;68(1):5-9. PMID: 15832580

Clinical prediction guides

Maratt JK, Stoffel E
Gastrointest Endosc Clin N Am 2022 Jan;32(1):45-58. doi: 10.1016/j.giec.2021.09.002. PMID: 34798986
Bowen CM, Walter L, Borras E, Wu W, Ozcan Z, Chang K, Bommi PV, Taggart MW, Thirumurthi S, Lynch PM, Reyes-Uribe L, Scheet PA, Sinha KM, Vilar E
Cancer Prev Res (Phila) 2021 Sep;14(9):851-862. Epub 2021 Jul 15 doi: 10.1158/1940-6207.CAPR-20-0496. PMID: 34266857Free PMC Article
de Paula AE, Galvão HCR, Bonatelli M, Sabato C, Fernandes GC, Berardinelli GN, Andrade CEM, Neto MC, Romagnolo LGC, Campacci N, Scapulatempo-Neto C, Reis RM, Palmero EI
Cancer Genet 2021 Jun;254-255:82-91. Epub 2021 Feb 14 doi: 10.1016/j.cancergen.2021.02.003. PMID: 33647816
Lee SY, Kim DW, Shin YK, Ihn MH, Lee SM, Oh HK, Ku JL, Jeong SY, Lee JB, Ahn S, Won S, Kang SB
Cancer Res Treat 2016 Apr;48(2):668-75. Epub 2015 Jun 5 doi: 10.4143/crt.2014.288. PMID: 26044159Free PMC Article
Galiatsatos P, Rothenmund H, Aubin S, Foulkes WD
Dig Dis Sci 2015 Aug;60(8):2246-50. Epub 2015 Mar 19 doi: 10.1007/s10620-015-3626-8. PMID: 25786861

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