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Abnormal diffusion weighted cerebral MRI morphology

MedGen UID:
1716407
Concept ID:
C5397636
Finding
Synonyms: Diffusion weighted imaging (DWI) abnormality; Diffusion weighted magnetic resonance imaging (DWI) abnormality; MRI diffusion abnormality of the cerebrum
 
HPO: HP:0032615

Definition

A diffusion abnormality observed in diffusion-weighted magnetic resonance imaging (MRI) of the brain. Molecular diffusion refers to the notion that any type of molecule in a fluid (eg, water) is randomly displaced as the molecule is agitated by thermal energy. Restricted diffusion of water appears bright on diffusion-weighted images. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal diffusion weighted cerebral MRI morphology

Conditions with this feature

Mitochondrial complex 1 deficiency, nuclear type 34
MedGen UID:
1720533
Concept ID:
C5394053
Disease or Syndrome

Professional guidelines

PubMed

Neonatologist Society, Chinese Medical Doctor Association; Editorial Board of Chinese Journal of Contemporary Pediatrics
Zhongguo Dang Dai Er Ke Za Zhi 2022 Jan 15;24(1):14-25. doi: 10.7499/j.issn.1008-8830.2110018. PMID: 35177171Free PMC Article
Hegde AN, Mohan S, Lath N, Lim CC
Radiographics 2011 Jan-Feb;31(1):5-30. doi: 10.1148/rg.311105041. PMID: 21257930
Finsterer J
Eur J Neurol 2009 Nov;16(11):1178-84. Epub 2009 Sep 23 doi: 10.1111/j.1468-1331.2009.02789.x. PMID: 19780807

Recent clinical studies

Etiology

Cairns J, Vavasour IM, Traboulsee A, Carruthers R, Kolind SH, Li DKB, Moore GRW, Laule C
J Neuroimaging 2022 Jan;32(1):5-16. Epub 2021 Nov 9 doi: 10.1111/jon.12945. PMID: 34752664
Haghighi-Morad M, Naseri Z, Jamshidi N, Hassanian-Moghaddam H, Zamani N, Ahmad-Molaei L
BMC Med Imaging 2020 Jan 17;20(1):6. doi: 10.1186/s12880-020-0410-9. PMID: 31952488Free PMC Article
Duncan JS, Winston GP, Koepp MJ, Ourselin S
Lancet Neurol 2016 Apr;15(4):420-33. Epub 2016 Feb 24 doi: 10.1016/S1474-4422(15)00383-X. PMID: 26925532Free PMC Article
Engelter ST, Wetzel SG, Bonati LH, Fluri F, Lyrer PA
Swiss Med Wkly 2008 Dec 13;138(49-50):729-40. doi: 10.4414/smw.2008.12249. PMID: 19130326
Brunel H, Girard N, Confort-Gouny S, Viola A, Chaumoitre K, D'ercole C, Figarella-Branger D, Raybaud C, Cozzone P, Panuel M
J Neuroradiol 2004 Mar;31(2):123-37. doi: 10.1016/s0150-9861(04)96979-9. PMID: 15094650

Diagnosis

Kroenke CD
J Magn Reson 2018 Jul;292:106-116. Epub 2018 Apr 26 doi: 10.1016/j.jmr.2018.04.011. PMID: 29705039Free PMC Article
Meijer FJ, Goraj B
Front Biosci (Elite Ed) 2014 Jun 1;6(2):360-9. doi: 10.2741/E711. PMID: 24896211
Szabo K, Förster A, Gass A
Front Neurol Neurosci 2014;34:71-84. Epub 2014 Apr 16 doi: 10.1159/000357925. PMID: 24777132
Brooks DJ
Parkinsonism Relat Disord 2012 Jan;18 Suppl 1:S31-3. doi: 10.1016/S1353-8020(11)70012-8. PMID: 22166447
Hegde AN, Mohan S, Lath N, Lim CC
Radiographics 2011 Jan-Feb;31(1):5-30. doi: 10.1148/rg.311105041. PMID: 21257930

Therapy

Hosseinpour Z, Jonkman L, Oladosu O, Pridham G, Pike GB, Inglese M, Geurts JJ, Zhang Y
J Neurosci Methods 2022 Sep 1;379:109671. Epub 2022 Jul 9 doi: 10.1016/j.jneumeth.2022.109671. PMID: 35820450
Jeong JW, Lee MH, Fernandes N, Deol S, Mody S, Arslanturk S, Chinnam RB, Tan S
Pediatr Res 2022 May;91(6):1505-1515. Epub 2021 May 8 doi: 10.1038/s41390-021-01550-2. PMID: 33966055Free PMC Article
Heiss WD, Zaro-Weber O
Int J Stroke 2019 Jun;14(4):351-358. Epub 2019 Apr 1 doi: 10.1177/1747493019840936. PMID: 30935350
Vorona GA, Berman JI
Pediatr Radiol 2015 Sep;45 Suppl 3:S375-81. Epub 2015 Sep 7 doi: 10.1007/s00247-015-3277-0. PMID: 26346143
Engelter ST, Wetzel SG, Bonati LH, Fluri F, Lyrer PA
Swiss Med Wkly 2008 Dec 13;138(49-50):729-40. doi: 10.4414/smw.2008.12249. PMID: 19130326

Prognosis

Sagnier S, Sibon I
J Neurosci Res 2022 May;100(5):1171-1181. Epub 2019 Sep 9 doi: 10.1002/jnr.24525. PMID: 31498491
Assaf Y
Neuroimage 2019 Aug 15;197:677-688. Epub 2018 Jan 5 doi: 10.1016/j.neuroimage.2017.12.096. PMID: 29309898
Pandit AS, Ball G, Edwards AD, Counsell SJ
Neuroradiology 2013 Sep;55 Suppl 2:65-95. Epub 2013 Aug 14 doi: 10.1007/s00234-013-1242-x. PMID: 23942765
Laothamatas J, Sungkarat W, Hemachudha T
Adv Virus Res 2011;79:309-27. doi: 10.1016/B978-0-12-387040-7.00014-7. PMID: 21601052
Kim DW, Park JM, Yoon BW, Baek MJ, Kim JE, Kim S
J Neurol Sci 2004 Sep 15;224(1-2):107-11. doi: 10.1016/j.jns.2004.06.012. PMID: 15450780

Clinical prediction guides

Cairns J, Vavasour IM, Traboulsee A, Carruthers R, Kolind SH, Li DKB, Moore GRW, Laule C
J Neuroimaging 2022 Jan;32(1):5-16. Epub 2021 Nov 9 doi: 10.1111/jon.12945. PMID: 34752664
Sagnier S, Sibon I
J Neurosci Res 2022 May;100(5):1171-1181. Epub 2019 Sep 9 doi: 10.1002/jnr.24525. PMID: 31498491
Haghighi-Morad M, Naseri Z, Jamshidi N, Hassanian-Moghaddam H, Zamani N, Ahmad-Molaei L
BMC Med Imaging 2020 Jan 17;20(1):6. doi: 10.1186/s12880-020-0410-9. PMID: 31952488Free PMC Article
Pavlovic D, Pekic S, Stojanovic M, Popovic V
Pituitary 2019 Jun;22(3):270-282. doi: 10.1007/s11102-019-00957-9. PMID: 30929221
Mascalchi M, Vella A
Int Rev Neurobiol 2018;143:109-162. Epub 2018 Oct 29 doi: 10.1016/bs.irn.2018.09.011. PMID: 30473193

Recent systematic reviews

MacIver CL, Tax CMW, Jones DK, Peall KJ
Eur J Neurol 2022 Nov;29(11):3418-3448. Epub 2022 Jul 22 doi: 10.1111/ene.15483. PMID: 35785410Free PMC Article
Van't Hooft J, van der Lee JH, Opmeer BC, Aarnoudse-Moens CS, Leenders AG, Mol BW, de Haan TR
Syst Rev 2015 May 17;4:71. doi: 10.1186/s13643-015-0058-7. PMID: 25982565Free PMC Article
Baker ST, Yücel M, Fornito A, Allen NB, Lubman DI
Neurosci Biobehav Rev 2013 Sep;37(8):1713-23. Epub 2013 Jul 8 doi: 10.1016/j.neubiorev.2013.06.015. PMID: 23845745
Bühler M, Mann K
Alcohol Clin Exp Res 2011 Oct;35(10):1771-93. Epub 2011 Jul 20 doi: 10.1111/j.1530-0277.2011.01540.x. PMID: 21777260
Engelter ST, Wetzel SG, Bonati LH, Fluri F, Lyrer PA
Swiss Med Wkly 2008 Dec 13;138(49-50):729-40. doi: 10.4414/smw.2008.12249. PMID: 19130326

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