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Chronic decreased circulating IgD

MedGen UID:
1713830
•Concept ID:
C5398001
•
Finding
Synonym: Chronic decreased IgM in blood
 
HPO: HP:0033016

Definition

A lasting reduction beneath the normal level of total immunoglobulin D (IgD) in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChronic decreased circulating IgD

Recent clinical studies

Etiology

High serum immunoglobulin D levels in systemic lupus erythematosus: more to be found?
Liang P, Huang Q, Xu Y, Chen L, Li J, Xu A, Yang Q
Clin Rheumatol 2023 Apr;42(4):1069-1076. Epub 2022 Dec 30 doi: 10.1007/s10067-022-06457-9. PMID: 36585530
Decreased of BAFF-R expression and B cells maturation in patients with hepatitis B virus-related hepatocellular carcinoma.
Khlaiphuengsin A, Chuaypen N, Sodsai P, Buranapraditkun S, Boonpiyathad T, Hirankarn N, Tangkijvanich P
World J Gastroenterol 2020 May 28;26(20):2645-2656. doi: 10.3748/wjg.v26.i20.2645. PMID: 32523317Free PMC Article
Remodeling of B-Cell Subsets in Blood during Pegylated IFNα-2a Therapy in Patients with Chronic Hepatitis B Infection.
Aspord C, Bruder Costa J, Jacob MC, Dufeu-Duchesne T, Bertucci I, Pouget N, Brevot-Lutton O, Zoulim F, Bourliere M, Plumas J, Leroy V; ANRS HB06 PEGAN study group
PLoS One 2016;11(6):e0156200. Epub 2016 Jun 9 doi: 10.1371/journal.pone.0156200. PMID: 27281019Free PMC Article
Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease.
Sarantopoulos S, Stevenson KE, Kim HT, Washel WS, Bhuiya NS, Cutler CS, Alyea EP, Ho VT, Soiffer RJ, Antin JH, Ritz J
Blood 2011 Feb 17;117(7):2275-83. Epub 2010 Nov 19 doi: 10.1182/blood-2010-10-307819. PMID: 21097674Free PMC Article

Diagnosis

Decreased of BAFF-R expression and B cells maturation in patients with hepatitis B virus-related hepatocellular carcinoma.
Khlaiphuengsin A, Chuaypen N, Sodsai P, Buranapraditkun S, Boonpiyathad T, Hirankarn N, Tangkijvanich P
World J Gastroenterol 2020 May 28;26(20):2645-2656. doi: 10.3748/wjg.v26.i20.2645. PMID: 32523317Free PMC Article
Disturbed homeostasis and multiple signaling defects in the peripheral blood B-cell compartment of patients with severe chronic sarcoidosis.
Lee NS, Barber L, Akula SM, Sigounas G, Kataria YP, Arce S
Clin Vaccine Immunol 2011 Aug;18(8):1306-16. Epub 2011 Jun 8 doi: 10.1128/CVI.05118-11. PMID: 21653741Free PMC Article

Therapy

Remodeling of B-Cell Subsets in Blood during Pegylated IFNα-2a Therapy in Patients with Chronic Hepatitis B Infection.
Aspord C, Bruder Costa J, Jacob MC, Dufeu-Duchesne T, Bertucci I, Pouget N, Brevot-Lutton O, Zoulim F, Bourliere M, Plumas J, Leroy V; ANRS HB06 PEGAN study group
PLoS One 2016;11(6):e0156200. Epub 2016 Jun 9 doi: 10.1371/journal.pone.0156200. PMID: 27281019Free PMC Article
Recovery of B-cell homeostasis after rituximab in chronic graft-versus-host disease.
Sarantopoulos S, Stevenson KE, Kim HT, Washel WS, Bhuiya NS, Cutler CS, Alyea EP, Ho VT, Soiffer RJ, Antin JH, Ritz J
Blood 2011 Feb 17;117(7):2275-83. Epub 2010 Nov 19 doi: 10.1182/blood-2010-10-307819. PMID: 21097674Free PMC Article

Prognosis

High serum immunoglobulin D levels in systemic lupus erythematosus: more to be found?
Liang P, Huang Q, Xu Y, Chen L, Li J, Xu A, Yang Q
Clin Rheumatol 2023 Apr;42(4):1069-1076. Epub 2022 Dec 30 doi: 10.1007/s10067-022-06457-9. PMID: 36585530
Remodeling of B-Cell Subsets in Blood during Pegylated IFNα-2a Therapy in Patients with Chronic Hepatitis B Infection.
Aspord C, Bruder Costa J, Jacob MC, Dufeu-Duchesne T, Bertucci I, Pouget N, Brevot-Lutton O, Zoulim F, Bourliere M, Plumas J, Leroy V; ANRS HB06 PEGAN study group
PLoS One 2016;11(6):e0156200. Epub 2016 Jun 9 doi: 10.1371/journal.pone.0156200. PMID: 27281019Free PMC Article

Clinical prediction guides

High serum immunoglobulin D levels in systemic lupus erythematosus: more to be found?
Liang P, Huang Q, Xu Y, Chen L, Li J, Xu A, Yang Q
Clin Rheumatol 2023 Apr;42(4):1069-1076. Epub 2022 Dec 30 doi: 10.1007/s10067-022-06457-9. PMID: 36585530
Altered distribution of peripheral blood memory B cells in humans chronically infected with Trypanosoma cruzi.
Fernández ER, Olivera GC, Quebrada Palacio LP, González MN, Hernandez-Vasquez Y, Sirena NM, Morán ML, Ledesma Patiño OS, Postan M
PLoS One 2014;9(8):e104951. Epub 2014 Aug 11 doi: 10.1371/journal.pone.0104951. PMID: 25111833Free PMC Article

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