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Abnormal urine pH

MedGen UID:
1716739
•Concept ID:
C0855949
•
Finding
HPO: HP:0032943

Definition

A deviation of urine pH from the normal range of 4.5 to 7.8. [from HPO]

Professional guidelines

PubMed

Diagnosis and Management of Multiple Myeloma: A Review.
Cowan AJ, Green DJ, Kwok M, Lee S, Coffey DG, Holmberg LA, Tuazon S, Gopal AK, Libby EN
JAMA 2022 Feb 1;327(5):464-477. doi: 10.1001/jama.2022.0003. PMID: 35103762
Contemporary Management of Urinary Tract Infection in Children.
Mattoo TK, Shaikh N, Nelson CP
Pediatrics 2021 Feb;147(2) doi: 10.1542/peds.2020-012138. PMID: 33479164
Pathophysiology, diagnosis and management of nephrogenic diabetes insipidus.
Bockenhauer D, Bichet DG
Nat Rev Nephrol 2015 Oct;11(10):576-88. Epub 2015 Jun 16 doi: 10.1038/nrneph.2015.89. PMID: 26077742

Recent clinical studies

Etiology

MicroRNAs as Biomarkers for Birth Defects.
Seelan RS, Pisano MM, Greene RM
Microrna 2022;11(1):2-11. doi: 10.2174/2211536611666220215123423. PMID: 35168515
Antenatal hydronephrosis and fetal urine sampling.
Beksac MS, Beksac AT, Tanacan A, Mumusoglu S, Katlan D, Celik HT
Congenit Anom (Kyoto) 2020 Jan;60(1):4-9. Epub 2019 Jan 27 doi: 10.1111/cga.12324. PMID: 30629771
Incomplete Distal Renal Tubular Acidosis and Kidney Stones.
Fuster DG, Moe OW
Adv Chronic Kidney Dis 2018 Jul;25(4):366-374. doi: 10.1053/j.ackd.2018.05.007. PMID: 30139463Free PMC Article
The neurogenic bladder: introducing four contributions.
Proesmans W
Pediatr Nephrol 2008 Apr;23(4):537-40. Epub 2008 Feb 16 doi: 10.1007/s00467-008-0768-3. PMID: 18278519
Uric acid nephrolithiasis.
Liebman SE, Taylor JG, Bushinsky DA
Curr Rheumatol Rep 2007 Jun;9(3):251-7. doi: 10.1007/s11926-007-0040-z. PMID: 17531180

Diagnosis

MicroRNAs as Biomarkers for Birth Defects.
Seelan RS, Pisano MM, Greene RM
Microrna 2022;11(1):2-11. doi: 10.2174/2211536611666220215123423. PMID: 35168515
Prion diseases: New considerations.
Annus Á, Csáti A, Vécsei L
Clin Neurol Neurosurg 2016 Nov;150:125-132. Epub 2016 Sep 17 doi: 10.1016/j.clineuro.2016.09.006. PMID: 27656779
Understanding hypernatremia.
Sam R, Feizi I
Am J Nephrol 2012;36(1):97-104. Epub 2012 Jun 27 doi: 10.1159/000339625. PMID: 22739333
Urodynamics.
Gleason DM, Bottaccini MR, Drach GW
J Urol 1976 Apr;115(4):356-61. doi: 10.1016/s0022-5347(17)59203-4. PMID: 772236
Hematospermia.
Leary FJ
J Fam Pract 1975 Jun;2(3):185-6. PMID: 1097579

Therapy

Incomplete Distal Renal Tubular Acidosis and Kidney Stones.
Fuster DG, Moe OW
Adv Chronic Kidney Dis 2018 Jul;25(4):366-374. doi: 10.1053/j.ackd.2018.05.007. PMID: 30139463Free PMC Article
Preeclampsia: multiple approaches for a multifactorial disease.
Pennington KA, Schlitt JM, Jackson DL, Schulz LC, Schust DJ
Dis Model Mech 2012 Jan;5(1):9-18. doi: 10.1242/dmm.008516. PMID: 22228789Free PMC Article
Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months.
Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB
Pediatrics 2011 Sep;128(3):595-610. Epub 2011 Aug 28 doi: 10.1542/peds.2011-1330. PMID: 21873693
Formaldehyde stress.
He R, Lu J, Miao J
Sci China Life Sci 2010 Dec;53(12):1399-404. Epub 2010 Dec 23 doi: 10.1007/s11427-010-4112-3. PMID: 21181340
Vasopressin receptor antagonists.
Greenberg A, Verbalis JG
Kidney Int 2006 Jun;69(12):2124-30. Epub 2006 May 3 doi: 10.1038/sj.ki.5000432. PMID: 16672911

Prognosis

MicroRNAs as Biomarkers for Birth Defects.
Seelan RS, Pisano MM, Greene RM
Microrna 2022;11(1):2-11. doi: 10.2174/2211536611666220215123423. PMID: 35168515
Cytologically targeted next-generation sequencing: a synergy for diagnosing urothelial carcinoma.
Harris T, Sheel A, Zong Y, Hutchinson LM, Cornejo KM, Bubendorf L, Yates J, Fischer AH
J Am Soc Cytopathol 2021 Jan-Feb;10(1):94-102. Epub 2020 Oct 14 doi: 10.1016/j.jasc.2020.10.001. PMID: 33184010
"Classical organic acidurias": diagnosis and pathogenesis.
Villani GR, Gallo G, Scolamiero E, Salvatore F, Ruoppolo M
Clin Exp Med 2017 Aug;17(3):305-323. Epub 2016 Sep 9 doi: 10.1007/s10238-016-0435-0. PMID: 27613073
Urinary biomarkers for renal tract malformations.
Magalhães P, Schanstra JP, Carrick E, Mischak H, Zürbig P
Expert Rev Proteomics 2016 Dec;13(12):1121-1129. Epub 2016 Nov 15 doi: 10.1080/14789450.2016.1254555. PMID: 27791437Free PMC Article
Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months.
Subcommittee on Urinary Tract Infection, Steering Committee on Quality Improvement and Management, Roberts KB
Pediatrics 2011 Sep;128(3):595-610. Epub 2011 Aug 28 doi: 10.1542/peds.2011-1330. PMID: 21873693

Clinical prediction guides

MicroRNAs as Biomarkers for Birth Defects.
Seelan RS, Pisano MM, Greene RM
Microrna 2022;11(1):2-11. doi: 10.2174/2211536611666220215123423. PMID: 35168515
Cytologically targeted next-generation sequencing: a synergy for diagnosing urothelial carcinoma.
Harris T, Sheel A, Zong Y, Hutchinson LM, Cornejo KM, Bubendorf L, Yates J, Fischer AH
J Am Soc Cytopathol 2021 Jan-Feb;10(1):94-102. Epub 2020 Oct 14 doi: 10.1016/j.jasc.2020.10.001. PMID: 33184010
Lights and Shadows of TORCH Infection Proteomics.
Macedo-da-Silva J, Marinho CRF, Palmisano G, Rosa-Fernandes L
Genes (Basel) 2020 Aug 5;11(8) doi: 10.3390/genes11080894. PMID: 32764347Free PMC Article
Antenatal hydronephrosis and fetal urine sampling.
Beksac MS, Beksac AT, Tanacan A, Mumusoglu S, Katlan D, Celik HT
Congenit Anom (Kyoto) 2020 Jan;60(1):4-9. Epub 2019 Jan 27 doi: 10.1111/cga.12324. PMID: 30629771
Prenatal imaging findings in fetal Zika virus infection.
Araujo Júnior E, Carvalho FH, Tonni G, Werner H
Curr Opin Obstet Gynecol 2017 Apr;29(2):95-105. doi: 10.1097/GCO.0000000000000345. PMID: 28134669

Recent systematic reviews

Potential Renal Damage Biomarkers in Alport Syndrome-A Review of the Literature.
Gomes AM, Lopes D, Almeida C, Santos S, Malheiro J, Lousa I, Caldas Afonso A, Beirão I
Int J Mol Sci 2022 Jun 30;23(13) doi: 10.3390/ijms23137276. PMID: 35806283Free PMC Article
Biomarkers of acute kidney injury in pediatric cardiac surgery.
Cavalcante CTMB, Cavalcante MB, Castello Branco KMP, Chan T, Maia ICL, Pompeu RG, de Oliveira Telles AC, Brito AKM, Libório AB
Pediatr Nephrol 2022 Jan;37(1):61-78. Epub 2021 May 25 doi: 10.1007/s00467-021-05094-9. PMID: 34036445
Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis.
Rompianesi G, Hann A, Komolafe O, Pereira SP, Davidson BR, Gurusamy KS
Cochrane Database Syst Rev 2017 Apr 21;4(4):CD012010. doi: 10.1002/14651858.CD012010.pub2. PMID: 28431198Free PMC Article
First trimester ultrasound tests alone or in combination with first trimester serum tests for Down's syndrome screening.
Alldred SK, Takwoingi Y, Guo B, Pennant M, Deeks JJ, Neilson JP, Alfirevic Z
Cochrane Database Syst Rev 2017 Mar 15;3(3):CD012600. doi: 10.1002/14651858.CD012600. PMID: 28295158Free PMC Article
Non-vector-borne transmission of Zika virus: A systematic review.
Grischott F, Puhan M, Hatz C, Schlagenhauf P
Travel Med Infect Dis 2016 Jul-Aug;14(4):313-30. Epub 2016 Jul 15 doi: 10.1016/j.tmaid.2016.07.002. PMID: 27425793

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