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Sinus Bradycardia by ECG Finding

MedGen UID:
1714872
•Concept ID:
C5235162
•
Finding
Synonyms: Sinus Bradycardia; Sinus Bradycardia by EKG Finding

Definition

An electrocardiographic finding of abnormally slow heart rate with its origin in the sinus node. Thresholds for different age, gender, and patient populations exist. (CDISC) [from NCI]

Professional guidelines

PubMed

2021 PACES Expert Consensus Statement on the Indications and Management of Cardiovascular Implantable Electronic Devices in Pediatric Patients.
Writing Committee Members, Shah MJ, Silka MJ, Silva JNA, Balaji S, Beach CM, Benjamin MN, Berul CI, Cannon B, Cecchin F, Cohen MI, Dalal AS, Dechert BE, Foster A, Gebauer R, Gonzalez Corcia MC, Kannankeril PJ, Karpawich PP, Kim JJ, Krishna MR, Kubuš P, LaPage MJ, Mah DY, Malloy-Walton L, Miyazaki A, Motonaga KS, Niu MC, Olen M, Paul T, Rosenthal E, Saarel EV, Silvetti MS, Stephenson EA, Tan RB, Triedman J, Bergen NHV, Wackel PL
Heart Rhythm 2021 Nov;18(11):1888-1924. Epub 2021 Jul 29 doi: 10.1016/j.hrthm.2021.07.038. PMID: 34363988
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD
Circulation 2019 Aug 20;140(8):e382-e482. Epub 2018 Nov 6 doi: 10.1161/CIR.0000000000000628. PMID: 30586772
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD
J Am Coll Cardiol 2019 Aug 20;74(7):e51-e156. Epub 2018 Nov 6 doi: 10.1016/j.jacc.2018.10.044. PMID: 30412709

Recent clinical studies

Etiology

Electrocardiographic manifestations of COVID-19.
Long B, Brady WJ, Bridwell RE, Ramzy M, Montrief T, Singh M, Gottlieb M
Am J Emerg Med 2021 Mar;41:96-103. Epub 2020 Dec 29 doi: 10.1016/j.ajem.2020.12.060. PMID: 33412365Free PMC Article
Electrocardiographic interpretation in athletes.
Abela M, Sharma S
Minerva Cardiol Angiol 2021 Oct;69(5):533-556. Epub 2020 Oct 15 doi: 10.23736/S2724-5683.20.05331-1. PMID: 33059398
Evaluation and Management of Asymptomatic Bradyarrhythmias.
Çinier G, Haseeb S, Bazoukis G, Yeung C, Gül EE
Curr Cardiol Rev 2021;17(1):60-67. doi: 10.2174/1573403X16666200721154143. PMID: 32693770Free PMC Article
Opioids and Cardiac Arrhythmia: A Literature Review.
Behzadi M, Joukar S, Beik A
Med Princ Pract 2018;27(5):401-414. Epub 2018 Aug 2 doi: 10.1159/000492616. PMID: 30071529Free PMC Article
Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study.
Swedberg K, Komajda M, Böhm M, Borer JS, Ford I, Dubost-Brama A, Lerebours G, Tavazzi L; SHIFT Investigators
Lancet 2010 Sep 11;376(9744):875-85. doi: 10.1016/S0140-6736(10)61198-1. PMID: 20801500

Diagnosis

Sinus Node Dysfunction.
Hawks MK, Paul MLB, Malu OO
Am Fam Physician 2021 Aug 1;104(2):179-185. PMID: 34383451
2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD
Circulation 2019 Aug 20;140(8):e382-e482. Epub 2018 Nov 6 doi: 10.1161/CIR.0000000000000628. PMID: 30586772
Sick Sinus Syndrome.
De Ponti R, Marazzato J, Bagliani G, Leonelli FM, Padeletti L
Card Electrophysiol Clin 2018 Jun;10(2):183-195. doi: 10.1016/j.ccep.2018.02.002. PMID: 29784479
Fetal and Neonatal Arrhythmias.
Jaeggi E, Öhman A
Clin Perinatol 2016 Mar;43(1):99-112. doi: 10.1016/j.clp.2015.11.007. PMID: 26876124
Sick sinus syndrome: a review.
Semelka M, Gera J, Usman S
Am Fam Physician 2013 May 15;87(10):691-6. PMID: 23939447

Therapy

2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.
Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD
Circulation 2019 Aug 20;140(8):e382-e482. Epub 2018 Nov 6 doi: 10.1161/CIR.0000000000000628. PMID: 30586772
Opioids and Cardiac Arrhythmia: A Literature Review.
Behzadi M, Joukar S, Beik A
Med Princ Pract 2018;27(5):401-414. Epub 2018 Aug 2 doi: 10.1159/000492616. PMID: 30071529Free PMC Article
Fetal and Neonatal Arrhythmias.
Jaeggi E, Öhman A
Clin Perinatol 2016 Mar;43(1):99-112. doi: 10.1016/j.clp.2015.11.007. PMID: 26876124
Fetal arrhythmias.
Meijboom EJ, van Engelen AD, van de Beek EW, Weijtens O, Lautenschutz JM, Benatar AA
Curr Opin Cardiol 1994 Jan;9(1):97-102. doi: 10.1097/00001573-199401000-00012. PMID: 8199375
The tachycardia-bradycardia syndrome.
Kaplan BM
Med Clin North Am 1976 Jan;60(1):81-99. doi: 10.1016/s0025-7125(16)31921-6. PMID: 1107695

Prognosis

Sinus Node Dysfunction.
Hawks MK, Paul MLB, Malu OO
Am Fam Physician 2021 Aug 1;104(2):179-185. PMID: 34383451
Evaluation and Management of Asymptomatic Bradyarrhythmias.
Çinier G, Haseeb S, Bazoukis G, Yeung C, Gül EE
Curr Cardiol Rev 2021;17(1):60-67. doi: 10.2174/1573403X16666200721154143. PMID: 32693770Free PMC Article
Bradyarrhythmias in the elderly.
Kumar P, Kusumoto FM, Goldschlager N
Clin Geriatr Med 2012 Nov;28(4):703-15. doi: 10.1016/j.cger.2012.08.004. PMID: 23101579
Atrial fibrillation.
Aronow WS
Heart Dis 2002 Mar-Apr;4(2):91-101. doi: 10.1097/00132580-200203000-00006. PMID: 11975840
The tachycardia-bradycardia syndrome.
Kaplan BM
Med Clin North Am 1976 Jan;60(1):81-99. doi: 10.1016/s0025-7125(16)31921-6. PMID: 1107695

Clinical prediction guides

Sinus Node Dysfunction.
Hawks MK, Paul MLB, Malu OO
Am Fam Physician 2021 Aug 1;104(2):179-185. PMID: 34383451
Electrocardiographic interpretation in athletes.
Abela M, Sharma S
Minerva Cardiol Angiol 2021 Oct;69(5):533-556. Epub 2020 Oct 15 doi: 10.23736/S2724-5683.20.05331-1. PMID: 33059398
Cardiac characteristics and natural progression in Taiwanese patients with mucopolysaccharidosis III.
Lin HY, Chen MR, Lin SM, Hung CL, Niu DM, Chang TM, Chuang CK, Lin SP
Orphanet J Rare Dis 2019 Jun 13;14(1):140. doi: 10.1186/s13023-019-1112-7. PMID: 31196149Free PMC Article
Sick sinus syndrome.
Brignole M
Clin Geriatr Med 2002 May;18(2):211-27. doi: 10.1016/s0749-0690(02)00006-x. PMID: 12180244
ECG variants and cardiac arrhythmias in athletes: clinical relevance and prognostic importance.
Zehender M, Meinertz T, Keul J, Just H
Am Heart J 1990 Jun;119(6):1378-91. doi: 10.1016/s0002-8703(05)80189-9. PMID: 2191578

Recent systematic reviews

Systematic review of long QT syndrome identified during fetal life.
Chivers S, Ovadia C, Regan W, Zidere V, Vigneswaran T, Sharland G, Rosenthal E, Seed PT, Simpson JM, Williamson C
Heart Rhythm 2023 Apr;20(4):596-606. Epub 2022 Dec 22 doi: 10.1016/j.hrthm.2022.12.026. PMID: 36566891
Cardiovascular sequelae of dengue fever: a systematic review.
Rahim A, Hameed A, Ishaq U, Malik J, Zaidi SMJ, Khurshid H, Malik A, Satti DI, Naz H
Expert Rev Cardiovasc Ther 2022 Jun;20(6):465-479. Epub 2022 Jun 2 doi: 10.1080/14779072.2022.2082945. PMID: 35612830
Predictors of permanent pacemaker insertion after mitral valve replacement: A systematic review.
Ghauri H, Iqbal R, Ahmed S, Ashraf A, Khan MSQ, Malik J, Zaidi SMJ, Almas T
Pacing Clin Electrophysiol 2022 May;45(5):681-687. Epub 2022 Apr 9 doi: 10.1111/pace.14484. PMID: 35304920
Swallow syncope: a case report and review of literature.
Siew KSW, Tan MP, Hilmi IN, Loch A
BMC Cardiovasc Disord 2019 Aug 7;19(1):191. doi: 10.1186/s12872-019-1174-4. PMID: 31391000Free PMC Article
Mad honey intoxication: A systematic review on the 1199 cases.
Silici S, Atayoglu AT
Food Chem Toxicol 2015 Dec;86:282-90. Epub 2015 Nov 10 doi: 10.1016/j.fct.2015.10.018. PMID: 26547022

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