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Unresectable Periampullary Adenocarcinoma

MedGen UID:
1717157
•Concept ID:
C5236959
•
Neoplastic Process

Definition

Adenocarcinoma that arises from the periampullary region and is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Periampullary Adenocarcinoma

Professional guidelines

PubMed

Opportunities of improvement in the management of pancreatic and periampullary tumors.
Nordby T, Ikdahl T, Lothe IM, Ånonsen K, Hauge T, Edwin B, Line PD, Labori KJ, Buanes T
Scand J Gastroenterol 2013 May;48(5):617-25. doi: 10.3109/00365521.2013.781218. PMID: 23597153Free PMC Article
Evolving concepts regarding the use of radiotherapy in the adjuvant management of periampullary pancreatic adenocarcinoma.
Abrams RA
Cancer J 2012 Nov-Dec;18(6):624-32. doi: 10.1097/PPO.0b013e3182758c84. PMID: 23187851
Diagnosis and treatment of malignant oddian tumors.
Suter M, Cuttat JF
Helv Chir Acta 1989 Dec;56(4):471-9. PMID: 2632471

Recent clinical studies

Etiology

Staging laparoscopy in patients scheduled for pancreaticoduodenectomy minimizes hospitalization in the remaining life time when metastatic carcinoma is found.
Beenen E, van Roest MH, Sieders E, Peeters PM, Porte RJ, de Boer MT, de Jong KP
Eur J Surg Oncol 2014 Aug;40(8):989-94. Epub 2014 Feb 8 doi: 10.1016/j.ejso.2013.12.019. PMID: 24582004
Prospective study of gastric outlet obstruction in unresectable periampullary adenocarcinoma.
Shyr YM, Su CH, Wu CW, Lui WY
World J Surg 2000 Jan;24(1):60-4; discussion 64-5. doi: 10.1007/s002689910012. PMID: 10594205
Surgical palliation of unresectable periampullary adenocarcinoma in the 1990s.
Sohn TA, Lillemoe KD, Cameron JL, Huang JJ, Pitt HA, Yeo CJ
J Am Coll Surg 1999 Jun;188(6):658-66; discussion 666-9. doi: 10.1016/s1072-7515(99)00049-6. PMID: 10359359
Current status of surgical palliation of periampullary carcinoma.
Lillemoe KD, Sauter PK, Pitt HA, Yeo CJ, Cameron JL
Surg Gynecol Obstet 1993 Jan;176(1):1-10. PMID: 7678945

Diagnosis

Prospective study of gastric outlet obstruction in unresectable periampullary adenocarcinoma.
Shyr YM, Su CH, Wu CW, Lui WY
World J Surg 2000 Jan;24(1):60-4; discussion 64-5. doi: 10.1007/s002689910012. PMID: 10594205
Current status of surgical palliation of periampullary carcinoma.
Lillemoe KD, Sauter PK, Pitt HA, Yeo CJ, Cameron JL
Surg Gynecol Obstet 1993 Jan;176(1):1-10. PMID: 7678945

Therapy

Staging laparoscopy in patients scheduled for pancreaticoduodenectomy minimizes hospitalization in the remaining life time when metastatic carcinoma is found.
Beenen E, van Roest MH, Sieders E, Peeters PM, Porte RJ, de Boer MT, de Jong KP
Eur J Surg Oncol 2014 Aug;40(8):989-94. Epub 2014 Feb 8 doi: 10.1016/j.ejso.2013.12.019. PMID: 24582004

Prognosis

Prospective study of gastric outlet obstruction in unresectable periampullary adenocarcinoma.
Shyr YM, Su CH, Wu CW, Lui WY
World J Surg 2000 Jan;24(1):60-4; discussion 64-5. doi: 10.1007/s002689910012. PMID: 10594205
Surgical palliation of unresectable periampullary adenocarcinoma in the 1990s.
Sohn TA, Lillemoe KD, Cameron JL, Huang JJ, Pitt HA, Yeo CJ
J Am Coll Surg 1999 Jun;188(6):658-66; discussion 666-9. doi: 10.1016/s1072-7515(99)00049-6. PMID: 10359359
Current status of surgical palliation of periampullary carcinoma.
Lillemoe KD, Sauter PK, Pitt HA, Yeo CJ, Cameron JL
Surg Gynecol Obstet 1993 Jan;176(1):1-10. PMID: 7678945

Clinical prediction guides

Current status of surgical palliation of periampullary carcinoma.
Lillemoe KD, Sauter PK, Pitt HA, Yeo CJ, Cameron JL
Surg Gynecol Obstet 1993 Jan;176(1):1-10. PMID: 7678945

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