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Skin Verrucous Carcinoma

MedGen UID:
1718207
•Concept ID:
C5237206
•
Neoplastic Process

Definition

A verrucous carcinoma that arises from the skin. It usually affects the palms, soles, and distal digits. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin Verrucous Carcinoma

Professional guidelines

PubMed

Surgical treatment of verrucous carcinoma: a review.
Fawaz B, Vieira C, Decker A, Lawrence N
J Dermatolog Treat 2022 Jun;33(4):1811-1815. Epub 2022 Jun 13 doi: 10.1080/09546634.2021.1914312. PMID: 33849379
Acral melanoma foot lesions. Part 2: clinical presentation, diagnosis, and management.
Desai A, Ugorji R, Khachemoune A
Clin Exp Dermatol 2018 Mar;43(2):117-123. Epub 2017 Dec 13 doi: 10.1111/ced.13323. PMID: 29235153
Clinical pathologic correlations for diagnosis and treatment of nail disorders.
Kovich OI, Soldano AC
Dermatol Ther 2007 Jan-Feb;20(1):11-6. doi: 10.1111/j.1529-8019.2007.00107.x. PMID: 17403256

Recent clinical studies

Etiology

Xeroderma pigmentosum: case report.
Cordeiro MEC, Real LC, Simoni AGP
Rev Paul Pediatr 2023;41:e2021390. Epub 2023 Mar 13 doi: 10.1590/1984-0462/2023/41/2021390. PMID: 36921168Free PMC Article
Recent advances in cutaneous HPV infection.
Shimizu A, Yamaguchi R, Kuriyama Y
J Dermatol 2023 Mar;50(3):290-298. Epub 2023 Jan 5 doi: 10.1111/1346-8138.16697. PMID: 36601717
WHO 2022 classification of penile and scrotal cancers: updates and evolution.
Menon S, Moch H, Berney DM, Cree IA, Srigley JR, Tsuzuki T, Compérat E, Hartmann A, Netto G, Rubin MA, Gill AJ, Turajlic S, Tan PH, Raspollini MR, Tickoo SK, Amin MB
Histopathology 2023 Mar;82(4):508-520. Epub 2022 Nov 9 doi: 10.1111/his.14824. PMID: 36221864
Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease.
Burton KA, Ashack KA, Khachemoune A
Am J Clin Dermatol 2016 Oct;17(5):491-508. doi: 10.1007/s40257-016-0207-3. PMID: 27358187
Psoriasiform keratosis.
Walsh SN, Hurt MA, Santa Cruz DJ
Am J Dermatopathol 2007 Apr;29(2):137-40. doi: 10.1097/01.dad.0000246177.63145.b3. PMID: 17414434

Diagnosis

Cutaneous Verrucous Carcinomas: A Review.
Ye Q, Jia M, Deng LJ, Fang S
J Cutan Med Surg 2023 Mar-Apr;27(2):150-156. Epub 2023 Feb 14 doi: 10.1177/12034754231155895. PMID: 36789508
Surgical treatment of verrucous carcinoma: a review.
Fawaz B, Vieira C, Decker A, Lawrence N
J Dermatolog Treat 2022 Jun;33(4):1811-1815. Epub 2022 Jun 13 doi: 10.1080/09546634.2021.1914312. PMID: 33849379
Pyoderma Gangranosum-Like Blastomycosis.
Mak J, Al Habeeb A, Al Kalabi M, Alavi A
J Cutan Med Surg 2018 Sep/Oct;22(5):519-521. Epub 2018 Feb 28 doi: 10.1177/1203475418760460. PMID: 29486592
Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease.
Burton KA, Ashack KA, Khachemoune A
Am J Clin Dermatol 2016 Oct;17(5):491-508. doi: 10.1007/s40257-016-0207-3. PMID: 27358187
Nail tumors.
Richert B, Lecerf P, Caucanas M, André J
Clin Dermatol 2013 Sep-Oct;31(5):602-17. doi: 10.1016/j.clindermatol.2013.06.014. PMID: 24079590

Therapy

Surgical treatment of verrucous carcinoma: a review.
Fawaz B, Vieira C, Decker A, Lawrence N
J Dermatolog Treat 2022 Jun;33(4):1811-1815. Epub 2022 Jun 13 doi: 10.1080/09546634.2021.1914312. PMID: 33849379
Cancer Immunoprevention: Current Status and Future Directions.
Keshavarz-Fathi M, Rezaei N
Arch Immunol Ther Exp (Warsz) 2021 Feb 27;69(1):3. doi: 10.1007/s00005-021-00604-x. PMID: 33638703
Atypical presentations of cutaneous leishmaniasis: A systematic review.
Meireles CB, Maia LC, Soares GC, Teodoro IPP, Gadelha MDSV, da Silva CGL, de Lima MAP
Acta Trop 2017 Aug;172:240-254. Epub 2017 May 17 doi: 10.1016/j.actatropica.2017.05.022. PMID: 28526427
Squamous cell carcinoma of the skin.
Rudolph R, Zelac DE
Plast Reconstr Surg 2004 Nov;114(6):82e-94e. doi: 10.1097/01.prs.0000138243.45735.8a. PMID: 15509920
Histopathology of cutaneous squamous cell carcinoma and its variants.
Kane CL, Keehn CA, Smithberger E, Glass LF
Semin Cutan Med Surg 2004 Mar;23(1):54-61. doi: 10.1016/s1085-5629(03)00088-9. PMID: 15095916

Prognosis

WHO 2022 classification of penile and scrotal cancers: updates and evolution.
Menon S, Moch H, Berney DM, Cree IA, Srigley JR, Tsuzuki T, Compérat E, Hartmann A, Netto G, Rubin MA, Gill AJ, Turajlic S, Tan PH, Raspollini MR, Tickoo SK, Amin MB
Histopathology 2023 Mar;82(4):508-520. Epub 2022 Nov 9 doi: 10.1111/his.14824. PMID: 36221864
Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease.
Burton KA, Ashack KA, Khachemoune A
Am J Clin Dermatol 2016 Oct;17(5):491-508. doi: 10.1007/s40257-016-0207-3. PMID: 27358187
Nail tumors.
Richert B, Lecerf P, Caucanas M, André J
Clin Dermatol 2013 Sep-Oct;31(5):602-17. doi: 10.1016/j.clindermatol.2013.06.014. PMID: 24079590
Psoriasiform keratosis.
Walsh SN, Hurt MA, Santa Cruz DJ
Am J Dermatopathol 2007 Apr;29(2):137-40. doi: 10.1097/01.dad.0000246177.63145.b3. PMID: 17414434
Verrucous carcinoma of the skin and mucosa.
Schwartz RA
J Am Acad Dermatol 1995 Jan;32(1):1-21; quiz 22-4. doi: 10.1016/0190-9622(95)90177-9. PMID: 7822496

Clinical prediction guides

Pseudoepitheliomatous keratotic and micaceous balanitis: a series of eight cases.
Spencer A, Watchorn RE, Kravvas G, Ben-Salha I, Haider A, Francis N, Freeman A, Alnajjar HM, Muneer A, Bunker CB
J Eur Acad Dermatol Venereol 2022 Oct;36(10):1851-1856. Epub 2022 Jun 29 doi: 10.1111/jdv.18328. PMID: 35695159
Cutaneous Squamous Cell Carcinoma: A Review of High-Risk and Metastatic Disease.
Burton KA, Ashack KA, Khachemoune A
Am J Clin Dermatol 2016 Oct;17(5):491-508. doi: 10.1007/s40257-016-0207-3. PMID: 27358187
Verrucous carcinoma of the skin: a report on 5 Japanese cases.
Terada T
Ann Diagn Pathol 2011 Jun;15(3):175-80. Epub 2011 Mar 10 doi: 10.1016/j.anndiagpath.2010.11.008. PMID: 21396866
Squamous cell carcinoma of the skin.
Rudolph R, Zelac DE
Plast Reconstr Surg 2004 Nov;114(6):82e-94e. doi: 10.1097/01.prs.0000138243.45735.8a. PMID: 15509920
Condylomata acuminata (genital warts). An epidemiologic view.
Chuang TY
J Am Acad Dermatol 1987 Feb;16(2 Pt 1):376-84. doi: 10.1016/s0190-9622(87)70053-x. PMID: 3029192

Recent systematic reviews

Epithelioma Cuniculatum (Plantar Verrucous Carcinoma): A Systematic Review of Treatment Options.
Shwe Daniel S, Cox SV, Kraus CN, Elsensohn AN
Cutis 2023 Feb;111(2):E19-E24. doi: 10.12788/cutis.0720. PMID: 37075193
Surgical treatment of verrucous carcinoma: a review.
Fawaz B, Vieira C, Decker A, Lawrence N
J Dermatolog Treat 2022 Jun;33(4):1811-1815. Epub 2022 Jun 13 doi: 10.1080/09546634.2021.1914312. PMID: 33849379
Esophageal carcinoma cuniculatum: systematic review of the literature and report of two cases.
Lai Q, de Giacomo T, Consolo A, Castrovillari M, Melandro F, Cerbelli B, Pernazza A, Berloco PB, d'Amati G, Francioni F
Pathol Res Pract 2019 Oct;215(10):152602. Epub 2019 Aug 17 doi: 10.1016/j.prp.2019.152602. PMID: 31472995
Atypical presentations of cutaneous leishmaniasis: A systematic review.
Meireles CB, Maia LC, Soares GC, Teodoro IPP, Gadelha MDSV, da Silva CGL, de Lima MAP
Acta Trop 2017 Aug;172:240-254. Epub 2017 May 17 doi: 10.1016/j.actatropica.2017.05.022. PMID: 28526427

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